2001 GMC Sierra 2500 HD Cooling and Climate Controls

Essential 2001 GMC Sierra 2500 HD Cooling and Climate Controls

ACDelco – Water Pump Gasket (Part No.G3040344873ACD)

Water Pump Gasket

from

$10.76
ACDelco is a global leader in automotive replacement parts and related services and offers quality aftermarket products for most makes and models, including General Motors, Ford, Chrysler, Toyota and Honda. ACDelco has over 100 years of experience in the automotive industry and is a brand of GM Customer Care and After sales, a division of General Motors.
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ACDelco – 15-80692 GM Original Equipment Engine Cooling Fan Blade (Part No.G5050374437ACD)

15-80692 GM Original Equipment Engine Cooling Fan Blade

from

$109.23
ACDelco GM Original Equipment Engine Cooling Fan Blades are located between the radiator and engine and are GM-recommended replacements for your vehicle’s original components. The fan is a part of the engine cooling system, which moves air across the radiator and A/C condenser to remove heat from the engine cooling system and the AC refrigerant system. The fan may be belt-driven or operated by an electric motor. This cooling fan blade has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – Brake Pressure Modulator Sensor Connector (Part No.PTA1017)

Brake Pressure Modulator Sensor Connector

from

$28.49
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.45813)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

from

$1.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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Factory Air – Compressor Mounted High Cut-Out Pressure Switch (Part No.20058)

Compressor Mounted High Cut-Out Pressure Switch

from

$29.49
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Color coded for easy identification
  • Zinc coated to resist corrosion
  • Improved 2 terminal design replacing older 1 terminal switch
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Delphi – A/C Compressor (Part No.CS20039)

A/C Compressor

from

$274.99
100 years of OE experience, supplier to the world’s top automakers, OE Heritage and knowledge built into every aftermarket part.

Product Features:
  • All Delphi compressors are an exact fit
  • Sealing washers are included (where applicable) with all Delphi compressors and no extra parts to purchase
  • All Delphi compressors are 100% leak tested
  • Delphi compressors are constructed with high-quality corrosion resistant aluminum alloy not often found in aftermarket products
  • Low torque demand results in better engine performance and increased fuel economy
  • All Delphi compressors meet or exceed OE specifications
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Carquest Premium – A/C Discharge Line Hose Assembly (Part No.T56424)

A/C Discharge Line Hose Assembly

from

$85.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related air conditioning
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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KAI – A/C Evaporator Core (Part No.EVA010339)

A/C Evaporator Core

from

$134.99
New Standard Replacement A/C Evaporator Core, Front

Product Features:
  • Front, Made Of Aluminum delete
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Motorad – Standard Thermostat: With Seals, 180, 185 Degrees (Part No.447448)

Standard Thermostat: With Seals, 180, 185 Degrees

from

$40.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Imperial – Adjustable Thermostatic Fan Control (Part No.226204)

Adjustable Thermostatic Fan Control

from

$55.99
Adjustable Thermostatic Fan Control. 160-210°F; push-in probe. Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160-210°F push-in probe
  • For use with Imperial electric fans
  • Probe installs into radiator fins
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Carquest Premium – A/C Compressor Relay Connector (Part No.PTA1171)

A/C Compressor Relay Connector

from

$61.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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KAI – Valve Core/Cap Kit (Part No.FTT010103)

Valve Core/Cap Kit

from

$12.99
New Standard Replacement A/C System Valve Core And Cap Kit

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – Body Wiring Harness Connector (Part No.PTC1194)

Body Wiring Harness Connector

from

$85.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Dorman – Radiator Drain Petcocks (Part No.G10051333557DOR)

Radiator Drain Petcocks

from

$5.73
Dorman offers a variety of Radiator Drain Petcocks for a range of applications. The high-quality design ensures effective draining of the cooling system. Features and Benefits

Product Features:
  • Available in several styles, including standard, screw-in, and push-in with captive thread
  • Direct replacement Radiator Drain Petcocks available (where applicable) to ensure a proper fit
  • Durably engineered for a long service life
  • Easy to use, no need to disconnect any of the radiator hoses
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Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.438139)

Radiator: With Transmission Oil Cooler

from

$479.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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Carquest Premium – Coolant Temperature Sensor (Part No.WTC1001)

Coolant Temperature Sensor

from

$22.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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ACDelco – Heating and Air Conditioning Blower Control Module (Part No.15-8794)

Heating and Air Conditioning Blower Control Module

from

$109.99
ACDelco GM Original Equipment HVAC Blower Motor Control Modules are microprocessor computers that modulate HVAC blower speed. The control module receives input from the HVAC control module and is a GM-recommended replacement for your vehicle’s original component. This original equipment HVAC blower motor control module has been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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KAI – Coolant Reservoir (Part No.GM3014121)

Coolant Reservoir

from

$62.99
New Platinum Pro Coolant Recovery Tank, With Cap

Product Features:
  • With Cap, Made Of Plastic
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – A/C Suction Line Hose Assembly (Part No.T56465)

A/C Suction Line Hose Assembly

from

$117.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related air conditioning
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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ACDelco – A/C Hose (Part No.R1020514721ACD)

A/C Hose

from

$178.20
A/C Hose

Carquest Premium – A/C Liquid Line Hose Assembly w/ Serviceable Orifice Tube (Part No.T66050)

A/C Liquid Line Hose Assembly w/ Serviceable Orifice Tube

from

$68.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related air conditioning
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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NTK – ABS Wheel Speed Sensor (Part No.AB2017)

ABS Wheel Speed Sensor

from

$44.99
Building upon a foundation of premium full-line products established under NGK ignition and NTK oxygen sensor products, NTK’s expansion to technical sensors is part of our ongoing commitment to streamline product types and increase coverage under one premium brand: NTK, The Sensor Specialist. With over 80 years of automotive expertise, NGK’s family of automotive products are driven by extreme dedication to innovation, performance and quality. NTK is the only OE supplier with a full-line of technical sensors in the aftermarket for import and domestic vehicles. Drawing from OE experience, NTK sensors undergo extreme testing conditions that include thermal shock, vibration and OBD verification. NTK sensors are manufactured to ensure a quality that meets or exceeds OE specifications. As new vehicles incorporate connected and automated technologies, trust The Sensor Specialist for full-line market support and OE application technology.

Product Features:
  • NTK ABS Wheel Speed Sensor connectors, mounts and wire lengths are an exact match to OE for worry free installation. Grease, mounting nut and instruction sheet included where applicable.
  • NTK’s Wheel Speed Sensors are manufactured to operational performance standards to meet or exceed OE fit, form and function. Manufactured with weather pack connectors to prevent dirt and moisture contamination.
  • The ABS ECU monitors the Wheel Speed Sensors rotational speed for anti-lock brake function, stability control and traction control. The ABS sensors report the speed of all four wheels to the ECU to determine if the wheels are locking up.
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Carquest Premium – HVAC Blower Motor Resistor Connector (Part No.PTA1336)

HVAC Blower Motor Resistor Connector

from

$67.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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ACDelco – Multi-Purpose Pigtail (Part No.PT1357)

Multi-Purpose Pigtail

from

$37.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Autotecnica – Air Flap Actuator (Part No.R2046409368ANA)

Air Flap Actuator

from

$87.84
Air Flap Actuator

Permatex – Sensor-Safe, High Torque RTV Silicone Gasket Maker (Part No.22074)

Sensor-Safe, High Torque RTV Silicone Gasket Maker

from

$6.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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Dorman – Panel Trim Retainer – Interior – Ford (sold by each) (Part No.700-398)

Panel Trim Retainer - Interior - Ford (sold by each)

from

$1.29
All our Multi-Purpose Retainers are made of high quality materials for long-lasting durability. Offering a full line of Multi-Purpose Retainers for a wide range of applications.

Product Features:
  • Durable nylon design for a long service life
  • Also suitable for a broad variety of industrial and commercial uses
  • Conveniently packaged in a variety of piece counts
  • Direct replacement Retainers available (where applicable) to ensure a proper fit
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Popular 2001 GMC Sierra 2500 HD Cooling and Climate Controls Categories

2001 GMC Sierra 2500 HD Cooling and Climate Controls

You count on your 2001 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 272 Cooling and Climate Controls ranging in price from $1.29 to $1,164.38, you’re sure to find everything you need for your 2001 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 29 different brands like Carquest Premium, Permatex, and Felpro. 2001 GMC Sierra 2500 HD Cooling and Climate Controls start as low as $1.29!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 14,568 extensive product reviews on 2001 GMC Sierra 2500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Engine Cooling Fan Clutch: Reverse Rotation Severe Duty Thermal Clutch with 4.4 stars and Standard Thermostat: With Seal, 195 Degrees with 4.6 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2001 GMC Sierra 2500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2001 GMC Sierra 2500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2001 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Permatex, Felpro, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Blend Doors and Air Conditioning Parts. All are waiting to get your 2001 GMC Sierra 2500 HD back on the road. Some of the top-rated ACDelco products in these categories are:
HVAC Blend Door Actuator: 1 Piece
from $251.99
(1)
HVAC Blend Door Actuator: 1 Piece
Air Blend Door Actuators
Multi-Purpose Pigtail
from $37.99
(2)
Multi-Purpose Pigtail
AC Clutch Coil Connectors
Engine Coolant Temperature Sensor
from $34.99
(1)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2001 GMC Sierra 2500 HD, and some of our most reviewed Carquest Premium parts include:
Engine Water Pump: New, Gasket/Seals Included
from $153.99
(371)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps
Standard Thermostat: With Seal, 187 Degrees
from $18.79
(189)
Standard Thermostat: With Seal, 187 Degrees
Thermostats
Integrated Thermostat Housing: With Seal, 187 Degrees
from $23.49
(173)
Integrated Thermostat Housing: With Seal, 187 Degrees
Thermostat and Water Outlet Assemblies

FAQs for 2001 GMC Sierra 2500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2001 GMC Sierra 2500 HD?

Out of 272 Cooling and Climate Controls for the 2001 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Engine Water Pump
from $101.99
(345)
Engine Water Pump
Water Pumps
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets

What are the top-rated 2001 GMC Sierra 2500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2001 GMC Sierra 2500 HD based on customer reviews/ratings are:
Engine Cooling Fan Clutch: Reverse Rotation Severe Duty Thermal Clutch
from $95.99
(129)
Engine Cooling Fan Clutch: Reverse Rotation Severe Duty Thermal Clutch
“Good value and perfect replacement part”
Standard Thermostat: With Seal, 195 Degrees
from $7.29
(105)
Standard Thermostat: With Seal, 195 Degrees
“Replaced my old one.. No problems”
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
“Great product …easy to use”