2022 Ford E-350 Super Duty Drivetrains

Essential 2022 Ford E-350 Super Duty Drivetrains

Neapco – Universal Joint (Part No.2-0052)

Universal Joint

from

$15.59
Universal Joint
See More

Omix – U-Joint Kit (Part No.5-806X)

U-Joint Kit

from

$124.99
Are your U-joints making noise? Or has one broken? When they do break, they usually damage the axle shafts or driveshafts too. That’s a lot of unnecessary work and expense. U-joint replacement is a routine maintenance chore. Omix-ADA offers high quality r

Product Features:
  • Front
  • OE Style
  • Direct Fit
  • Limited 5 Year Warranty
See More

Timken – Driveshaft Support with Bearing (Part No.K1030195244TIM)

Driveshaft Support with Bearing

from

$57.17
The Timken Driveshaft Support is an ideal high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

SKF – Driveshaft Support (Part No.K10301069521SKF)

Driveshaft Support

from

$89.23
Driveshaft Support

Motive Gear – Differential Pinion Seal (Part No.9316)

Differential Pinion Seal

from

$16.49
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

Driveworks – Differential Pinion Seal (Part No.S-100715-V)

Differential Pinion Seal

from

$16.99
Product Features:
  • Brand may vary by location
See More

Spicer – Universal Joint (Part No.5-160X)

Universal Joint

from

$40.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.
See More

Spicer – Universal Joint (Part No.5-178X)

Universal Joint

from

$42.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.
See More

Valvoline – ATF for Mercon®V Applications Conventional, 1 Quart (Part No.822345)

ATF for Mercon®V Applications Conventional, 1 Quart

from

$12.99
Valvoline ATF for MERCON®V Applications is a high-quality transmission fluid meeting and exceeding the requirements of the Ford Mercon V specification which covers most Ford passenger cars and light-duty trucks (except those specifying MERCON®SP, MERCON®LV or Type F fluids), including Lincoln and Mercury, as well as most pre-2006 GM vehicles and many imports. Recommended for use in the following applications: MERCON®V, MERCON®, DEXRON®-III, DEXRON®-II, Caterpillar TO-2, Allison C-4. Other applications include Power steering fluid where a DEXRON® or MERCON® fluid is recommended. Suitable to use in Nissan Matic D, Matic J and Matic K.

Product Features:
  • Formulated with premium base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Yukon Gear – Redline Synthetic "Shock Proof" Oil With Positraction Additive – 4 Quarts (Part No.15005)

Redline Synthetic "Shock Proof" Oil With Positraction Additive - 4 Quarts

from

$148.99
Redline Synthetic “Shock Proof” Oil with positraction Additive. 4 Quarts.

Product Features:
  • Includes four quarts of Redline Shockproof oil and one 4oz bottle of Yukon positraction additive
See More

Driveworks – Taper Bearing Cup (Part No.S-15245)

Taper Bearing Cup

from

$5.99
Value-priced bearing meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Bearings (Part No.15101)

Bearings

from

$16.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Yukon Gear – Spindle Nut For Dana 60 & 70, 1.940" I.D., With Plastic Ring (Part No.33486)

Spindle Nut For Dana 60 & 70, 1.940" I.D., With Plastic Ring

from

$26.99
Spindle nut for Dana 60 & 70, 1.940″ I.D., with plastic ring. This replaces Spicer part number 39695.

Product Features:
  • Spindle nut
  • Fits Dana Spicer 60 and 70
  • 1.940″ I.D.
  • Has plastic inner ring
See More

Yukon Gear – Spindle Nut For Dana 70, 1.940" I.D., 6 Slots (Part No.33479)

Spindle Nut For Dana 70, 1.940" I.D., 6 Slots

from

$40.99
Spindle nut for Dana 70, 1.940″ I.D., 6 slots. This replaces Spicer part number 33732.

Product Features:
  • Spindle nut for Dana Spicer 70, 70U and 70HD
  • 1.940″ I.D.
  • 6 slots
See More

Dorman – Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (sold by each) (Part No.615-072)

Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (sold by each)

from

$3.99
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

National – Bearings (Part No.HM803149)

Bearings

from

$36.49
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

National – Bearings (Part No.HM803146)

Bearings

from

$47.49
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Pro-King – Differential Bearing Cup (Part No.764A256)

Differential Bearing Cup

from

$18.99
Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

Product Features:
  • All products are designed to meet or exceed OE quality, form, fit and funtion.
See More

Dorman – Spindle Nut (Part No.K1002831714DOR)

Spindle Nut

from

$42.79
Spindle Nut

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$20.29
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6056)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$22.79
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to AUTOCAR 84-88; CHECKER 55-82; CHEV 60-12; DODGE 57-02; FORD 55-10; GMC 63-07; INTL 57-02; ISUZU 96-01; KW 81-18; MACK 80-90; MAZDA 87-94; MITS 87-09; OLDS 90-01; PLYM 80-83; PTRB 65-83; WHGM 88-95; WHIT 81-88;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1955-2018
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.3780 INCH / 35 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • COMPLETE MOUNT
See More

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6038)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$34.49
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to AUTOCAR 84-88; CHEV 60-02; DODGE 57-02; FORD 55-07; GMC 63-02; INTL 57-02; KW 81-18; MACK 80-83; PTRB 65-83; WHGM 88-95; WHIT 81-88;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1955-2018
  • Weight approx: 4 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.48 INCH / 63 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • NOT PICTURED: TWO DUST SHIELDS
See More

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6053)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$39.49
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to CHEV 60-02; DODGE 64-66; FORD 75-15; GMC 60-02;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1960-2015
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • NO STUDS
See More

Driveworks – Drive Shaft Center Support (Part No.S-HB-88508-A)

Drive Shaft Center Support

from

$29.49
Drive Shaft Center Support

2022 Ford E-350 Super Duty Drivetrains

You count on your 2022 Ford E-350 Super Duty to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Drivetrains. With 25 Drivetrains ranging in price from $3.49 to $83.99, you’re sure to find everything you need for your 2022 Ford E-350 Super Duty.

Brands matter. If you want to shop a specific Drivetrains brand, we stock 11 different brands like Valvoline, Moog, and Driveworks. 2022 Ford E-350 Super Duty Drivetrains start as low as $3.49!

One of the best ways to find top quality OEM or aftermarket Drivetrains is by asking professionals. Short of that, you can shop with confidence thanks to our 661 extensive product reviews on 2022 Ford E-350 Super Duty Drivetrains. Some of the top-rated Drivetrains products we carry are Greaseable Premium Universal Joint with 4.0 stars and Greaseable Premium Universal Joint with 4.7 stars.

Did we mention you can order your Drivetrains from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Drivetrains inventory for your 2022 Ford E-350 Super Duty below to get started!

Top-Rated Drivetrains Brands For Your 2022 Ford E-350 Super Duty

Trusted Drivetrains OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2022 Ford E-350 Super Duty running right for years to come. In our inventory you’ll find brands like Valvoline, Moog, Driveworks, and even more.

Popular Dorman Drivetrains

You’ll find popular Dorman brand products across Spindles and Drive Shafts and Axles. All are waiting to get your 2022 Ford E-350 Super Duty back on the road. Some of the top-rated Dorman products in these categories are:
Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In.
from $3.49
(3)
Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In.
Spindle Lock Nuts
Driveshaft Flange Bolts
from $20.29
(1)
Driveshaft Flange Bolts
Drive Shaft Support Bolts

FAQs for 2022 Ford E-350 Super Duty Drivetrains

What are the most purchased Drivetrains for the 2022 Ford E-350 Super Duty?

Out of 25 Drivetrains for the 2022 Ford E-350 Super Duty, the most popular in our inventory are:
Greaseable Super Strength Universal Joint
from $55.99
(39)
Greaseable Super Strength Universal Joint
U-Joints
Greaseable Super Strength Universal Joint
from $36.99
(41)
Greaseable Super Strength Universal Joint
U-Joints
Universal Joint
from $15.99
(28)
Universal Joint
U-Joints

What are the top-rated 2022 Ford E-350 Super Duty Drivetrains?

Top-rated Drivetrains for your 2022 Ford E-350 Super Duty based on customer reviews/ratings are:
Greaseable Premium Universal Joint
from $19.99
(31)
Greaseable Premium Universal Joint
“Greaseable with life time warranty”
Greaseable Premium Universal Joint
from $28.99
(20)
Greaseable Premium Universal Joint
“Fit perfect no issues”
Bearings
from $16.99
(17)
Bearings
“Great bearing”