2022 Ford F-250 Super Duty Drivetrains

Essential 2022 Ford F-250 Super Duty Drivetrains

Yukon Gear – 1330 U/Joint With Zerk Fitting (Part No.42002)

1330 U/Joint With Zerk Fitting

from

$51.99
Yukon 1330 U/Joint with zerk fitting. 3.625″ snap ring span, 1.062″ cap diameter. Outside snap ring.
See More

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (Part No.615-133.1)

Spindle Nut 2 In.-16 Hex Size 3 In.

from

$36.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

National – Multi Purpose Seal (Part No.710413)

Multi Purpose Seal

from

$23.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Dorman – Center Support Bearing (Part No.934-035)

Center Support Bearing

from

$189.99
This drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Motorcraft – 4WD Actuator Valve (Part No.J7603674059MTR)

4WD Actuator Valve

from

$69.89
4WD Actuator Valve

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$20.29
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Idemitsu – Type HK Automatic Transmission Fluid – 1 qt (Part No.10112-042D)

Type HK Automatic Transmission Fluid - 1 qt

from

$10.79
Engineered for and meets requirements of Hyundai/Kia/Mitsubishi Automatic Transmission with SP-III specifications.

Product Features:
  • Excellent resistance to oxidation and thermal breakdown provides long fluid life and extended protection
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Provides superior cleanliness, keeping the transmission free of sludge and varnish deposits
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
  • Advanced anti-wear technology provides maximum protection to gears and bearings
See More

Dorman – Rear Drive Shaft: Greaseable, Adjustable (Part No.946-404)

Rear Drive Shaft: Greaseable, Adjustable

from

$1174.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Yukon Gear – Right Hand Axle Assembly For ’05-’12 Ford "Super 60" F250/F350 Front, With Stub Axle Seal (Part No.21753)

Right Hand Axle Assembly For '05-'12 Ford "Super 60" F250/F350 Front, With Stub Axle Seal

from

$664.99
Product Features:
  • 35 spline
  • Fits Super Dana Spicer 60 in 2010-2011 Ford F250 and F350
  • Right hand side
See More

Dorman – Front Axle Shaft Kit with Universal Joint, 1541H (Part No.630-435)

Front Axle Shaft Kit with Universal Joint, 1541H

from

$624.99
Axle shaft damaged or bearings worn out? This axle shaft assembly directly replaces the original equipment on certain vehicles, ready for install right out of the box.

Product Features:
  • Direct replacement – this axle shaft assembly replaces the original equipment on specific vehicle years, makes and models
  • Ready to install – comes pre-assembled for simple installation with no further assembly required
  • Durable construction – designed to rigorous standards and tested to ensure performance
  • Trustworthy solution – backed by team of engineers and quality control specialists in the United States
See More

Dorman – Rear Axle O-Ring Kit (Part No.926-163)

Rear Axle O-Ring Kit

from

$16.29
The axle shaft o-ring seals the rear axle to the wheel hub. The symptom of a failed axle shaft o-ring is an axle fluid leak around wheel hub. This is an ideal repair solution to prevent axle fluid leaks from forming around the wheel hub.

Product Features:
  • Aftermarket exclusive replacement part
  • Recommended for replacement when servicing vehicle brakes
  • Direct replacement for original equipment
  • This part has undergone extensive vehicle try-on and durability testing to ensure strength, fitment and longevity
See More

National – Multi Purpose Seal (Part No.710825)

Multi Purpose Seal

from

$91.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

USA Standard Gear – Ring/Pinion Sets (Part No.58057)

Ring/Pinion Sets

from

$289.99
Ring/Pinion Sets

USA Standard Gear – Master Overhaul Kit for ’08-’10 Ford 10.5" Differentials Using OEM Ring & Pinion. (Part No.37099)

Master Overhaul Kit for '08-'10 Ford 10.5" Differentials Using OEM Ring & Pinion.

from

$589.99
USA Standard Master Overhaul kits let you finish your install with confidence. This kit uses Koyo bearings and races. Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), threading locking compound, marking compound with brush and gasket. .

Product Features:
  • Fits 2008-2010 Ford 10.5″ housing with OEM ring and pinion set
  • Uses Koyo bearings and races
  • Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve, thread locker, marking compound with brush and gasket.
See More

Spicer – Axle Shft Univ Joint (Part No.SPL55-4X)

Axle Shft Univ Joint

from

$102.99
Axle Shft Univ Joint

Spicer – Universal Joint (Part No.5-178X)

Universal Joint

from

$42.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.
See More

Milemarker – MileMarker Supreme; Manual Hub (Part No.449S/S)

MileMarker Supreme; Manual Hub

from

$428.99
Ultimate in style and service. Latest patented technology. Smooth operation. Limited lifetime warranty. 10 spline, 6 bolts. Chrome.

Product Features:
  • Ultimate In Style And Service
  • Latest Patented Technology
  • Smooth Operation
  • Limited Lifetime Warranty
See More

Dorman – Manual Locking Hub Assembly (Part No.600-220)

Manual Locking Hub Assembly

from

$164.99
Four-wheel drive malfunctioning due to a bad locking hub? This locking hub directly replaces the original equipment hub on specific vehicles years, makes and models.

Product Features:
  • Direct replacement – this locking hub matches the fit and function of the original equipment hub on specific vehicles
  • Effective fix – replacement restores 4WD operation after original equipment hub fails
  • Thoroughly tested – vehicle try-on testing and rigorous quality control measures ensure longevity
  • Trustworthy quality – backed by team of designers and engineers in the United States
See More

Spicer – Differential Seal (Part No.J7040444357SPI)

Differential Seal

from

$67.75
Differential Seal

Timken – Axle Shaft Seal (Part No.K4021473864TIM)

Axle Shaft Seal

from

$45.90
Timken understands how important seals are in the automotive industry. Leveraging our knowledge and experience with bearings, we offer a broad line of light-duty oil seals made exclusively for Timken in some of the world’s most advanced manufacturing plants.

Product Features:
  • Machined rubber sealing edge provides greater accuracy and consistency, as well as a better sealing surface.
  • The flanged design allows for easier and proper installation and helps avoid cocking.
  • The latex bore coat seals the outer diameter leak path and helps compensate for minor bore imperfections.
  • Extra dust lip helps keep harmful contaminants, such as dirt, out of the bearing and protects against rust and corrosion.
See More

National – Bearings (Part No.387A)

Bearings

from

$22.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Driveworks – Tapered Cup Wheel Bearing Assembly (Part No.S-LM-102910)

Tapered Cup Wheel Bearing Assembly

from

$8.49
Value-priced bearing meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

Yukon Gear – RngPnnKt (Part No.24709)

RngPnnKt

from

$584.99
RngPnnKt

Yukon Gear – RngPnnKt (Part No.24766)

RngPnnKt

from

$779.99
RngPnnKt

Yukon Gear – Hardcore Diff Cover For Dana 50, Dana 60 & Dana 70 (Part No.32352)

Hardcore Diff Cover For Dana 50, Dana 60 & Dana 70

from

$288.99
Product Features:
  • Nodular iron for added strength
  • Thick design
  • Durable powder coat finish
  • Magnetic drain plug
  • Made in USA
  • High strength stainless steel fasteners
See More

ATP – DIFF COVER KIT (Part No.111105)

DIFF COVER KIT

from

$61.99
DIFF COVER KIT

National – Multi Purpose Seal (Part No.100712V)

Multi Purpose Seal

from

$30.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: springless; single-lip
  • Temperature range: -100°F to 450°F; -73°C to 232°C
  • Resistant to hydrocarbon/oxygenate blends and provides superior performance
  • Provides excellent dry running capabilities, low coefficient of friction and excellent resistance to chemicals
  • Delivers quality and reliable performance for every type of repair
See More

Motive Gear – Differential Pinion Seal (Part No.5778)

Differential Pinion Seal

from

$9.49
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

2022 Ford F-250 Super Duty Drivetrains

You count on your 2022 Ford F-250 Super Duty to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Drivetrains. With 34 Drivetrains ranging in price from $12.79 to $789.99, you’re sure to find everything you need for your 2022 Ford F-250 Super Duty.

Brands matter. If you want to shop a specific Drivetrains brand, we stock 11 different brands like Valvoline, Spicer, and Royal Purple. 2022 Ford F-250 Super Duty Drivetrains start as low as $12.79!

One of the best ways to find top quality OEM or aftermarket Drivetrains is by asking professionals. Short of that, you can shop with confidence thanks to our 2,490 extensive product reviews on 2022 Ford F-250 Super Duty Drivetrains. Some of the top-rated Drivetrains products we carry are Universal Joint with 3.9 stars and Multi Purpose Seal with 5.0 stars.

Did we mention you can order your Drivetrains from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Drivetrains inventory for your 2022 Ford F-250 Super Duty below to get started!

Top-Rated Drivetrains Brands For Your 2022 Ford F-250 Super Duty

Trusted Drivetrains OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2022 Ford F-250 Super Duty running right for years to come. In our inventory you’ll find brands like Valvoline, Spicer, Royal Purple, and even more.

Popular Dorman – Help Drivetrains

You’ll find popular Dorman – Help brand products across Drive Shafts and Axles. All are waiting to get your 2022 Ford F-250 Super Duty back on the road. Some of the top-rated Dorman – Help products in these categories are:
Driveshaft Flange Bolts
from $20.29
(1)
Driveshaft Flange Bolts
Drive Shaft Support Bolts

FAQs for 2022 Ford F-250 Super Duty Drivetrains

What are the most purchased Drivetrains for the 2022 Ford F-250 Super Duty?

Out of 34 Drivetrains for the 2022 Ford F-250 Super Duty, the most popular in our inventory are:
Max Automatic Transmission Fluid (1 Quart)
from $19.49
(30)
Max Automatic Transmission Fluid (1 Quart)
Differential Oil
Universal Joint
from $40.99
(10)
Universal Joint
Axle Shaft Universal Joints
Universal Joint
from $51.99
(1)
Universal Joint
U-Joints

What are the top-rated 2022 Ford F-250 Super Duty Drivetrains?

Top-rated Drivetrains for your 2022 Ford F-250 Super Duty based on customer reviews/ratings are:
Universal Joint
from $81.99
(7)
Universal Joint
“Spicer is the best U Joint you can buy there is no better.”
Multi Purpose Seal
from $12.99
(3)
Multi Purpose Seal
“quality seal that replaced the motorcraft version for a better price on my 2005 f250”