Ford F-350 Pickup Axle Shaft Seals

Your Ford F-350 Pickup will be happy to know that the search for the right Axle Shaft Seals you’ve been looking for is over! Advance Auto Parts has 14 different Axle Shaft Seals for your vehicle, ready for shipping or in-store pick up. The best part is, our Ford F-350 Pickup Axle Shaft Seals start from as little as $4.29.

When it comes to your Ford F-350 Pickup, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Axle Shaft Seals brands so you can shop with complete confidence. Some of our top Axle Shaft Seals brands are National and Dorman. We’re sure you will get the right product to keep that F-350 Pickup running for a long time.

We even have reviews of our OEM and aftermarket Axle Shaft Seals products to help you buy with confidence. Hear from other customers via the 1,244 reviews on parts for your Ford F-350 Pickup.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Axle Shaft Seals for your F-350 Pickup, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 25 Ford Axle Shaft Seals

Driveworks – Oil Seal (Part No.S-8660S)

Oil Seal

from

$5.49
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
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National – Multi Purpose Seal (Part No.710685)

Multi Purpose Seal

from

$64.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Oil Seal (Part No.S-100357)

Oil Seal

from

$9.49
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710493)

Multi Purpose Seal

from

$66.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.2146)

Multi Purpose Seal

from

$18.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Axle Shaft Seal (Part No.710950)

Axle Shaft Seal

from

$25.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – Multi Purpose Seal (Part No.710492)

Multi Purpose Seal

from

$49.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.100537)

Multi Purpose Seal

from

$15.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: springless; single-lip
  • Temperature range: -100°F to 450°F; -73°C to 232°C
  • Resistant to hydrocarbon/oxygenate blends and provides superior performance
  • Provides excellent dry running capabilities, low coefficient of friction and excellent resistance to chemicals
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710494)

Multi Purpose Seal

from

$91.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Oil Seal (Part No.S-2146)

Oil Seal

from

$4.29
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710065)

Multi Purpose Seal

from

$21.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.714569)

Multi Purpose Seal

from

$15.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.8835S)

Multi Purpose Seal

from

$10.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.5131)

Multi Purpose Seal

from

$14.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710428)

Multi Purpose Seal

from

$30.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710429)

Multi Purpose Seal

from

$19.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Dorman – Rear Axle O-Ring Kit (Part No.926-129)

Rear Axle O-Ring Kit

from

$10.99
The axle shaft o-ring seals the rear axle to the wheel hub. The symptom of a failed axle shaft o-ring is an axle fluid leak around wheel hub. This is an ideal repair solution to prevent axle fluid leaks from forming around the wheel hub.

Product Features:
  • Aftermarket exclusive replacement part
  • Recommended for replacement when servicing vehicle brakes
  • Direct replacement for original equipment
  • This part has undergone extensive vehicle try-on and durability testing to ensure strength, fitment and longevity
See More

National – Multi Purpose Seal (Part No.710396)

Multi Purpose Seal

from

$13.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Wheel Seal (Part No.S-710429)

Wheel Seal

from

$11.99
Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710825)

Multi Purpose Seal

from

$91.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Dorman – Rear Axle O-Ring Kit (Part No.926-163)

Rear Axle O-Ring Kit

from

$16.29
The axle shaft o-ring seals the rear axle to the wheel hub. The symptom of a failed axle shaft o-ring is an axle fluid leak around wheel hub. This is an ideal repair solution to prevent axle fluid leaks from forming around the wheel hub.

Product Features:
  • Aftermarket exclusive replacement part
  • Recommended for replacement when servicing vehicle brakes
  • Direct replacement for original equipment
  • This part has undergone extensive vehicle try-on and durability testing to ensure strength, fitment and longevity
See More

SKF – Axle Seal (Part No.K4021285300SKF)

Axle Seal

from

$7.11
SKF’s advanced PTFE oil seal offers optimum performance in extreme temperature and fluid environments. Other benefits of this seal include; reduced friction, longer service life, easier assembly, reduced weight and compact design.

Product Features:
  • Machined rubber sealing edge provides greater accuracy and consistency, as well as a better sealing surface.
  • The flanged design allows for easier and proper installation and helps avoid cocking.
  • The latex bore coat seals the outer diameter leak path and helps compensate for minor bore imperfections.
  • Extra dust lip helps keep harmful contaminants, such as dirt, out of the bearing and protects against rust and corrosion.
See More

National – Multi Purpose Seal (Part No.710043)

Multi Purpose Seal

from

$17.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Yukon Gear – Dana 44 / 60 And GM 8.5" Inner Front Disconnect Seal Replacement (Part No.30122)

Dana 44 / 60 And GM 8.5" Inner Front Disconnect Seal Replacement

from

$13.99
Inner front disco replacement seal for 4WD Dana 44, Dana 60, and 8.5″ straight axle.Yukon Mighty seal.

Product Features:
  • Inner front axle seal
  • Fits Dodge disconnect front with Dana Spicer 44 or 60, reverse rotation Dana Spicer 44 and GM 8.5″
See More

Dorman – Rear Axle O-Ring Kit (Part No.926-164)

Rear Axle O-Ring Kit

from

$18.99
The axle shaft o-ring seals the rear axle to the wheel hub. The symptom of a failed axle shaft o-ring is an axle fluid leak around wheel hub. This is an ideal repair solution to prevent axle fluid leaks from forming around the wheel hub.

Product Features:
  • Aftermarket exclusive replacement part
  • Recommended for replacement when servicing vehicle brakes
  • Direct replacement for original equipment
  • This part has undergone extensive vehicle try-on and durability testing to ensure strength, fitment and longevity
See More

FAQs for Ford F-350 Pickup Axle Shaft Seals

What are the most popular Axle Shaft Seals for the Ford F-350 Pickup?

With 6 brands you can trust, our most popular Axle Shaft Seals for the Ford F-350 Pickup are:
Multi Purpose Seal
from $18.99
(14)
Multi Purpose Seal
Axle Shaft Seals
Multi Purpose Seal
from $14.99
(20)
Multi Purpose Seal
Axle Shaft Seals
Multi Purpose Seal
from $49.99
(5)
Multi Purpose Seal
Axle Shaft Seals