2006 GMC Sierra 2500 HD Cooling and Climate Controls

Essential 2006 GMC Sierra 2500 HD Cooling and Climate Controls

FAE – Engine Coolant Temperature Sensor (Part No.C6020175714FAE)

Engine Coolant Temperature Sensor

from

$23.58
The FAE Engine Coolant Temperature Sensor is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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Carquest Premium – 4 Pole Radiator Fan Motor (Part No.75768)

4 Pole Radiator Fan Motor

from

$126.99
Motor RPM equivalent to or exceeds OEM motor

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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Dorman – Engine Heater Hose Assembly (Part No.626-591)

Engine Heater Hose Assembly

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$89.99
This replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models
  • Restores functionality – reliable replacement for an original part that is leaking, cracked or failed from corrosion and heat
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Motorad – Standard Thermostat: With Seals, 180, 185 Degrees (Part No.447448)

Standard Thermostat: With Seals, 180, 185 Degrees

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$40.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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GM Genuine Parts – Multi-Purpose Relay (Part No.15016745)

Multi-Purpose Relay

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$49.49
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps connect or disconnect power to vehicle accessories
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Factory Air – Coolant Temp Sensor Switch (Part No.36403)

Coolant Temp Sensor Switch

from

$24.05
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Brass construction for accurate temperature sensing
  • Color coded for easy identification
  • Zinc coated terminal to resist corrosion
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.45813)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

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$1.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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ACDelco – Ambient Temp Sensor (Part No.P4025600368ACD)

Ambient Temp Sensor

from

$12.37
Ambient Temp Sensor

ACDelco – A/C Manifold Hose As (Part No.R1020439171ACD)

A/C Manifold Hose As

from

$417.35
A/C Manifold Hose As

Felpro – Engine Water Pump Installation Kit (Part No.ES 71347)

Engine Water Pump Installation Kit

from

$31.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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ACDelco – 12587397 GM Original Equipment Engine Coolant Water Inlet Seal (Part No.G4030310258ACD)

12587397 GM Original Equipment Engine Coolant Water Inlet Seal

from

$8.72
An ACDelco GM Original Equipment Engine Coolant Water Inlet Seal is a GM-recommended replacement for your vehicle’s original component. It seals and helps prevent coolant from leaking out of cooling system components. This original equipment engine coolant water inlet seal has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Seals and helps prevent coolant from leaking out of cooling system components to maintain the proper engine temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Dorman – Water Pump Outlet Pipe (Part No.626-661)

Water Pump Outlet Pipe

from

$82.99
This engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles. It is engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion..

Product Features:
  • Direct replacement – this engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles.
  • Ideal solution – engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
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Carquest Premium – A/C New; w/ Clutch; w/ 7SAS17F Compressor (Part No.T168305)

A/C New; w/ Clutch; w/ 7SAS17F Compressor

from

$576.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.

Product Features:
  • Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
  • New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
  • The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
  • All new compressors must pass a helium leak test and pump up function test prior to packaging.
  • O-Rings and gaskets necessary for installation are included.
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GM Genuine Parts – Multi-Purpose Relay (Part No.15-81106)

Multi-Purpose Relay

from

$32.99
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps connect or disconnect power to vehicle accessories
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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ACDelco – Gray Multi-Purpose Pigtail (Part No.PT2655)

Gray Multi-Purpose Pigtail

from

$72.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-514)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

from

$92.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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KAI – Radiator Support (Part No.GM1225265)

Radiator Support

from

$59.99
New Standard Replacement Radiator Support Center

Product Features:
  • Made Of Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

from

$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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GM Genuine Parts – Heating and Air Conditioning Blower Control Module (Part No.15-81773)

Heating and Air Conditioning Blower Control Module

from

$72.99
GM Genuine Parts HVAC Blower Motor Control Modules are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These modules are microprocessor computers that modulate HVAC blower motor speed. The blower motor control module receives input from the HVAC control module. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Designed and tested to help ensure quality and durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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ACDelco – Heating and Air Conditioning Panel Mode Door Actuator (Part No.15-73620)

Heating and Air Conditioning Panel Mode Door Actuator

from

$71.99
ACDelco GM Original Equipment HVAC Mode Door Actuators are electric motors attached to the HVAC housing that move or actuate the mode doors or flaps, directing the airflow to the desired outlet vents. These original equipment HVAC mode door actuators are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Corrects mode door malfunction caused by a failed actuator
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Santech – A/C Service Valve Fi (Part No.R11491515863SII)

A/C Service Valve Fi

from

$3.77
A/C Service Valve Fi

Permatex – Ultra Grey RTV Silicone Gasket Maker, 13 OZ (Part No.82195)

Ultra Grey RTV Silicone Gasket Maker, 13 OZ

from

$26.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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Carquest Premium – A/C Compressor and Component Kit (Part No.4108K)

A/C Compressor and Component Kit

from

$293.99
Save time on installation with everything you need in one box for an air conditioning replacement. The Carquest Premium A/C Compressor and Component Kit includes the necessary compressor, accumulator/receiver drier, and orifice tube/expansion valve, along with the necessary O-rings, gaskets, and oil. The parts are manufactured with strict quality standards from Gilmore, a climate control partner to Advance Auto Parts for over 25 years.

Product Features:
  • Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
  • New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
  • The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
  • All new compressors must pass a helium leak test and pump up function test prior to packaging.
  • Accumulators and receiver driers meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
  • Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
  • All accumulators are helium leak tested prior to packaging.
  • Each orifice tube and expansion valve is tested for function and leakage according to OEM specifications to ensure optimal performance of the air conditioning system.
  • The specific PAG oil required by your vehicle application is included.
  • O-rings and gaskets for all parts are application specific and packaged with the correct part to save time and eliminate the possibility of a leak from using the wrong O-ring or gasket.
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Carquest Premium – Radiator: With Engine And Transmission Oil Coolers (Part No.438060)

Radiator: With Engine And Transmission Oil Coolers

from

$499.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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Imperial – Thermostatic Fan Control – Adjustable (Part No.226208)

Thermostatic Fan Control - Adjustable

from

$62.99
Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160°F – 210°F thread-in probe
  • For use with Imperial electric fans
  • Thread-in probe for installation in water jacket or radiator
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Factory Air – New Nippondenso 10S17F Clutch Assembly w/ Coil (Part No.47362)

New Nippondenso 10S17F Clutch Assembly w/ Coil

from

$181.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • All mounting hardware included
  • Every coil tested for proper ohms
  • Vehicle specific applications
  • Coated to prevent corrosion
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Carquest Premium – A/C Compressor Switch Connector (Part No.PTA1328)

A/C Compressor Switch Connector

from

$15.79
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Carquest Premium – Brake Pressure Modulator Sensor Connector (Part No.PTA1017)

Brake Pressure Modulator Sensor Connector

from

$28.49
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Popular 2006 GMC Sierra 2500 HD Cooling and Climate Controls Categories

2006 GMC Sierra 2500 HD Cooling and Climate Controls

You count on your 2006 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 302 Cooling and Climate Controls ranging in price from $1.29 to $551.99, you’re sure to find everything you need for your 2006 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 26 different brands like Carquest Premium, Permatex, and DriveWorks. 2006 GMC Sierra 2500 HD Cooling and Climate Controls start as low as $1.29!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 24,900 extensive product reviews on 2006 GMC Sierra 2500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Engine Water Pump Gasket with 4.7 stars and A/C Dark Grey Porous Orifice Tube with 4.7 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2006 GMC Sierra 2500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2006 GMC Sierra 2500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2006 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Permatex, DriveWorks, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Engine Cooling Parts and Blower Motor and Related Products. All are waiting to get your 2006 GMC Sierra 2500 HD back on the road. Some of the top-rated ACDelco products in these categories are:
Engine Coolant Temperature Sensor
from $34.99
(1)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors
Multi-Purpose Relay
from $29.99
(1)
Multi-Purpose Relay
Blower Relays
Heating and Air Conditioning Panel Mode Door Actuator
from $77.99
(1)
Heating and Air Conditioning Panel Mode Door Actuator
Heater Blend Doors

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2006 GMC Sierra 2500 HD, and some of our most reviewed Carquest Premium parts include:
Engine Water Pump: New, Gasket/Seals Included
from $153.99
(371)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps
Standard Thermostat: With Seal, 187 Degrees
from $18.79
(189)
Standard Thermostat: With Seal, 187 Degrees
Thermostats

FAQs for 2006 GMC Sierra 2500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2006 GMC Sierra 2500 HD?

Out of 302 Cooling and Climate Controls for the 2006 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Water Pump Gaskets
Engine Water Pump
from $101.99
(345)
Engine Water Pump
Water Pumps
Standard Thermostat: With Seal, 195 Degrees
from $7.29
(105)
Standard Thermostat: With Seal, 195 Degrees
Thermostats

What are the top-rated 2006 GMC Sierra 2500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2006 GMC Sierra 2500 HD based on customer reviews/ratings are:
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
“Great product …easy to use”
A/C Dark Grey Porous Orifice Tube
from $15.99
(97)
A/C Dark Grey Porous Orifice Tube
“Picture says it all – the 12-yr old tube was pretty filthy and not reusable. If you’re working on your A/C, this is a good item to replace while you'”
Blower Motor: With Wheel
from $118.99
(78)
Blower Motor: With Wheel
“Thank you”