2016 Lexus RX350 Drivetrains

Please Select your Vehicle to See Exact Fit Parts

Essential Drivetrains for 2016 Lexus RX350s

Anchor – Anchor Center Support Bearing Front, 6083 (Part No.6083)

Anchor Center Support Bearing Front, 6083

from

$109.99
Anchor 6083 Center support bearings support a driveshaft between transmission and differential. This mount relieves stress on driveline components. Each part is engineered and designed to OE Standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.
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Dorman – Dorman Driveshaft Center Support Bearing, 934-404 (Part No.934-404)

Dorman Driveshaft Center Support Bearing, 934-404

from

$105.99
This drive shaft center bearing is designed to match the fit and function of the original bearing on specified vehicles, and is engineered for durability and reliable performance.
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National – National Transfer Case Output Shaft Seal, 711075 (Part No.711075)

National Transfer Case Output Shaft Seal, 711075

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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National – National Transfer Case Output Shaft Seal, 710807 (Part No.710807)

National Transfer Case Output Shaft Seal, 710807

from

$26.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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National – National Shaft Repair Sleeve, 99215 (Part No.99215)

National Shaft Repair Sleeve, 99215

from

$48.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Shaft Repair Sleeve, 99166 (Part No.99166)

National Shaft Repair Sleeve, 99166

from

$36.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Shaft Repair Sleeve, 99210 (Part No.99210)

National Shaft Repair Sleeve, 99210

from

$49.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Differential Pinion Seal, 711098 (Part No.711098)

National Differential Pinion Seal, 711098

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Dorman – Dorman Spindle Nut M22-1.50 Hex Star Pattern (Sold by each), 615-224 (Part No.615-224)

Dorman Spindle Nut M22-1.50 Hex Star Pattern (Sold by each), 615-224

from

$11.99
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.
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National – National Drive Axle Shaft Seal, 711097 (Part No.711097)

National Drive Axle Shaft Seal, 711097

from

$22.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Carquest Premium – Carquest CV Axle Shaft Assembly, NCV519483 (Part No.NCV519483)

Carquest CV Axle Shaft Assembly, NCV519483

from

$196.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
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Carquest Premium – Carquest New CV Axle Shaft Assembly, NCV329863 (Part No.NCV329863)

Carquest New CV Axle Shaft Assembly, NCV329863

from

$131.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
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Carquest Premium – Carquest CV Axle Shaft Assembly, NCV69569 (Part No.NCV69569)

Carquest CV Axle Shaft Assembly, NCV69569

from

$119.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
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Carquest Premium – Carquest C/V Axle, NCV901911 (Part No.NCV901911)

Carquest C/V Axle, NCV901911

from

$151.99
Carquest C/V Axle, NCV901911. DRIVELINE – SHAFTS>SHAFTS & BOOT KITS>SHAFTS>CV SHAFTS – NEW from Carquest Premium
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Valvoline – Valvoline Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid 1 GA, 904891 (Part No.904891)

Valvoline Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid 1 GA, 904891

from

$35.99
Choosing an automatic transmission fluid just got easier. Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the #1 ATF product, is suitable for use in 95% of ATF vehicles in operation with US registered light duty applications. And now, it€™s also recommended for most belt and chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it€™s designed to help prevent leaks, reduce wear and tear, and maximize performance €“ all for much longer than conventional fluids. It has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Whether your vehicle has a CVT or traditional automatic, Valvoline MaxLife Multi-Vehicle ATF is suitable for a broad range of transmissions including Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW and Audi vehicles. It€™s specifically recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC. For the many miles ahead, trust your transmission with Valvoline, the #1 automatic transmission fluid brand.
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Valvoline – Valvoline Extended Protection Full Synthetic Automatic Transmission Fluid ATF 1 QT, 904976 (Part No.904976)

Valvoline Extended Protection Full Synthetic Automatic Transmission Fluid ATF 1 QT, 904976

from

$15.99
Modern transmissions are better than ever, with more gears to help improve fuel efficiency and acceleration. Greater performance calls for greater protection. Valvoline Extended Protection Full Synthetic ATF features our exclusive Dual Defense Additive Technology for two layers of protection against metal-on-metal contact and thermal breakdown, all while minimizing wear on clutch components. In fact, Valvoline Extended Protection Full Synthetic ATF is 45% stronger against breakdown compared to major brand DEX/MERC oxidative PDSC performance. Proven to maximize transmission life, our patented formula keeps your modern vehicle shifting smoothly, mile after mile, with the ultimate protection you can only expect from Valvoline, the #1 ATF brand.
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Dorman – Dorman Constant Velocity Axle Shaft Support Bearing Bracket, 926-193 (Part No.926-193)

Dorman Constant Velocity Axle Shaft Support Bearing Bracket, 926-193

from

$84.99
This CV axle support bearing matches the fit and function of the original equipment bearing to maintain proper support for the front axle. This support bearing replaces an original equipment part that may be worn or become damaged during service.
See More

National – National Shaft Repair Sleeve, 99147 (Part No.99147)

National Shaft Repair Sleeve, 99147

from

$42.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Upgrade your 2016 Lexus RX350 with Top-Quality Drivetrains

When it comes to maintaining or upgrading your 2016 Lexus RX350, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Drivetrains are key to keeping your RX350 functioning at its best. At Advance Auto Parts, we offer a wide selection of 17 Drivetrains for the 2016 Lexus RX350, designed to meet your needs without breaking the bank. From Spindle replacements to Drive Shafts and Axles upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2016 Lexus RX350 at great prices. Our Drivetrains inventory for this model ranges from just $11.99 to $196.99, with an average price of $76.98. Our 17 Drivetrains in stock come from 5 trusted brands, so you’re sure to find the right part for your 2016 Lexus RX350 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2016 Lexus RX350, we stock popular OEM and aftermarket Drivetrains from top names like National, and more. National Drivetrains start at just $42.49 and boast an impressive 4.3 stars average rating from customers. With 4 customer reviews and counting, our 2016 Lexus RX350 Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2016 Lexus RX350 is always ready to roll. We’re committed to providing you with everything you need to keep your RX350 in top shape, all in one place. Start shopping confidently below for your 2016 Lexus RX350!

Best-Selling Spindles for 2016 Lexus RX350s

Enhance the driving experience in your Lexus with 1 quality Spindle components, starting at $11.99.

Dorman – Dorman Spindle Nut M22-1.50 Hex Star Pattern (Sold by each), 615-224 (Part No.615-224)

Dorman Spindle Nut M22-1.50 Hex Star Pattern (Sold by each), 615-224

from

$11.99
This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.
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Most Popular 2016 Lexus RX350 Drive Shafts and Axles

Customize your Lexus with 9 Drive Shafts and Axles products like Drive Shaft and Axles, Axle Shaft Seals, and Center Support Bearings, all priced under $196.99.

National – National Shaft Repair Sleeve, 99147 (Part No.99147)

National Shaft Repair Sleeve, 99147

from

$42.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Carquest Premium – Carquest CV Axle Shaft Assembly, NCV519483 (Part No.NCV519483)

Carquest CV Axle Shaft Assembly, NCV519483

from

$196.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
See More

Carquest Premium – Carquest CV Axle Shaft Assembly, NCV905671 (Part No.NCV905671)

Carquest CV Axle Shaft Assembly, NCV905671

from

$114.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
See More

Anchor – Anchor Center Support Bearing Rear, Center, 6082 (Part No.6082)

Anchor Center Support Bearing Rear, Center, 6082

from

$121.99
Anchor 6082 Center support bearings support a driveshaft between transmission and differential. This mount relieves stress on driveline components. Each part is engineered and designed to OE Standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.
See More

National – National Drive Axle Shaft Seal, 711097 (Part No.711097)

National Drive Axle Shaft Seal, 711097

from

$22.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Carquest Premium – Carquest CV Axle Assembly, NCV69086 (Part No.NCV69086)

Carquest CV Axle Assembly, NCV69086

from

$183.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
See More

Carquest Premium – Carquest CV Axle Assembly, NCV69108 (Part No.NCV69108)

Carquest CV Axle Assembly, NCV69108

from

$127.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
See More

Carquest Premium – Carquest CV Axle Assembly, NCV69109 (Part No.NCV69109)

Carquest CV Axle Assembly, NCV69109

from

$126.99
Carquest Premium constant velocity (C.V.) axle shaft assemblies are 100% new units that are designed to meet or exceed OE specifications. Every part number is tested to guarantee a proper fit and reliable performance. Carquest Premium CV axles are assembled with a specially formulated high-temperature moly grease to resist friction and wear of the bearings and joints. Our strict engineering and quality specifications ensure a long-lasting repair that is guaranteed with an industry-leading warranty.
See More

Anchor – Anchor Center Support Bearing Front, 6083 (Part No.6083)

Anchor Center Support Bearing Front, 6083

from

$109.99
Anchor 6083 Center support bearings support a driveshaft between transmission and differential. This mount relieves stress on driveline components. Each part is engineered and designed to OE Standards. Natural and SBR rubber provide maximum life and performance. Steel fasteners are heat treated grade 5 bolts. A special bonding agent is used to ensure a rubber to metal bond. Rubber material is mixed to specific Durometer, hardness.
See More

Top Picks for 2016 Lexus RX350 CV Axles and Joints

Upgrade Lexus RX350s with top-quality CV Axles and Joints parts, including 1 OEM and aftermarket selections for your 2016 model.

Dorman – Dorman Constant Velocity Axle Shaft Support Bearing Bracket, 926-193 (Part No.926-193)

Dorman Constant Velocity Axle Shaft Support Bearing Bracket, 926-193

from

$84.99
This CV axle support bearing matches the fit and function of the original equipment bearing to maintain proper support for the front axle. This support bearing replaces an original equipment part that may be worn or become damaged during service.
See More

In-Demand Transfer Cases for 2016 Lexus RX350s

Select from 1 premium Transfer Cases parts for your 2016 Lexus RX350.

National – National Transfer Case Output Shaft Seal, 711075 (Part No.711075)

National Transfer Case Output Shaft Seal, 711075

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Most Sold 2016 Lexus RX350 Differentials

Explore our best-selling Lexus parts for the 2016 RX350 among 5 OEM and aftermarket options starting from $12.99.

National – National Shaft Repair Sleeve, 99166 (Part No.99166)

National Shaft Repair Sleeve, 99166

from

$36.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

National – National Shaft Repair Sleeve, 99210 (Part No.99210)

National Shaft Repair Sleeve, 99210

from

$49.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Valvoline – Valvoline Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid 1 GA, 904891 (Part No.904891)

Valvoline Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid 1 GA, 904891

from

$35.99
Choosing an automatic transmission fluid just got easier. Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the #1 ATF product, is suitable for use in 95% of ATF vehicles in operation with US registered light duty applications. And now, it€™s also recommended for most belt and chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it€™s designed to help prevent leaks, reduce wear and tear, and maximize performance €“ all for much longer than conventional fluids. It has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Whether your vehicle has a CVT or traditional automatic, Valvoline MaxLife Multi-Vehicle ATF is suitable for a broad range of transmissions including Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW and Audi vehicles. It€™s specifically recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC. For the many miles ahead, trust your transmission with Valvoline, the #1 automatic transmission fluid brand.
See More

Valvoline – Valvoline Extended Protection Full Synthetic Automatic Transmission Fluid ATF 1 QT, 904976 (Part No.904976)

Valvoline Extended Protection Full Synthetic Automatic Transmission Fluid ATF 1 QT, 904976

from

$15.99
Modern transmissions are better than ever, with more gears to help improve fuel efficiency and acceleration. Greater performance calls for greater protection. Valvoline Extended Protection Full Synthetic ATF features our exclusive Dual Defense Additive Technology for two layers of protection against metal-on-metal contact and thermal breakdown, all while minimizing wear on clutch components. In fact, Valvoline Extended Protection Full Synthetic ATF is 45% stronger against breakdown compared to major brand DEX/MERC oxidative PDSC performance. Proven to maximize transmission life, our patented formula keeps your modern vehicle shifting smoothly, mile after mile, with the ultimate protection you can only expect from Valvoline, the #1 ATF brand.
See More

National – National Differential Pinion Seal, 711098 (Part No.711098)

National Differential Pinion Seal, 711098

from

$12.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

Top-Rated Drivetrains Brands For Your 2016 Lexus RX350

Shop for the best-rated brands offering Drivetrains and other products for your 2016 Lexus RX350s. Below you’ll find some of our best rated Drivetrains from National, and more. Drivetrains from these brands that fit a 2016 RX350 start at just $42.49 and are rated as high as 4.3 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.

Popular National 2016 Lexus RX350 Drivetrains

When it comes to maintaining or upgrading your 2016 Lexus RX350, using quality Drivetrains is essential to ensure durability and a perfect fit. National ticks all of those boxes. We offer a wide selection of National Drivetrains, specifically designed for the 2016 Lexus RX350. With over 1 National brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $42.49. Plus, with over 2 customer reviews and an average rating of 4.3 stars, you can trust that our National Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
National Shaft Repair Sleeve, 99147
from $42.49
(2)
National Shaft Repair Sleeve, 99147
“Used this to repair a camshaft sealing surface on a 2000 Sienna. it worked incredibly well and was easy to use. My first time using a repair sleeve ”

FAQs for 2016 Lexus RX350 Drivetrains

Which Drivetrains are best-sellers for 2016 Lexus RX350s?

Out of 17 Drivetrains that fit 2016 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2016 Lexus RX350 Drivetrains?

Drivetrain prices for the 2016 Lexus RX350 start at $11.99 and go up to $196.99 for the most premium parts.

What’s the average price of a Drivetrain for a 2016 Lexus RX350?

The average price for Drivetrains for the 2016 Lexus RX350 is $76.98. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drivetrains for other Lexus RX350 model years?

Yes, we currently carry Drivetrains for 18 model years of Lexus RX350s between 2007 and 2026. Drivetrains are bought most frequently for the following model years: 2022, 2021, 2020, 2019, 2018, 2017, 2015, 2014, and 2013.

What are the cheapest Drivetrains for my 2016 Lexus RX350?

What types of Drivetrains do you sell for my 2016 Lexus RX350?

As of 8/2/26, these are some of the most in-demand types of Drivetrains for a 2016 Lexus RX350:

Can I get help with 2016 Lexus RX350 Drivetrain orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Drivetrains and more.

What is your return policy for Lexus RX350 Drivetrains?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.