2008 Lexus RX350 Transmission Seals

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Keep Your 2008 Lexus RX350 in Top Shape with Quality Transmission Seals

Whether you’re repairing or upgrading your Transmission Seal, using high-quality parts is key to keeping your 2008 Lexus RX350 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Manual Transmission Output Shaft Seals, Automatic Transmission Output Shaft Seals, and Extension Housing Seals. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Transmission Seals from Trusted Brands

Looking for a reliable Transmission Seal? We’ve got you covered with options from brands you know and trust like National. For example, National Transmission Seals start at just $17.29 with an average 4.3 star rating. With over 12 reviews and a solid 3.4 star average, you can shop with confidence knowing other Lexus RX350 owners approve.

Explore Related Parts

While you’re upgrading or replacing your Transmission Seal, don’t forget to check out other key components like Torque Converter and Related Products and Transmission Bearings. At Advance Auto Parts, we’re here to help you keep your 2008 Lexus RX350 in peak condition, inside and out.

Find Your Specific 2008 Lexus RX350 Transmission Seals

Looking for the perfect Transmission Seal for your 2008 Lexus RX350? You’re in the right place. Below, you’ll find links to various types of Transmission Seals that fit your vehicle. At Advance Auto Parts, we offer only the highest quality OEM and aftermarket Transmission Seals, ensuring durability and a precise fit for your Lexus RX350. Whether you’re driving a 2008 model or another popular model year like 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2021, and 2022, we’ve got you covered. Purchasing Transmission Seals from Advance Auto Parts is a smart choice, giving you access to trusted brands and parts built to perform. Below, you’ll find links to various types of Transmission Seals that fit your vehicle.

Essential 2008 Lexus RX350 Transmission Seals

National – National Multi-Purpose Seal, 2025 (Part No.2025)

National Multi-Purpose Seal, 2025

from

$17.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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(1 reviews)
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National – National Multi-Purpose Seal, 712551 (Part No.712551)

National Multi-Purpose Seal, 712551

from

$11.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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(6 reviews)
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National – National Multi-Purpose Seal, 221207 (Part No.221207)

National Multi-Purpose Seal, 221207

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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ATP – ATP Automatic Transmission Seal Drive Axle, RO-79 (Part No.RO-79)

ATP Automatic Transmission Seal Drive Axle, RO-79

from

$15.49
ATP Transmission Seals and Gaskets are exact fit, no compromise replacement parts.
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Schaeffler – Schaeffler Shaft Seal, SS2111 (Part No.SS2111)

Schaeffler Shaft Seal, SS2111

from

$5.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.
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National – National Multi-Purpose Seal, 710319 (Part No.710319)

National Multi-Purpose Seal, 710319

from

$10.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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Schaeffler – Schaeffler Shaft Seal, SS2416 (Part No.SS2416)

Schaeffler Shaft Seal, SS2416

from

$11.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.
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National – National Automatic Transmission Output Shaft Seal, 710732 (Part No.710732)

National Automatic Transmission Output Shaft Seal, 710732

from

$19.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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(2 reviews)
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Schaeffler – Schaeffler Shaft Seal, SS4892 (Part No.SS4892)

Schaeffler Shaft Seal, SS4892

from

$7.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.
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National – National Differential Pinion Seal, 710594 (Part No.710594)

National Differential Pinion Seal, 710594

from

$17.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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National – National Automatic Transmission Side Cover Seal, 711095 (Part No.711095)

National Automatic Transmission Side Cover Seal, 711095

from

$9.89
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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Driveworks – Driveworks Auto Transmission Manual Shaft Seal, S-221207 (Part No.S-221207)

Driveworks Auto Transmission Manual Shaft Seal, S-221207

from

$6.49
Driveworks Auto Transmission Manual Shaft Seal, S-221207.
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National – National Shaft Repair Sleeve, 99145 (Part No.99145)

National Shaft Repair Sleeve, 99145

from

$33.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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Driveworks – Driveworks Manual Transmission Output Shaft Seal, S-710112 (Part No.S-710112)

Driveworks Manual Transmission Output Shaft Seal, S-710112

from

$9.49
Driveworks Manual Transmission Output Shaft Seal, S-710112.
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National – National Multi-Purpose Seal, 710112 (Part No.710112)

National Multi-Purpose Seal, 710112

from

$16.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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(3 reviews)
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National – National Automatic Transmission Output Shaft Seal, 710876 (Part No.710876)

National Automatic Transmission Output Shaft Seal, 710876

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
View Product

National – National Automatic Transmission Output Shaft Seal, 711111 (Part No.711111)

National Automatic Transmission Output Shaft Seal, 711111

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
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Driveworks – Driveworks Manual Transmission Output Shaft Seal, S-710319 (Part No.S-710319)

Driveworks Manual Transmission Output Shaft Seal, S-710319

from

$3.49
Driveworks Manual Transmission Output Shaft Seal, S-710319.
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Most Popular Manual Transmission Output Shaft Seal for 2008 Lexus RX350s

Enhance your 2008 Lexus RX350 with this popular Manual Transmission Output Shaft Seal we have in stock, for $11.99.
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Schaeffler – Schaeffler Shaft Seal, SS2416 (Part No.SS2416)

Schaeffler Shaft Seal, SS2416

from

$11.99
Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.
See More
View Product

Best-Selling 2008 Lexus RX350 Automatic Transmission Output Shaft Seals

Upgrade your RX350 with one of our 4 best-selling Automatic Transmission Output Shaft Seals, earning an average 3.5 stars rating across 3 reviews.
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National – National Multi-Purpose Seal, 710112 (Part No.710112)

National Multi-Purpose Seal, 710112

from

$16.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

(3 reviews)
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Driveworks – Driveworks Manual Transmission Output Shaft Seal, S-710112 (Part No.S-710112)

Driveworks Manual Transmission Output Shaft Seal, S-710112

from

$9.49
Driveworks Manual Transmission Output Shaft Seal, S-710112.
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National – National Automatic Transmission Output Shaft Seal, 710876 (Part No.710876)

National Automatic Transmission Output Shaft Seal, 710876

from

$8.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
View Product

National – National Shaft Repair Sleeve, 99145 (Part No.99145)

National Shaft Repair Sleeve, 99145

from

$33.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
View Product

Top-Quality Extension Housing Seals for 2008 Lexus RX350s

Choose a high-quality OEM or aftermarket Extension Housing Seal for Lexus RX350s and enjoy top-notch performance from $10.99.
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National – National Multi-Purpose Seal, 710319 (Part No.710319)

National Multi-Purpose Seal, 710319

from

$10.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
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Our Top Pick for a 2008 Lexus RX350 Pinion Seal

Invest in a durable Pinion Seal for your 2008 Lexus, knowing you’re getting trusted brands and expert craftsmanship.
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National – National Differential Pinion Seal, 710594 (Part No.710594)

National Differential Pinion Seal, 710594

from

$17.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
View Product

Top-Rated Transmission Seals and O-rings for 2008 Lexus RX350s

Make a smart move for your 2008 Lexus RX350 with products all priced from $8.49 to $11.99.
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National – National Multi-Purpose Seal, 712551 (Part No.712551)

National Multi-Purpose Seal, 712551

from

$11.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

(6 reviews)
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National – National Multi-Purpose Seal, 710419 (Part No.710419)

National Multi-Purpose Seal, 710419

from

$8.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More

(2 reviews)
View Product

National – National Multi-Purpose Seal, 221207 (Part No.221207)

National Multi-Purpose Seal, 221207

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.
See More
View Product

Top-Rated Transmission Seal Brands For Your 2008 Lexus RX350

When it comes to finding the perfect Transmission Seal for your 2008 Lexus RX350, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 3 trusted brands. We carry the most popular Transmission Seal brands including National, and more, all known for their exceptional customer ratings (average brand rating of 4.3 stars) and competitive prices, as low as $17.29. Purchasing a Transmission Seal from us here at Advance Auto Parts is a smart move for both you and your 2008 Lexus RX350, providing peace of mind with parts that meet or exceed OEM standards.

Popular National 2008 Lexus RX350 Transmission Seals

If you’re looking for a top-quality Transmission Seal for your 2008 Lexus RX350, Advance Auto Parts has exactly what you need with our selection of National Transmission Seals. We have 1 National Transmission Seals in stock for this fitment, all known for their durability and precision fit. With prices starting at just $17.29, you’ll find the perfect Transmission Seal for your needs and budget. National Transmission Seals for the 2008 Lexus RX350 come highly rated, with over 1 customer reviews and an impressive average rating of 4.3 stars. Choosing a National Transmission Seal from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
National Multi-Purpose Seal, 2025
from $17.29
(1)
National Multi-Purpose Seal, 2025
“It fit my 1998 Camry front crankshaft O-ring exactly. I can’t say how long it will last, but hopefully as long as the last one.”

FAQs for 2008 Lexus RX350 Transmission Seals

What are the best-selling Transmission Seals for 2008 Lexus RX350s?

Out of 15 Transmission Seals that fit 2008 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2008 Lexus RX350 Transmission Seals?

The prices of Transmission Seals for the 2008 Lexus RX350 range from $3.49 up to $33.99 for the most premium parts.

What is the average price of a Transmission Seal for a 2008 Lexus RX350?

The average price for Transmission Seals for the 2008 Lexus RX350 is $12.28. Keep in mind the variety of part types within our Transmission Seal category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Transmission Seals for other Lexus RX350 model years?

Yes, we carry Transmission Seals for 14 model years of Lexus RX350s between 2007 and 2022. The following model years are the most popular for Transmission Seal purchases: 2022, 2021, 2020, 2019, 2018, 2017, 2016, 2015, and 2014.

What are the cheapest Transmission Seals for my 2008 Lexus RX350?

The cheapest 2008 Lexus RX350 Transmission Seals we carry are:

Does Advance Auto Parts sell Transmission Seals for any other 2008 Lexus models?

Yes. We stock Transmission Seals for 11 other popular 2008 Lexus models. Some of the most popular are 2008 ES350 Transmission Seals, 2008 SC430 Transmission Seals, 2008 RX400H Transmission Seals, 2008 IS250 Transmission Seals, and 2008 IS350 Transmission Seals.

What are the top-rated Transmission Seals that fit the 2008 Lexus RX350?

The one 2008 Lexus RX350 Transmission Seal we have in stock is the Driveworks Manual Transmission Output Shaft Seal, S-710319. It costs $3.49.

What types of Transmission Seals do you sell for my 2008 Lexus RX350?

As of 8/2/26, these are some of the most in-demand types of Transmission Seals for a 2008 Lexus RX350:

Can I get help with 2008 Lexus RX350 Transmission Seal orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Transmission Seals and more.

What is your return policy for Lexus RX350 Transmission Seals?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Transmission Seals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

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