Ford F-250 Pickup Drive Shafts and Axles

Your One-Stop Shop For Trusted Ford F-250 Pickup Drive Shafts and Axles

If you’re in search of Ford F-250 Pickup Drive Shafts and Axles aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 115 Drive Shafts and Axles from top brands with prices ranging from $4.29 to $1,237.99.

Beyond great prices, we stock trusted brands manufacturing all types of Drive Shafts and Axles for your Ford F-250 Pickup. Of the 16 OEM and aftermarket parts brands we carry, some of the most popular are National, Spicer, and Dorman.

And don’t forget to read customer reviews across all Drive Shafts and Axles categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Drive Shafts and Axles have to cost top dollar, and we prove it. Browse our top Ford F-250 Pickup Drive Shafts and Axles below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Ford F-250 Pickup Drive Shafts and Axles

Driveworks – Axle Shaft Bearing (Part No.S-HK-4012)

Axle Shaft Bearing

from

$10.79
Product Features:
  • Brand may vary by location
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Yukon Gear – Dana 60/70 Rear Axle Bearing And Seal Kit Replacement (Part No.10055)

Dana 60/70 Rear Axle Bearing And Seal Kit Replacement

from

$136.99
Yukon axle bearing & seal kits are specially designed for each application & use all high quality bearings & seals. Ford E350/F350 F/F Dana 60 & Dana 70 rear replacement axle bearing kit, 67-97. This axle bearing & seal kit services one side only.

Product Features:
  • Fits 1967-1997 Ford F350 and E350 rear with Dana Spicer 60 or 70
  • Includes inner and outer bearings and races and axle seal
  • Services one side
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Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$20.29
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6038)

Center Support Bearing Motor Mount: Center, 1 Piece

from

$34.49
Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to AUTOCAR 84-88; CHEV 60-02; DODGE 57-02; FORD 55-07; GMC 63-02; INTL 57-02; KW 81-18; MACK 80-83; PTRB 65-83; WHGM 88-95; WHIT 81-88;. Please verify your application.

Product Features:
  • MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
  • HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
  • READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
  • For Years: 1955-2018
  • Weight approx: 4 Lbs
  • BEARING ID / BORE: 1.5750 INCH / 40 MM
  • CENTERLINE: 2.48 INCH / 63 MM
  • MOUNT WIDTH: 6.62 INCH / 168 MM
  • STYLE: ROUND FRAME
  • NOT PICTURED: TWO DUST SHIELDS
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Yukon Gear – Replacement Redi-Sleeve Yoke Saver For Dana 25, Dana 27, Dana 30, Dana 44, Dana 50 (Part No.30222)

Replacement Redi-Sleeve Yoke Saver For Dana 25, Dana 27, Dana 30, Dana 44, Dana 50

from

$182.99
Replacement redi-sleeve yoke saver for Dana 25, Dana 27, Dana 30, Dana 44, Dana 50 .Yukon Mighty seal.

Product Features:
  • Pinion Redi-sleeve
  • Fits Dana Spicer 25, 27, 30, 4 and 50
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National – Bearings (Part No.M802011)

Bearings

from

$14.79
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
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NTN – Axle Shaft Bearing (Part No.K4010212752NTN)

Axle Shaft Bearing

from

$42.90
Axle Shaft Bearing

Yukon Gear – Replacement Axle Inner Axle Seal For Straight Axle Dana 50 & Dana 60 (Part No.30320)

Replacement Axle Inner Axle Seal For Straight Axle Dana 50 & Dana 60

from

$54.99
Replacement axle inner axle seal for straight axle Dana 50 & Dana 60 .Yukon Mighty seal.

Product Features:
  • Front inner axle seal
  • Fits Dana Spicer 50
  • Straight axle only
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Yukon Gear – 9.75" Ford C-Clip (Part No.33248)

9.75" Ford C-Clip

from

$16.99
9.75″ Ford C-Clip.

Product Features:
  • C-clip
  • Fits Ford 9.75″
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Timken – Driveshaft Support with Bearing (Part No.K1030195244TIM)

Driveshaft Support with Bearing

from

$57.17
The Timken Driveshaft Support is an ideal high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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Yukon Gear – Plug Adapter For Extra-Large Clamshell (Part No.56070)

Plug Adapter For Extra-Large Clamshell

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$47.99
Plug adapter for extra-large clamshell. No Return.

Product Features:
  • Plug adapter for Extra Large clamshell
  • Fits carrier bearing puller
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Yukon Gear – Axle Stud , 58Mm X M14-2.0 (Part No.33557)

Axle Stud , 58Mm X M14-2.0

from

$5.99
AXLE STUD , 58MM X M14-2.0 .
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Yukon Gear – Axle O-Ring For Ford 10.25" & 10.5" (Part No.33465)

Axle O-Ring For Ford 10.25" & 10.5"

from

$8.99
Product Features:
  • Axle o-ring
  • Fits Ford 10.25″ and 10.5″
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Spicer – Axle Shft Univ Joint (Part No.5-3226X)

Axle Shft Univ Joint

from

$47.99
Axle Shft Univ Joint

Yukon Gear – Drive Flange Cap For Dana 60 (Part No.32132)

Drive Flange Cap For Dana 60

from

$129.99
Product Features:
  • Drive flange cap
  • Fits Dana 60
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Dorman – Rear Axle Differential Vent (Part No.924-263)

Rear Axle Differential Vent

from

$9.49
This axle vent is designed to match the fit and function of the original vent on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this axle vent is designed to match the fit and function of the original vent on specified vehicles
  • Restores functionality – reliable replacement for an original vent that has failed due to blockage or fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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National – Shaft Repair Sleeve (Part No.99125)

Shaft Repair Sleeve

from

$27.49
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
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Yukon Gear – 4340 Chrome-Moly Outer Stub For Ford F250 With A Length Of 10.66", Uses 5-760X U/Joint (Part No.21357)

4340 Chrome-Moly Outer Stub For Ford F250 With A Length Of 10.66", Uses 5-760X U/Joint

from

$215.99
Yukon 4340 Chrome-Moly outer stub for Ford F250 with a length of 10.66″ and 19 splines. Yukon 4340 Chrome-Moly axles provide up to 50% increased strength over stock axles for use in extreme performance applications with large tires and high horsepower. Yukon’s 4340 axles are manufactured using the latest technologies and the highest quality materials to ensure high strength and long life. Limited Lifetime warranty covers manufacturing defects and axle breakage for as long as you own the vehicle. This warranty is not transferable to another party. “No Questions Asked” replacement for first warranty return, however Yukon reserves the right to either replace axle or refund original purchase price after the first warranty claim. Yukon (through Randy’s ring & pinion) makes final determination on warranty considerations.

Product Features:
  • Fits 1976-1977 Ford F250
  • 4340 Chromoly
  • Outer stub
  • 19 spline
  • 10.66″ from end of splines to center of u-joint bore
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Cardone – Front Drive Shaft: Not Greasable, Direct Replacement (Part No.65-9442)

Front Drive Shaft: Not Greasable, Direct Replacement

from

$868.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100% dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100% NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100% dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
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Yukon Gear – Replacement Yoke For Dana 30, 44, 50, And 300 With 26 Spline And A 1310 U/Joint Size (Part No.41018)

Replacement Yoke For Dana 30, 44, 50, And 300 With 26 Spline And A 1310 U/Joint Size

from

$121.99
Yukon replacement yoke for Dana 30, 44, 50, and Dana 300 with 26 spline and a 1310 U/joint size. 3.219″ snap ring span, 1.062″ cap diameter. Outside snap ring. This yoke uses u-bolts. All Yukon yokes come with a one year warranty against manufacturing defects.

Product Features:
  • Fits Dana Spicer 44
  • 26 spline
  • 1310 u-joint size
  • 3.219″ snap ring span
  • 1.062″ cap diameter
  • Outside snap ring design
  • U-bolt style
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Yukon Gear – Replacement Yoke For Dana 30, 44, And 50 With 26 Spline And A 1350 U/Joint Size (Part No.41021)

Replacement Yoke For Dana 30, 44, And 50 With 26 Spline And A 1350 U/Joint Size

from

$289.99
Yukon replacement yoke for Dana 30, 44, and 50 with 26 spline and a 1350 U/joint size. 3.625″ snap ring span, 1.188″ cap diameter. Outside snap ring. This yoke uses straps. All Yukon yokes come with a one year warranty against manufacturing defects.

Product Features:
  • Fits Dana Spicer 30 and 44
  • 26 spline
  • 1350 u-joint size
  • Outside snap ring design
  • 3.625″ snap ring span
  • 1.188″ cap diameter
  • Strap style
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Carquest Premium – CV Axle Shaft Assembly (Part No.NCV11123)

CV Axle Shaft Assembly

from

$136.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
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MOOG – Axle Support Bushing (Part No.K202054)

Axle Support Bushing

from

$24.99
Axle Support Bushing

Dorman – Axle Support Bushing (Part No.905-540)

Axle Support Bushing

from

$32.49
This axle support bushing is precision-engineered and rigorously tested to provide reliable replacement for the original equipment on specific vehicles.

Product Features:
  • Direct replacement – fits and performs like the original equipment on specific vehicles
  • Reliable fit – precision-engineered to match the design and dimensions of original components
  • Durable construction – manufactured to strict standards using sturdy, safe materials
  • Rigorously tested – thorough quality control measures ensure longevity
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Drive Shafts and Axles Brands You Can Trust For Your Ford F-250 Pickup

16 trusted brands of Drive Shafts and Axles line our shelves, ready to help keep your Ford F-250 Pickup running smooth. Below are some of the most popular brands and their top Drive Shafts and Axles offerings:

Popular Dorman Drive Shafts and Axles

Dorman products for the Ford F-250 Pickup span several categories. Some of the highest-rated Dorman Drive Shafts and Axles that will fit your Ford F-250 Pickup are:
Rear Axle Differential Vent
from $9.49
(6)
Rear Axle Differential Vent
Axle Vents
Driveshaft Flange Bolts
from $20.29
(1)
Driveshaft Flange Bolts
Drive Shaft Support Bolts

Top Ford F-250 Pickup Drive Shafts and Axles from National

Your Ford F-250 Pickup will be purring again thanks to National brand Drive Shafts and Axles available for online order or in-store pick up. Popular National parts include:
Bearings
from $16.99
(39)
Bearings
Axle Shaft Bearings
Multi Purpose Bearing
from $44.99
(25)
Multi Purpose Bearing
Drive Shaft Center Supports
Multi Purpose Seal
from $14.99
(20)
Multi Purpose Seal
Axle Shaft Seals

Most Purchased Ford F-250 Pickup Drive Shafts and Axles from Spicer

When you buy the most frequently purchased Spicer brand Drive Shafts and Axles, you can be confident it will be the right part for your Ford F-250 Pickup. Here are the Spicer Drive Shafts and Axles Advanced Auto customers buy the most:
Universal Joint
from $51.99
(7)
Universal Joint
Axle Shaft Universal Joints
Multi Purpose Bearing
from $73.99
(17)
Multi Purpose Bearing
Drive Shaft Center Supports
Universal Joint
from $40.99
(10)
Universal Joint
Axle Shaft Universal Joints

FAQs for Ford F-250 Pickup Drive Shafts and Axles

What are the most purchased Drive Shafts and Axles for the Ford F-250 Pickup?

Out of 115 Drive Shafts and Axles for the Ford F-250 Pickup, the most popular in our inventory are:
Multi Purpose Seal
from $10.99
(19)
Multi Purpose Seal
Axle Shaft Seals
Universal Joint
from $51.99
(7)
Universal Joint
Axle Shaft Universal Joints
Universal Joint
from $40.99
(10)
Universal Joint
Axle Shaft Universal Joints

What are the top-rated Ford F-250 Pickup Drive Shafts and Axles?

Top-rated Drive Shafts and Axles for your Ford F-250 Pickup based on customer reviews/ratings are:
CV Axle Shaft Assembly
from $136.99
(41)
CV Axle Shaft Assembly
“Nice fit”
Wheel Bearing: Direct Fit, 1 Piece
from $52.99
(20)
Wheel Bearing: Direct Fit, 1 Piece
“USA made”
Multi Purpose Bearing
from $73.99
(17)
Multi Purpose Bearing
“Muy bueno y se ajusto como si fuera original”