2021 Ford E-350 Super Duty Spark Plugs

Your 2021 Ford E-350 Super Duty might be the best vehicle you’ve ever owned. Or you may just be struggling to keep it highway-approved. No matter the situation, Advance Auto Parts has the Spark Plugs you desperately need.

We currently carry 6 Spark Plugs to choose from for your 2021 Ford E-350 Super Duty, and our inventory prices range from as little as $7.99 up to $14.79.

On top of low prices, Advance Auto Parts offers 4 different trusted brands of Spark Plugs for the 2021 Ford E-350 Super Duty. We only sell parts from trusted brands like E3 so that you can find quality parts you can count on.

Don’t take our word for it – check out customer ratings and reviews to buy with confidence. We have 354 reviews on our Spark Plugs for the 2021 Ford E-350 Super Duty from previous customers.

Have parts delivered straight to your home, or find the nearest Advance Auto Parts store to check out our Spark Plugs stock in-person!

Spark Plugs for Your 2021 Ford E-350 Super Duty

NGK – Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX (Part No.95605)

Ruthenium HX High Ignitability Spark Plug: PSPE Tip Design, LTR7BHX

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$14.79
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug; Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY PROJECTED SQUARE PLATINUM ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with a unique cut-back PSPE ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PSPE DESIGN: Projected square platinum electrode shape of the ground electrode provides the best ignitability and service life for high heat engines
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE PSPE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Enhanced Fuel Burn: Provides a more complete fuel burn, resulting in quicker throttle response, smoother idle, and better cold starts.
  • Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.
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E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

DiamondFIRE Automotive Spark Plug: More Power, Saves Gas

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$8.49
The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:
  • E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
  • Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
  • Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
  • Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
  • E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
  • The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
  • Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
  • Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
  • Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
  • Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.
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NGK – OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13 (Part No.94862)

OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13

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$13.99
NGK Laser Platinum spark plugs provide high ignitability and longer service life compared to conventional nickel spark plugs. Laser Platinum plugs are tested to the highest standards to ensure quality and durability. Engineered specifically for OE applications. Laser platinum plugs provide stable idling, superior anti-fouling, improved fuel efficiency and lower emissions. High-grade pure alumina ceramic and 98% pure copper core prevents spark plug from overheating and provides reliable starts. Most Laser Platinum spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:
  • ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire platinum alloy center electrode provides consistent performance
  • PLATINUM ALLOY CENTER ELECTRODE: Longer wearing and higher temperature resistance compared to traditional nickel spark plugs
  • PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Best for vehicles with OE fine wire platinum alloy plugs
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Motorcraft – Spark Plug (Part No.F10003269731MTR)

Spark Plug

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$9.18
Spark Plug

Autolite Iridium – Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition (Part No.XP5862)

Iridium XP Finewire Spark Plug: Improved Durability, More Focused Ignition

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$8.99
Our best spark plug! Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.

Product Features:
  • 0.6 mm finewire design improves ignitability
  • Patented V-trimmed platinum sidewire technology resists wear
  • OE equivalent design is engineered for every engine
  • Designed for better overall durability with virtually no gap erosion
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Motorcraft – High-Performance Spark Plug: Enhances Fuel Efficiency (Part No.SP-589)

High-Performance Spark Plug: Enhances Fuel Efficiency

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$7.99
Engineered for superior ignition performance, the Motorcraft High-Performance Spark Plug is designed to optimize fuel efficiency and ensure reliable starts. Crafted with precision, this spark plug offers exceptional durability and consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance. Upgrade to Motorcraft and experience the difference in your engine’s responsiveness and fuel economy.

Product Features:
  • Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
  • Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
  • Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
  • Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
  • Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
  • Enhances Fuel Efficiency: The Motorcraft High-Performance Spark Plug is specifically designed to optimize fuel efficiency, helping you save on fuel costs.
  • Superior Ignition Performance: Engineered for superior ignition performance, this spark plug ensures reliable starts every time.
  • Exceptional Durability: Crafted with precision, the Motorcraft High-Performance Spark Plug offers exceptional durability, providing long-lasting performance.
  • Consistent Performance: This spark plug delivers consistent performance, making it an ideal choice for maintaining your vehicle’s peak performance.
  • Improved Engine Responsiveness: Upgrade to Motorcraft and experience a noticeable difference in your engine’s responsiveness and overall fuel economy.
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FAQs for 2021 Ford E-350 Super Duty Spark Plugs

What are the most popular Spark Plugs for the 2021 Ford E-350 Super Duty?

With 4 brands you can trust, our most popular Spark Plugs for the 2021 Ford E-350 Super Duty parts are:
OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13
from $13.99
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OE Series Laser Platinum Spark Plug: Fine Wire Tip Design, LTR7CP13
Spark Plugs