2006 GMC Sierra 2500 HD Engine Cooling Parts

Essential 2006 GMC Sierra 2500 HD Engine Cooling Parts

Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-104)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

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$61.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

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$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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Felpro – Engine Coolant Thermostat Housing Seal (Part No.35720)

Engine Coolant Thermostat Housing Seal

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$4.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000204873ACD)

GM Original Equipment Engine Coolant Thermostat

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$27.52
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Motorad – Coolant Housing/Water Outlet: (Part No.CH6007)

Coolant Housing/Water Outlet:

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$78.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. The construction of this housing is improved over the OE design to fix and update any issues that the OE design may have had.

Product Features:
  • Easy, one step fit and installation
  • No special tools required
  • Meets or exceeds all OEM standards
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Victor Reinz – Engine Water Pump Installation Kit (Part No.18-10020-01)

Engine Water Pump Installation Kit

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$9.49
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
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ACDelco – Relay (Part No.P2020765633ACD)

Relay

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$14.65
Relay

FAE – Engine Coolant Temperature Sensor (Part No.C6020175714FAE)

Engine Coolant Temperature Sensor

from

$23.58
The FAE Engine Coolant Temperature Sensor is an ideal high quality aftermarket replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium aftermarket replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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KAI – Cooling Fan Shroud (Part No.GM3110136)

Cooling Fan Shroud

from

$49.99
New Platinum Pro Lower Fan Shroud, V6

Product Features:
  • V6 Engines
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Felpro – THERMOSTAT GASKET (Part No.35614)

THERMOSTAT GASKET

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$5.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
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Permatex – Ultra Grey RTV Silicone Gasket Maker, 13 OZ (Part No.82195)

Ultra Grey RTV Silicone Gasket Maker, 13 OZ

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$26.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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ACDelco – Water Pump Gasket (Part No.G3040344873ACD)

Water Pump Gasket

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$10.66
ACDelco is a global leader in automotive replacement parts and related services and offers quality aftermarket products for most makes and models, including General Motors, Ford, Chrysler, Toyota and Honda. ACDelco has over 100 years of experience in the automotive industry and is a brand of GM Customer Care and After sales, a division of General Motors.
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Felpro – WATER PUMP MOUNTING GASKET SET (Part No.ES 73010)

WATER PUMP MOUNTING GASKET SET

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$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Dorman – Water Pump Outlet Pipe (Part No.626-661)

Water Pump Outlet Pipe

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$82.99
This engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles. It is engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion..

Product Features:
  • Direct replacement – this engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles.
  • Ideal solution – engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
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Carquest Premium – Radiator Cap: 15 PSI (Part No.10248)

Radiator Cap: 15 PSI

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$14.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Dorman – Engine Heater Hose Assembly (Part No.626-543)

Engine Heater Hose Assembly

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$80.99
This replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this replacement engine coolant pipe assembly is designed to match the fit and function of the original assembly on specified makes, years and models
  • Restores functionality – reliable replacement for an original part that is leaking, cracked or failed from corrosion and heat
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Engine Cooling Fan Pulley Bracket (Part No.300-826)

Engine Cooling Fan Pulley Bracket

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$271.99
This engine cooling fan pulley bracket is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine cooling fan pulley bracket matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this bracket is a reliable replacement for an original part that has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.45813)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

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$1.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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Felpro – Engine Water Pump Gasket (Part No.35756)

Engine Water Pump Gasket

from

$2.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Factory Air – Harness Connector (Part No.37231)

Harness Connector

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$26.99
OE style connectors; Molded plastic construction; Quality contacts ensure proper conductivity; Universal applications
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Motorad – Thermostat Kit: Includes Inlet, Thermostat and Seal, 187 Degrees (Part No.524KT)

Thermostat Kit: Includes Inlet, Thermostat and Seal, 187 Degrees

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$45.49
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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KAI – Radiator Support (Part No.GM1225265)

Radiator Support

from

$59.99
New Standard Replacement Radiator Support Center

Product Features:
  • Made Of Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Felpro – Engine Water Pump Gasket (Part No.35664)

Engine Water Pump Gasket

from

$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.799-105)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

from

$5.29
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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Dorman – Freeze Plug (Part No.A1030831249DOR)

Freeze Plug

from

$12.36
Dorman’s Engine Expansion Plugs are available in multiple styles, including Cup Type, Pilot Seal, Reverse Taper, Concave, Quick-Seal® Rubber and Quick-Seal ® Copper. Dorman’s uniquely designed Pilot Seal Expansion Plug ensures a leak-proof fit. Dorman also offer Engine Expansion Plug Kits.

Product Features:
  • Many sizes available
  • Conveniently available in packs of different quantities
  • Constructed from high quality steel, copper, brass, or rubber
  • Dorman’s Engine Expansion Plugs are constructed to strict engineering quality standards
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Imperial – Thermostatic Fan Control – Adjustable (Part No.226208)

Thermostatic Fan Control - Adjustable

from

$62.99
Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160°F – 210°F thread-in probe
  • For use with Imperial electric fans
  • Thread-in probe for installation in water jacket or radiator
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Imperial – Thermostatic Fan Control – Preset (Part No.226206)

Thermostatic Fan Control - Preset

from

$38.49
Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Preset thermostatic fan control
  • 185°F preset
  • For use with Imperial electric fans
  • Probe installs into radiator fins
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Imperial – Adjustable Thermostatic Fan Control (Part No.226204)

Adjustable Thermostatic Fan Control

from

$55.99
Adjustable Thermostatic Fan Control. 160-210°F; push-in probe. Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160-210°F push-in probe
  • For use with Imperial electric fans
  • Probe installs into radiator fins
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2006 GMC Sierra 2500 HD Engine Cooling Parts

Maybe you’re in the middle of a full rebuild of that 2006 GMC Sierra 2500 HD. Maybe you just need a couple of Engine Cooling Parts. Either way, Advance Auto Parts has 122 different Engine Cooling Parts in our inventory ranging from $1.79 to $551.99. That means you can find the exact parts or products you need to keep that 2006 GMC Sierra 2500 HD running smoothly.

Engine Cooling Parts are only as good as their brand. We stock 21 different brands to make sure you have plenty of trusted parts to choose from for your 2006 GMC Sierra 2500 HD. Carquest Premium, Permatex, and Felpro are just some of the brands we stock. Search for brands you know or compare prices and reviews to help you decide!

We know you’ll find the perfect Engine Cooling Parts for your 2006 GMC Sierra 2500 HD, but don’t take our word for it – read our customer ratings and reviews and buy with confidence. Out of the 14,084 reviews in this category, some of the top rated parts include Engine Water Pump Gasket with 4.7 stars and Radiator: With Engine and Transmission Oil Coolers with 4.6 stars.

So if you’re in the market for aftermarket Engine Cooling Parts to keep your 2006 GMC Sierra 2500 HD rolling for years to come, look no further. Shop online and have your products shipped direct to your door, or pick up at the nearest Advance Auto Parts location today!

Engine Cooling Parts Brands To Make Your 2006 GMC Sierra 2500 HD Last

Simple repair, complete replacement, or a full rebuild. No matter the job, your 2006 GMC Sierra 2500 HD demands trusted brand parts and products to keep it running. Many trusted brands of Engine Cooling Parts make up Advance Auto Parts’ inventory, and all are ready to help make your Sierra 2500 HD the best it can be. Be sure to browse some of our top Engine Cooling Parts brands and parts.

Popular ACDelco Engine Cooling Parts

We carry ACDelco parts in our stock across Coolant Temperature Sensors categories, plus more. For a 2006 GMC Sierra 2500 HD, our most popular ACDelco Engine Cooling Parts include:
Engine Coolant Temperature Sensor
from $34.99
(1)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors

FAQs for 2006 GMC Sierra 2500 HD Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the 2006 GMC Sierra 2500 HD?

Out of 122 Engine Cooling Parts for the 2006 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Water Pump Gaskets
Engine Water Pump
from $101.99
(345)
Engine Water Pump
Water Pumps
Standard Thermostat: With Seal, 195 Degrees
from $7.29
(105)
Standard Thermostat: With Seal, 195 Degrees
Thermostats

What are the top-rated 2006 GMC Sierra 2500 HD Engine Cooling Parts?

Top-rated Engine Cooling Parts for your 2006 GMC Sierra 2500 HD based on customer reviews/ratings are:
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
“Great product …easy to use”
Radiator: With Engine and Transmission Oil Coolers
from $269.99
(73)
Radiator: With Engine and Transmission Oil Coolers
“The Staff was real helpful the manager she liked that she’d the best ever with a perfect smile and the way she greets her and she’s so resourceful ca”
Radiator Cap: 15 PSI
from $14.99
(59)
Radiator Cap: 15 PSI
“This cap fit and worked great, no problems at all”