2021 Ford F-350 Super Duty Engine Cooling Parts
Keep Your 2021 Ford F-350 Super Duty in Top Shape with Quality Engine Cooling Parts
Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2021 Ford F-350 Super Duty looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Radiators, Thermostat and Water Outlet Gaskets, and Water Pumps. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.
Top-Rated Engine Cooling Parts from Trusted Brands
Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium, FELPRO, and Dorman. For example, Carquest Premium Engine Cooling Parts start at just $12.99 with an average 4.4 star rating. FELPRO and Dorman offer similar pricing and quality, backed by strong customer feedback. With over 1,555 reviews and a solid 4 star average, you can shop with confidence knowing other Ford F-350 Super Duty owners approve.
Competitive Prices and Extensive Inventory
The average price for a 2021 Ford F-350 Super Duty Engine Cooling Part at Advance Auto Parts is around $125.51, with a range that starts at $2.99 and goes up to $2,150.99. With 27 options in stock from 7 trusted brands, finding the right fit is easy. Popular picks like High Flow Thermostat: 170 Degrees, UltraStat Thermostat: 195 Degrees, and Standard Thermostat: 180 Degrees start at just $14.99 and offer a great balance of form and function.
Explore Related Parts
While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blend Doors and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2021 Ford F-350 Super Duty in peak condition, inside and out.
Find Your Specific 2021 Ford F-350 Super Duty Engine Cooling Parts
Looking for the perfect Engine Cooling Part for your 2021 Ford F-350 Super Duty? You’re in the right place. Below, you’ll find links to various types of Engine Cooling Parts that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Engine Cooling Parts, ensuring durability and a precise fit for your Ford F-350 Super Duty. Whether you’re driving a 2021 model or another popular model year like
2013,
2014,
2015,
2016,
2017,
2018,
2019,
2020, and
2022, we’ve got you covered. Purchasing Engine Cooling Parts from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Engine Cooling Parts that fit your vehicle.
Essential 2021 Ford F-350 Super Duty Engine Cooling Parts
Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 185 Degrees (Part No.5004KT)
from
$40.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Product Features:
Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 192 Degrees (Part No.902-685)
from
$32.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
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Product Features:
- Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
- Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
- Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
- Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.433837)
from
$465.99
A global leader in the manufacture and distribution of aftermarket cooling products for automotive, heavy truck, and industrial applications. Specialized in the production of OE-quality Radiators, Condensers, and Charge Air Coolers for US and international markets, covering over 10,000 part numbers worldwide. Reach Cooling is headquartered in Miami, Florida, with additional distribution centers in Los Angeles, California and a manufacturing plant in Shanghai, China.
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Product Features:
- Radiators are the foundation of any engine cooling system. Tasked with preventing the vehicle from overheating, the radiator is vital to keeping vehicles up and running. We design and manufacture all our radiators to meet or even exceed Original Equipme
- Thermal expansion cuts allow for longer life and reduces failure rates by allowing improved core expansion and contraction during normal heat cycles.
- Our B-Type tubes feature central reinforcement to provide greater tolerance to pressure. Stronger tube design means drastically reduced probability of tube failure.
- We use longer header tabs for increased pressure resistance. This reduces the potential for tank to header leaks.
- Our deep extrusion header provides a stronger tube to header joint which is more resistant to the effects of vibration and thermal tube expansion, virtually eliminating tube to header leaks.
- Our fin edges are folded for increased stability and heat disbursement properties.
- Our included “multi-fit” attachments allow one radiator to cover multiple vehicle applications without sacrificing OE fit. This results in wider vehicle coverage with substantially less inventory.
Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813717)
from
$604.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.
Product Features:
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Product Features:
- Thermal tested under real-life temperature simulations
- High tensile strength aluminum for maximum crimp strength
- Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
- Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35610-1)
from
$6.49
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered and manufactured specifically for the repair environment
- Unsurpassed quality you can trust
- Validated for fit, form, and function
Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35702)
from
$4.79
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design to ensure a perfect fit
- Engineered and manufactured specifically for the repair environment
- Unsurpassed quality you can trust
- Validated for fit, form, and function
Dorman – Help – Upper and Lower Coolant Hose Seal (OE Fix) (Part No.47450)
from
$18.49
Certain Ford vehicles use radiator hoses that employ a connection sealed with an O-ring. Through age, heat cycling and normal wear and tear, the O-ring can deform or become damaged to the point where it no longer seals effectively. The dealer sells the O-rings only as part of the complete hose assembly. This OE FIX engine coolant pipe O-ring kit is designed to reduce repair expense while matching the performance of the original part on specified vehicles. The O-ring helps to prevent coolant leaks and should be replaced periodically or if the connection is disturbed during service. This kit is made with quality materials and is engineered for reliable performance and durability.
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Product Features:
- Direct replacement – this OE FIX coolant pipe O-ring kit is designed to help restore proper cooling system function and prevent coolant leaks on specified vehicles
- Cost-conscious repair – replacing just the sealing components instead of the complete hose keeps properly-functioning parts in service
- Durable construction – designed and manufactured to strict specifications for reliable performance
- Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
Dorman – Coolant Tee and Radiator Hose O-Ring Kit (OE Fix) (Part No.926-168)
from
$30.99
When the seals fail between an upper coolant tee and radiator hose, there typically hasn’t been a fix besides buying a whole new coolant tee. This Dorman OE FIX kit offers a cost effective direct replacement of worn O-rings.
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Product Features:
- Cost-effective repair – this kit allows you to directly replace coolant tee and radiator hose O-rings
- Complete set – includes two large and one small O-ring
- Application specific – strictly designed for certain Ford F150 and Mustang model years
- Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
Carquest Premium – Radiator Cap (Part No.10268)
from
$14.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.
Product Features:
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Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Motorcraft – Radiator Cap (Part No.RS-527)
from
$12.29
Radiator Cap
Dorman – Help – Radiator Drain Cocks (Part No.61134)
from
$8.49
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.
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Product Features:
- Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
- Durable construction – this part is made of quality materials for a long service life
- Saves money – offers original equipment quality at a competitive price
- Quality assured – this petcock has undergone virtual testing to assure proper fit and function
Dorman – Help – Radiator Drain Cocks (Part No.61127)
from
$7.49
This radiator drain petcock is a direct replacement for the original equipment plug that may have deteriorated or corroded. Made of quality materials, this petcock is engineered to strict standards for durable use over time.
Product Features:
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Product Features:
- Direct replacement – this radiator drain petcock matches the fit and function of the original equipment part
- Durable construction – this part is made of quality materials for a long service life
- Saves money – offers original equipment quality at a competitive price
- Quality assured – this petcock has undergone virtual testing to assure proper fit and function
Carquest Premium – Standard Thermostat: 192 Degrees (Part No.14269)
from
$17.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Motorad UltraStats – Thermostat: 192 Degrees (Part No.5378-192)
from
$36.99
UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resitance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components.
Product Features:
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Product Features:
- Heavy gauge stainless steel components offer increased reliability and long-lasting durability
- Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
- Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
- AccuSpring Design for stable temperature control and increased cabin comfort
Carquest Premium – Engine Coolant Reservoir Cap (Part No.10262)
from
$22.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.
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Product Features:
- Maintains proper cooling system pressure
- Easy installation and removal
- 100% tested to ensure proper pressure and longevity
- Meets all OEM specifications
Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54208)
from
$16.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.
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Product Features:
- Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
- Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
- Seamless fit – reverse-engineered from the original equipment to fit perfectly
- Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
Motorcraft – Original Equipment (O.E.) Sender Assembly (Part No.DY-1194)
from
$51.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.
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Product Features:
- Motorcraft and Ford Parts are used throughout Ford vehicles in a variety of applications that help ensure the proper build quality, integrity and long-lasting performance of every Ford car or truck.
- Motorcraft and Ford Parts are manufactured from first-quality materials – chosen specifically for maximum performance and application suitability.
- As with all Motorcraft and Ford Parts, any innovations or improvements developed since the vehicle’s manufacture are included in these after market replacement parts, ensuring the most current technology and performance.
Factory Air – Engine Coolant Temperature Sensor (Part No.36447)
from
$27.49
High quality OE replacement part with all components needed to complete the job
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Product Features:
- Contains gaskets, O-rings, or seals to properly replace the product
- Brass construction for accurate temperature sensing
- Color coded for easy identification
- Zinc coated terminal to resist corrosion
Victor Reinz – Engine Water Pump Gasket (Part No.71-14046-00)
from
$3.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.
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Product Features:
- Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
Victor Reinz – Engine Water Pump Gasket (Part No.71-14236-00)
from
$19.49
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.
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Product Features:
- Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
Dorman – Clutch Fan Blade: Plastic, Cost Effective and Reliable (Part No.620-166)
from
$186.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
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Product Features:
- Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
- Quality construction – manufactured from premium materials for a long service life
- Excellent value – original equipment quality at a lower price
- Quality tested – has undergone testing to ensure proper fit and performance
Dorman – Clutch Fan Blade: Plastic, Cost Effective and Reliable (Part No.621-591)
from
$113.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.
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Product Features:
- Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
- Quality construction – manufactured from premium materials for a long service life
- Excellent value – original equipment quality at a lower price
- Quality tested – has undergone testing to ensure proper fit and performance
Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4189)
from
$138.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
Product Features:
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Product Features:
- 100% tested for reliable performance
- Durable housing features precisely machined mounting surface for proper sealing and fitment
- Equipped with weep chamber or similar feature to help prevent unnecessary replacement
- Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
- All gaskets or seals necessary for water pump are included
- This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
- This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
- This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T5094)
from
$164.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
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Product Features:
- Built to meet or exceed OE fit, form and function
- All components necessary for installation are supplied with pump
- 100% tested for reliable performance
- Follow all enclosed instructions to maximize pump life and validate warranty
Driveworks Water Pumps – Water Pump – Domestic Reman (Part No.58-554)
from
$108.99
100% leak testing And hub-pull testing ensures reliable performance. O.E.-supplied NEW unitized seals ensure long-lasting, trouble-free performance. Unlike other aftermarket manufacturers, CARDONE installs the proper O.E. specified bearing design to meet the specific radial And axial load requirements of each application. This ensures longer bearing life And reliable performance. Original casting specifications are strictly followed to ensure proper fit for easy installation And proper water flow for maximum cooling.
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Product Features:
- 100% leak testing and hub-pull testing ensures reliable performance.
- O.E.-supplied NEW unitized seals ensure long-lasting, trouble-free performance.
- The proper O.E. specified bearing design is installed to meet the specific radial and axial load requirements of each application. This ensures longer bearing life and reliable performance.
- Thermostat seal and mounting gasket are supplied for ease of installation (where applicable).
Carquest Premium – Engine Coolant Integrated Thermostat Housing (Part No.85691)
from
$45.49
High quality OE replacement part with all components needed to complete the job.
Product Features:
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Product Features:
- Meets and/or exceeds OEM standard
- Includes quality gasket or O-ring to ensure proper seal (where applicable)
- Includes quality gasket or O-ringá to ensure proper seal (where applicable)
- Coated with corrosion and rust inhibitor
- 100% leak tested
- All-in-one bolt on solution for a complete repair
- Includes quality thermostat
- Meets and/or exceeds OEM standard
- Includes quality gasket or O-ring to ensure proper seal (where applicable)
- Coated with corrosion and rust inhibitor
- 100% leak tested
- All-in-one bolt on solution for a complete repair
Dorman – Coolant Housing/Water Outlet: with Housing and Gasket, 90 Degree Neck Angle (Part No.902-1004)
from
$34.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
Product Features:
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Product Features:
- Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
- Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
- Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
- Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
Dorman – Coolant Housing/Water Outlet: with Housing (Part No.902-759)
from
$47.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.
Product Features:
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Product Features:
- Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
- Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
- Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
- Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
Popular 2021 Ford F-350 Super Duty Engine Cooling Parts Categories
Most Popular Radiator for 2021 Ford F-350 Super Duties
Enhance your 2021 Ford F-350 Super Duty with this popular Radiator we have in stock, for $583.99.
Carquest Premium – Radiator (Part No.4113716)
from
$583.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.
Product Features:
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Product Features:
- Thermal tested under real-life temperature simulations
- High tensile strength aluminum for maximum crimp strength
- Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
- Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Best-Selling 2021 Ford F-350 Super Duty Thermostat and Water Outlet Gasket
Upgrade your F-350 Super Duty with our best-selling Thermostat and Water Outlet Gasket with a 4.5 Starts rating across 110 reviews.
Felpro – Multi-Purpose O-Ring (Part No.35489)
from
$10.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.
Product Features:
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Product Features:
- Meets or exceeds all original equipment specifications
- Application specific design
- Manufactured for the sealing repair environment
- Validated for fit, form, and function
- Quality that you can trust
Top-Quality Water Pumps for 2021 Ford F-350 Super Duties
Choose a high-quality OEM or aftermarket Water Pump for Ford F-350 Super Duties and enjoy top-notch performance from $179.99.
Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T4221)
from
$179.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
Product Features:
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Product Features:
- 100% tested for reliable performance
- Durable housing features precisely machined mounting surface for proper sealing and fitment
- Equipped with weep chamber or similar feature to help prevent unnecessary replacement
- Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
- All gaskets or seals necessary for water pump are included
- This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
- This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
- This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T1305)
from
$231.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.
Product Features:
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Product Features:
- 100% tested for reliable performance
- Durable housing features precisely machined mounting surface for proper sealing and fitment
- Equipped with weep chamber or similar feature to help prevent unnecessary replacement
- Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
- All gaskets or seals necessary for water pump are included
- This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
- This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
- This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
Top Picks for 2021 Ford F-350 Super Duty Thermostats
Invest in one of our 9 durable Thermostats for your 2021 Ford, knowing you’re getting trusted brands and expert craftsmanship.
Carquest Premium – High Flow Thermostat: 170 Degrees (Part No.13967)
from
$14.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- Larger opening for increased coolant flow
- Increased strength and durability
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13778)
from
$15.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Motorad UltraStats – UltraStat Thermostat: 180 Degrees (Part No.5228-180JV)
from
$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.
Product Features:
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Product Features:
- Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
- Heavy gauge stainless steel components offer increased reliability and long-lasting durability
- Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
- AccuSpring Design for stable temperature control and increased cabin comfort
Carquest Premium – High Flow Thermostat: 180 Degrees (Part No.13968)
from
$12.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- Larger opening for increased coolant flow
- Increased strength and durability
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: 195 Degrees (Part No.14989)
from
$16.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Motorad UltraStats – UltraStat Thermostat: 195 Degrees (Part No.5228-195JV)
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$18.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.
Product Features:
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Product Features:
- Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
- Heavy gauge stainless steel components offer increased reliability and long-lasting durability
- Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
- AccuSpring Design for stable temperature control and increased cabin comfort
Carquest Premium – Standard Thermostat: With Seal, 194, 201 Degrees (Part No.49240)
from
$59.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: With Seal, 160 Degrees, 170 Degrees (Part No.717-160)
from
$84.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Carquest Premium – Standard Thermostat: With Seal, 192 Degrees (Part No.1121-192)
from
$62.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Our Thermostat and Water Outlet Assemblies for 2021 Ford F-350 Super Duties
Make a smart move for your 2021 Ford F-350 Super Duty with our Thermostat and Water Outlet Assembly for $2,150.99.
Motorad – Thermostat Housing Assembly – 194 & 201 Degrees (Part No.TA1061)
from
$2150.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.
Product Features:
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Product Features:
- High grade stainless steel and copper construction
- Meets or exceeds OEM standards
- Consistent and precise response to cooling system needs
- Original equipment design for worry-free direct fit replacement
- 100% tested and calibrated
Top-Rated Engine Cooling Part Brands For Your 2021 Ford F-350 Super Duty
When it comes to finding the perfect Engine Cooling Part for your 2021 Ford F-350 Super Duty, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 7 trusted brands. We carry the most popular Engine Cooling Part brands including FELPRO, Carquest Premium, and Dorman, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $7.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2021 Ford F-350 Super Duty, providing peace of mind with parts that meet or exceed OEM standards.
Popular FELPRO 2021 Ford F-350 Super Duty Engine Cooling Parts
If you’re looking for a top-quality Engine Cooling Part for your 2021 Ford F-350 Super Duty, Advance Auto Parts has exactly what you need with our selection of FELPRO Engine Cooling Parts. We have 2 FELPRO Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $7.99 and an average cost of $9.49, you’ll find the perfect Engine Cooling Part for your needs and budget. FELPRO Engine Cooling Parts for the 2021 Ford F-350 Super Duty come highly rated, with over 121 customer reviews and an impressive average rating of 4.6 stars. Choosing a FELPRO Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Top-Quality Carquest Premium 2021 Ford F-350 Super Duty Engine Cooling Parts
For those in search of a high-quality Engine Cooling Part for their 2021 Ford F-350 Super Duty, Advance Auto Parts offers a great selection of Carquest Premium Engine Cooling Parts. With 3 Carquest Premium Engine Cooling Parts in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Engine Cooling Parts start at just $12.99, with an average price of $14.66, giving you a range of options to suit your budget. Backed by over 34 customer ratings and an average rating of 4.4 stars, Carquest Premium Engine Cooling Parts provide both reliability and excellent performance. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.
from
$15.99
(16)
Standard Thermostat: 180 Degrees
“Car did not run hot, but lower radiator hose started leaking and was too hot to touch. Replaced and lower radiator hose temp was much cooler. Car runs”
FAQs for 2021 Ford F-350 Super Duty Engine Cooling Parts
What are the best-selling Engine Cooling Parts for 2021 Ford F-350 Super Duties?
Out of 27 Engine Cooling Parts that fit 2021 Ford F-350 Super Duties, the following parts are the top sellers:
- High Flow Thermostat: 170 Degrees (5653495) – $14.99
- UltraStat Thermostat: 195 Degrees (11920679) – $18.99
- Standard Thermostat: 180 Degrees (15480095) – $15.99
What’s the price range for 2021 Ford F-350 Super Duty Engine Cooling Parts?
The prices of Engine Cooling Parts for the 2021 Ford F-350 Super Duty range from $2.99 up to $2,150.99 for the most premium parts.
What is the average price of an Engine Cooling Part for a 2021 Ford F-350 Super Duty?
The average price for Engine Cooling Parts for the 2021 Ford F-350 Super Duty is $125.51. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.
Does Advance Auto Parts sell Engine Cooling Parts for other Ford F-350 Super Duty model years?
What are the cheapest Engine Cooling Parts for my 2021 Ford F-350 Super Duty?
The cheapest 2021 Ford F-350 Super Duty Engine Cooling Parts we carry are:
- THERMOSTAT O-RING (50213631) – $2.99
- Engine Water Pump Gasket (19780363) – $7.99
- Radiator Drain Cocks (89015360) – $8.49
- Coolant Temperature Sensor 1TS1488 (50215081) – $8.99
- Multi-Purpose O-Ring (5180902) – $10.99
Does Advance Auto Parts sell Engine Cooling Parts for any other 2021 Ford models?
Yes. We stock Engine Cooling Parts for 23 other popular 2021 Ford models. Some of the most popular are 2021 F-150 Engine Cooling Parts, 2021 Mustang Engine Cooling Parts, 2021 Explorer Engine Cooling Parts, 2021 Bronco Engine Cooling Parts, and 2021 F-250 Super Duty Engine Cooling Parts.
What are the top-rated Engine Cooling Parts that fit the 2021 Ford F-350 Super Duty?
The one 2021 Ford F-350 Super Duty Engine Cooling Part we have in stock is the THERMOSTAT O-RING. It costs $2.99.
What types of Engine Cooling Parts do you sell for my 2021 Ford F-350 Super Duty?
As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2021 Ford F-350 Super Duty:
Can I get help with 2021 Ford F-350 Super Duty Engine Cooling Part orders?
Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Engine Cooling Parts and more.
What is your return policy for Ford F-350 Super Duty Engine Cooling Parts?
Advance Auto Parts keeps returns simple. For new Ford F-350 Super Duty Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.