2022 Ford E-350 Super Duty Ignition and Tune-Up Products

Name: High-Durability Spark Plug: Reduces Misfires & Fuel Consumption
Brand: Motorcraft
SKU: SP-526-X
Price: 10.99 USD

Below you will find various in-demand Ford Ignition and Tune-Up Products, components and accessories for your 2022 E-350 Super Duty. Advance Auto Parts has popular E-350 Super Duty parts like Ignition Boots, Spark Plugs, Ignition Switches and more. You’ll also find aftermarket and OEM Ignition and Tune-Up Products for other E-350 Super Duty model years including 2014, 2015, 2016, 2017, 2018, 2019, 2021, 2023, 2024 and more. Select a category of 2022 Ford E-350 Super Duty Ignition and Tune-Up Products below and start saving instantly.

Popular 2022 Ford E-350 Super Duty Ignition and Tune-Up Products Categories

Ignition Starter Switches

Essential Ignition and Tune-Up Products for 2022 Ford E-350 Super Duties

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$10.99

Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles, engineered to meet strict Ford engineering standards for performance and reliability. These spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption, and optimize emissions. They are resistant to oxidation and arc erosion, feature a multi-rib insulator to protect against misfire, and offer service intervals of up to 100,000 miles. Backed by Motorcraft’s Service Parts Warranty, these spark plugs are an exact fit for Ford, Lincoln, and Mercury vehicles and are designed with high-quality materials to provide reliable performance for almost any application. Motorcraft ignition components also help prevent false check engine lights, ensuring your vehicle runs smoothly.

Product Features:

Motorcraft spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption and optimize emissions.
Backed by Motorcraft’s Service Parts Warranty
Exact fit for Ford, Lincoln and Mercury vehicles
Resistant to oxidation and arc erosion.
Multi-rib insulator protects against misfire.
Service intervals of up to 100,000 miles.
Motorcraft Spark Plugs are designed with high quality materials to provide reliable performance for almost any application.
Motorcraft Spark Plugs are what was in the vehicle when it was manufactured
Motorcraft ignition components help prevent false check engine lights.
Engineered for Ford Vehicles: Motorcraft High-Durability Spark Plugs are original equipment on Ford, Lincoln, and Mercury vehicles, ensuring a perfect fit and optimal performance.

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$9.10

Spark Plug

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$4.79

With over 100 years of engineering expertise and more than 11 billion plugs sold, Autolite delivers unmatched reliability. Designed and engineered in the USA, these spark plugs feature a high nickel alloy side electrode that maintains a precise gap and a full platinum tip that ensures virtually no gap erosion for extended life. The necked-down center electrode fires quicker and cleaner with less voltage, providing easier starts, quicker acceleration, and improved fuel economy compared to standard plugs. The tapered seat type further enhances performance and durability.

Product Features:

High nickel alloy side electrode maintains precise gap
Full platinum tip assures virtually no gap erosion for long life
Necked-down center electrode fires quicker, cleaner with less voltage for easier starts, quicker acceleration and improved fuel economy (as compared to standard plugs)
Tapered Seat Type: Enhances performance and durability for a longer-lasting spark plug.

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$6.79

Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, Autolite Double Platinum spark plugs feature platinum-to-platinum firing which virtually eliminates gap erosion, reduces misfires and increases durability of the plug. Consider upgrading to Autolite Iridium XP spark plugs for increased performance.

Product Features:

Works to optimize engine performance for a longer life and improved fuel economy
OE design
Full-platinum tips; platinum on both the center and side electrodes to promote reduced gap wear
Platinum ball welding process provides a consistent point of contact for enhanced adhesion

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$6.99

The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.53 is a 14mm, .708 reach plug with a taper seat. It fits domestic applications, and is widely available in automotive retail stores. The automotive plugs have three legs securing the Diamond Fire electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond Fire side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:

E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
The Spark Plugs are pre-gapped at the factory and cannot be adjusted.

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$99.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:

Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.

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$62.99

CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

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$30.49

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$40.99

High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:

Designed to OE standards for ease of installation
Copper alloy conductors ensure superior electrical conductivity with low resistive losses
Our parts are 100% tested to verify both mechanical and electrical switching performance
Robust design and high grade materials meet the stringent demands of today’s service professional
BWD is a global manufacturer of original equipment ignition products, complete quality control is maintained through the manufacturing process from componentry to finished product

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$92.40

Ignition Switch

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$21.79

Motorcraft Ignition Boots are engineered to provide original equipment performance and reliability. All Motorcraft parts undergo rigorous lab and real-world tests in order to meet strict Ford engineering standards. Terminal ends are designed to help ensure they do not separate from the cable under normal service conditions. High dialectic insulation helps maintain and control voltage delivery while reducing radio frequency interference. The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles

Product Features:

Backed by Motorcraft’s Service Parts Warranty
Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
Motorcraft ignition components help prevent false check engine lights.

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$49.99

CARQUEST Premium coil on plug boots are engineered to restore ignition boot reliability and performance. We have OE design providing an exact direct fit for your application and the performance and durability meet or exceed OE requirements. It offers excellent heat resistance as well as maximum protection against spark loss. With durable silicone compound for resistance to high heat or abrasion.

Product Features:

Provides excellent heat resistance as well as maximum protection against spark loss.
Durable silicone compound for resistance to high heat or abrasion
Spring included with the coil boot
Design for direct compatibility
OE design provides an exact fit for your application
Multipack provides one time replace all COP for better deal

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$51.99

Pc Cop Boots 97-11 Ford 8-Cyl

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$7.49

NGK Coil on Plug Boots are built to stringent OEM tolerances, combining original equipment fit, design and outstanding durability. NGK Coil on Plug Boots are manufactured using only high temperature, premium silicone and always include any required internal springs and ferrite resistors for superior performance and RFI noise suppression. Bridging the important link between ignition coil and spark plug, COP boots should always be replaced with NGK Coil on Plug Boots at the time as changing spark plugs to prevent ignition problems such as flashover.

Product Features:

IMPROVED HIGH TEMPERATURE DESIGN: Solves melting problems for certain very high heat applications
OEM MATCHED: Includes all required internal springs and ferrite resistors for superior performance and RFI noise suppression

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$42.49

MSD Street Fire coils will improve the performance of your late model GM or Ford vehicle. The E-core dual connector and TFI coils feature epoxy-filled construction and 48,000 maximum volts. They mount directly in place of the factory coil and accept the factory connectors for an easy installation.

Product Features:

Increased Spark Energy Over The Entire RPM Range Of The Engine
Coils Bolt In Place Of The Factory Units
Accepts OEM Connections For A Simpler Installation

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$80.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles. Motorcraft and Ford Parts are used throughout Ford vehicles in a variety of applications that help ensure the proper build quality, integrity and long-lasting performance of every Ford car or truck. Motorcraft and Ford Parts are manufactured from first quality materials chosen specifically for maximum performance and application suitability. As with all Motorcraft and Ford Parts, any innovations or improvements developed since the vehicle’s manufacture are included in these after market replacement parts, ensuring the most current technology and performance.

Product Features:

These coils provide the exact spark timing that helps maximize the engine and emissions performance
RFI suppression helps minimize electronic noise through a Ford patented spring assembly inside the coil boot
Engineered to help withstand temperature extremes
Internal insulation displacement connection is helps make high-reliability internal connections
Interior insulation helps ensure no internal arcing
Right fit for each application; helps provide ease of installation and removal
High grade silicone rubber boot materials do not degrade or stick, aiding in environmental and dielectric sealing
Housings engineered to help resist cracking in the most extreme conditions
Ford-patented iron core lamination stack integrates rare earth magnets in the flux circuit to help deliver consistent high energy required for output

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$153.99

NGK ignition coils are manufactured to meet or exceed OE standards for the highest durability and operational performance, so they can be installed with confidence. NGK and their family of automotive products have over 80 year’s experience and are driven by extreme dedication to innovation, performance and quality. Developed and rigorously tested in our ISO 17025 accredited test lab under the most extreme conditions, NGK’s coil designs will outperform all others – far beyond operational environments a vehicle would actually experience

Product Features:

OE QUALITY: Vacuum-sealed premium epoxy resin and thermoplastic coil housings provide superior dielectric strength, voltage insulation and durability
OPTIMAL PERFORMANCE: Precision coil windings and laminations maximize outputs, custom NGK ASIC chipset optimizes efficiency, prevents component damage
EASE OF INSTALLATION: NGK Ignition Coils include ignition control module, premium high temperature coil boot, and jumper harnesses where required
THE NGK DIFFERENCE: Featuring superior materials and design enhancements.
EXTENSIVE TESTING: NGK ignition coils must pass extreme testing during manufacturing to ensure the highest quality and durability standards are met
PRODUCT ENGINEERING: Advanced flow and stress modeling systems preemptively identify and avoid common failure points found in OE and competitor coils

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$55.99

Carquest ignition coils meet original equipment (OE) fit, form and function and are built to ensure reliable starting and performance. Carquest ignition coils are tested to ensure proper spark and perfect fit for each application. These ignition coils are an affordable repair choice to restore the vehicle’s ignition system performance.

Product Features:

Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
100% pure copper precision-wound windings increase coil life and ensure reliability and maximum coil output when needed.
Highly conductive aluminum alloy secondary terminal guarantees secondary coil terminals will not oxidize (rust), will provide excellent conductivity, extended coil life and will not cause excessive stress on the primary control circuit.
100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
100% end-of-line tested to ensure confidence and product reliability, every time.

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$59.05

Driveworks offers a line of aftermarket parts and accessories that are commercially acceptable and competitively priced, which provides professional technicians and DIYers with an affordable alternative for repairs.

Product Features:

Direct-fit OE replacement ensures ease of installation
Designed to meet OE performance
As the leader in commercially acceptable parts, we provide professional technicians with the quality parts they need
As the leader in commercially acceptable parts, we provide professional technicians with the quality parts they need

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$24.99

ACCEL Super Coils feature advanced bobbin technology, highly specialized silicon magnetic steel cores, optimized windings, proper resistance and engineered turn ratios that deliver a high performance, quality coil. Specialized high temperature epoxy resists shock and vibration, while increasing thermal conductivity. These are direct improved performance replacements for OEM coils.

Product Features:

Specialized silicone magnetic steel cores are surrounded by precision wrapped windings using advanced bobbin technology which helps maintain the proper resistance and turn ratios necessary to deliver improved performance spark
Advanced Bobbin Technology
Direct Plug In Replacement results in a Direct OE Fit
OBD ll Safe, so you won’t be throwing codes, just sparks
Standard Motor Products SMP Fd-503
MSD 8242 82428
Resists Shock And Vibration
Resists Corrosion

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$299.99

Carquest Premium ignition coil sets meet or exceed original equipment (OE) specifications and are developed by top OE/OES manufacturers to ensure superior performance. All of our Carquest Premium ignition coil sets are developed by IATF 16949 certified manufacturers for consistent durability and long-lasting performance. These ignition coils use high-quality components and will utilize optimized designs on applications where the OE ignition coil had frequent failures. We require stringent testing standards to ensure proper fit and performance for each application and stand behind our Carquest Premium ignition coil sets with an industry-leading warranty. Carquest Premium ignition coil sets are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Built by IATF 16949 certified manufacturers for consistent durability
Coil drivers match OE for current limit, electrostatic discharge (ESD) protection and multi-spark
Segmented secondary bobbins to distribute high voltage and prevent shorting
Extensive design validation testing to ensure long-lasting reliability
100% end-of-line tested to ensure proper performance
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

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$61.30

The Forecast OE quality knock sensor is engineered to the exact specifications of the vehicle manufacturer to ensure the replacement sensor is the same in quality and function as the part installed as first equipment.

Product Features:

OEM quality direct fit application
Ground-isolated design with two-wire shielded harness helps protect the sensor signal from electro-magnetic interference (EMI)
Mounting hole is the same size as OE
Maintains OE specifications for frequency response

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$36.99

Building upon a foundation of premium full-line products established under NGK ignition and NTK oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand: NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. NTK is the only OE supplier with a full-line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, NTK sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. NTK sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:

Reinforced and extra-strength components are used to reduce chance of part failure and prevent corrosion and moisture penetration. Mounting threads match OE for easy, worry free installation.
NTK’s Ignition Knock Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function to ensure proper ignition timing. This advanced technology is used for durability, drivability and fuel economy.
The Ignition Knock (Detonation) Sensor monitors vibrations caused by engine knock, or detonation, to alter the ignition timing and prevent detonation.

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$23.99

Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

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$33.99

MotoRad Knock Sensors respond to a wide range of engine knock frequencies providing accurate engine condition to the ECM for optimal ignition timing. Highest quality piezoceramic element manufactured to tight tolerances for increased durability. All MotoRad Knock Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:

Precision piezoceramic element ensures accurate response to a wide range of engine vibrations
Manufactured using the highest quality OEM materials to ensure optimal performance and rugged durability
Designed to meet or exceed all OEM specifications in fit, form & function
Extensive product testing includes salt spray, high/low temperature impact, thermal cycling, vibration, drop among other tests, to ensure all sensors meet or exceed OEM specifications.

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$28.99

Bosch OE quality knock sensors for optimum engine protection and fuel consumption reduction up to 9%.

Product Features:

Bosch OE quality knock sensors for optimum engine protection
Bosch OE quality knock sensors increase torque up to 5%
Bosch OE quality knock sensors enable the use of multiple quality fuels with various anti-knock properties

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$39.99

Encore Automotive Genuine OE knock sensor detects excessive/unusual pulses caused by the engine ignition and makes proper adjustments to reduce the risk of damaging pistons. Encore Automotive is dedicated to bringing the latest original equipment technologies to the Aftermarket to provide the highest overall value.

Product Features:

Genuine OE Part
Highly accurate engine vibration detection
Excellent material quality

Upgrade your 2022 Ford E-350 Super Duty with Top-Quality Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2022 Ford E-350 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Ignition and Tune-Up Products are key to keeping your E-350 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 15 Ignition and Tune-Up Products for the 2022 Ford E-350 Super Duty, designed to meet your needs without breaking the bank. From Ignition Boot replacements to Spark Plugs upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Ignition and Tune-Up Products for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Ignition and Tune-Up Products for your 2022 Ford E-350 Super Duty at great prices. Our Ignition and Tune-Up Products inventory for this model ranges from just $7.99 to $258.18, with an average price of $62.02. Our 15 Ignition and Tune-Up Products in stock come from 6 trusted brands, so you’re sure to find the right part for your 2022 Ford E-350 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2022 Ford E-350 Super Duty, we stock popular OEM and aftermarket Ignition and Tune-Up Products from top names like NGK, Motorcraft, E3, and more. NGK Ignition and Tune-Up Products start at just $13.99 and boast an impressive 5 stars average rating from customers. Motorcraft and E3 also bring quality to the table, with Ignition and Tune-Up Products available starting at $7.99, and at an average 5 stars rating. With 178 customer reviews and counting, our 2022 Ford E-350 Super Duty Ignition and Tune-Up Products have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Ignition and Tune-Up Product upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2022 Ford E-350 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your E-350 Super Duty in top shape, all in one place. Start shopping confidently below for your 2022 Ford E-350 Super Duty!

Best-Selling Ignition Boots for 2022 Ford E-350 Super Duties

Enhance the driving experience in your Ford with 1 quality Ignition Boot components, starting at $21.79.

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$21.79

Backed by Motorcraft’s Service Parts Warranty
Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
Motorcraft ignition components help prevent false check engine lights.

Most Popular 2022 Ford E-350 Super Duty Spark Plugs

Customize your Ford with 7 Spark Plugs products like Spark Plugs, all priced under $14.79.

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$14.79

NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug; Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:

HIGH IGNITABILITY PROJECTED SQUARE PLATINUM ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with a unique cut-back PSPE ground electrode
RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
PSPE DESIGN: Projected square platinum electrode shape of the ground electrode provides the best ignitability and service life for high heat engines
SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
RECOMMENDED USAGE: Modern vehicles using OE PSPE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
Enhanced Fuel Burn: Provides a more complete fuel burn, resulting in quicker throttle response, smoother idle, and better cold starts.
Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.

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$8.49

The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:

E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.

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$13.99

NGK Laser Platinum spark plugs provide high ignitability and longer service life compared to conventional nickel spark plugs. Laser Platinum plugs are tested to the highest standards to ensure quality and durability. Engineered specifically for OE applications. Laser platinum plugs provide stable idling, superior anti-fouling, improved fuel efficiency and lower emissions. High-grade pure alumina ceramic and 98% pure copper core prevents spark plug from overheating and provides reliable starts. Most Laser Platinum spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:

ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire platinum alloy center electrode provides consistent performance
PLATINUM ALLOY CENTER ELECTRODE: Longer wearing and higher temperature resistance compared to traditional nickel spark plugs
PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
RECOMMENDED USAGE: Best for vehicles with OE fine wire platinum alloy plugs

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$13.24

DENSO Iridium Power spark plugs represent a performance breakthrough. The laser-welded center electrode is only 0.4mm in diameter – the slimmest iridium electrode in the industry. The taper-cut side electrode complements the design, delivering reliable spark energy under the most gruelling pressures and temperatures. DENSO engineers used the power of this miraculous metal to produce an iridium center electrode that is only 0.4mm in diameter. With its superior thermal qualities, this whisker-fine electrode is capable of taking the most extreme heat and punishment. This breakthrough was matched to one of DENSO’s most famous innovations, the patented U-Groove ground electrode. The combination of these two features resulted in the Iridium Power® plug, one of the most advanced and innovative spark plugs on the market.

Product Features:

Tapered cut, U-Groove ground electrode
0.4mm iridium center electrode
360-degree laser welding assembly process
Required ignition voltage reduced
Unsurpassed center electrode durability
Available for many performance and power sports applications, including Corvette, Viper, and Harley-Davidson The Iridium Power plug delivers greater spark energy while demanding significantly less secondary required voltage from the ignition system.

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$9.33

Motorcraft Original Equipment Platinum Iridium spark plugs are designed, engineered and recommended by Ford Motor Company.

Product Features:

Same part installed when the engine rolled off the assembly line
100,000-mile service interval
Platinum ball on the center electrode minimizes gap erosion for longer life
Proprietary platinum ball welding process provides a consistent point of contact for better adhesion
Fewer misfires and reduced gap erosion
Optimizes engine performance to provide improved fuel economy

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$9.10

Spark Plug

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$7.99

Engineered for superior ignition performance, the Motorcraft High-Performance Spark Plug is designed to optimize fuel efficiency and ensure reliable starts. Crafted with precision, this spark plug offers exceptional durability and consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance. Upgrade to Motorcraft and experience the difference in your engine’s responsiveness and fuel economy.

Product Features:

Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.

Top Picks for 2022 Ford E-350 Super Duty Ignition Switches

Upgrade Ford E-350 Super Duties with top-quality Ignition Switches parts, including 4 OEM and aftermarket selections for your 2022 model.

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$70.99

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$83.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:

Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.

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$99.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:

Direct-fit, OE replacement parts – identical to factory installed parts. Robust design helps provide long operating life and excellent performance.
All OE switch functions are maintained. Factory connectors help ensure a solid, positive connection. Provided factory mounting points ensure easy installation – new gaskets and attaching hardware is included, where applicable.

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$92.40

Ignition Switch

In-Demand Ignition Sensors for 2022 Ford E-350 Super Duties

Select from 1 premium Ignition Sensors parts for your 2022 Ford E-350 Super Duty.

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$23.99

Most Sold 2022 Ford E-350 Super Duty Ignition Coils and Boots

Explore our best-selling Ford parts for the 2022 E-350 Super Duty among 2 OEM and aftermarket options starting from $201.99.

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$258.18

DIRECT IGNITION COIL

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$201.99

Ignition Coil

Top-Rated Ignition and Tune-Up Products Brands For Your 2022 Ford E-350 Super Duty

Shop for the best-rated brands offering Ignition and Tune-Up Products and other products for your 2022 Ford E-350 Super Duties. Below you’ll find some of our best rated Ignition and Tune-Up Products from NGK, Motorcraft, and E3, and more. Ignition and Tune-Up Products from these brands that fit a 2022 E-350 Super Duty start at just $7.99 and are rated as high as 5 stars. OEM and aftermarket Ignition and Tune-Up Products don’t get more top quality, durable, and affordable than from the brands below.

Popular NGK 2022 Ford E-350 Super Duty Ignition and Tune-Up Products

When it comes to maintaining or upgrading your 2022 Ford E-350 Super Duty, using quality Ignition and Tune-Up Products is essential to ensure durability and a perfect fit. NGK ticks all of those boxes. We offer a wide selection of NGK Ignition and Tune-Up Products, specifically designed for the 2022 Ford E-350 Super Duty. With over 2 NGK brand Ignition and Tune-Up Products in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $13.99, with an average price of just $14.39. Plus, with over 1 customer reviews and an average rating of 5 stars, you can trust that our NGK Ignition and Tune-Up Products will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

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$14.79

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Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX

“I got these for my 2019 Mustang Ecoboost and these were way better spark plugs then anything i have tried definitely a performance oriented, spark plu”

from
$13.99

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OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13

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Popular Motorcraft 2022 Ford E-350 Super Duty Ignition and Tune-Up Products

Motorcraft auto parts is one of the highest quality Ignition and Tune-Up Product brands in the market. Any 2022 Ford E-350 Super Duty owner should feel confident when installing genuine Motorcraft parts in their vehicle. To ensure the best fit and performance for your 2022 E-350 Super Duty, Advance Auto Parts carries a full inventory of 7 Motorcraft Ignition and Tune-Up Products. Plus you will be keeping your Ford in peak condition while saving money because prices on these Motorcraft Ignition and Tune-Up Products range from $7.99 to $99.99, plus, with more than 1 customer reviews and an impressive 5 stars average rating, you can be confident the Fram Ignition and Tune-Up Products below will deliver on both quality and value.

from
$92.4

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Ignition Switch

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from
$83.99

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Original Equipment (O.E.) Switch Assembly – Ignition

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from
$99.99

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Original Equipment (O.E.) Switch Assembly – Ignition

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FAQs for 2022 Ford E-350 Super Duty Ignition and Tune-Up Products

Which Ignition and Tune-Up Products are best-sellers for 2022 Ford E-350 Super Duties?

Out of 15 Ignition and Tune-Up Products that fit 2022 Ford E-350 Super Duties, the following parts are the top sellers:

Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (11333712) – $21.79
OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13 (12101952) – $13.99
Ignition Switch (12493863) – $70.99

What’s the price range for 2022 Ford E-350 Super Duty Ignition and Tune-Up Products?

Ignition and Tune-Up Product prices for the 2022 Ford E-350 Super Duty start at $7.99 and go up to $258.18 for the most premium parts.

What’s the average price of a Ignition and Tune-Up Product for a 2022 Ford E-350 Super Duty?

The average price for Ignition and Tune-Up Products for the 2022 Ford E-350 Super Duty is $62.02. Keep in mind the variety of part types within our Ignition and Tune-Up Product category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Ignition and Tune-Up Products for other Ford E-350 Super Duty model years?

Yes, we currently carry Ignition and Tune-Up Products for 24 model years of Ford E-350 Super Duties between 2000 and 2025. Ignition and Tune-Up Products are bought most frequently for the following model years: 2023, 2024, 2021, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Ignition and Tune-Up Products for my 2022 Ford E-350 Super Duty?

The cheapest 2022 Ford E-350 Super Duty Ignition and Tune-Up Products we carry in stock are:

High-Performance Spark Plug: Enhances Fuel Efficiency (50011448) – $7.99
DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (11333297) – $8.49
Spark Plug (12614208) – $9.10
Original Equipment Platinum Iridium Spark Plug (11582582) – $9.33
Iridium Power Spark Plug (10746371) – $13.24

What are the top-rated Ignition and Tune-Up Products that fit the 2022 Ford E-350 Super Duty?

Out of 178 reviews by customers, our 2022 Ford E-350 Super Duty Ignition and Tune-Up Products have an average customer rating of . These are some of the highest-rated Ignition and Tune-Up Product types for the 2022 Ford E-350 Super Duty and their top-rated products:

Spark Plugs
- Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (12069657) – $14.79
- DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (11333297) – $8.49

What types of Ignition and Tune-Up Products do you sell for my 2022 Ford E-350 Super Duty?

As of 2/5/25, these are some of the most in-demand types of Ignition and Tune-Up Products for a 2022 Ford E-350 Super Duty:

Can I get help with 2022 Ford E-350 Super Duty Ignition and Tune-Up Product orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Ignition and Tune-Up Products and more.

What is your return policy for Ford E-350 Super Duty Ignition and Tune-Up Products?

Advance Auto Parts keeps returns simple. For new Ford E-350 Super Duty Ignition and Tune-Up Products and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2022 Ford E-350 Super Duty Ignition and Tune-Up Products

Motorcraft – High-Durability Spark Plug: Reduces Misfires & Fuel Consumption (Part No.SP-526-X)

Motorcraft – Spark Plug (Part No.F10003269731MTR)

Autolite – Platinum Spark Plug: Fires Cleaner, Easier Starts, Quicker Acceleration (Part No.AP103)

Autolite – Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (Part No.APP103)

E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.53)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6573)

Carquest Premium – Ignition Switch (Part No.CSC3797)

Carquest Premium – Ignition Switch (Part No.CSA1262)

Carquest – Ignition Switch (Part No.CS942)

Motorcraft – Ignition Switch (Part No.M5050485141MTR)

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Carquest Premium – Coil On Plug Insulator Boot Multi Pack, Spring included (Part No.38-001FMP)

Accel – Pc Cop Boots 97-11 Ford 8-Cyl (Part No.128041)

NGK – Coil on Plug Boot (Part No.59022)

MSD Ignition – Coil; Street Fire; Ford 4.6/5.4L 2-Valve 98-14 Single (Part No.5512)

Motorcraft – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.DG-508)

NGK – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.48761)

Carquest – Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece (Part No.26C1001)

Driveworks – Ignition Coil (Part No.26326)

Accel – High-Performance Ignition Coils for Ford 2-Valve Engines (Part No.140032)

Carquest Premium – Ignition Coil Set: Meets or Exceeds OE Specifications, 8 Count (Part No.EBC1342-8)

Forecast – Forecast Knock Sensor (Part No.F6020200559FOR)

NTK – Ignition Knock (Detonation) Sensor (Part No.ID0141)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBC3679)

Bosch – Knock Sensor (Part No.0261231316)

Encore Automotive – Genuine OE Ignition Knock (Detonation) Sensor (Part No.SKS-D20005)

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

NGK – Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (Part No.95605)

E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

NGK – OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13 (Part No.94862)

DENSO – Iridium Power Spark Plug (Part No.F1000312474ND)

Motorcraft – Original Equipment Platinum Iridium Spark Plug (Part No.F1000411669MTR)

Motorcraft – Spark Plug (Part No.F10003269731MTR)

Motorcraft – High-Performance Spark Plug: Enhances Fuel Efficiency (Part No.SP-589)

Carquest Premium – Ignition Switch (Part No.CSC1044)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6958)

Motorcraft – Original Equipment (O.E.) Switch Assembly – Ignition (Part No.SW-6573)

Motorcraft – Ignition Switch (Part No.M5050485141MTR)

Carquest Premium – Ignition Knock (Detonation) Sensor (Part No.SBA3805)

Worldpac – DIRECT IGNITION COIL (Part No.F30053386988MTR)

Carquest Premium – Ignition Coil (Part No.EBA2001)