2022 Ford E-350 Super Duty Differential Oils

Differential oil is essential for keeping your 2022 Ford E-350 Super Duty running smoothly, as it lubricates the gears that help your vehicle turn and navigate those tight corners. Regular maintenance is key, so be sure to check the differential oil level and condition every 30,000 to 50,000 miles or as specified in your owner’s manual. If you notice any unusual noises—like grinding or whining sounds emanating from the rear end—or if you see oil leaks under your vehicle, it might be time to give that differential oil some attention. Ensuring the right oil levels and quality not only prolongs the life of your differential but also enhances your driving experience, giving you peace of mind when you hit the road.

Essential Differential Oil Maintenance for Your 2022 Ford E-350 Super Duty

When it comes to maintaining your 2022 Ford E-350 Super Duty, don’t overlook the importance of differential oil—it plays a crucial role in keeping your vehicle’s drivetrain functioning smoothly. Regularly changing and upgrading your differential oil can improve your truck’s performance, enhance fuel efficiency, and extend the life of your components. At Advance Auto Parts, we’ve got a wide range of quality differential oils from trusted brands that you can count on to meet OEM specifications and keep your rig running like new. By choosing top-notch products from us, you can rest assured that you’re giving your Super Duty the care it deserves while also getting the best bang for your buck—no one wants to cut corners when it comes to the parts that do the heavy lifting!

Cost of Differential Oil for Your 2022 Ford E-350 Super Duty

At Advance Auto Parts, we know that when it comes to keeping your vehicle running smoothly, choosing the right differential oil is crucial, and we’ve got a great selection to fit your needs and budget. You’ll find a range of brands that cater to your DIY spirit, with prices spanning from just $14.49 to $69.99, averaging around $40.39. Whether you’re looking for a high-performance option to tackle tough terrains or a reliable pick for everyday driving, we’ve got you covered with quality products that won’t break the bank.

Complete Your 2022 Ford E-350 Super Duty Differential Oil Job with the Right Tools and Parts

When you’re tackling the maintenance or repair of your differential oil, you might want to grab a few related products to make your job easier and more efficient. Aside from the appropriate differential oil itself, having a good quality gasket or sealant on hand will help ensure a leak-free installation. Don’t forget about a reliable oil pump or fluid transfer tool to make pouring the oil smoother—nobody likes the mess that can come from a spill! A wrench set is usually necessary for removing the differential cover bolts, and if you’re dealing with stubborn fasteners, a breaker bar can come in handy. As always, safety should be your top priority; make sure to wear gloves to protect your hands from oil and sharp edges, and goggles to shield against any splashes while you’re working. Taking these precautions can help you focus on getting the job done right!

Differential Oils for Your 2022 Ford E-350 Super Duty

Valvoline – DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.822405)

DEXRON - VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.49
Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, and Allison C-4.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon (Part No.887344)

SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon

from

$69.99
Valvoline SAE 75W-140 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our formulation provides exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity and wear resistance, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. It’s recommended for conventional rear axles and transmissions requiring EP gear lubes under high speed, high load, high torque and high horsepower conditions.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -22F to 390F degrees
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5
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Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

from

$18.99
We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:
  • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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FAQs for 2022 Ford E-350 Super Duty Differential Oils

Which Differential Oils are the top sellers for the 2022 Ford E-350 Super Duty?

Out of 3 Differential Oils that fit 2022 Ford E-350 Super Duties, the following parts are the top sellers:
Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart
from $18.99
This product is not rated
Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart
Differential Oil

How can I make sure that a part will be compatible with my 2022 Ford E-350 Super Duty?

Our Ford E-350 Super Duty aftermarket and OEM parts are designed specifically for the 2022 model. You can always find your specific fitment and compatibility for your 2022 Ford on an individual product page.

What is the price range for 2022 Ford E-350 Super Duty Differential Oils?

The range of prices of Differential Oils for the 2022 Ford E-350 Super Duty goes from $14.49 up to $69.99 for the most premium parts.

What is the average price of 2022 Ford E-350 Super Duty Differential Oils?

2022 Ford E-350 Super Duty Differential Oils average $34.49 for our selection of OEM and aftermarket parts.

Does Advance Auto Parts sell Differential Oils for other Ford E-350 Super Duty model years?

Yes, we currently stock Differential Oils for 23 model years of Ford E-350 Super Duties, from 2000 to 2025. Model years 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, and 2011 are the most popular for Differential Oils purchases.

Can I get help with 2022 Ford E-350 Super Duty Differential Oils orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Differential Oils and more.

What is your return policy for Ford E-350 Super Duty Differential Oils?

Advance Auto Parts keeps returns simple. For new Ford E-350 Super Duty Differential Oils and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.