Lexus RX350 Automatic Transmission Fluids

Your Lexus RX350 will be happy to know that the search for the right Automatic Transmission Fluids you’ve been looking for is over! Advance Auto Parts has 7 different Automatic Transmission Fluids for your vehicle, ready for shipping or in-store pick up. The best part is, our Lexus RX350 Automatic Transmission Fluids start from as little as $11.79.

When it comes to your Lexus RX350, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Automatic Transmission Fluids brands so you can shop with complete confidence. Some of our top Automatic Transmission Fluids brands are FRAM and Valvoline. We’re sure you will get the right product to keep that RX350 running for a long time.

We even have reviews of our OEM and aftermarket Automatic Transmission Fluids products to help you buy with confidence. Hear from other customers via the 3,244 reviews on parts for your Lexus RX350.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Automatic Transmission Fluids for your RX350, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 15 Lexus Automatic Transmission Fluids

Valvoline – ATF for Mercon®V Applications Conventional, 1 Quart (Part No.822345)

ATF for Mercon®V Applications Conventional, 1 Quart

from

$12.99
Valvoline ATF for MERCON®V Applications is a high-quality transmission fluid meeting and exceeding the requirements of the Ford Mercon V specification which covers most Ford passenger cars and light-duty trucks (except those specifying MERCON®SP, MERCON®LV or Type F fluids), including Lincoln and Mercury, as well as most pre-2006 GM vehicles and many imports. Recommended for use in the following applications: MERCON®V, MERCON®, DEXRON®-III, DEXRON®-II, Caterpillar TO-2, Allison C-4. Other applications include Power steering fluid where a DEXRON® or MERCON® fluid is recommended. Suitable to use in Nissan Matic D, Matic J and Matic K.

Product Features:
  • Formulated with premium base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Castrol – Transmax ATF Full Synthetic Multi-Vehicle Automatic Transmission Fluid (1 Quart) (Part No.152A76)

Transmax ATF Full Synthetic Multi-Vehicle Automatic Transmission Fluid (1 Quart)

from

$12.29
Automatic transmission fluid is a technologically advanced, low viscosity formulation specially designed to deliver performance and maximum fuel efficiency for modern automatic transmissions.

Product Features:
  • Full Synthetic, low viscosity formulation
  • OEM approved and licensed by Ford (MERCON® LV) and GM (DEXRON® -VI)
  • Low viscosity formula for maximum fuel efficiency in modern automatic transmissions
  • Enhanced friction durability for smooth transmission performance
  • Superior high temperature protection to effectively resist oxidation
  • Unsurpassed protection against copper corrosion
  • Industry Specifications and OEM Approvals: JASO-1A
  • Licensed and approved for use in: All GM vehicles (DEXRON®-VI, All previous DEXRON®); All Ford vehicles which specify Mercon® LV
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Castrol – Domestic Multi-vehicle (ATF) Automatic Transmission Fluid (1 Quart) (Part No.15ADFA)

Domestic Multi-vehicle (ATF) Automatic Transmission Fluid (1 Quart)

from

$7.99
Castrol® Transmax DEX/MERC includes enhanced friction durability for smooth transmission performance. Designed for use in older Ford and GM vehicles.

Product Features:
  • Enhanced friction durability for smooth transmission performance
  • Meets DEXRON®-III H requirements; also satisfies requirements of DEXRON®, DEXRON®-III, IIE, and II; do not use this ATF in applications calling for DEXRON®-VI
  • Meets MERCON® requirements; may also be used in power steering applications where MERCON® is required; use Castrol Type F ATF in applications calling for Type F
  • Do not use this ATF in applications calling for MERCON® V or MERCON® SP
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FRAM – Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon (Part No.F426-1G)

Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon

from

$33.99
FRAM DEXRON®-VI FULL SYNTHETIC ATF represents the latest technology in full  synthetic automatic transmission fluids. This product is designed for the newest  generation of highly efficient transmissions now being installed in most vehicles, and is  DEXRON®-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel  efficient choice for older models as well, such as those currently using DEXRON®-III. FRAM DEXRON®-VI FULL SYNTHETIC ATF is recommended for use in all GM  DEXRON® applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations.

Product Features:
  • Outstanding resistance to oxidative and thermal breakdown.
  • Exceptional low temperature fluidity.
  • Excellent anti-wear properties.
  • Excellent gear shift quality throughout service life.
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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FRAM – Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart (Part No.F426)

Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart

from

$11.79
FRAM DEXRON®-VI FULL SYNTHETIC ATF represents the latest technology in full  synthetic automatic transmission fluids. This product is designed for the newest  generation of highly efficient transmissions now being installed in most vehicles, and is  DEXRON®-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel  efficient choice for older models as well, such as those currently using DEXRON®-III. FRAM DEXRON®-VI FULL SYNTHETIC ATF is recommended for use in all GM  DEXRON® applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations.

Product Features:
  • Outstanding resistance to oxidative and thermal breakdown.
  • Exceptional low temperature fluidity.
  • Excellent anti-wear properties.
  • Excellent gear shift quality throughout service life.
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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FRAM – Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 1 Quart (Part No.F420)

Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 1 Quart

from

$8.79
FRAM DEX III/MERC ATF is formulated for older model Ford and General Motors  vehicles requiring MERCON®, DEXRON-I®, DEXRON-II® and DEXRON-III®. It is also  recommended for transmissions, power steering systems, and hydraulic systems  requiring a DEXRONIII® or Caterpillar TO-2 fluid. FRAM DEX III/MERC ATF may also  be used in compressors, pumps, and hydraulic systems. FRAM DEX III-H/M ATF is  recommended for use in all transmissions, hydraulic systems, and power steering units  manufactured by American, European, Korean, Japanese and other manufactures from  around the world specifying DEXRON®III H/Mercon® and earlier DEXRON®/Mercon® type transmission fluids.

Product Features:
  • Good foam and corrosion prevention
  • Safe for seals
  • Promotes smooth shifting
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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FRAM – Full Synthetic Global Multi-Vehicle Automatic Transmission Fluid: 1 Quart (Part No.F470)

Full Synthetic Global Multi-Vehicle Automatic Transmission Fluid: 1 Quart

from

$11.49
FRAM Global ATF is formulated to meet the fluid needs of a broad range of automatic  transmissions. Using advanced additive technology and base fluids, it is suitable for service fill of  many transmissions manufactured by North American, Asian, and European OEMs. FRAM  Global ATF provides oxidation and thermal stability, friction control, load-carrying ability, corrosion  and wear protection. It helps protect against the formation of sludge, varnish and foam. FRAM Global ATF has exceptional low temperature flow properties and enhanced protection  against viscosity breakdown at high temperatures. It also has exceptional oxidation and thermal  stability, resulting in maximum service life.

Product Features:
  • Maintains friction control for smooth shift action and protection against shudder
  • Retains high temperature viscosity resulting in maximum oil film thickness and  excellent wear
  • Controls sludge, corrosion, and wear of gears
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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FRAM – Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 1 Gallon (Part No.F420-1G)

Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 1 Gallon

from

$28.99
FRAM DEX III/MERC ATF is formulated for older model Ford and General Motors  vehicles requiring MERCON®, DEXRON-I®, DEXRON-II® and DEXRON-III®. It is also  recommended for transmissions, power steering systems, and hydraulic systems  requiring a DEXRONIII® or Caterpillar TO-2 fluid. FRAM DEX III/MERC ATF may also  be used in compressors, pumps, and hydraulic systems. FRAM DEX III-H/M ATF is  recommended for use in all transmissions, hydraulic systems, and power steering units  manufactured by American, European, Korean, Japanese and other manufactures from  around the world specifying DEXRON®III H/Mercon® and earlier DEXRON®/Mercon® type transmission fluids.

Product Features:
  • Good foam and corrosion prevention
  • Safe for seals
  • Promotes smooth shifting
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.30040096-75000C)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
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FRAM – Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 5 Gallon (Part No.F420-5)

Dexron III / Mercon Multi-Vehicle Automatic Transmission Fluid: 5 Gallon

from

$96.99
FRAM DEX III/MERC ATF is formulated for older model Ford and General Motors  vehicles requiring MERCON®, DEXRON-I®, DEXRON-II® and DEXRON-III®. It is also  recommended for transmissions, power steering systems, and hydraulic systems  requiring a DEXRONIII® or Caterpillar TO-2 fluid. FRAM DEX III/MERC ATF may also  be used in compressors, pumps, and hydraulic systems. FRAM DEX III-H/M ATF is  recommended for use in all transmissions, hydraulic systems, and power steering units  manufactured by American, European, Korean, Japanese and other manufactures from  around the world specifying DEXRON®III H/Mercon® and earlier DEXRON®/Mercon® type transmission fluids.

Product Features:
  • Good foam and corrosion prevention
  • Safe for seals
  • Promotes smooth shifting
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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Castrol – Transmax ATF High Mileage Automatic Transmission Fluid: 1 Gallon (Part No.1599F1)

Transmax ATF High Mileage Automatic Transmission Fluid: 1 Gallon

from

$49.99
Castrol Transmax High Mileage is specially formulated for transmissions with over 75,000 miles to deliver superior performance for maximum transmission life. It features additional seal conditioners to help stop leaks and cleaning agents to reduce varnish and deposit formation. It also protects against clutch wear and restores smooth shifting and can be used in a wide variety of specifications including DEXRON®-IIIH, MERCON® and JASO-1A.

Product Features:
  • Additional seal conditioners help stop leaks.
  • Extra cleaning agents reduce varnish and sludge formation.
  • Protects against clutch wear and restores smooth shifting.
  • Recommended for use in new & older vehicles that require:
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Idemitsu – Type TLS-LV Automatic Transmission Fluid – 1 qt (Part No.10114-042B)

Type TLS-LV Automatic Transmission Fluid - 1 qt

from

$12.79
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Castrol – BP Petroleum Autran Syn 295 Synthetic Automatic Transmission Fluid, 1 Gallon (Part No.709732)

BP Petroleum Autran Syn 295 Synthetic Automatic Transmission Fluid, 1 Gallon

from

$71.99
Full-Synthetic; Heavy Duty Automatic Transmission; BP Autran Syn-295 is a full-synthetic, heavy duty automatic transmission fluid approved for use under Allison TES-295. It is formulated to maintain its stability, even under the most severe operating conditions.

Product Features:
  • Formulated with high viscosity index 100% synthetic base fluids and specific additives in order to exceed Allison requirements and provide outstanding wear protection
  • Keeps transmissions cooler, offering excellent shear stability, low oxidation and high heat capacity
  • Provides superior high/low temperature performance due to high VI synthetic base fluids and has excellent corrosion and foaming resistance
  • BP Autran Syn-295 also has an Allison TES-468 approval for use in Allison Hybrid Electric Drive Transmissions
  • Other OEM approvals include Allison C-4, Voith and ZF transmissions
  • BP Autran Syn-295 is an ideal transmission fluid for light duty application vehicles, such as:
  • Inter/intra-city buses & school buses
  • Emergency vehicles
  • Delivery trucks & vans
  • Recreational vehicles & motor homes
  • Refuse vehicles
  • On/off-highway vehicles
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Castrol – Transmax ATF & CVT Universal (Part No.15E0C8)

Transmax ATF & CVT Universal

from

$25.99
Transmax ATF & CVT Universal

ATP – Auto Trans Fluid (Part No.AT-216)

Auto Trans Fluid

from

$22.99
Product Features:
  • Fully Synthetic
  • Advance transmission protection from standard to sever duty
  • Resist thermal breakdown, oxidation, varnish and sludge
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FAQs for Lexus RX350 Automatic Transmission Fluids

What are the most popular Automatic Transmission Fluids for the Lexus RX350?

With 5 brands you can trust, our most popular Automatic Transmission Fluids for the Lexus RX350 are:
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
from $33.99
This product is not rated
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
Automatic Transmission Fluids
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart
from $11.79
This product is not rated
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart
Automatic Transmission Fluids
ATF for Mercon®V Applications Conventional, 1 Quart
from $12.99
(120)
ATF for Mercon®V Applications Conventional, 1 Quart
Automatic Transmission Fluids