Lexus RX350 Transmission Fluids

Your One-Stop Shop For Trusted Lexus RX350 Transmission Fluids

If you’re in search of Lexus RX350 Transmission Fluids aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 13 Transmission Fluids from top brands with prices ranging from $9.99 to $85.99.

Beyond great prices, we stock trusted brands manufacturing all types of Transmission Fluids for your Lexus RX350. Of the 6 OEM and aftermarket parts brands we carry, some of the most popular are Valvoline, Fram, and Royal Purple.

And don’t forget to read customer reviews across all Transmission Fluids categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Transmission Fluids have to cost top dollar, and we prove it. Browse our top Lexus RX350 Transmission Fluids below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Lexus RX350 Transmission Fluids

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Gallon

from

$36.49
Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid (ATF) is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
  • Long life friction modifiers help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
  • Suitable for 95% of traditional ATFs including Dex/Merc, Mercon LV & Mercon V
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FRAM – Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon (Part No.F426-1G)

Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon

from

$33.99
FRAM DEXRON®-VI FULL SYNTHETIC ATF represents the latest technology in full  synthetic automatic transmission fluids. This product is designed for the newest  generation of highly efficient transmissions now being installed in most vehicles, and is  DEXRON®-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel  efficient choice for older models as well, such as those currently using DEXRON®-III. FRAM DEXRON®-VI FULL SYNTHETIC ATF is recommended for use in all GM  DEXRON® applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations.

Product Features:
  • Outstanding resistance to oxidative and thermal breakdown.
  • Exceptional low temperature fluidity.
  • Excellent anti-wear properties.
  • Excellent gear shift quality throughout service life.
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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ATP – Auto Trans Fluid (Part No.AT-216)

Auto Trans Fluid

from

$22.99
Product Features:
  • Fully Synthetic
  • Advance transmission protection from standard to sever duty
  • Resist thermal breakdown, oxidation, varnish and sludge
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FRAM – Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart (Part No.F426)

Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart

from

$11.79
FRAM DEXRON®-VI FULL SYNTHETIC ATF represents the latest technology in full  synthetic automatic transmission fluids. This product is designed for the newest  generation of highly efficient transmissions now being installed in most vehicles, and is  DEXRON®-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel  efficient choice for older models as well, such as those currently using DEXRON®-III. FRAM DEXRON®-VI FULL SYNTHETIC ATF is recommended for use in all GM  DEXRON® applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations.

Product Features:
  • Outstanding resistance to oxidative and thermal breakdown.
  • Exceptional low temperature fluidity.
  • Excellent anti-wear properties.
  • Excellent gear shift quality throughout service life.
  • ALWAYS REFER TO YOUR VEHICLES OPERATING MANUAL TO SELECT THE CORRECT GRADE FLUID FOR YOUR TRANSMISSION
  • TRANSMISSION FLUIDS ALSO APPLICABLE IN POWER STEERING UNITS; CHECK OWNERS’ MANUAL
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Castrol – Transmax ATF Full Synthetic Multi-Vehicle Automatic Transmission Fluid (1 Quart) (Part No.152A76)

Transmax ATF Full Synthetic Multi-Vehicle Automatic Transmission Fluid (1 Quart)

from

$12.29
Automatic transmission fluid is a technologically advanced, low viscosity formulation specially designed to deliver performance and maximum fuel efficiency for modern automatic transmissions.

Product Features:
  • Full Synthetic, low viscosity formulation
  • OEM approved and licensed by Ford (MERCON® LV) and GM (DEXRON® -VI)
  • Low viscosity formula for maximum fuel efficiency in modern automatic transmissions
  • Enhanced friction durability for smooth transmission performance
  • Superior high temperature protection to effectively resist oxidation
  • Unsurpassed protection against copper corrosion
  • Industry Specifications and OEM Approvals: JASO-1A
  • Licensed and approved for use in: All GM vehicles (DEXRON®-VI, All previous DEXRON®); All Ford vehicles which specify Mercon® LV
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Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 1 Quart (Part No.VV1556/VV155)

High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 1 Quart

from

$9.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
  • MaxLife Technology: Valvoline High Mileage with MaxLife Technology is specially formulated to maximize engine life in vehicles with over 75,000 miles, providing superior protection against wear, friction, heat, and deposits.
  • Synthetic Blend Composition: This motor oil features a unique combination of synthetic and premium conventional oils, ensuring optimal performance and protection for high-mileage engines.
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Royal Purple – HMX 5W-20 High Mileage Synthetic Motor Oil, 1 Quart (Part No.17511)

HMX 5W-20 High Mileage Synthetic Motor Oil, 1 Quart

from

$13.49
Royal Purple HMX SAE 5W-20 High-Mileage Synthetic Motor Oil, 1 quart is specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles. Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology Synerlec, HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines. In addition, HMX is fortified with stout detergents to remove engine build-up and deposits, maintain cleanliness and promote engine longevity.

Product Features:
  • Specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles
  • Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology
  • HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines
  • Reduces friction and metal-to-metal contact for peak engine performance
  • Also provides outstanding oxidation resistance to safely extend oil drain intervals, and an ionic attraction to metal surfaces, providing protection and minimizing wear at start-up
  • Superior Engine Cleanliness: Fortified with stout detergents, this oil effectively removes engine build-up and deposits, maintaining cleanliness and promoting engine longevity.
  • High-Mileage Protection: Classified as high mileage and composed of synthetic oil, it provides superior protection and performance for older engines.
  • Optimal Viscosity: With an SAE oil weight of 5W-20, it ensures optimal viscosity for high-mileage engines, enhancing overall engine efficiency and longevity.
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Royal Purple – HMX SAE 5W-30 High-Mileage Synthetic Engine Oil (1 Quart) (Part No.11744)

HMX SAE 5W-30 High-Mileage Synthetic Engine Oil (1 Quart)

from

$12.99
Royal Purple HMX SAE 5W-30 High-Mileage Synthetic Motor Oil, 1 quart is specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles. Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology Synerlec, HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines. In addition, HMX is fortified with stout detergents to remove engine build-up and deposits, maintain cleanliness and promote engine longevity.

Product Features:
  • Specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles
  • Formulated with robust zinc/phosphorus anti-wear compounds combined with royal purple’s proprietary additive technology
  • Hmx is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines
  • Reduces friction and metal-to-metal contact for peak engine performance
  • Also provides outstanding oxidation resistance to safely extend oil drain intervals, and an ionic attraction to metal surfaces, providing protection and minimizing wear at start-up
  • High-Mileage Formula: Specifically designed for engines with more than 75,000 miles, this full synthetic engine oil helps minimize wear and restore lost performance.
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Valvoline – Extended Protection Automatic Transmission Fluid – 6 Quarts (Part No.899179)

Extended Protection Automatic Transmission Fluid - 6 Quarts

from

$14.99
Extended Protection Automatic Transmission Fluid – 6 Quarts

Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart (Part No.881163)

High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart

from

$29.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
  • MaxLife Technology: Valvoline High Mileage with MaxLife Technology is specially formulated to maximize engine life in vehicles with over 75,000 miles, providing superior protection against wear, friction, heat, and deposits.
  • Synthetic Blend Composition: This motor oil features a unique combination of synthetic and premium conventional oils, ensuring optimal performance and protection for high-mileage engines.
See More

Pentosin – PENTOSIN ATF 44 5L (Part No.1058212)

PENTOSIN ATF 44 5L

from

$85.99
PENTOSIN ATF 44 5L

Royal Purple – High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT (Part No.01530)

High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT

from

$12.99
High Performance Motor Oil API LICENSED MOTOR OIL Royal Purple High Performance Motor Oil combines premium base oils with proprietary additive technologies to create a high performance synthetic engine oil that optimizes performance and protection. Royal Purple High Performance Motor Oils carry the current API and ILSAC engine oil licenses, as well as the GM dexos1 gasoline engine oil approval. ILSAC GF-6 AND GM DEXOS1 Modern gasoline direct injection (GDI) engines have achieved levels of power and fuel economy never before possible in passenger car engines. As a result, smaller engines operate at much higher loads across all engine speeds. This has caused increased wear in critical areas of the engine, and created a destructive phenomenon called low-speed pre-ignition (LSPI). The unique, state-of-the-art additive technology in Royal Purple High Performance engine oils is designed specifically to address these issues, and help engines maintain performance and reliability.

Product Features:
  • Better Wear Protection
  • Increased Protection against Low Speed Pre-Ignition
  • Increased Fuel Efficiency
  • Better Protection for Vehicle Exhaust Emissions Equipment
  • Improved Compatibility with Fuels Containing Ethanol
  • Superior Corrosion Protection
  • Made in USA
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Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart (Part No.782256)

High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart

from

$31.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
See More

Transmission Fluids Brands You Can Trust For Your Lexus RX350

6 trusted brands of Transmission Fluids line our shelves, ready to help keep your Lexus RX350 running smooth. Below are some of the most popular brands and their top Transmission Fluids offerings:

Top Lexus RX350 Transmission Fluids from Valvoline

Your Lexus RX350 will be purring again thanks to Valvoline brand Transmission Fluids available for online order or in-store pick up. Popular Valvoline parts include:

Most Purchased Lexus RX350 Transmission Fluids from Valvoline

When you buy the most frequently purchased Valvoline brand Transmission Fluids, you can be confident it will be the right part for your Lexus RX350. Here are the Valvoline Transmission Fluids Advanced Auto customers buy the most:
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
from $33.99
This product is not rated
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
Automatic Transmission Fluids

FAQs for Lexus RX350 Transmission Fluids

What are the most purchased Transmission Fluids for the Lexus RX350?

Out of 13 Transmission Fluids for the Lexus RX350, the most popular in our inventory are:
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
from $33.99
This product is not rated
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon
Automatic Transmission Fluids
High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT
from $12.99
(82)
High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT
Manual Transmission Fluids
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart
from $11.79
This product is not rated
Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart
Automatic Transmission Fluids

What are the top-rated Lexus RX350 Transmission Fluids?

Top-rated Transmission Fluids for your Lexus RX350 based on customer reviews/ratings are: