2022 Ford E-350 Super Duty Drive Shafts and Axles

Keep Your 2022 Ford E-350 Super Duty in Top Shape with Quality Drive Shafts and Axles

Whether you’re repairing or upgrading your Drive Shafts and Axle, using high-quality parts is key to keeping your 2022 Ford E-350 Super Duty looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Center Support Bearings, Drive Shaft Bearings, and Drive Shaft Support Bolts. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Drive Shafts and Axles from Trusted Brands

Looking for a reliable Drive Shafts and Axle? We’ve got you covered with options from brands you know and trust like Dorman, Spicer, and National. For example, Dorman Drive Shafts and Axles start at just $22.49 with an average 4.2 star rating. Spicer and National offer similar pricing and quality, backed by strong customer feedback. With over 19 reviews and a solid 5 star average, you can shop with confidence knowing other Ford E-350 Super Duty owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2022 Ford E-350 Super Duty Drive Shafts and Axle at Advance Auto Parts is around $29.09, with a range that starts at $9.99 and goes up to $45.99. With 5 options in stock from 4 trusted brands, finding the right fit is easy. Popular picks like Bearings, Center Support Bearing Motor Mount: Center, 1 Piece, and Axle Flange Gasket Kit start at just $9.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Drive Shafts and Axle, don’t forget to check out other key components like Differentials and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2022 Ford E-350 Super Duty in peak condition, inside and out.

Essential 2022 Ford E-350 Super Duty Drive Shafts and Axles

Dorman – Axle Flange Gasket Kit (Part No.926-880)

Axle Flange Gasket Kit

from

$27.99
Ensure a leak-free repair when servicing axle bearings or parking brake shoes. This axle shaft flange seal is a direct replacement for the original gasket and should be replaced every time work is performed at the axle flange.

Product Features:


    Product Features:
    • Ideal replacement – this axle shaft flange seal directly replaces the original gasket without having to visit the dealer
    • Required for routine service – this gasket should be replaced every time work is performed at the axle flange
    • Durable construction – this axle shaft flange gasket is made of tough, durable materials for leak-free performance
    • Quality tested – this flange gasket has been designed and tested for a guaranteed fit
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National – Bearings (Part No.15245)

Bearings

from

$9.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6053)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$38.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to CHEV 60-02; DODGE 64-66; FORD 75-15; GMC 60-02;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1960-2015
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • NO STUDS
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6038)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$40.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to AUTOCAR 84-88; CHEV 60-02; DODGE 57-02; FORD 55-07; GMC 63-02; INTL 57-02; KW 81-18; MACK 80-83; PTRB 65-83; WHGM 88-95; WHIT 81-88;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1955-2018
  • Weight approx: 4 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.48 INCH / 63 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • NOT PICTURED: TWO DUST SHIELDS
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6056)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$21.49
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to AUTOCAR 84-88; CHECKER 55-82; CHEV 60-12; DODGE 57-02; FORD 55-10; GMC 63-07; INTL 57-02; ISUZU 96-01; KW 81-18; MACK 80-90; MAZDA 87-94; MITS 87-09; OLDS 90-01; PLYM 80-83; PTRB 65-83; WHGM 88-95; WHIT 81-88;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1955-2018
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.3780 INCH / 35 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • COMPLETE MOUNT
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Driveworks – Ball Bearing (Part No.S-HB-88107-A)

Ball Bearing

from

$19.99
Value-priced bearing meets all cataloged application requirements.
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Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$22.49
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Driveworks – Universal Joint (Part No.DW-331BL)

Universal Joint

from

$15.99
Driveworks Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. Driveworks Universal Joints are constructed from quality materials for extended durability. Driveworks Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:
  • The cross is hot forged for the higher torque and horsepower
  • The bearing cups are made by cold forging, having higher strength and better rigidity
  • Bearing cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
  • Lubrication grooves are designed to ensure grease penetration to entire journal and needle bearings
  • Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
  • Snap rings are held to strict tolerances to ensure proper cup position and retention
  • Nitrile rubber seals to optimize grease retention and reduce contamination
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Spicer – Universal Joint (Part No.5-1350X)

Universal Joint

from

$45.99
You expect a lot from your vehicle, and Spicer Life Series (SPL) universal joints deliver. SPL universal joints consistently outperform competitors, so you can hit the road or trail with confidence. Check out the difference that SPL universal joints can make in your vehicle, and make sure you are getting the longer life, increased bearing capacity and lower maintenance costs that Spicer Life Series (SPL) can provide.
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Spicer – Universal Joint (Part No.5-1350-1X)

Universal Joint

from

$49.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.
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Spicer – Universal Joint, Greaseable 1350 Series (Part No.5-178X)

Universal Joint, Greaseable 1350 Series

from

$44.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

Product Features:
  • OE engineering and field tested experience is why the Spicer brand is the most trusted in the industry.
  • Forged with high-quality steel, these u-joints are heat treated and case-hardened with precision to specific levels, ensuring optimal strength and durability.
  • The process of precision grinding the seal and bearing surfaces helps to improve the life of the seal and bearing.
  • Zerk allows for lubricating at regular intervals to help extend the life of the part.
See More

Spicer – Universal Joint, Greaseable 1410 Series (Part No.5-160X)

Universal Joint, Greaseable 1410 Series

from

$45.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

Product Features:
  • OE engineering and field tested experience is why the Spicer brand is the most trusted in the industry.
  • Forged with high-quality steel, these u-joints are heat treated and case-hardened with precision to specific levels, ensuring optimal strength and durability.
  • The process of precision grinding the seal and bearing surfaces helps to improve the life of the seal and bearing.
  • Zerk allows for lubricating at regular intervals to help extend the life of the part.
See More

Most Popular Center Support Bearing for 2022 Ford E-350 Super Duties

Enhance your 2022 Ford E-350 Super Duty with this popular Center Support Bearing we have in stock, for $38.99.

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6053)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$38.99
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to CHEV 60-02; DODGE 64-66; FORD 75-15; GMC 60-02;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1960-2015
  • Weight approx: 3 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.28 INCH / 58 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • NO STUDS
See More

Best-Selling 2022 Ford E-350 Super Duty Drive Shaft Bearing

Upgrade your E-350 Super Duty with our best-selling Drive Shaft Bearing with a 4.5 Starts rating across 8 reviews.

National – Bearings (Part No.15245)

Bearings

from

$9.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Top-Quality Drive Shaft Support Bolts for 2022 Ford E-350 Super Duties

Choose a high-quality OEM or aftermarket Drive Shaft Support Bolt for Ford E-350 Super Duties and enjoy top-notch performance from $22.49.

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$22.49
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Our Top Pick for a 2022 Ford E-350 Super Duty Axle Shaft Universal Joint

Invest in a durable Axle Shaft Universal Joint for your 2022 Ford, knowing you’re getting trusted brands and expert craftsmanship.

Spicer – Universal Joint, Greaseable 1410 Series (Part No.5-160X)

Universal Joint, Greaseable 1410 Series

from

$45.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

Product Features:
  • OE engineering and field tested experience is why the Spicer brand is the most trusted in the industry.
  • Forged with high-quality steel, these u-joints are heat treated and case-hardened with precision to specific levels, ensuring optimal strength and durability.
  • The process of precision grinding the seal and bearing surfaces helps to improve the life of the seal and bearing.
  • Zerk allows for lubricating at regular intervals to help extend the life of the part.
See More

Our Axle Flange Gaskets for 2022 Ford E-350 Super Duties

Make a smart move for your 2022 Ford E-350 Super Duty with our Axle Flange Gasket for $27.99.

Dorman – Axle Flange Gasket Kit (Part No.926-880)

Axle Flange Gasket Kit

from

$27.99
Ensure a leak-free repair when servicing axle bearings or parking brake shoes. This axle shaft flange seal is a direct replacement for the original gasket and should be replaced every time work is performed at the axle flange.

Product Features:


Product Features:
  • Ideal replacement – this axle shaft flange seal directly replaces the original gasket without having to visit the dealer
  • Required for routine service – this gasket should be replaced every time work is performed at the axle flange
  • Durable construction – this axle shaft flange gasket is made of tough, durable materials for leak-free performance
  • Quality tested – this flange gasket has been designed and tested for a guaranteed fit
See More

Top-Rated Drive Shafts and Axle Brands For Your 2022 Ford E-350 Super Duty

When it comes to finding the perfect Drive Shafts and Axle for your 2022 Ford E-350 Super Duty, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 4 trusted brands. We carry the most popular Drive Shafts and Axle brands including Spicer, National, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $9.99. Purchasing a Drive Shafts and Axle from us here at Advance Auto Parts is a smart move for both you and your 2022 Ford E-350 Super Duty, providing peace of mind with parts that meet or exceed OEM standards.

Popular Spicer 2022 Ford E-350 Super Duty Drive Shafts and Axles

If you’re looking for a top-quality Drive Shafts and Axle for your 2022 Ford E-350 Super Duty, Advance Auto Parts has exactly what you need with our selection of Spicer Drive Shafts and Axles. We have 1 Spicer Drive Shafts and Axles in stock for this fitment, all known for their durability and precision fit. With prices starting at just $45.99, you’ll find the perfect Drive Shafts and Axle for your needs and budget. Spicer Drive Shafts and Axles for the 2022 Ford E-350 Super Duty come highly rated, with over 10 customer reviews and an impressive average rating of 4.6 stars. Choosing a Spicer Drive Shafts and Axle from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Universal Joint, Greaseable 1410 Series
from $45.99
(10)
Universal Joint, Greaseable 1410 Series
“Went in perfect”

Top-Quality National 2022 Ford E-350 Super Duty Drive Shafts and Axles

For those in search of a high-quality Drive Shafts and Axle for their 2022 Ford E-350 Super Duty, Advance Auto Parts offers a great selection of National Drive Shafts and Axles. With 1 National Drive Shafts and Axles in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Drive Shafts and Axles start at just $9.99, giving you a range of options to suit your budget. Backed by over 8 customer ratings and an average rating of 4.3 stars, National Drive Shafts and Axles provide both reliability and excellent performance. Choosing a National Drive Shafts and Axle from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
Bearings
from $9.99
(8)
Bearings
“It fits in Ford. I drove only few hundred miles can’t say much about it.”

FAQs for 2022 Ford E-350 Super Duty Drive Shafts and Axles

What are the best-selling Drive Shafts and Axles for 2022 Ford E-350 Super Duties?

Out of 5 Drive Shafts and Axles that fit 2022 Ford E-350 Super Duties, the following parts are the top sellers:

What’s the price range for 2022 Ford E-350 Super Duty Drive Shafts and Axles?

The prices of Drive Shafts and Axles for the 2022 Ford E-350 Super Duty range from $9.99 up to $45.99 for the most premium parts.

What is the average price of a Drive Shafts and Axle for a 2022 Ford E-350 Super Duty?

The average price for Drive Shafts and Axles for the 2022 Ford E-350 Super Duty is $29.09. Keep in mind the variety of part types within our Drive Shafts and Axle category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drive Shafts and Axles for other Ford E-350 Super Duty model years?

Yes, we carry Drive Shafts and Axles for 23 model years of Ford E-350 Super Duties between 2000 and 2025. The following model years are the most popular for Drive Shafts and Axle purchases: 2021, 2019, 2018, 2017, 2016, 2015, 2014, 2013, and 2012.

What are the cheapest Drive Shafts and Axles for my 2022 Ford E-350 Super Duty?

The cheapest 2022 Ford E-350 Super Duty Drive Shafts and Axles we carry are:

Does Advance Auto Parts sell Drive Shafts and Axles for any other 2022 Ford models?

What are the top-rated Drive Shafts and Axles that fit the 2022 Ford E-350 Super Duty?

Based on 19 reviews by customers, our 2022 Ford E-350 Super Duty Drive Shafts and Axles have an average customer rating of 5 stars. These are the highest-rated categories of Drive Shafts and Axles for the 2022 Ford E-350 Super Duty and their top-rated products:

What types of Drive Shafts and Axles do you sell for my 2022 Ford E-350 Super Duty?

As of 11/2/25, these are some of the most in-demand types of Drive Shafts and Axles for a 2022 Ford E-350 Super Duty:

Can I get help with 2022 Ford E-350 Super Duty Drive Shafts and Axle orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Drive Shafts and Axles and more.

What is your return policy for Ford E-350 Super Duty Drive Shafts and Axles?

Advance Auto Parts keeps returns simple. For new Ford E-350 Super Duty Drive Shafts and Axles and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.