2021 Ford F-250 Super Duty Drivetrains

Name: Differential Carrier Bearing Kit - Koyo
Brand: Motive Gear
SKU: R10.5CK
Price: 112.99 USD

Below you will find various in-demand Ford Drivetrains, components and accessories for your 2021 F-250 Super Duty. Advance Auto Parts has popular F-250 Super Duty parts like Universal Joints, Differentials, Drive Shafts and Axles and more. You’ll also find aftermarket and OEM Drivetrains for other F-250 Super Duty model years including 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2022 and more. Select a category of 2021 Ford F-250 Super Duty Drivetrains below and start saving instantly.

Popular 2021 Ford F-250 Super Duty Drivetrains Categories

Differential Oil

Axle Shaft Universal Joints

4WD Axle Actuator Housings

Drive Shaft Support Bolts

U-Joints

4WD Hubs

Differential Covers

Center Support Bearings

Drive and Prop Shaft Assemblies

Differential Bearings

Differential Axle Shafts

Axle Shaft Seals

Axle Spindle Seals

Differential Bearing Kits

Differential Pinion Seals

4WD Actuator Valves

Differential Ring and Pinions

Spindle Lock Nuts

Differential Carrier Bearings

Differential Seals

Essential Drivetrains for 2021 Ford F-250 Super Duties

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$112.99

Product Features:

CARRIER BEARING KIT FORD 10.5″

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$33.99

CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

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$20.29

This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$102.99

Axle Shft Univ Joint

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$397.99

aFe Power’s new rear differential cover brings performance engineering to the protection of your axles differential. This differential cover is constructed out of durable die cast aluminum with reinforced ribs and wrinkle black powder coating for maximum strength and styling. This cover comes with all necessary hardware and includes an O-ring for a leak free seal. This cover has about a 5 quart lube capacity at the factory line; factory cover holds about 4 quarts. Built-in internal and external fins transfer heat from the fluid to the outside air for maximum cooling. This system incorporates a large magnetic drain and fill plug that captures loose particles for maximum rear-end protection. Pre-installed large oil level sight glass with calibration plug set to the factory fluid level to eliminate overfilling.

Product Features:

External Fins Transfer Heat To Atmosphere
Internal Fins Absorb Heat From Lubricating Fluid
Magnetic Fill Plug
Magnetic Drain Plug

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$624.99

Axle shaft damaged or bearings worn out? This axle shaft assembly directly replaces the original equipment on certain vehicles, ready for install right out of the box.

Product Features:

Direct replacement – this axle shaft assembly replaces the original equipment on specific vehicle years, makes and models.
Ready to install – comes pre-assembled for simple installation with no further assembly required.
Durable construction – designed to rigorous standards and tested to ensure performance
Trustworthy solution – backed by team of engineers and quality control specialists in the United States

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$66.99

National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:

Low swell in hydrocarbon fluids
Design type: spring loaded; multi-lip
Provides good low temperature capability
Temperature range: -40°F to 225°F; -40°C to 107°C
Delivers quality and reliable performance for every type of repair

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$74.54

Differential Seal

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$234.09

Locking Hub

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$23.99

Low swell in hydrocarbon fluids
Design type: spring loaded; multi-lip
Provides good low temperature capability
Temperature range: -40°F to 225°F; -40°C to 107°C
Delivers quality and reliable performance for every type of repair

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$1243.99

Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:

Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
Serviceable construction – non-staked universal joints are designed for future serviceability

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$89.23

Driveshaft Support

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$35.99

Valvoline DEX/MERC ATF is a high-quality transmission fluid formulated to meet the challenging demands many automatic transmissions. Its responsive low-temperature fluidity is beneficial in both electronic and hydraulic controlled transmissions and transaxles. Recommended for use in the following applications: MERCON®, DEXRON®-III, Ford M2C138-CJ and M2C166-H, Allison C-4 and TES-389, and Caterpillar TO-2.

Product Features:

Formulated with premium base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
Enhanced anti-shudder protection for smooth shifting and maximum power transfer
Developed with anti-wear technology to help improve transmission durability
Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures

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$12.99

High Performance Motor Oil API LICENSED MOTOR OIL Royal Purple High Performance Motor Oil combines premium base oils with proprietary additive technologies to create a high performance synthetic engine oil that optimizes performance and protection. Royal Purple High Performance Motor Oils carry the current API and ILSAC engine oil licenses, as well as the GM dexos1 gasoline engine oil approval. ILSAC GF-6 AND GM DEXOS1 Modern gasoline direct injection (GDI) engines have achieved levels of power and fuel economy never before possible in passenger car engines. As a result, smaller engines operate at much higher loads across all engine speeds. This has caused increased wear in critical areas of the engine, and created a destructive phenomenon called low-speed pre-ignition (LSPI). The unique, state-of-the-art additive technology in Royal Purple High Performance engine oils is designed specifically to address these issues, and help engines maintain performance and reliability.

Product Features:

Better Wear Protection
Increased Protection against Low Speed Pre-Ignition
Increased Fuel Efficiency
Better Protection for Vehicle Exhaust Emissions Equipment
Improved Compatibility with Fuels Containing Ethanol
Superior Corrosion Protection
Made in USA

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$15.99

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Crowned raceways and rollers to ensure even load distribution for maximum life
Industry leading coverage
Professional technicians know they can depend on National

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$26.49

National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:

Premium bearing design matches OEM specifications
Precision manufactured using premium-grade steel for outstanding durability and performance
Crowned raceways and rollers to ensure even load distribution for maximum life
Industry leading coverage
Professional technicians know they can depend on National

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$19.24

Pinion Seal

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$11.48

Pinion Seal

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$61.97

4WD Actuator Valve

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$74.67

4WD Actuator Valve

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$41.99

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$23.99

Spindle nut for Dana 50 & 60, with pin, 2″ I.D. This replaces Spicer part number 660568.

Product Features:

Spindle nut for Dana Spicer 50 and 60
2.00″ I.D.
With pin

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$454.99

Yukon Master Overhaul kits give you all the high quality parts you need to start & finish every differential job. Yukon offers more tailor-made kits than any other manufacturer in the industry to meet your specific installation needs. This kit uses Timken bearings and races along with high quality seals and small parts. Included in this kit are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), Thread locking compound, marking compound with brush, and gasket. Yukon’s Master Overhaul kits are the most comprehensive and complete kits on the market. They do extensive research to ensure that every kit is specially tailored to your application.

Product Features:

Fits Dana Spicer 60 front
Included are Timken bearings and races, pinion bearings and races, pinion seal, axle seals, complete shim kit, ring gear bolts, pinion nut, crush sleeve , oil baffles and slingers , thread locker, marking compound with brush, and gasket.

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$122.99

Motive Gear Differential Bearing Kits Include Front & Rear Pinion Bearing, Pinion Seal, Carrier Bearings, Pilot Bearing Where Applicable, Gear Marking Compound, Crush Sleeve, Pinion Nut, Brush, Thread Locking Compound And Cover Gasket Or Rtv

Product Features:

DANA 50 BRG KIT ’98-ON 3/4 AND EXCURSION

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$44.99

Yukon 1310 U/Joint with zerk fitting on cross. 3.219″ snap ring span, 1.062″ cap diameter. Outside snap ring.

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$19.99

Backed by superior materials and rigorous testing, MOOG Heavy Duty universal joints deliver reliable performance you can count on. MOOG problem-solving innovations ensure fast, hassle-free installation.

Product Features:

BUILT TO LAST — Rugged design specifically engineered for fleets, off-highway and commercial vehicles
STRONG AND DURABLE — Bearing cups are cold-formed, case-hardened and precision ground for strength and durability
KEEPS DIRT OUT — Abrasion-resistant nitrile seals provide ideal grease retention and protection from under-vehicle contaminants
GREASEABLE DESIGN — Drilled and tapped grease fitting holes for easy servicing and cross trunnions with large grease reservoirs with radial grease channels for grease distribution
INHIBITS PREMATURE WEAR — Cross trunnions ground to a 15-25 RMS finish for a smooth surface free of microscopic grooves that can cause premature wear
RELIABLE PERFORMANCE — Internal anti-drainback valve integrated into thrust washer controls lubrication flow and prevents dry startup
RIGOROUS TESTING — Comprehensive testing throughout design and development processes by MOOG engineers for quality you can count on

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$599.99

Yukon Ring & Pinion sets give you the confidence of knowing you’re running gears designed for the harshest of conditions. Whether it’s on the street, off-road, or at the track; Yukon ring & pinion sets deliver unrivaled performance & quality. Yukon uses the latest designs and manufacturing technologies to provide a quiet running gear that is strong and easy to set up. All Yukon ring & pinion sets come standard with a one-year warranty.

Product Features:

Fits reverse rotation Dana Spicer 60
9.75″ ring gear diameter
29 spline pinion
12 ring gear bolts
3.73 ratio

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$419.99

Fits Dana Spicer 50
9.00″ ring gear diameter
26 spline pinion
10 ring gear bolts
3.73 ratio

Upgrade your 2021 Ford F-250 Super Duty with Top-Quality Drivetrains

When it comes to maintaining or upgrading your 2021 Ford F-250 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Drivetrains are key to keeping your F-250 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 49 Drivetrains for the 2021 Ford F-250 Super Duty, designed to meet your needs without breaking the bank. From Universal Joint replacements to Differentials upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Drivetrains for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Drivetrains for your 2021 Ford F-250 Super Duty at great prices. Our Drivetrains inventory for this model ranges from just $12.49 to $789.99, with an average price of $148.81. Our 49 Drivetrains in stock come from 14 trusted brands, so you’re sure to find the right part for your 2021 Ford F-250 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 Ford F-250 Super Duty, we stock popular OEM and aftermarket Drivetrains from top names like Valvoline, Royal Purple, Spicer, and more. Valvoline Drivetrains start at just $12.49 and boast an impressive 5 stars average rating from customers. Royal Purple and Spicer also bring quality to the table, with Drivetrains available starting at $12.99, and at an average 5 stars rating. With 6,530 customer reviews and counting, our 2021 Ford F-250 Super Duty Drivetrains have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Drivetrain upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Ford F-250 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your F-250 Super Duty in top shape, all in one place. Start shopping confidently below for your 2021 Ford F-250 Super Duty!

Best-Selling Universal Joints for 2021 Ford F-250 Super Duties

Enhance the driving experience in your Ford with 4 quality Universal Joint components, starting at $41.99.

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$41.99

When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles in a wide variety of applications, from light vehicle to commercial and off-highway.

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$68.99

You expect a lot from your vehicle, and Spicer Life Series (SPL) universal joints deliver. SPL universal joints consistently outperform competitors, so you can hit the road or trail with confidence. Check out the difference that SPL universal joints can make in your vehicle, and make sure you’re getting the longer life, increased bearing capacity and lower maintenance costs that Spicer Life Series (SPL) can provide.

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$149.99

SPICER U-JOINT

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$90.99

Universal Joint

Most Popular 2021 Ford F-250 Super Duty Differentials

Customize your Ford with 26 Differentials products like Differential Oil, Differential Covers, and Differential Bearings, all priced under $789.99.

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$14.49

Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, and Allison C-4.

Product Features:

Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
Enhanced anti-shudder protection for smooth shifting and maximum power transfer
Developed with anti-wear technology to help improve transmission durability
Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures

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$12.99

Better Wear Protection
Increased Protection against Low Speed Pre-Ignition
Increased Fuel Efficiency
Better Protection for Vehicle Exhaust Emissions Equipment
Improved Compatibility with Fuels Containing Ethanol
Superior Corrosion Protection
Made in USA

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$19.49

Max ATF is a synthetic, high-performance, automatic transmission fluid. Its low co-efficient of friction and high film strength help to dramatically reduce heat and wear. Additionally, Max ATF is more oxidation stable than other transmission fluids for longer fluid life. Max ATF significantly reduces heat to extend the life of your transmission.

Product Features:

High performance automatic transmission fluid
High film strength helps to dramatically reduce heat and wear
Fully compatible and can be mixed with other automatic transmission fluids
Extends the life of your transmission

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$25.99

Max Gear is recommended for truck and automotive differentials, outboard motor lower units or in rear axles or manual transmissions requiring an API fluid. Max Gear is a high performance automotive gear oil designed to provide maximum protection to heavily loaded gears while increasing power throughput through the drive train. Max Gear virtually eliminates both gear and bearing wear-even under severe squeeze film conditions caused by extremely high loads, sudden shock loads or low RPMs. Slippery, synthetic molecules not only reduce wear and friction but significantly increase Max Gear’s cold weather fluidity and lubricity, making it the ideal choice for vehicles operating in cold climates. Gears run smoother, quieter, cooler and longer without overhauls. It is noncorrosive to both ferrous and nonferrous metals.

Product Features:

Maximizes horsepower
Extends gear and bearing life
Reduces operating temperature
Lower coefficient of friction
Superior corrosion protection
Separates rapidly from water
For use with open, limited-slip and locking differential
Contains limited-slip friction modifier
Made in USA

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$69.99

Valvoline SAE 75W-140 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our formulation provides exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity and wear resistance, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. It’s recommended for conventional rear axles and transmissions requiring EP gear lubes under high speed, high load, high torque and high horsepower conditions.

Product Features:

EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -22F to 390F degrees
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5

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$16.99

Value-priced bearing meets all cataloged application requirements.

Product Features:

Brand may vary by location

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$13.79

Value-priced bearing meets all cataloged application requirements.

Product Features:

Brand may vary by location

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$19.99

We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-140 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-140 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:

FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations
EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5

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$12.99

Royal Purple HMX SAE 5W-30 High-Mileage Synthetic Motor Oil, 1 quart is specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles. Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology Synerlec, HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines. In addition, HMX is fortified with stout detergents to remove engine build-up and deposits, maintain cleanliness and promote engine longevity.

Product Features:

Specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles
Formulated with robust zinc/phosphorus anti-wear compounds combined with royal purple’s proprietary additive technology
Hmx is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines
Reduces friction and metal-to-metal contact for peak engine performance
Also provides outstanding oxidation resistance to safely extend oil drain intervals, and an ionic attraction to metal surfaces, providing protection and minimizing wear at start-up
High-Mileage Formula: Specifically designed for engines with more than 75,000 miles, this full synthetic engine oil helps minimize wear and restore lost performance.

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$434.99

AxleAssy Front Right

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$432.99

AxleAssy Front Left

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$789.99

Fits 2011 and up Ford 10.5″ housing with OEM ring and pinion set
Included are Timken bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve, thread locker, marking compound with brush, and gasket.

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$559.99

Axle Shaft

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$45.90

Timken understands how important seals are in the automotive industry. Leveraging our knowledge and experience with bearings, we offer a broad line of light-duty oil seals made exclusively for Timken in some of the world’s most advanced manufacturing plants.

Product Features:

Machined rubber sealing edge provides greater accuracy and consistency, as well as a better sealing surface.
The flanged design allows for easier and proper installation and helps avoid cocking.
The latex bore coat seals the outer diameter leak path and helps compensate for minor bore imperfections.
Extra dust lip helps keep harmful contaminants, such as dirt, out of the bearing and protects against rust and corrosion.

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$60.23

SKF is a supplier of original equipment wheel bearings, hubs and seals to most of the world’s leading automakers. Engineered and manufactured to the highest quality standards, SKF wheel bearings greatly reduce friction and increase load-carrying capabilities. With an ability to boost reliability under heavy loads and misaligned conditions, SKF wheel bearings offer an ideal solution for many wheel end applications.

Product Features:

Precision bearing pre-load and correct application of advanced manufacturing techniques such as orbital rolling
100% tested to the actual OE specifications per part number for fit, form and function
High quality steel and surface finishes
Proper implementation of heat treatment

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$37.46

Dorman’s Differential Cover is engineered for long-lasting protection of the differential. Designed as a direct replacement, a proper fit is assured every time.

Product Features:

Comes with pre-installed magnet in cover
Corrosion resistant coating to help prevent rusting
Includes high quality rubber fill plug (where applicable)
Constructed from durable stamped steel

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$49.21

Differential Cover

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$18.29

Valvoline ULV is a full synthetic, ultra low viscosity transmission fluid specifically engineered for high speed automatic transmissions. Formulated to meet the performance requirements of the latest 9 & 10 speed transmission designs, including the Ford/GM 10R80 found in select Ford F-150 and Raptor trucks.

Product Features:

Formulated with premium synthetic base oils to achieve low viscosity and minimize deposits
Provides excellent thermal and oxidation performance
Durable friction modifiers help prevent shudder
Advanced anti-wear technology to better prevent gear wear

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$664.99

Product Features:

35 spline
Fits Super Dana Spicer 60 in 2010-2011 Ford F250 and F350
Right hand side

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$584.99

RngPnnKt

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$397.99

External Fins Transfer Heat To Atmosphere
Internal Fins Absorb Heat From Lubricating Fluid
Magnetic Fill Plug
Magnetic Drain Plug

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$44.48

Axle Seal

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$38.33

Diff. Carrier Bearin

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$24.85

Wheel Bearing

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$19.24

Pinion Seal

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$12.49

Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:

HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions

Top Picks for 2021 Ford F-250 Super Duty Drive Shafts and Axles

Upgrade Ford F-250 Super Duties with top-quality Drive Shafts and Axles parts, including 10 OEM and aftermarket selections for your 2021 model.

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from

$40.99

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$20.29

Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$51.99

from

$81.99

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$21.63

SKF’s advanced PTFE oil seal offers optimum performance in extreme temperature and fluid environments. Other benefits of this seal include; reduced friction, longer service life, easier assembly, reduced weight and compact design.

Product Features:

Machined rubber sealing edge provides greater accuracy and consistency, as well as a better sealing surface.
The flanged design allows for easier and proper installation and helps avoid cocking.
The latex bore coat seals the outer diameter leak path and helps compensate for minor bore imperfections.
Extra dust lip helps keep harmful contaminants, such as dirt, out of the bearing and protects against rust and corrosion.

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$744.99

Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
Serviceable construction – non-staked universal joints are designed for future serviceability

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$537.99

Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance.
100% new – this drive shaft is made from all new components so there’s no core charge or return hassle.
Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
Serviceable construction – non-staked universal joints are designed for future serviceability

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$102.99

Axle Shft Univ Joint

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$99.99

Center Support Bearing

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$55.99

Universal Joint

In-Demand 4WD Components for 2021 Ford F-250 Super Duties

Select from 4 premium 4WD Components parts for your 2021 Ford F-250 Super Duty, with prices ranging from $45.49 to $196.86.

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$45.49

This 4WD hub locking solenoid directly replaces the original equipment solenoid on certain vehicle years, makes and models.

Product Features:

Direct replacement – this 4WD hub locking solenoid matches the fit and function of the stock solenoid on certain vehicle applications.
Effective fix – restores control of 4WD system impacted by failed original solenoid.
Thoroughly tested – on-vehicle and laboratory testing ensures trouble-free operation
Trustworthy quality – backed by team of designers and engineers in the United States

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$61.97

4WD Actuator Valve

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$196.86

Locking Hub

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$74.67

4WD Actuator Valve

Most Sold 2021 Ford F-250 Super Duty Spindles

Explore our best-selling Ford parts for the 2021 F-250 Super Duty among 5 OEM and aftermarket options starting from $12.99.

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$12.99

Low swell in hydrocarbon fluids
Design type: spring loaded; multi-lip
Provides good low temperature capability
Temperature range: -40°F to 225°F; -40°C to 107°C
Delivers quality and reliable performance for every type of repair

from

$33.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$36.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

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$36.49

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

from

$41.99

This spindle nut is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:

Direct replacement – this spindle nut matches the fit and function of the factory part on specified years, makes and models.
Ideal solution – this nut is a reliable replacement for an original part that is missing or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

Top-Rated Drivetrains Brands For Your 2021 Ford F-250 Super Duty

Shop for the best-rated brands offering Drivetrains and other products for your 2021 Ford F-250 Super Duties. Below you’ll find some of our best rated Drivetrains from Valvoline, Royal Purple, and Spicer, and more. Drivetrains from these brands that fit a 2021 F-250 Super Duty start at just $12.49 and are rated as high as 5 stars. OEM and aftermarket Drivetrains don’t get more top quality, durable, and affordable than from the brands below.

Popular Valvoline 2021 Ford F-250 Super Duty Drivetrains

When it comes to maintaining or upgrading your 2021 Ford F-250 Super Duty, using quality Drivetrains is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Drivetrains, specifically designed for the 2021 Ford F-250 Super Duty. With over 5 Valvoline brand Drivetrains in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $12.49, with an average price of just $27.05. Plus, with over 366 customer reviews and an average rating of 5 stars, you can trust that our Valvoline Drivetrains will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

from
$12.49

This product is not rated

High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart

“”

from
$18.29

This product is not rated

ULV ATF Full Synthetic Ultra Low Viscosity Automatic Transmission Fluid, 1 Quart

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from
$19.99

This product is not rated

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart

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Popular Royal Purple 2021 Ford F-250 Super Duty Drivetrains

Royal Purple auto parts is one of the highest quality Drivetrain brands in the market. Any 2021 Ford F-250 Super Duty owner should feel confident when installing genuine Royal Purple parts in their vehicle. To ensure the best fit and performance for your 2021 F-250 Super Duty, Advance Auto Parts carries a full inventory of 4 Royal Purple Drivetrains. Plus you will be keeping your Ford in peak condition while saving money because prices on these Royal Purple Drivetrains range from $12.99 to $25.99, plus, with more than 169 customer reviews and an impressive 5 stars average rating, you can be confident the Fram Drivetrains below will deliver on both quality and value.

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$19.49

(30)

Max Automatic Transmission Fluid (1 Quart)

“I would like to know can I use this for my 2012 Dodge Charger”

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$12.99

(82)

High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT

“best oil”

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$12.99

This product is not rated

HMX SAE 5W-30 High-Mileage Synthetic Engine Oil (1 Quart)

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FAQs for 2021 Ford F-250 Super Duty Drivetrains

Which Drivetrains are best-sellers for 2021 Ford F-250 Super Duties?

Out of 49 Drivetrains that fit 2021 Ford F-250 Super Duties, the following parts are the top sellers:

High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT (8070001) – $12.99
Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart (12507272) – $19.99
Max Automatic Transmission Fluid (1 Quart) (8150028) – $19.49

What’s the price range for 2021 Ford F-250 Super Duty Drivetrains?

Drivetrain prices for the 2021 Ford F-250 Super Duty start at $12.49 and go up to $789.99 for the most premium parts.

What’s the average price of a Drivetrain for a 2021 Ford F-250 Super Duty?

The average price for Drivetrains for the 2021 Ford F-250 Super Duty is $148.81. Keep in mind the variety of part types within our Drivetrain category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Drivetrains for other Ford F-250 Super Duty model years?

Yes, we currently carry Drivetrains for 25 model years of Ford F-250 Super Duties between 1999 and 2024. Drivetrains are bought most frequently for the following model years: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Drivetrains for my 2021 Ford F-250 Super Duty?

The cheapest 2021 Ford F-250 Super Duty Drivetrains we carry in stock are:

High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart (11301050) – $12.49
High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT (8070001) – $12.99
Multi Purpose Seal (11077032) – $12.99
HMX SAE 5W-30 High-Mileage Synthetic Engine Oil (1 Quart) (11946678) – $12.99
Taper Bearing Set (5050766) – $13.79

What are the top-rated Drivetrains that fit the 2021 Ford F-250 Super Duty?

Out of 6,530 reviews by customers, our 2021 Ford F-250 Super Duty Drivetrains have an average customer rating of . These are some of the highest-rated Drivetrain types for the 2021 Ford F-250 Super Duty and their top-rated products:

4WD Components
- Solenoid, 4WD Engage And Emissions Purge (10086502) – $45.49
Spindles
- Solenoid, 4WD Engage And Emissions Purge (10086502) – $45.49

What types of Drivetrains do you sell for my 2021 Ford F-250 Super Duty?

As of 2/5/25, these are some of the most in-demand types of Drivetrains for a 2021 Ford F-250 Super Duty:

Can I get help with 2021 Ford F-250 Super Duty Drivetrain orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Drivetrains and more.

What is your return policy for Ford F-250 Super Duty Drivetrains?

Advance Auto Parts keeps returns simple. For new Ford F-250 Super Duty Drivetrains and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2021 Ford F-250 Super Duty Drivetrains

Motive Gear – Differential Carrier Bearing Kit – Koyo (Part No.R10.5CK)

Carquest Premium – 4WD Actuator (Part No.FWA1014)

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Spicer – Axle Shft Univ Joint (Part No.SPL55-4X)

aFe POWER – Differential Cover (Part No.46-70022)

Dorman – Front Axle Shaft Kit with Universal Joint, 1541H (Part No.630-435)

National – Multi Purpose Seal (Part No.710493)

Spicer – Differential Seal (Part No.J7040444357SPI)

MTC – Locking Hub (Part No.K70282575794MTC)

National – Multi Purpose Seal (Part No.710413)

Dorman – Rear Drive Shaft: Greaseable, Adjustable (Part No.976-343)

SKF – Driveshaft Support (Part No.K10301069521SKF)

Valvoline – DEX/MERC Automatic Transmission Fluid, 1 Gallon (Part No.773636)

Royal Purple – High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT (Part No.01530)

National – Bearings (Part No.LM104911A)

National – Bearings (Part No.28521)

SKF – Pinion Seal (Part No.J7010481300SKF)

SKF – Pinion Seal (Part No.J7010247045SKF)

Dorman – 4WD Actuator Valve (Part No.J7603829822DOR)

Motorcraft – 4WD Actuator Valve (Part No.J7603674059MTR)

Dorman – Spindle Nut 2 In.-16L Hex Size 3 In. (sold by each) (Part No.615-134)

Yukon Gear – Spindle Nut For Dana 50 & 60, With Pin, 2" I.D. (Part No.33496)

Yukon Gear – Master Overhaul Kit For Dana 60 And 61 Front Differential (Part No.14128)

Motive Gear – Differential Bearing Kit – Koyo (Part No.R50RL)

Yukon Gear – 1310 U/Joint With Zerk Fitting On Cross (Part No.42008)

MOOG Driveline Products – Greaseable Premium Universal Joint (Part No.331)

Yukon Gear – High Performance Ring & Pinion Gear Set For Dana 60 Reverse Rotation In A 3.73 Ratio (Part No.24310)

Yukon Gear – High Performance Ring & Pinion Gear Set For Dana 50 Reverse Rotation In A 3.73 Ratio (Part No.24298)

Spicer – Universal Joint (Part No.5-188X)

Spicer – Universal Joint (Part No.SPL55X)

Spicer – SPICER U-JOINT (Part No.SPL70-4X)

Spicer – Universal Joint (Part No.SPL55-1X)

Valvoline – DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.822405)

Royal Purple – High Performance SAE 5W30 Synthetic Motor Oil, API Certified, 1 QT (Part No.01530)

Royal Purple – Max Automatic Transmission Fluid (1 Quart) (Part No.01320)

Royal Purple – MaxGear SAE 75W140 High Performance Gear Oil w/Friction Modifier Additive, 1 QT (Part No.01301)

Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon (Part No.887344)

Driveworks – Tapered Cone Wheel Bearing Assembly (Part No.S-387-AS)

Driveworks – Taper Bearing Set (Part No.S-A-38)

Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Quart (Part No.889787)

Royal Purple – HMX SAE 5W-30 High-Mileage Synthetic Engine Oil (1 Quart) (Part No.11744)

USA Standard Gear – AxleAssy Front Right (Part No.35213)

USA Standard Gear – AxleAssy Front Left (Part No.35214)

Yukon Gear – Master Overhaul Kit For 2011 & Up Ford 10.5" Differentials Using OEM Ring & Pinion (Part No.14201)

Yukon Gear – Axle Shaft (Part No.21754)

Timken – Axle Shaft Seal (Part No.K4021473864TIM)

SKF – Wheel Bearing (Part No.K8000205983SKF)

Dorman – Rear Differential Cover (Part No.J7019701310DOR)

Spicer – Differential Cover (Part No.J7019764553SPI)

Valvoline – ULV ATF Full Synthetic Ultra Low Viscosity Automatic Transmission Fluid, 1 Quart (Part No.888460)

Yukon Gear – Right Hand Axle Assembly For ’05-’12 Ford "Super 60" F250/F350 Front, With Stub Axle Seal (Part No.21753)

Yukon Gear – RngPnnKt (Part No.24709)

aFe POWER – Differential Cover (Part No.46-70022)

Autopart International Inc – Axle Seal (Part No.K40212042027API)

SKF – Diff. Carrier Bearin (Part No.J7016820463SKF)

Autopart International Inc – Wheel Bearing (Part No.K80001953102API)

SKF – Pinion Seal (Part No.J7010481300SKF)

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart (Part No.VV820)

Spicer – Universal Joint (Part No.5-160X)

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Spicer – Universal Joint (Part No.5-1410X)

Spicer – Universal Joint (Part No.SPL55-3X)

SKF – Axle Shaft Seal (Part No.K4021427598SKF)

Dorman – Front Drive Shaft: Greaseable (Part No.938-293)

Dorman – Rear Drive Shaft: Adjustable (Part No.976-296)

Spicer – Axle Shft Univ Joint (Part No.SPL55-4X)

Spicer – Center Support Bearing (Part No.5023815)

Spicer – Universal Joint (Part No.5-1410-1X)

Dorman – Solenoid, 4WD Engage And Emissions Purge (Part No.600-400)

Dorman – 4WD Actuator Valve (Part No.J7603829822DOR)

MTC – Locking Hub (Part No.K7028814093MTC)

Motorcraft – 4WD Actuator Valve (Part No.J7603674059MTR)

National – Multi Purpose Seal (Part No.710701)

Dorman – Spindle Nut 2 In.-16 L Hex Size 3 In. (Part No.615-134.1)

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (sold by each) (Part No.615-133)

Dorman – Spindle Nut 2 In.-16 Hex Size 3 In. (Part No.615-133.1)

Dorman – Spindle Nut 2 In.-16L Hex Size 3 In. (sold by each) (Part No.615-134)