2022 Ford E-350 Super Duty Drivetrains

Name: Universal Joint
Brand: Spicer
SKU: 5-1410X
Price: 51.99 USD
Rating: 5.0 (1 reviews)

Below you will find various in-demand Ford Drivetrains, components and accessories for your 2022 E-350 Super Duty. Advance Auto Parts has popular E-350 Super Duty parts like Universal Joints, Transfer Cases, Differentials and more. You’ll also find aftermarket and OEM Drivetrains for other E-350 Super Duty model years including 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2021 and more. Select a category of 2022 Ford E-350 Super Duty Drivetrains below and start saving instantly.

Popular 2022 Ford E-350 Super Duty Drivetrains Categories

Differential Oil

Axle Shaft Universal Joints

Drive Shaft Support Bolts

U-Joints

Drive Shaft Center Supports

Center Support Bearings

Input Shaft Bearings

Differential Pinion Seals

Spindle Lock Nuts

Rear Differential Pinion Bearings

Differential Carrier Bearings

Axle Nuts

Essential Drivetrains for 2022 Ford E-350 Super Duties

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$51.99

You expect a lot from your vehicle, and Spicer Life Series (SPL) universal joints deliver. SPL universal joints consistently outperform competitors, so you can hit the road or trail with confidence. Check out the difference that SPL universal joints can make in your vehicle, and make sure you’re getting the longer life, increased bearing capacity and lower maintenance costs that Spicer Life Series (SPL) can provide.

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$40.99

When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.

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$40.99

Spindle nut for Dana 70, 1.940″ I.D., 6 slots. This replaces Spicer part number 33732.

Product Features:

Spindle nut for Dana Spicer 70, 70U and 70HD
1.940″ I.D.
6 slots

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$36.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$39.49

Center support bearings or Carrier Support Bearings are used when the driveshaft is split into two sections. It serves as a junction on the drive shaft between the transmission and the differential allowing the driveshaft to flex, relieving stress on other drive line components. Each part is engineered and designed to OE Standards. Applicable to CHEV 60-02; DODGE 64-66; FORD 75-15; GMC 60-02;. Please verify your application.

Product Features:

MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
For Years: 1960-2015
Weight approx: 3 Lbs
BEARING ID / BORE: 1.5750 INCH / 40 MM
CENTERLINE: 2.28 INCH / 58 MM
MOUNT WIDTH: 6.62 INCH / 168 MM
NO STUDS

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$89.23

Driveshaft Support

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$99.99

Redline Synthetic “Shock Proof” Oil. 3 Quarts.

Product Features:

Includes three quarts of Redline Shockproof oil

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$14.99

Valvoline Multi-Vehicle Transfer Case Fluid is a full synthetic product meeting the performance needs for transfer cases recommending Ford XL-12 and GM Auto Trak II specifications or ATF fluids (DEX/MERC, ATF +4, etc).

Product Features:

Recommended for use in most Ford, GM and FCA (Dodge, Jeep) models
Formulated to help prevent gear wear and protect against rust and corrosion
Formulated to deliver enhanced protection against deposits
Helps provide better protection during extreme operating conditions

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$20.29

This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$9.99

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Crowned raceways and rollers to ensure even load distribution for maximum life
Industry leading coverage
Professional technicians know they can depend on National

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$24.99

All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!

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$23.99

National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:

Low swell in hydrocarbon fluids
Design type: spring loaded; multi-lip
Provides good low temperature capability
Temperature range: -40°F to 225°F; -40°C to 107°C
Delivers quality and reliable performance for every type of repair

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$11.99

Product Features:

Brand may vary by location

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$51.84

Spindle Nut

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$3.93

Dorman’s Spindle Nut is manufactured for high corrosion resistance and a long service life. Depending on the application, it is also available in a kit that includes the nut, washer, and retainer.

Product Features:

Direct replacement for a proper fit every time
High quality steel construction
Conveniently available in many styles and in packs of different quantities
Dorman’s Spindle Nuts are constructed to strict engineering quality standards

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$29.49

Drive Shaft Center Support

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$57.83

The Timken Driveshaft Support is an ideal high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:

Premium Original Equipment replacement
Provides performance and dependability
Manufactured to meet OE specifications

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$73.99

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Controlled heat treating process for lasting performance and extended bearing life
Industry leading coverage
Professional technicians know they can depend on National

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$7.19

Universal Joint

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$41.99

Backed by superior materials and rigorous testing, MOOG Super Strength universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:

BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
CORROSION PROTECTION — Exclusive MICRO SHIELDΓ┐ó coating protects against rust and corrosion
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability

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$53.99

1330 Yukon Lifetime U/Joint. 3.625″ snap ring span, 1.062″ cap diameter. Outside snap ring.

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$60.23

SKF is a supplier of original equipment wheel bearings, hubs and seals to most of the world’s leading automakers. Engineered and manufactured to the highest quality standards, SKF wheel bearings greatly reduce friction and increase load-carrying capabilities. With an ability to boost reliability under heavy loads and misaligned conditions, SKF wheel bearings offer an ideal solution for many wheel end applications.

Product Features:

Precision bearing pre-load and correct application of advanced manufacturing techniques such as orbital rolling
100% tested to the actual OE specifications per part number for fit, form and function
High quality steel and surface finishes
Proper implementation of heat treatment

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$264.99

Set-up carrier bearing kti (2 bearings, no races) for Dana 70 HD and Dana 80. 469. No return.

Product Features:

Set up bearing kit
Fits Dana Spicer 80
Easily slips on and off carrier journals to allow for easier carrier shim adjustment

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$276.99

Set-up carrier bearing kit (2 bearings, no races) for Dana 60 and 70. 387A. No return.

Product Features:

Set up bearing kit
Fits Dana Spicer 60
Easily slips on and off carrier journals to allow for easier carrier shim adjustment

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$16.99

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Crowned raceways and rollers to ensure even load distribution for maximum life
Industry leading coverage
Professional technicians know they can depend on National

Upgrade your 2022 Ford E-350 Super Duty with Top-Quality Drivetrains

When it comes to maintaining or upgrading your 2022 Ford E-350 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Drivetrains are key to keeping your E-350 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 31 Drivetrains for the 2022 Ford E-350 Super Duty, designed to meet your needs without breaking the bank. From Universal Joint replacements to Transfer Cases upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2022 Ford E-350 Super Duty at great prices. Our Drivetrains inventory for this model ranges from just $3.49 to $83.99, with an average price of $32.17. Our 31 Drivetrains in stock come from 11 trusted brands, so you’re sure to find the right part for your 2022 Ford E-350 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2022 Ford E-350 Super Duty, we stock popular OEM and aftermarket Drivetrains from top names like Valvoline, Moog, Driveworks, and more. Valvoline Drivetrains start at just $12.49 and boast an impressive 5 stars average rating from customers. Moog and Driveworks also bring quality to the table, with Drivetrains available starting at $15.99, and at an average 4 stars rating. With 581 customer reviews and counting, our 2022 Ford E-350 Super Duty Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2022 Ford E-350 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your E-350 Super Duty in top shape, all in one place. Start shopping confidently below for your 2022 Ford E-350 Super Duty!

Best-Selling Universal Joints for 2022 Ford E-350 Super Duties

Enhance the driving experience in your Ford with 10 quality Universal Joint components, starting at $15.99.

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$55.99

Backed by superior materials and rigorous testing, MOOG Super Strength® universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:

BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
CORROSION PROTECTION — Exclusive MICRO SHIELD coating protects against rust and corrosion
STRONG AND DURABLE — Cold-forged, case-hardened and precision-ground alloy steel crosses for durability
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
GREASABLE DESIGN — Bearing cups feature a radial design to allow 360 Degrees lubricant distribution to all bearing surfaces
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates

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$28.99

Backed by superior materials and rigorous testing, MOOG Premium universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:

COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
GREASABLE DESIGN — Greasable u-joints allow for new grease to flush out contaminants and moisture
KEEPS DIRT OUT — Nitrile rubber grease seals use a compressed double lip design for effective protection against contaminants
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability
Cross forging shape and flash provide easier installation and high strength

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$36.99

BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
CORROSION PROTECTION — Exclusive MICRO SHIELD coating protects against rust and corrosion
STRONG AND DURABLE — Cold-forged, case-hardened and precision-ground alloy steel crosses for durability
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
GREASABLE DESIGN — Bearing cups feature a radial design to allow 360 Degrees lubricant distribution to all bearing surfaces
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates

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$15.99

DRIVEWORKS Universal Joints are designed to meet or exceed OE fit, form, and function. These universal joints are set to provide superior quality and easy installation. DRIVEWORKS Universal Joints are constructed from quality materials for extended durability. DRIVEWORKS Universal Joints are pre-lubricated with premium grease to provide a longer service life. The grease fittings are pre-installed to allow for easy maintenance (where applicable).

Product Features:

The cross is hot forged for the higher torque and horsepower
The bearing cups are made by cold forging, having higher strength and better rigidity
Bearig cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
Lubrication grooves designed to ensure grease penetration to entire journal and needle bearings
Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
Snap rings are held to strict tolerances to ensure proper cup position and retention
Nitrile rubber seals to optimize grease retention and reduce contamination

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$41.99

BUILT TO LAST — Rugged design specifically engineered for applications with higher torque and horsepower
COMPREHENSIVE COVERAGE — Available for foreign and domestic nameplates
CORROSION PROTECTION — Exclusive MICRO SHIELDΓ┐ó coating protects against rust and corrosion
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on
STRONG AND DURABLE — Bearing cups are cold-forged, case-hardened and precision ground while steel cross is forged and carburized heat treated for strength and durability

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$19.99

Backed by superior materials and rigorous testing, MOOG Heavy Duty universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:

BUILT TO LAST — Rugged design specifically engineered for fleets, off-highway and commercial vehicles
STRONG AND DURABLE — Bearing cups are cold-formed, case-hardened and precision ground for strength and durability
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
GREASEABLE DESIGN — Drilled and tapped grease fitting holes for easy servicing and cross trunnions with large grease reservoirs with radial grease channels for grease distribution
INHIBITS PREMATURE WEAR — Cross trunnions ground to a 15-25 RMS finish for a smooth surface free of microscopic grooves that can cause premature wear
RELIABLE PERFORMANCE — Internal anti-drainback valve integrated into thrust washer controls lubrication flow and prevents dry startup
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on

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$15.99

The cross is hot forged for the higher torque and horsepower
The bearing cups are made by cold forging, having higher strength and better rigidity
Bearig cups allow 360 lubricant distribution to bearing surfaces, and are precision-ground for maximum load-carrying capabilities
Lubrication grooves designed to ensure grease penetration to entire journal and needle bearings
Grease fitting in the cross allows for easy maintenance and the flexible use of the whole assembly
Snap rings are held to strict tolerances to ensure proper cup position and retention
Nitrile rubber seals to optimize grease retention and reduce contamination

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$32.60

Designed and built by GMB to handle the highest loads and excessive torque found in pickups, SUVs, 4x4s and off road vehicles.

Product Features:

Elliptical bearing design delivers reliable performance under the heaviest of loads
Exclusive GMB Ultra-select bearing design exceeds OE specification
Precision finish trunnions and bearing surfaces ensure durability
Proven reliability in off-road conditions and harsh environments

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$49.21

Spicer Drivetrain Products light-duty U-joints feature journal crosses that are manufactured from high-quality alloy forgings and heat-treated for maximum life. The bearing cups are case-hardened for strength and durability, while the seals are crafted from nitrile rubber for optimum grease retention and contaminant exclusion. Ample grease reservoirs in each trunnion assure effective lubrication; they’re pre-filled with high-quality synthetic lithium grease, providing superior friction-reduction and resistance to higher temperatures. These replacement universal joints are available for dozens of positions, as well as greasable and non-greasable styles. Order the model designed for fitment with your vehicle and engine type.

Product Features:

Forged cross
Lubeable
O.E.M replacement
Snap rings

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$24.18

U Joint

Top Picks for 2022 Ford E-350 Super Duty Differentials

Upgrade Ford E-350 Super Duties with top-quality Differentials parts, including 7 OEM and aftermarket selections for your 2022 model.

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$14.49

Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, and Allison C-4.

Product Features:

Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
Enhanced anti-shudder protection for smooth shifting and maximum power transfer
Developed with anti-wear technology to help improve transmission durability
Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures

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$69.99

Valvoline SAE 75W-140 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our formulation provides exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity and wear resistance, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. It’s recommended for conventional rear axles and transmissions requiring EP gear lubes under high speed, high load, high torque and high horsepower conditions.

Product Features:

EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -22F to 390F degrees
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5

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$9.99

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Crowned raceways and rollers to ensure even load distribution for maximum life
Industry leading coverage
Professional technicians know they can depend on National

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$19.99

We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-140 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-140 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:

FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations
EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5

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$60.23

Precision bearing pre-load and correct application of advanced manufacturing techniques such as orbital rolling
100% tested to the actual OE specifications per part number for fit, form and function
High quality steel and surface finishes
Proper implementation of heat treatment

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$18.91

Pinion Seal

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$12.49

Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:

HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions

In-Demand Drive Shafts and Axles for 2022 Ford E-350 Super Duties

Select from 9 premium Drive Shafts and Axles parts for your 2022 Ford E-350 Super Duty, with prices ranging from $3.93 to $83.99.

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from

$40.99

from

$20.29

Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

from

$51.99

from

$39.49

MAXIMUM VIBRATION DAMPENING: Rubber cushion is made of high grade rubber that ensures maximum dampening of vibration and the ability to absorb over loads.
HEAVY GAUGE STEEL FRAME: The housing frame is made from heavy gauge steel with durability that extends the service life.
READY TO INSTALL: Most center supports include a sealed bearing and dust shield and are ready to install.
For Years: 1960-2015
Weight approx: 3 Lbs
BEARING ID / BORE: 1.5750 INCH / 40 MM
CENTERLINE: 2.28 INCH / 58 MM
MOUNT WIDTH: 6.62 INCH / 168 MM
NO STUDS

from

$17.26

Spindle Nut

from

$83.99

Center Support Bearing

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$57.83

The Timken Driveshaft Support is an ideal high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:

Premium Original Equipment replacement
Provides performance and dependability
Manufactured to meet OE specifications

from

$55.99

Universal Joint

from

$3.93

Direct replacement for a proper fit every time
High quality steel construction
Conveniently available in many styles and in packs of different quantities
Dorman’s Spindle Nuts are constructed to strict engineering quality standards

Most Sold 2022 Ford E-350 Super Duty Spindles

Explore our best-selling Ford parts for the 2022 E-350 Super Duty among 4 OEM and aftermarket options starting from $3.49.

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from

$3.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

from

$3.99

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

from

$36.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

from

$36.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

Top-Rated Drivetrains Brands For Your 2022 Ford E-350 Super Duty

Shop for the best-rated brands offering Drivetrains and other products for your 2022 Ford E-350 Super Duties. Below you’ll find some of our best rated Drivetrains from Valvoline, Moog, and Driveworks, and more. Drivetrains from these brands that fit a 2022 E-350 Super Duty start at just $12.49 and are rated as high as 5 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.

Popular Valvoline 2022 Ford E-350 Super Duty Drivetrains

When it comes to maintaining or upgrading your 2022 Ford E-350 Super Duty, using quality Drivetrains is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Drivetrains, specifically designed for the 2022 Ford E-350 Super Duty. With over 4 Valvoline brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $12.49, with an average price of just $29.24. Plus, with over 366 customer reviews and an average rating of 5 stars, you can trust that our Valvoline Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

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$12.49

This product is not rated

High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart

“”

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$14.49

(2)

DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

“I’ve used this in my 2005 2500HD since I bought the truck with 20k on it now at 280k changed every other year maybe 40k I’d put on in two years,
I pu”

from
$19.99

This product is not rated

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart

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Popular Moog 2022 Ford E-350 Super Duty Drivetrains

Moog auto parts is one of the highest quality Drivetrain brands in the market. Any 2022 Ford E-350 Super Duty owner should feel confident when installing genuine Moog parts in their vehicle. To ensure the best fit and performance for your 2022 E-350 Super Duty, Advance Auto Parts carries a full inventory of 5 Moog Drivetrains. Plus you will be keeping your Ford in peak condition while saving money because prices on these Moog Drivetrains range from $19.99 to $55.99, plus, with more than 143 customer reviews and an impressive 4 stars average rating, you can be confident the Fram Drivetrains below will deliver on both quality and value.

from
$55.99

(39)

Greaseable Super Strength Universal Joint

“u joint works well.”

from
$28.99

(20)

Greaseable Premium Universal Joint

“Fit perfect no issues”

from
$36.99

(41)

Greaseable Super Strength Universal Joint

“Easy install and great way to have sting durability with access to grease points”

FAQs for 2022 Ford E-350 Super Duty Drivetrains

Which Drivetrains are best-sellers for 2022 Ford E-350 Super Duties?

Out of 31 Drivetrains that fit 2022 Ford E-350 Super Duties, the following parts are the top sellers:

Greaseable Super Strength Universal Joint (10086981) – $55.99
Greaseable Super Strength Universal Joint (10086947) – $36.99
Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart (12507272) – $19.99

What’s the price range for 2022 Ford E-350 Super Duty Drivetrains?

Drivetrain prices for the 2022 Ford E-350 Super Duty start at $3.49 and go up to $83.99 for the most premium parts.

What’s the average price of a Drivetrain for a 2022 Ford E-350 Super Duty?

The average price for Drivetrains for the 2022 Ford E-350 Super Duty is $32.17. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drivetrains for other Ford E-350 Super Duty model years?

Yes, we currently carry Drivetrains for 24 model years of Ford E-350 Super Duties between 2000 and 2025. Drivetrains are bought most frequently for the following model years: 2021, 2019, 2018, 2017, 2016, 2015, 2014, 2013, and 2012.

What are the cheapest Drivetrains for my 2022 Ford E-350 Super Duty?

The cheapest 2022 Ford E-350 Super Duty Drivetrains we carry in stock are:

Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (21260547) – $3.49
Axle Spindle Nut (11480768) – $3.93
Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (sold by each) (22149122) – $3.99
Bearings (3272400) – $9.99
High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart (11301050) – $12.49

What are the top-rated Drivetrains that fit the 2022 Ford E-350 Super Duty?

Out of 581 reviews by customers, our 2022 Ford E-350 Super Duty Drivetrains have an average customer rating of . These are some of the highest-rated Drivetrain types for the 2022 Ford E-350 Super Duty and their top-rated products:

Universal Joints
- Greaseable Super Strength Universal Joint (10086981) – $55.99
- Greaseable Premium Universal Joint (10086907) – $28.99
- Universal Joint (10265721) – $15.99
Differentials
- Greaseable Super Strength Universal Joint (10086981) – $55.99
- Greaseable Premium Universal Joint (10086907) – $28.99
- Universal Joint (10265721) – $15.99
Spindles
- Greaseable Super Strength Universal Joint (10086981) – $55.99
- Greaseable Premium Universal Joint (10086907) – $28.99
- Universal Joint (10265721) – $15.99

What types of Drivetrains do you sell for my 2022 Ford E-350 Super Duty?

As of 2/5/25, these are some of the most in-demand types of Drivetrains for a 2022 Ford E-350 Super Duty:

Can I get help with 2022 Ford E-350 Super Duty Drivetrain orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Drivetrains and more.

What is your return policy for Ford E-350 Super Duty Drivetrains?

Advance Auto Parts keeps returns simple. For new Ford E-350 Super Duty Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2022 Ford E-350 Super Duty Drivetrains

Spicer – Universal Joint (Part No.5-1410X)

Spicer – Universal Joint (Part No.5-160X)

Yukon Gear – Spindle Nut For Dana 70, 1.940" I.D., 6 Slots (Part No.33479)

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (Part No.615-133.1)

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6053)

SKF – Driveshaft Support (Part No.K10301069521SKF)

Yukon Gear – Redline Synthetic "Shock Proof" Oil – 3 Quarts (Part No.15000)

Valvoline – Transfer Case Fluid, 1 Quart (Part No.855459)

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

National – Bearings (Part No.15245)

Motive Gear – Differential Pinion Seal (Part No.6808N)

National – Multi Purpose Seal (Part No.719316)

Driveworks – Differential Pinion Seal (Part No.S-719316)

Dorman – Spindle Nut (Part No.K1002831714DOR)

Dorman – Axle Spindle Nut (Part No.K4030212888DOR)

Driveworks – Drive Shaft Center Support (Part No.S-HB-88508-A)

Timken – Driveshaft Support with Bearing (Part No.K1030195244TIM)

National – Multi Purpose Bearing (Part No.HB-88508-A)

Neapco – Universal Joint (Part No.2-0054)

MOOG Driveline Products – Non-Greaseable Super Strength Universal Joint (Part No.231)

Yukon Gear – 1330 Lifetime U/Joint (Part No.42004)

SKF – Wheel Bearing (Part No.K8000205983SKF)

Yukon Gear – Set Up Bearing (Part No.56040)

Yukon Gear – Set Up Bearing (Part No.56039)

National – Bearings (Part No.15101)

MOOG Driveline Products – Greaseable Super Strength Universal Joint (Part No.295)

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.330)

MOOG Driveline Products – Greaseable Super Strength Universal Joint (Part No.232)

Driveworks – Universal Joint (Part No.DW-331)

MOOG Driveline Products – Non-Greaseable Super Strength Universal Joint (Part No.231)

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.331)

Driveworks – Universal Joint (Part No.DW-330)

GMB – Universal Joint – Greasable (Part No.K1010481404GMB)

Spicer – Lube For Life Non Greasable U-Joint (Part No.K1010991370SPI)

Autopart International Inc – U Joint (Part No.K10101976375API)

National – Bearings (Part No.15101)

Valvoline – DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.822405)

Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon (Part No.887344)

National – Bearings (Part No.15245)

Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart (Part No.889787)

SKF – Wheel Bearing (Part No.K8000205983SKF)

SKF – Pinion Seal (Part No.J7010201578SKF)

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart (Part No.VV820)

Spicer – Universal Joint (Part No.5-160X)

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Spicer – Universal Joint (Part No.5-1410X)

Anchor – Center Support Bearing Motor Mount: Center, 1 Piece (Part No.6053)

Dorman – Spindle Nut (Part No.K1002831650DOR)

Spicer – Center Support Bearing (Part No.211359X)

Timken – Driveshaft Support with Bearing (Part No.K1030195244TIM)

Spicer – Universal Joint (Part No.5-1410-1X)

Dorman – Axle Spindle Nut (Part No.K4030212888DOR)

Dorman – Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (Part No.615-072.1)

Dorman – Standard Spindle Nut 3/4 In.-16 Hex Size 1-1/16 In. (sold by each) (Part No.615-072)

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (sold by each) (Part No.615-133)

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (Part No.615-133.1)