2008 Lexus RX350 Transmission Seals

Keep Your 2008 Lexus RX350 in Top Shape with Quality Transmission Seals

Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2008 Lexus RX350 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Manual Transmission Output Shaft Seals, Automatic Transmission Output Shaft Seals, and Extension Housing Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Competitive Prices and Extensive Inventory

The average price for a 2008 Lexus RX350 Transmission Seal at Advance Auto Parts is around $10.03, with a range that starts at $3.49 and goes up to $15.99. With 11 options in stock from 2 trusted brands, finding the right fit is easy. Popular picks like Multi-Purpose Seal, Multi Purpose Seal, and Manual Transmission Output Shaft Seal start at just $8.49 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Transmission Seal, don’t forget to check out other key components like Torque Converter and Related Products and Transmission Bearings. At Advance Auto Parts, we’re here to help you keep your 2008 Lexus RX350 in peak condition, inside and out.

Essential 2008 Lexus RX350 Transmission Seals

National – Multi-Purpose Seal (Part No.710319)

Multi-Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710319)

Manual Transmission Output Shaft Seal

from

$3.49
Product Features:
  • Brand may vary by location
See More

National – Multi-Purpose Seal (Part No.710419)

Multi-Purpose Seal

from

$8.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710112)

Manual Transmission Output Shaft Seal

from

$8.49
Product Features:
  • Brand may vary by location
See More

National – Multi-Purpose Seal (Part No.712551)

Multi-Purpose Seal

from

$15.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi-Purpose Seal (Part No.710112)

Multi-Purpose Seal

from

$14.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

National – Automatic Transmission Output Shaft Seal (Part No.711111)

Automatic Transmission Output Shaft Seal

from

$11.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Output Shaft Seal (Part No.710876)

Automatic Transmission Output Shaft Seal

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Output Shaft Seal (Part No.710732)

Automatic Transmission Output Shaft Seal

from

$16.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: – 0 Deg. F to 450 Deg. F / – 3 Deg. C to 232 Deg. C
  • Excellent dry running capabilities
  • Low coefficient of friction
  • Delivers quality and reliable performance for every type of repair
See More

FAG US – Shaft Seal (Part No.SS4892)

Shaft Seal

from

$10.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

Product Features:
  • High-precision and High-quality components used in all KITs
  • Coverage of classic and new high-tech solutions for the best system coverage
See More

National – Automatic Transmission Side Cover Seal (Part No.711095)

Automatic Transmission Side Cover Seal

from

$9.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Output Shaft Seal (Part No.710955)

Automatic Transmission Output Shaft Seal

from

$12.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.221207)

Multi Purpose Seal

from

$10.99
Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Most Popular Manual Transmission Output Shaft Seals for 2008 Lexus RX350s

Enhance your 2008 Lexus RX350 with one of the 3 Manual Transmission Output Shaft Seals we have in stock, starting at just $3.49.

National – Multi-Purpose Seal (Part No.710419)

Multi-Purpose Seal

from

$8.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; single-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710112)

Manual Transmission Output Shaft Seal

from

$8.49
Product Features:
  • Brand may vary by location
See More

Driveworks – Manual Transmission Output Shaft Seal (Part No.S-710319)

Manual Transmission Output Shaft Seal

from

$3.49
Product Features:
  • Brand may vary by location
See More

Best-Selling 2008 Lexus RX350 Automatic Transmission Output Shaft Seals

Upgrade your RX350 with one of our 3 best-selling Automatic Transmission Output Shaft Seals.

National – Automatic Transmission Output Shaft Seal (Part No.710876)

Automatic Transmission Output Shaft Seal

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Output Shaft Seal (Part No.710955)

Automatic Transmission Output Shaft Seal

from

$12.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Automatic Transmission Side Cover Seal (Part No.711095)

Automatic Transmission Side Cover Seal

from

$9.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Top-Quality Extension Housing Seals for 2008 Lexus RX350s

Choose a high-quality OEM or aftermarket Extension Housing Seal for Lexus RX350s and enjoy top-notch performance from $9.99.

National – Multi-Purpose Seal (Part No.710319)

Multi-Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

Our Top Pick for a 2008 Lexus RX350 Shaft Seal

Invest in a durable Shaft Seal for your 2008 Lexus, knowing you’re getting trusted brands and expert craftsmanship.

Driveworks – Auto Transmission Manual Shaft Seal (Part No.S-221207)

Auto Transmission Manual Shaft Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

Top-Rated Transmission Seals and O-rings for 2008 Lexus RX350s

Make a smart move for your 2008 Lexus RX350 with products all priced from $14.99 to $15.99.

National – Multi-Purpose Seal (Part No.712551)

Multi-Purpose Seal

from

$15.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -40 Deg. F to 225 Deg. F / -40 Deg. C to 107 Deg. C
  • Good low temperature capability
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi-Purpose Seal (Part No.710112)

Multi-Purpose Seal

from

$14.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -20 Deg. F to 300 Deg. F / -29 Deg. C to 49 Deg. C
  • Resistance to EP lubricants
  • Low swell in hydrocarbon fluids
  • Delivers quality and reliable performance for every type of repair
See More

FAQs for 2008 Lexus RX350 Transmission Seals

What are the best-selling Transmission Seals for 2008 Lexus RX350s?

Out of 11 Transmission Seals that fit 2008 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2008 Lexus RX350 Transmission Seals?

The prices of Transmission Seals for the 2008 Lexus RX350 range from $3.49 up to $15.99 for the most premium parts.

What is the average price of a Transmission Seal for a 2008 Lexus RX350?

The average price for Transmission Seals for the 2008 Lexus RX350 is $10.03. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Seals for other Lexus RX350 model years?

Yes, we carry Transmission Seals for 11 model years of Lexus RX350s between 2007 and 2019. The following model years are the most popular for Transmission Seal purchases: 2019, 2018, 2017, 2016, 2015, 2014, 2013, 2012, and 2011.

What are the cheapest Transmission Seals for my 2008 Lexus RX350?

The cheapest 2008 Lexus RX350 Transmission Seals we carry are:

Does Advance Auto Parts sell Transmission Seals for any other 2008 Lexus models?

Yes. We stock Transmission Seals for 10 other popular 2008 Lexus models. Some of the most popular are 2008 ES350 Transmission Seals, 2008 SC430 Transmission Seals, 2008 RX400H Transmission Seals, 2008 IS250 Transmission Seals, and 2008 IS350 Transmission Seals.

What are the top-rated Transmission Seals that fit the 2008 Lexus RX350?

The one 2008 Lexus RX350 Transmission Seal we have in stock is the Manual Transmission Output Shaft Seal. It costs $3.49.

What types of Transmission Seals do you sell for my 2008 Lexus RX350?

As of 11/2/25, these are some of the most in-demand types of Transmission Seals for a 2008 Lexus RX350:

Can I get help with 2008 Lexus RX350 Transmission Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.

What is your return policy for Lexus RX350 Transmission Seals?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.