2021 Lexus RX350 Drivetrains

Essential 2021 Lexus RX350 Drivetrains

NOK – Drive Axle Seal (Part No.J7043570758NOK)

Drive Axle Seal

from

$17.88
Drive Axle Seal

Ishino Stone – TRANS CASE OUTPUT SF (Part No.J7121452626ISH)

TRANS CASE OUTPUT SF

from

$8.50
TRANS CASE OUTPUT SF

National – Multi Purpose Seal (Part No.710870)

Multi Purpose Seal

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
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National – Multi Purpose Seal (Part No.710807)

Multi Purpose Seal

from

$25.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
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Dorman – Spindle Nut M22-1.50 Hex Star Pattern (sold by each) (Part No.615-224)

Spindle Nut M22-1.50 Hex Star Pattern (sold by each)

from

$8.49
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Driveshaft Center Support Bearing (Part No.934-405)

Driveshaft Center Support Bearing

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$94.99
This drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Driveshaft Center Support Bearing (Part No.934-404)

Driveshaft Center Support Bearing

from

$95.99
This drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles
  • Restores functionality – this bearing is made to fit and fully restore part functionality after the original bearing fails
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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SKF – Driveshaft Support with Bearing (Part No.K1030158090SKF)

Driveshaft Support with Bearing

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$228.02
Rugged SKF drive shaft support bearings are built to meet or exceed OE specifications. They are also built on the years of experience that SKF has earned designing and supplying bearings to the world’s largest OE manufacturers. Engineered and manufactured to specific application requirements that deliver precise drive shaft alignment and support. Center support bearings are pre-lubricated and sealed with metal reinforced seals to prevent contamination. Rubber support cushions are manufactured from durable rubber compounds that provide maximum support while isolating the driveline shaft from damaging vibration. Drive shaft support frames are constructed from high quality steel or aluminum that provides additional strength and long life in harsh environments.

Product Features:
  • OE Quality, fit and performance
  • Precise driveshaft alignment and support
  • Pre-lubricated and sealed
  • Metal reinforced seals to prevent contamination
  • Manufactured from durable rubber compounds
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Valvoline – VAL EP ATF 6/1 QT (Part No.899179)

VAL EP ATF 6/1 QT

from

$14.99
VAL EP ATF 6/1 QT

Idemitsu – Type HP Automatic Transmission Fluid – 1 qt (Part No.30040099-75000C)

Type HP Automatic Transmission Fluid - 1 qt

from

$13.79
Formulated to meet the specific requirements of Subaru vehicles equipped with conventional (non-CVT) transmissions up to model year 2005. Recommended for service-fill in all Subaru automatic transmissions where SUBARU ATF HP is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Provides superior cleanliness, maintaining the transmission free of sludge and varnish deposits
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
  • Advanced anti-wear technology provides maximum protection to gears and bearings
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Valvoline – Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.820681)

Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$36.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON®, GM DEXRON®-II and DEXRON®-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III , Toyota/Lexus Type T, T-III and T-IV , Honda/Acura ATF-Z1 (except in CVTs) , Mercedes Benz NAG1 , Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Cardone – Rear Drive Shaft: Not Greasable, Direct Replacement (Part No.65-5036)

Rear Drive Shaft: Not Greasable, Direct Replacement

from

$1257.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100% dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100% NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100% dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
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Dorman – Rear Drive Shaft (Part No.946-164)

Rear Drive Shaft

from

$1185.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
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Dorman – Rear Drive Shaft: Adjustable (Part No.976-535)

Rear Drive Shaft: Adjustable

from

$1676.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
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Cardone – Rear Drive Shaft: Not Greasable, Direct Replacement (Part No.65-5008)

Rear Drive Shaft: Not Greasable, Direct Replacement

from

$1169.99
CARDONE Remanufactured Prop Shafts are engineered using the most stringent quality processes to deliver smooth, consistent performance in any driving condition. Original designs are scrutinized for potential improvement, and where applicable, design upgrades are implemented to produce a more durable part than the original. All critical components are tested to ensure proper function. Additionally, all CARDONE Prop Shafts are 100% dynamically balanced, resulting in vibration-free performance at all speeds.

Product Features:
  • Built to match O.E. form, fit and function.
  • 100% NEW universal joints are installed to ensure proper fit and optimal performance.
  • All slip yokes are lubricated to prevent premature wear.
  • Units are 100% dynamically balanced at 3200 RPMs for vibration-free operation and increased joint life.
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NSK – Wheel Hub Assembly (Part No.K7001455126NSK)

Wheel Hub Assembly

from

$225.99
NSK guarantees the high quality of all of their products by repeated, rigorous bench testing, and other checks that take full advantage of their cutting-edge technology, which only the major bearing manufacturers can offer. Double-row angular contact ball bearings with inner and outer mounting flange. NSK Hub unit bearings are designed to meet increasingly strict requirements that demand lighter weight, greater promotion of fuel efficiency, and enhanced module production systems. Double-row angular contact ball bearing with integral inner and outer mounting flange. Easier mounting due to preset preload.

Product Features:
  • Preset optimum preload with easy mounting process
  • High rigidity
  • Easy mounting process NSK offers compact and lightweight hub unit bearings with built-in ABS sensors
  • Integrated sensor rotor (encoder)
  • Compact size and lightweight achieved by utilizing active sensor
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FEQ – Wheel Hub Assembly (Part No.K7001176680FEQ)

Wheel Hub Assembly

from

$68.09
FEQ manufactures OE quality wheel hub assemblies that provide heavy duty performance, improved fuel economy and reduced weight. FEQ wheel bearing hubs are maintenance free – fully lubricated and sealed for life.

Product Features:
  • Integrated sensors and electronics for reliable function
  • Factory sealed assembly eliminates contamination
  • No need for pre-load adjustment at assembly
  • Compact and lightweight
  • Minimizes axial space requirements
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Carquest Premium – C/V Axle (Part No.NCV901911)

C/V Axle

from

$138.99
C/V Axle

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV69569)

CV Axle Shaft Assembly

from

$109.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
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Carquest Premium – CV Axle Shaft Assembly (Part No.NCV69500)

CV Axle Shaft Assembly

from

$109.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
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Carquest Premium – CV Axle Shaft Assembly (Part No.NCV519483)

CV Axle Shaft Assembly

from

$182.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

Carquest Premium – CV Axle Shaft Assembly (Part No.NCV517433)

CV Axle Shaft Assembly

from

$82.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.

Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% new axle and components
  • New axle nut or attaching hardware included when applicable
  • Bearings, races and housings are heat-treated for longer life
  • Precision-engineered seal mating surfaces for leak-free performance
  • High moly CV joint grease with stainless-steel boot bands
See More

EMPI – Axle Shaft Nut (Part No.K403059357EMP)

Axle Shaft Nut

from

$5.09
The EMPI Axle Shaft Nut is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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Dorman – Spindle Nut (Part No.K1002751713DOR)

Spindle Nut

from

$16.08
Spindle Nut

2021 Lexus RX350 Drivetrains

You count on your 2021 Lexus RX350 to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Drivetrains. With 9 Drivetrains ranging in price from $8.49 to $818.99, you’re sure to find everything you need for your 2021 Lexus RX350.

Brands matter. If you want to shop a specific Drivetrains brand, we stock 8 different brands like Dorman, Carquest Premium, and Valvoline. 2021 Lexus RX350 Drivetrains start as low as $8.49!

Did we mention you can order your Drivetrains from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Drivetrains inventory for your 2021 Lexus RX350 below to get started!

FAQs for 2021 Lexus RX350 Drivetrains

What are the most purchased Drivetrains for the 2021 Lexus RX350?

Out of 9 Drivetrains for the 2021 Lexus RX350, the most popular in our inventory are:
Spindle Nut M22-1.50 Hex Star Pattern (sold by each)
from $8.49
This product is not rated
Spindle Nut M22-1.50 Hex Star Pattern (sold by each)
Spindle Lock Nuts
CV Axle Shaft Assembly
from $182.99
This product is not rated
CV Axle Shaft Assembly
Drive Shaft and Axles
Spindle Nut
from $16.08
This product is not rated
Spindle Nut
Axle Nuts