2021 Ford F-250 Super Duty Cooling and Climate Controls

Essential 2021 Ford F-250 Super Duty Cooling and Climate Controls

Mahle – Water Pipe O-Ring (Part No.G2026948678MAH)

Water Pipe O-Ring

from

$1.41
Water Pipe O-Ring

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-272)

HVAC Blend Door Actuator: 1 Piece

from

$60.99
This air door actuator directly replaces the original actuator on specific vehicle years, makes, models, configurations and positions to restore proper HVAC operation. Please note that many vehicles have several different air door actuators, which are designed for specific positions and functions in the vehicle. To ensure you have what you need, carefully review the application notes for this part to verify it matches the position and function of the actuator you need to replace. In some online ordering systems, you may need to enter your vehicle information first to see the application notes for your vehicle. If you don’t know which actuator position you need to replace, consult a qualified service technician.

Product Features:
  • Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
  • Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
  • Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
  • Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience
See More

MAHLE Original – Water Pump Mounting (Part No.K32242)

Water Pump Mounting

from

$8.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Motorcraft – Motorcraft Expansion Tank Cap (Part No.G1040328187MTR)

Motorcraft Expansion Tank Cap

from

$7.81
High-quality caps for Ford and Lincoln vehicles.

Product Features:
  • Standard and safety vent radiator pressure caps available
  • Extensive coverage for most cars and trucks, as well as farm and construction equipment
  • Swivel-seal radiator caps are designed to provide increased durability and can be removed without damage to the rubber atmospheric seal
  • Zinc-plated to resist corrosion and rust
  • Pressure valve springs are made of stainless steel to maintain calibrated pressure throughout the service life
  • Rubber pressure valve gasket resists high temperatures and deterioration from coolant and additives
  • Pressure and vacuum relief features help extend radiator and hose life
  • Prevent accidental cap removal with positive low-pressure stop feature
See More

MAHLE Original – Engine Coolant Thermostat Housing Gasket (Part No.C32601)

Engine Coolant Thermostat Housing Gasket

from

$7.99
MAHLE gaskets provide world class sealing products trusted by OEMs & Technicians around the globe.

Product Features:
  • All MAHLE gaskets meet or exceed the original equipment specifications providing the finest sealing products available
  • MAHLE gaskets utilizes OE equivalent or better materials in all our gaskets
  • MAHLE gaskets is the leader in Domestic, Asian and European applications
  • The contents of MAHLE gaskets are packaged in shrink wrapped tray, giving you the added security of knowing that you have the right parts, prior to opening the package
See More

Carquest Premium – Heater Core (Part No.910741)

Heater Core

from

$140.99
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications. Carquest Premium provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability. Carquest Premium offers certified heater cores that meet or exceed OE specifications and are all fitment checked in the actual vehicle’s HVAC heater module and are, thus, ready to be installed right out of the box for a “Drop-In Fit”. Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.

Product Features:
  • All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
  • Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
  • Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
  • Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
  • Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts
See More

KAI – A/C Accumulator, V8 Engine (Part No.ACM010423)

A/C Accumulator, V8 Engine

from

$59.99
New Standard Replacement A/C Accumulator, V8 Engine

Product Features:
  • V8 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
See More

Factory Air – Engine Coolant Temperature Sensor (Part No.36447)

Engine Coolant Temperature Sensor

from

$27.49
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Brass construction for accurate temperature sensing
  • Color coded for easy identification
  • Zinc coated terminal to resist corrosion
See More

Carquest Premium – AC Pressure Switch (Part No.ABA1008)

AC Pressure Switch

from

$52.99
The Premium CarQuest Vehicle Solutions line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Switch monitors system pressures, aiding in proper and efficient control of the compresso

Product Features:
  • Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to meet or exceed OE performance and to meet the uncompromising demands of service professionals.
  • Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Switch.
  • All units are tested using advanced end-of-line equipment that pressurize the A/C Pressure Switch, confirm proper calibration and functionality, and check for leaks to ensure each A/C Pressure Switch meets manufacturing specifications before packaging.
  • All units are tested using automated end-of-line testing equipment pressurizing the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging.
See More

Carquest Premium – Radiator Cap Tester Adapter (Part No.12021)

Radiator Cap Tester Adapter

from

$17.79
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
See More

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4196)

Engine Water Pump: New, Gasket/Seals Included

from

$57.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
See More

Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-591)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

from

$94.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
See More

Dorman – Help – Radiator Drain Cocks (Part No.61127)

Radiator Drain Cocks

from

$6.99
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.

Product Features:
  • Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
  • Durable construction – this part is made of quality materials for a long service life
  • Saves money – offers original equipment quality at a competitive price
  • Quality assured – this petcock has undergone virtual testing to assure proper fit and function
See More

Dorman – Help – Radiator Drain Cocks (Part No.61134)

Radiator Drain Cocks

from

$7.79
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.

Product Features:
  • Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
  • Durable construction – this part is made of quality materials for a long service life
  • Saves money – offers original equipment quality at a competitive price
  • Quality assured – this petcock has undergone virtual testing to assure proper fit and function
See More

Carquest Premium – ABS Wheel Speed Sensor (Part No.ARA1904)

ABS Wheel Speed Sensor

from

$79.99
Advance Auto Parts is committed to providing high-quality ABS sensors. The entire manufacturing process is closely managed to deliver high quality products.

Product Features:
  • High grade materials that are equal to or better than OE provide durability and long service life
  • All ABS sensors are tested for proper fit, form, and function
  • Wire diameter and sheathing same or larger than OE to ensure product quality
  • Glass filled reinforced plastic for superior resistance to automotive fluids, dirt, salt and road debris
  • Includes all necessary brackets and hardware
See More

Carquest Premium – ABS Wheel Speed Sensor (Part No.ARC4344)

ABS Wheel Speed Sensor

from

$73.99
ABS Wheel Speed Sensor

Dorman – Coolant Housing/Water Outlet: With Housing (Part No.902-1074)

Coolant Housing/Water Outlet: With Housing

from

$36.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
See More

Dorman – Coolant Housing/Water Outlet: With Housing and Gasket, 90 Degree Neck Angle (Part No.902-1107)

Coolant Housing/Water Outlet: With Housing and Gasket, 90 Degree Neck Angle

from

$61.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
See More

APA/URO Parts – Expansion Tank Cap (Part No.G1040656905APA)

Expansion Tank Cap

from

$11.35
The APA/URO Expansion Tank Cap is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Motorcraft – Original Equipment Radiator Cap (Part No.G1010476698MTR)

Original Equipment Radiator Cap

from

$13.20
The Motorcraft Original Equipment Radiator Cap is an OES replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • Standard and safety vent radiator pressure caps available
  • Extensive coverage for most cars and trucks, as well as farm and construction equipment
  • Swivel-seal radiator caps are designed to provide increased durability and can be removed without damage to the rubber atmospheric seal
  • Zinc-plated to resist corrosion and rust
  • Pressure valve springs are made of stainless steel to maintain calibrated pressure throughout the service life
  • Rubber pressure valve gasket resists high temperatures and deterioration from coolant and additives
  • Pressure and vacuum relief features help extend radiator and hose life
  • Prevent accidental cap removal with positive low-pressure stop feature
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813145)

Radiator: With Transmission Oil Cooler

from

$294.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.431355)

Radiator: With Transmission Oil Cooler

from

$311.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
See More

Carquest Premium – Blower Motor: With Wheel (Part No.76900)

Blower Motor: With Wheel

from

$98.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
See More

Motorcraft – Motorcraft Blower Motor (Part No.R2031360444MTR)

Motorcraft Blower Motor

from

$158.69
Motorcraft electric blower motors are built in accordance with the requirements of the QS-9000 quality process.

Product Features:
  • They are built for specific vehicle applications for simple, bolt-up installations for shorter installation times
  • Motors are new and meet Ford fit, form and function requirements
  • To ensure proper operation, the motors are tested for current draw
See More

Motorcraft – A/C Pressure Switch (Part No.R1054836769MTR)

A/C Pressure Switch

from

$49.68
When servicing air conditioning systems, choose Motorcraft climate-control components. They offer quality at a great value and are the only climate-control components recommended by Ford Motor Company.

Product Features:
  • All parts meet original equipment requirements for fit, finish and durability
  • Specifically engineered for Ford and Lincoln vehicles
  • Durability tested to meet demanding original equipment service life specifications
  • Helps maintain original performance standards
See More

Factory Air – System Mounted Cycling Pressure Switch (Part No.36485)

System Mounted Cycling Pressure Switch

from

$18.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Color coded for easy identification
  • Zinc coated to resist corrosion
  • Vehicle specific applications
See More

Motorcraft – Motorcraft Thermostat (Part No.G4000479259MTR)

Motorcraft Thermostat

from

$69.10
The Motorcraft Thermostat is a direct fit OEM replacement that guarantees the same performance and quality provided by the vehicle manufacturer.

Product Features:
  • Heavy-duty quality for long life
  • Stainless steel or brass bridge and spring frame, channel-constructed for strength and rigidity
  • Stainless steel, tapered-end pistons with flexible elastomeric boots
  • Streamlined venturi nozzle for maximum coolant flow
  • Brass cover and guide for heat motor piston
  • Mounting flange designed to properly fit and seat the thermostat in the housing
  • Stainless steel spring offers precise operating compression
  • Heat motor in high-strength brass housing
  • Rulon seal for heat motor piston
  • Specially formulated expansive wax compound
See More

Motorcraft – Thermostat (Part No.G4000212055MTR)

Thermostat

from

$47.78
The Motorcraft Thermostat is a direct fit OEM replacement that guarantees the same performance and quality provided by the vehicle manufacturer.

Product Features:
  • Heavy-duty quality for long life
  • Stainless steel or brass bridge and spring frame, channel-constructed for strength and rigidity
  • Stainless steel, tapered-end pistons with flexible elastomeric boots
  • Streamlined venturi nozzle for maximum coolant flow
  • Brass cover and guide for heat motor piston
  • Mounting flange designed to properly fit and seat the thermostat in the housing
  • Stainless steel spring offers precise operating compression
  • Heat motor in high-strength brass housing
  • Rulon seal for heat motor piston
  • Specially formulated expansive wax compound
See More

2021 Ford F-250 Super Duty Cooling and Climate Controls

You count on your 2021 Ford F-250 Super Duty to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 37 Cooling and Climate Controls ranging in price from $3.89 to $592.99, you’re sure to find everything you need for your 2021 Ford F-250 Super Duty.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 7 different brands like Felpro, Carquest Premium, and Motorad UltraStats. 2021 Ford F-250 Super Duty Cooling and Climate Controls start as low as $3.89!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 1,570 extensive product reviews on 2021 Ford F-250 Super Duty Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Standard Thermostat: 195 Degrees with 4.3 stars and Radiator Drain Cocks with 4.4 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2021 Ford F-250 Super Duty below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2021 Ford F-250 Super Duty

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2021 Ford F-250 Super Duty running right for years to come. In our inventory you’ll find brands like Felpro, Carquest Premium, Motorad UltraStats, and even more.

Popular Motorad UltraStats Cooling and Climate Controls

You’ll find popular Motorad UltraStats brand products across Engine Cooling Parts. All are waiting to get your 2021 Ford F-250 Super Duty back on the road. Some of the top-rated Motorad UltraStats products in these categories are:
Thermostat: 180 Degrees
from $18.29
(1)
Thermostat: 180 Degrees
Thermostats

Top-Rated Felpro Cooling and Climate Controls


If Felpro are what you’re looking for, our inventory holds plenty. We stock Felpro brand Cooling and Climate Controls for your 2021 Ford F-250 Super Duty, and some of our most reviewed Felpro parts include:
Multi-Purpose O-Ring
from $9.99
(110)
Multi-Purpose O-Ring
Engine Coolant Pipe O-Rings
Engine Water Pump Gasket
from $6.79
(11)
Engine Water Pump Gasket
Water Pump Gaskets

FAQs for 2021 Ford F-250 Super Duty Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2021 Ford F-250 Super Duty?

Out of 37 Cooling and Climate Controls for the 2021 Ford F-250 Super Duty, the most popular in our inventory are:
High Flow Thermostat: 170 Degrees
from $14.29
(16)
High Flow Thermostat: 170 Degrees
Thermostats
Thermostat: 195 Degrees
from $18.29
This product is not rated
Thermostat: 195 Degrees
Thermostats
Standard Thermostat: 180 Degrees
from $15.79
(16)
Standard Thermostat: 180 Degrees
Thermostats

What are the top-rated 2021 Ford F-250 Super Duty Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2021 Ford F-250 Super Duty based on customer reviews/ratings are:
Standard Thermostat: 195 Degrees
from $15.79
(16)
Standard Thermostat: 195 Degrees
“Worked great.”
Radiator Drain Cocks
from $7.79
(7)
Radiator Drain Cocks
“Ford will tell you to buy a whole new radiator if you break the petcock. I installed this with success on my 2015 Focus ST. It is very close in size”
Engine Coolant Reservoir Cap
from $19.79
(7)
Engine Coolant Reservoir Cap
“Let’s see if this fixes the issue. A lot cheaper than what it could cost to fix the coolant leak!!”