2021 Ford E-450 Super Duty Engine Cooling Parts

Essential 2021 Ford E-450 Super Duty Engine Cooling Parts

Felpro – Multi-Purpose O-Ring (Part No.35489)

Multi-Purpose O-Ring

from

$9.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Mahle – Water Pipe O-Ring (Part No.G2026948678MAH)

Water Pipe O-Ring

from

$1.41
Water Pipe O-Ring

Motorcraft – Thermostat O-Ring (Part No.G4030195862MTR)

Thermostat O-Ring

from

$3.89
Thermostat O-Ring

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10238)

Engine Coolant Reservoir Cap

from

$9.79
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Motorcraft – Original Equipment Radiator Cap (Part No.G1010415176MTR)

Original Equipment Radiator Cap

from

$10.79
The Motorcraft Original Equipment Radiator Cap is an OES replacement component that provides the same performance, durability, and service life as your factory original equipment.

Product Features:
  • Standard and safety vent radiator pressure caps available
  • Extensive coverage for most cars and trucks, as well as farm and construction equipment
  • Swivel-seal radiator caps are designed to provide increased durability and can be removed without damage to the rubber atmospheric seal
  • Zinc-plated to resist corrosion and rust
  • Pressure valve springs are made of stainless steel to maintain calibrated pressure throughout the service life
  • Rubber pressure valve gasket resists high temperatures and deterioration from coolant and additives
  • Pressure and vacuum relief features help extend radiator and hose life
  • Prevent accidental cap removal with positive low-pressure stop feature
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Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54208)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$14.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
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Motorcraft – Motorcraft Thermostat (Part No.G4000349158MTR)

Motorcraft Thermostat

from

$19.78
The Motorcraft Thermostat is a direct fit OEM replacement that guarantees the same performance and quality provided by the vehicle manufacturer.

Product Features:
  • Heavy-duty quality for long life
  • Stainless steel or brass bridge and spring frame, channel-constructed for strength and rigidity
  • Stainless steel, tapered-end pistons with flexible elastomeric boots
  • Streamlined venturi nozzle for maximum coolant flow
  • Brass cover and guide for heat motor piston
  • Mounting flange designed to properly fit and seat the thermostat in the housing
  • Stainless steel spring offers precise operating compression
  • Heat motor in high-strength brass housing
  • Rulon seal for heat motor piston
  • Specially formulated expansive wax compound
See More

Motorcraft – Motorcraft Thermostat (Part No.G4000319009MTR)

Motorcraft Thermostat

from

$55.28
The Motorcraft Thermostat is a direct fit OEM replacement that guarantees the same performance and quality provided by the vehicle manufacturer.

Product Features:
  • Heavy-duty quality for long life
  • Stainless steel or brass bridge and spring frame, channel-constructed for strength and rigidity
  • Stainless steel, tapered-end pistons with flexible elastomeric boots
  • Streamlined venturi nozzle for maximum coolant flow
  • Brass cover and guide for heat motor piston
  • Mounting flange designed to properly fit and seat the thermostat in the housing
  • Stainless steel spring offers precise operating compression
  • Heat motor in high-strength brass housing
  • Rulon seal for heat motor piston
  • Specially formulated expansive wax compound
See More

Carquest Premium – Standard Thermostat: 192 Degrees (Part No.14269)

Standard Thermostat: 192 Degrees

from

$17.29
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 195 Degrees (Part No.14989)

Standard Thermostat: 195 Degrees

from

$15.79
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13778)

Standard Thermostat: 180 Degrees

from

$15.79
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – High Flow Thermostat: 180 Degrees (Part No.13968)

High Flow Thermostat: 180 Degrees

from

$12.49
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

Motorcraft – Thermostat (Part No.G4000212055MTR)

Thermostat

from

$47.78
The Motorcraft Thermostat is a direct fit OEM replacement that guarantees the same performance and quality provided by the vehicle manufacturer.

Product Features:
  • Heavy-duty quality for long life
  • Stainless steel or brass bridge and spring frame, channel-constructed for strength and rigidity
  • Stainless steel, tapered-end pistons with flexible elastomeric boots
  • Streamlined venturi nozzle for maximum coolant flow
  • Brass cover and guide for heat motor piston
  • Mounting flange designed to properly fit and seat the thermostat in the housing
  • Stainless steel spring offers precise operating compression
  • Heat motor in high-strength brass housing
  • Rulon seal for heat motor piston
  • Specially formulated expansive wax compound
See More

Motorad UltraStats – Thermostat: 195 Degrees (Part No.5228-195JV)

Thermostat: 195 Degrees

from

$18.29
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

Motorad UltraStats – Thermostat: 180 Degrees (Part No.5228-180JV)

Thermostat: 180 Degrees

from

$18.29
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

Motorcraft – ENG COOLANT THRMSTAT (Part No.RT-1201)

ENG COOLANT THRMSTAT

from

$57.99
ENG COOLANT THRMSTAT

Carquest Premium – Standard Thermostat: With Seal, 192 Degrees (Part No.1121-192)

Standard Thermostat: With Seal, 192 Degrees

from

$60.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorcraft – ENG COOLANT THRMSTAT (Part No.RT-1195)

ENG COOLANT THRMSTAT

from

$20.99
ENG COOLANT THRMSTAT

Motorcraft – ORIGINAL EQUIPMENT THERMOSTAT (Part No.RT-1169)

ORIGINAL EQUIPMENT THERMOSTAT

from

$45.99
ORIGINAL EQUIPMENT THERMOSTAT

Carquest Premium – Standard Thermostat: 195 Degrees (Part No.13779)

Standard Thermostat: 195 Degrees

from

$15.79
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad UltraStats – Thermostat: 192 Degrees (Part No.5378-192)

Thermostat: 192 Degrees

from

$35.99
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
See More

Carquest Premium Stats – High Flow Thermostat: 180 Degrees (Part No.45778)

High Flow Thermostat: 180 Degrees

from

$15.79
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – High Flow Thermostat: 170 Degrees (Part No.13967)

High Flow Thermostat: 170 Degrees

from

$14.29
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. With the enlarged Orpheus opening, this high flowing thermostat will allow for more gallons per second to flow. This will allow for the engine to cool down at a faster rate compared to the OE to allow for quick and precise cooling for your engine. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • Larger opening for increased coolant flow
  • Increased strength and durability
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • 100% tested and calibrated
See More

2021 Ford E-450 Super Duty Engine Cooling Parts

Maybe you’re in the middle of a full rebuild of that 2021 Ford E-450 Super Duty. Maybe you just need a couple of Engine Cooling Parts. Either way, Advance Auto Parts has 5 different Engine Cooling Parts in our inventory ranging from $3.89 to $60.99. That means you can find the exact parts or products you need to keep that 2021 Ford E-450 Super Duty running smoothly.

Engine Cooling Parts are only as good as their brand. We stock 3 different brands to make sure you have plenty of trusted parts to choose from for your 2021 Ford E-450 Super Duty. Felpro, Carquest Premium, and Motorcraft are just some of the brands we stock. Search for brands you know or compare prices and reviews to help you decide!

We know you’ll find the perfect Engine Cooling Parts for your 2021 Ford E-450 Super Duty, but don’t take our word for it – read our customer ratings and reviews and buy with confidence.

So if you’re in the market for aftermarket Engine Cooling Parts to keep your 2021 Ford E-450 Super Duty rolling for years to come, look no further. Shop online and have your products shipped direct to your door, or pick up at the nearest Advance Auto Parts location today!

Engine Cooling Parts Brands To Make Your 2021 Ford E-450 Super Duty Last

Simple repair, complete replacement, or a full rebuild. No matter the job, your 2021 Ford E-450 Super Duty demands trusted brand parts and products to keep it running. Many trusted brands of Engine Cooling Parts make up Advance Auto Parts’ inventory, and all are ready to help make your E-450 Super Duty the best it can be. Be sure to browse some of our top Engine Cooling Parts brands and parts.

Popular Felpro Engine Cooling Parts

We carry Felpro parts in our stock across Engine Coolant Pipe O-Rings categories, plus more. For a 2021 Ford E-450 Super Duty, our most popular Felpro Engine Cooling Parts include:
Multi-Purpose O-Ring
from $9.99
(110)
Multi-Purpose O-Ring
Engine Coolant Pipe O-Rings

FAQs for 2021 Ford E-450 Super Duty Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the 2021 Ford E-450 Super Duty?

Out of 5 Engine Cooling Parts for the 2021 Ford E-450 Super Duty, the most popular in our inventory are:
Engine Coolant Reservoir Cap
from $9.79
(26)
Engine Coolant Reservoir Cap
Coolant Reservoir Caps
Standard Thermostat: With Seal, 192 Degrees
from $60.99
This product is not rated
Standard Thermostat: With Seal, 192 Degrees
Thermostats
Thermostat O-Ring
from $3.89
This product is not rated
Thermostat O-Ring
Thermostat Housing Gaskets