2001 GMC Sierra 2500 HD Fluids and Chemicals

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Essential Fluids and Chemicals for 2001 GMC Sierra 2500 HDs

Valvoline – Valvoline DEX/MERC ATF Conventional Automatic Transmission Fluid, 1 Quart, 798153 (Part No.798153)

Valvoline DEX/MERC ATF Conventional Automatic Transmission Fluid, 1 Quart, 798153

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$10.99
Valvoline DEX/MERC ATF is a high-quality transmission fluid formulated to meet the challenging demands of many automatic transmissions. Its responsive low-temperature fluidity is beneficial in both electronic and hydraulic controlled transmissions and transaxles. Recommended for use in the following applications: MERCON*, DEXRON*-III, Ford M2C138-CJ and M2C166-H, Allison C-4 and TES-389, and Caterpillar TO-2. Volume: 1 quart.
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Valvoline – Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775 (Part No.773775)

Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775

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$39.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life. Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Volume: 1 gallon.
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Prestone – Prestone DOT 3 Brake Fluid: Synthetic, Prevents Corrosion, Safe For ABS, Disc, Drum Brakes, 50k miles, 12 oz., AS400 (Part No.AS400)

Prestone DOT 3 Brake Fluid: Synthetic, Prevents Corrosion, Safe For ABS, Disc, Drum Brakes, 50k miles, 12 oz., AS400

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$7.99
Prestone DOT 3 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 3. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 3 braking systems (ABS, disc or drum) and can mix with any DOT 3 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.
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Certified A/C Pro – Certified A/C Pro AC Pro P-100UV PAGOIL100 W/UVDYE (Part No.P-100UV)

Certified A/C Pro AC Pro P-100UV PAGOIL100 W/UVDYE

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$15.99
Certified A/C Pro R-134a PAG 100 Medium Viscosity Refrigerant Oil with UV Dye. This product contains approximately 8 fluid ounces of PAG Refrigerant oil with UV dye. Medium viscosity PAG oil for R-134a auto A/C systems; ISO 100 viscosity. R-134a PAG 100 Medium Viscosity AC Oil Lubricant with UV Dye features system safe UV leak detection dye. The PAG oil helps quiet noisy compressors. Meets OEM specifications.
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Prestone – Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Original Equipment North American Orange, 1 Gallon, AF6700 (Part No.AF6700)

Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Original Equipment North American Orange, 1 Gallon, AF6700

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$22.99
Prestone American Vehicles (Orange) antifreeze+coolant is specially designed to work with these specific vehicles: Ford 2002 and newer; Chrysler 2000 and newer; GM 1995 and newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, but they also protect the engine from rust, corrosion, buildup, pitting and engine damage. All of those can cause engine part failure and expensive repairs. Avoid costly repairs and vehicles in the shop with Prestone Asian vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, officially patented by Prestone. Volume: 1 gallon.
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Carquest Premium – Carquest Refrigerant Oil – PAG 150 Oil For R134a (8 Ounces), T59003 (Part No.T59003)

Carquest Refrigerant Oil - PAG 150 Oil For R134a (8 Ounces), T59003

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$17.99
This premium new compressor improves upon the original equipment design by providing two additional pistons and a center seal lip to prevent a center seal leak created by road conditions. Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure a smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.
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Valvoline – Valvoline Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 898795 (Part No.898795)

Valvoline Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 898795

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$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant €“ from the brand trusted for over 150 years. Volume: 1 quart.
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Valvoline – Valvoline 5W-30 Full Synthetic Motor Oil, Superior Temperature Performance, 5 Gallon, 881629 (Part No.881629)

Valvoline 5W-30 Full Synthetic Motor Oil, Superior Temperature Performance, 5 Gallon, 881629

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$241.49
Valvoline Full Synthetic Motor Oil delivers superior engine protection by fighting the three major causes of engine stress: heat, deposits and wear. When you want to keep your engine running its best, choose the ultimate protection found in Valvoline Full Synthetic Motor Oil. Valvoline Full Synthetic Motor Oil meets the GM(1) dexos1 Gen2 and API SN PLUS specifications, helping protect gasoline direct injected engines from low-speed pre-ignition. Volume: 5 gallons.
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Royal Purple – Royal Purple High Performance 5W-30 Synthetic Motor Oil, Better Wear Protection, 1 Quart, 01530 (Part No.01530)

Royal Purple High Performance 5W-30 Synthetic Motor Oil, Better Wear Protection, 1 Quart, 01530

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$14.49
High Performance Motor Oil API LICENSED MOTOR OIL Royal Purple High Performance Motor Oil combines premium base oils with proprietary additive technologies to create a high performance synthetic engine oil that optimizes performance and protection. Royal Purple High Performance Motor Oils carry the current API and ILSAC engine oil licenses, as well as the GM dexos1 gasoline engine oil approval. ILSAC GF-6 AND GM DEXOS1 Modern gasoline direct injection (GDI) engines have achieved levels of power and fuel economy never before possible in passenger car engines. As a result, smaller engines operate at much higher loads across all engine speeds. This has caused increased wear in critical areas of the engine, and created a destructive phenomenon called low-speed pre-ignition (LSPI). The unique, state-of-the-art additive technology in Royal Purple High Performance engine oils is designed specifically to address these issues, and help engines maintain performance and reliability. Volume: 1 quart.
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Valvoline – Valvoline Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart, 881159 (Part No.881159)

Valvoline Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart, 881159

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$29.99
Valvoline Daily Protection Motor Oil is specially formulated to exceed industry standards for wear, deposit and sludge protection to help keep engines running like new. Developed with high quality additives and premium base oils, it’s designed to flow easily at cold temperatures, reducing wear at startup and providing added protection against motor oil breakdown in tough conditions. For enhanced fuel efficiency, choose Daily Protection Synthetic Blend 5W-20 or 5W-30. Developed with low-friction technology to support strong fuel economy. Volume: 5 quarts.
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Prestone – Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 12 Oz., AS262 (Part No.AS262)

Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 12 Oz., AS262

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$9.99
Prestone Power Steering Fluid + Stop Leak (PSF+SL) delivers increased system life and prevents & stops system leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. The stop leak additives also prevent leaks by rejuvenating seals before they leak. Also designed with Anti-wear System Protection, Prestone PSF+SL protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.
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Valvoline – Valvoline ULV ATF Full Synthetic Ultra Low Viscosity Automatic Transmission Fluid, 1 Quart, 888460 (Part No.888460)

Valvoline ULV ATF Full Synthetic Ultra Low Viscosity Automatic Transmission Fluid, 1 Quart, 888460

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$18.99
Valvoline ULV ATF is the full-synthetic, ultra-low viscosity transmission fluid that has been uniquely engineered to meet and exceed the performance requirements of the latest General Motors and Ford high-speed automatic transmission with 9 and 10 speed gear configurations. Formulated with advanced additives to prevent the major causes of transmission breakdown, it€™s designed to help prevent leaks, reduce wear and tear, and maximize performance €“ all for much longer than conventional fluids. It has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and specific frictional enhancements for smooth gear engagements. The sophisticated technologies of today€™s 9 and 10 speed automatic transmissions present their own set of challenges €“ all of which were uniquely considered when we developed Valvoline ULV ATF. Valvoline ULV ATF is the best transmission fluid for the latest technology of Ford and GM vehicles with high-speed transmissions. It€™s specifically recommended for use in the following applications: Ford/GM 10R80 and select Ford F-150 and Raptor trucks. For the many shifts and miles ahead, trust your transmission with Valvoline, the #1 automatic transmission fluid brand. Volume: 1 quart.
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Valvoline – Valvoline Import Multi-Vehicle Synthetic Automatic Transmission Fluid, 1 Quart, 822389 (Part No.822389)

Valvoline Import Multi-Vehicle Synthetic Automatic Transmission Fluid, 1 Quart, 822389

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$14.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON, GM DEXRON-II and DEXRON-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III, Toyota/Lexus Type T, T-III and T-IV, Honda/Acura ATF-Z1 (except in CVTs), Mercedes Benz NAG1, Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid. Volume: 1 quart.
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Powertrax – Powertrax Differential Lock Assembly, 1950-LR (Part No.1950-LR)

Powertrax Differential Lock Assembly, 1950-LR

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$487.99
For vehicles that are driven daily, the Power Trax No-Slip Traction System is the latest design in quiet traction-adding differential technology. It combines the automatic street-friendly smooth operation of a limited-slip differential with the traction performance of a locking differential. The Power Trax No-Slip locker easily installs in to your differential carrier using basic tools and without affecting your ring and pinion settings. Power Trax Grip-Lok, Lock-Right Lockers and No-Slip Traction Systems automatically provide 100% traction on-demand, under the toughest circumstances. The Power Trax Grip-Pro and Grip-LS performance limited slips offer smooth dependable torque transfer and traction for the best of both worlds.
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Yukon Gear – "Yukon Gear Grizzly Locker For GM & Chrysler 11.5"" With 30 Spline Axles, 28013" (Part No.28013)

"Yukon Gear Grizzly Locker For GM & Chrysler 11.5"" With 30 Spline Axles, 28013"

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$1749.99
The Yukon Grizzly Locker is the ultimate in locking differentials for street, off-road, & drag racing. Grizzly Lockers provide 100% power to both tires, while still allowing for disengagement while negotiating turns. The Yukon Grizzly locker is a mechanical locking differential. It features a forged case and 8620 internals for maximum strength. It’s patented design reduces common locker failures. All units assembled in the USA! All Grizzly Lockers are backed by the best warranty in the business! Yukon covers the replacement unit and covers any collaterally damaged parts and associated labor, up to $2,000!
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Permatex – Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195 (Part No.82195)

Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195

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$29.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.
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Permatex – Permatex Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ, 22071 (Part No.22071)

Permatex Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ, 22071

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$8.49
Permatex Water Pump & Thermostat RTV Silicone Gasket Maker is a noncorrosive, sensor-safe RTV silicone gasket material formulated for water pumps and thermostat housings. Permatex Water Pump & Thermostat has the highest water-glycol resistance available in an RTV silicone.
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Certified A/C Pro – Certified A/C Pro R134a PAG 46 Oil Charge w/ICE32, PC-1V (Part No.PC-1V)

Certified A/C Pro R134a PAG 46 Oil Charge w/ICE32, PC-1V

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$11.99
Certified A/C Pro R-134a PAG 46 Oil Charge with ICE 32 for improved cooling (3 ounces). This product contains approximately 1 oz. of PAG 46 Oil Charge, approximately 1 oz. of R134a Refrigerant and approximately 1oz of ICE32 Performance Enhancer. A/C Pro R-134a PAG 46 AC Oil Lubricant with ICE 32 features advanced chemistry for improved cooling while extending compressor life. The PAG oil helps quiet noisy compressors.
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Certified A/C Pro – Certified A/C Pro R134a PAG 150 Oil Charge w/ICE32, PC-3V (Part No.PC-3V)

Certified A/C Pro R134a PAG 150 Oil Charge w/ICE32, PC-3V

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$11.99
Certified A/C Pro R134a PAG 150 Oil with ICE 32. High viscosity PAG oil for R134a auto air conditioning. Contains 1oz PAG 150 viscosity oil charge with Oil Composition Air Conditioning Polyalkylene Glycol (PAG). Also contains 1 oz. of ICE 32 lubricant performance enhancer. R-134a PAG 150 AC Oil Lubricant with ICE 32 features advanced chemistry for improved cooling while extending compressor life. The PAG oil helps quiet noisy compressors. Meets OEM specifications.
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Castrol – Castrol Autran Syn-295 Synthetic Transmission Fluid, 1 Gallon, 709732 (Part No.709732)

Castrol Autran Syn-295 Synthetic Transmission Fluid, 1 Gallon, 709732

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$71.99
Autran Syn-295 Synthetic Transmission Fluid is a premium full-synthetic solution designed for heavy-duty automatic transmissions, meeting the rigorous Allison TES-295 and TES-468 standards. Engineered with high-viscosity index synthetic base fluids and advanced additives, it delivers exceptional wear protection, superior high and low-temperature performance, and outstanding shear stability. This fluid keeps transmissions cooler, resists oxidation, and offers excellent corrosion and foaming resistance, ensuring long-lasting reliability even under extreme operating conditions. Compatible with a wide range of OEM systems, including Allison C-4, Voith, and ZF transmissions, it is ideal for light-duty applications such as buses, emergency vehicles, delivery trucks, motor homes, and more. Whether for on- or off-highway use, this 1-gallon solution provides unmatched durability and performance, making it a trusted choice for demanding environments. Volume: 1 gallon.
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Valvoline – Valvoline MaxLife Multi-Vehicle Full Synthetic Automatic Transmission Fluid (ATF), 5 Gallon Box, 881051 (Part No.881051)

Valvoline MaxLife Multi-Vehicle Full Synthetic Automatic Transmission Fluid (ATF), 5 Gallon Box, 881051

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$126.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life. Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA. Volume: 5 gallons.
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Pentosin – Pentosin Automatic Transmission Fluid – 5 Liter Bottle, 1058207 (Part No.1058207)

Pentosin Automatic Transmission Fluid - 5 Liter Bottle, 1058207

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$131.99
Pentosin Automatic Transmission Fluid – 5 Liter Bottle, 1058207.
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FRAM – FRAM Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon, F301 (Part No.F301)

FRAM Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon, F301

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$13.99
FRAM Extended Life AMAM Concentrate is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. FRAM Concentrate meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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FRAM – FRAM Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, F501 (Part No.F501)

FRAM Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, F501

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$16.99
FRAM Orange Concentrate is formulated for cars and light duty trucks that use Orange extended life coolant. FRAM Orange Concentrate meets or exceeds ASTM D3306 and D4985 standards for corrosion protection, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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ZEREX – ZEREX G40« 50/50 Pre-Diluted Ready-to-Use Antifreeze / Coolant, 1 Gallon, 861399 (Part No.861399)

ZEREX G40« 50/50 Pre-Diluted Ready-to-Use Antifreeze / Coolant, 1 Gallon, 861399

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$24.99
ZEREX G40® Antifreeze/Coolant provides unsurpassed protection for vehicles requiring genuine G40 and G12++ fluid. This Original Equipment Manufacturer (OEM) approved formula ensures you are getting the precise factory-filled original formula for your European vehicle. ZEREX G40 is a premium grade, long-life coolant that employs nitrite, amine and phosphate-free, Si-organic acid technology (Si-OAT) to protect the cooling system from rust and corrosion. ZEREX G40 chemistry will not void vehicle manufacturer warranty. Provides protection for 5 years / 150,000 miles in light duty applications and 3 years / 300,000 miles in heavy duty applications. Dont just use any coolant, use the chemistry specified by the manufacturer: Use ZEREX. Volume: 1 gallon.
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Mobil 1 – Mobil 1 Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart, 25201 (Part No.25201)

Mobil 1 Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart, 25201

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$12.99
Mobil 1 Synthetic ATF is a multi-vehicle, fully synthetic automatic transmission fluid that helps to improve overall transmission durability and cleanliness. Has exceptional thermal and oxidation stability and long-term frictional properties that help to improve and extend transmission efficiency, smooth shifting performance, and fuel economy. Mobil 1 ATF provides excellent low-temperature fluidity to promote reliable lubrication at temperatures down to -51C, and exceptional shear stability to help supports viscosity retention under the most severe heavy-duty, high-temperature operating conditions. Compatible with mineral ATF fluids and all common seal materials to help provide excellent leakage control and reduce concern in top-off emergencies. Meets or exceeds the requirements of JASO 1-A and Ford MERCON V. For more information, visit us at Mobil.US. Volume: 1 quart.
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Upgrade your 2001 GMC Sierra 2500 HD with Top-Quality Fluids and Chemicals

When it comes to maintaining or upgrading your 2001 GMC Sierra 2500 HD, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your GMC or enhancing its overall performance, Fluids and Chemicals are key to keeping your Sierra 2500 HD functioning at its best. At Advance Auto Parts, we offer a wide selection of 100 Fluids and Chemicals for the 2001 GMC Sierra 2500 HD, designed to meet your needs without breaking the bank. From Fluid replacements to Coolant/Antifreeze upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Fluids and Chemicals for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Fluids and Chemicals for your 2001 GMC Sierra 2500 HD at great prices. Our Fluids and Chemicals inventory for this model ranges from just $1.95 to $1,749.99, with an average price of $60.70. Our 100 Fluids and Chemicals in stock come from 19 trusted brands, so you’re sure to find the right part for your 2001 GMC Sierra 2500 HD without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2001 GMC Sierra 2500 HD, we stock popular OEM and aftermarket Fluids and Chemicals from top names like Prestone, Permatex, Certified A/C Pro, and more. Prestone Fluids and Chemicals start at just $14.99 and boast an impressive 4.8 stars average rating from customers. Permatex and Certified A/C Pro also bring quality to the table, with Fluids and Chemicals available starting at $6.99, and at an average 4.7 stars rating. With 72,132 customer reviews and counting, our 2001 GMC Sierra 2500 HD Fluids and Chemicals have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Fluids and Chemical upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2001 GMC Sierra 2500 HD is always ready to roll. We’re committed to providing you with everything you need to keep your Sierra 2500 HD in top shape, all in one place. Start shopping confidently below for your 2001 GMC Sierra 2500 HD!

Best-Selling Fluids for 2001 GMC Sierra 2500 HDs

Enhance the driving experience in your GMC with 42 quality Fluid components, starting at $6.99.

Valvoline – Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775 (Part No.773775)

Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775

from

$39.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life. Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Volume: 1 gallon.
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Mobil 1 – Mobil 1 Extended Performance Full Synthetic Motor Oil 5W-30, 5 Quart, 14977 (Part No.14977)

Mobil 1 Extended Performance Full Synthetic Motor Oil 5W-30, 5 Quart, 14977

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$48.99
Mobil 1 Extended Performance motor oil utilizes our signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles of all ages. Specialty components in synthetic oil extend engine life by reducing deposits and sludge buildup – keeping critical engine parts clean and protected for up to 25,000 miles between oil changes.(1) Mobil 1 Extended Performance motor oil meets ILSAC GF-7 standards, offering superior oxidation control, enhanced protection against pre-ignition and timing chain wear, and excellent cold-start and low-temperature performance. Mobil 1 is the No. 1 selling motor oil in America at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR(R). (1)Protects for 25,000 miles or 1 year, whichever comes first (2)Source: Circana/ Retail Tracking Service/ Dollar Sales/ 52 weeks ending February 1, 2025 (3)vs GF-7 fuel economy requirement Volume: 5 quarts.
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Shell – Shell T6 15W-40 Full Synthetic Diesel Engine Oil, Protects Against Wear, 1 Gallon, 550050467 (Part No.550050467)

Shell T6 15W-40 Full Synthetic Diesel Engine Oil, Protects Against Wear, 1 Gallon, 550050467

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$41.99
Shell Rotella T6 15W-40 diesel engine oil is a full synthetic motor oil that features exclusive Triple Protection Plus technology, formulated with fully synthetic base oils plus advanced additives to protect against wear, deposits, and oil breakdown. It offers better cold cranking properties and low-temperature pumpability at -15C compared to conventional and synthetic blend Shell Rotella 15W-40 products. It also delivers improved wear performance versus API CJ-4 technology, extended drain capabilities for more uptime, improved protection against oxidation for increased fuel economy, compatibility with exhaust emissions control systems, and protection in extreme operating conditions and climates. Shell Rotella T6 15W-40 is suitable for use in new and older diesel-powered vehicles, from Class 8 tractor/trailers to heavy-duty pickups and delivery, utility, and school bus fleets. Shell Rotella T6 is backed by a limited warranty valid up to 15 years or 500,000 miles (whichever comes first), guaranteed. (Shell Rotella Limited Warranty: Up to 15 years or 500,000 miles, whichever comes first, guaranteed, if you exclusively use Shell Rotella T6 Full Synthetic heavy-duty engine oil and meet enrollment mileage and vehicle manufacture date requirements. Enrollment required. Keep your receipts. Other conditions apply. See Rotella.com/warranty to enroll and for full details and terms.) Volume: 1 gallon.
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Valvoline – Valvoline DEXRON-VI / MERCON LV ATF Full Synthetic Automatic Transmission Fluid, 1 Gallon, 883572 (Part No.883572)

Valvoline DEXRON-VI / MERCON LV ATF Full Synthetic Automatic Transmission Fluid, 1 Gallon, 883572

from

$41.99
Valvoline DEXRON-VI / MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, MERCON LV and Allison C-4. Volume: 1 gallon.
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Valvoline – Valvoline High Mileage 5W-30 Synthetic Blend Motor Oil, Prevents Engine Breakdown, 5 Quart, 881163 (Part No.881163)

Valvoline High Mileage 5W-30 Synthetic Blend Motor Oil, Prevents Engine Breakdown, 5 Quart, 881163

from

$35.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly. Volume: 5 quarts.
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Prestone – Prestone DOT 3 Brake Fluid, 32 oz., AS401 (Part No.AS401)

Prestone DOT 3 Brake Fluid, 32 oz., AS401

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$14.99
Prestone DOT 3 Motor Vehicle Brake delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 3. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system. This formula is safe to use in all DOT 3 braking systems (ABS, disc or drum) and can mix with any DOT 3 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.
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Valvoline – Valvoline Advanced Full Synthetic 5W-30 Motor Oil, Maximizes Engine Life, 5 Quart, 881164 (Part No.881164)

Valvoline Advanced Full Synthetic 5W-30 Motor Oil, Maximizes Engine Life, 5 Quart, 881164

from

$41.99
Today’s advanced engine technology requires advanced protection. Valvoline Advanced Full Synthetic, the motor oil designed to protect today’s sophisticated engines, contains premium anti-wear additives, superior antioxidants and extra detergents. It protects 40% better against wear, resists oil breakdown 10-times better, and defends 25% more against deposits than industry standards for maximum performance and engine longevity. And with an exceptional range of temperature protection your engine will ready for extreme weather. Valvoline invented motor oil 150 years ago, and we’ve been reinventing it ever since. Get Valvoline Advanced Full Synthetic and give your engine the advanced protection proven to maximize engine life. Volume: 5 quarts.
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Valvoline – Valvoline DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 822405 (Part No.822405)

Valvoline DEXRON - VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 822405

from

$15.99
Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, and Allison C-4. Volume: 1 quart.
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Prestone – Prestone Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 Oz., AS261Y/1 (Part No.AS261Y/1)

Prestone Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 Oz., AS261Y/1

from

$13.99
Prestone Power Steering Fluid (PSF) delivers increased system life. Designed with Anti-wear System Protection, Prestone PSF protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.
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Mobil 1 – Mobil 1 High Mileage Full Synthetic Motor Oil 5W-30, 1 Quart, 14999 (Part No.14999)

Mobil 1 High Mileage Full Synthetic Motor Oil 5W-30, 1 Quart, 14999

from

$13.49
Mobil 1 High Mileage motor oil utilizes our signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles of all ages. Specialty components in synthetic oil extend engine life by reducing the friction that causes deposits and sludge buildup – keeping critical engine parts clean and protected for up to 15,000 miles between oil changes.(1) Mobil 1 High Mileage motor oil meets ILSAC GF-7 standards, offering superior oxidation control, enhanced protection against pre-ignition and timing chain wear, and excellent cold-start and low-temperature performance. Mobil 1 is the No. 1 selling motor oil in America at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR(R). Volume: 1 quart.
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Castrol – Castrol EDGE 5W-30 Advanced Full Synthetic motor oil, 1 Quart, 152C3C (Part No.152C3C)

Castrol EDGE 5W-30 Advanced Full Synthetic motor oil, 1 Quart, 152C3C

from

$13.99
Castrol EDGE 5W-30 is one of Castrol’s strongest oils and has been formulated to provide Superior Performance and Protection in 7 Critical Areas including fuel economy, high temperature performance, sludge control and wear protection for up to 20,000 miles between oil changes. Today’s engines are smaller, more powerful and under more pressure than ever before. Castrol EDGE has been engineered to withstand the intense friction of modern engines and provides 10X better high stress performance than the latest industry standard. Peak engine loads and extreme temperature can break down weaker lubricants, so viscosity control is the ultimate measure of strength for any motor oil. Castrol EDGE has been proven 3X stronger against viscosity breakdown than the leading full synthetic so its shear stable and maintains its initial viscosity to provide protection over an extended drain cycle of up to 20,000 miles between oil changes. Stronger for Longer. Volume: 1 quart.
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Valvoline – Valvoline Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart, 881159 (Part No.881159)

Valvoline Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart, 881159

from

$29.99
Valvoline Daily Protection Motor Oil is specially formulated to exceed industry standards for wear, deposit and sludge protection to help keep engines running like new. Developed with high quality additives and premium base oils, it’s designed to flow easily at cold temperatures, reducing wear at startup and providing added protection against motor oil breakdown in tough conditions. For enhanced fuel efficiency, choose Daily Protection Synthetic Blend 5W-20 or 5W-30. Developed with low-friction technology to support strong fuel economy. Volume: 5 quarts.
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Mobil Delvac – Mobil Delvac 1300 Super 15W-40 Synthetic Blend Diesel Engine Oil, Extends Engine Life, 1 Gallon, 44819 (Part No.44819)

Mobil Delvac 1300 Super 15W-40 Synthetic Blend Diesel Engine Oil, Extends Engine Life, 1 Gallon, 44819

from

$22.99
Mobil Delvac 15W-40 are extra high performance diesel engine oils that help extend engine life in the most severe on And off-highway applications while delivering outstanding performance in modern, high-output, low-emission engines including those with Exhaust Gas Recirculation And Aftertreatment Systems with Diesel Particulate Filters And Diesel Oxidation Catalysts. Fully backwards compatible, Mobil Delvac will also deliver the same exceptional performance in older conventional engines. As a result, they meet or exceed the requirements of the API CJ-4, CI-4 PLUS And CH-4 service categories as well as key Original Equipment Manufacture requirements for 2007 engines. Volume: 1 gallon.
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Valvoline – Valvoline DEX/MERC Automatic Transmission Fluid, 1 Gallon, 773636 (Part No.773636)

Valvoline DEX/MERC Automatic Transmission Fluid, 1 Gallon, 773636

from

$37.99
Valvoline DEX/MERC ATF is a high-quality transmission fluid formulated to meet the challenging demands many automatic transmissions. Its responsive low-temperature fluidity is beneficial in both electronic and hydraulic controlled transmissions and transaxles. Recommended for use in the following applications: MERCON®, DEXRON®-III, Ford M2C138-CJ and M2C166-H, Allison C-4 and TES-389, and Caterpillar TO-2. Volume: 1 gallon.
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Valvoline – Valvoline Advanced Full Synthetic 5W-30 Engine Oil, Maximizes Engine Life, 1 Quart, VV955 (Part No.VV955)

Valvoline Advanced Full Synthetic 5W-30 Engine Oil, Maximizes Engine Life, 1 Quart, VV955

from

$13.49
Today’s advanced engine technology requires advanced protection. Valvoline Advanced Full Synthetic, the motor oil designed to protect today’s sophisticated engines, contains premium anti-wear additives, superior antioxidants and extra detergents. It protects 40% better against wear, resists oil breakdown 10-times better, and defends 25% more against deposits than industry standards for maximum performance and engine longevity. And with an exceptional range of temperature protection your engine will ready for extreme weather. Valvoline invented motor oil 150 years ago, and we’ve been reinventing it ever since. Get Valvoline Advanced Full Synthetic and give your engine the advanced protection proven to maximize engine life. Volume: 1 quart.
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Shell – Shell T5 15W-40 Synthetic Blend Diesel Engine Oil, Protects Against Wear, 2.5 Gallon, 550046213 (Part No.550046213)

Shell T5 15W-40 Synthetic Blend Diesel Engine Oil, Protects Against Wear, 2.5 Gallon, 550046213

from

$79.99
Shell Rotella T5 15W-40 Synthetic Blend diesel engine oil with Triple Protection Plus technology uses synthetic base oils plus advanced additive technology to provide protection against wear, deposits, and oil breakdown. Triple Protection Plus technology offers better low-temperature flow, which delivers excellent equipment protection, long engine life, and maintains viscosity control under high temperatures. The premium synthetic base oil components help improve cold starting and low-temperature performance without compromising engine protection or durability. Shell Rotella T5 15W-40 goes beyond CK-4 wear limits, delivering an average of 37% better than the maximum wear requirements (calculated average based on API CK-4 wear test results). It’s suitable for a wide range of heavy-duty engine applications, and is an excellent choice for on-highway fleets, construction, agriculture, and diesel pick-up trucks, including high-power vehicles where resistance to increased heat and stress is required. (Shell Rotella Limited Warranty: Valid up to 10 years or 300,000 miles (whichever comes first) if you exclusively use Shell Rotella T5 Synthetic Blend heavy-duty engine oil. Terms and conditions apply. See Rotella.Shell.com/warranty for details.) Volume: 5 gallons.
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Idemitsu – Idemitsu Type HP Automatic Transmission Fluid, 1 Quart, 30040099-75000C (Part No.30040099-75000C)

Idemitsu Type HP Automatic Transmission Fluid, 1 Quart, 30040099-75000C

from

$13.99
Formulated to meet the specific requirements of Subaru vehicles equipped with conventional (non-CVT) transmissions up to model year 2005. Recommended for service-fill in all Subaru automatic transmissions where SUBARU ATF HP is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. Idemitsu is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. Idemitsu application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made. Volume: 1 quart.
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Quaker State – Quaker State 5W-30 Full Synthetic Motor Oil, Maximizes Horsepower, 5 Quart, 550046194 (Part No.550046194)

Quaker State 5W-30 Full Synthetic Motor Oil, Maximizes Horsepower, 5 Quart, 550046194

from

$34.49
Quaker State Full Synthetic 5W-30 motor oil provides strong engine performance and protection against deposits between oil changes. It’s ideal for use in today’s technologically advanced engines and high-performance vehicles like sports cars, SUVs, trucks, and minivans. It is compatible with biofuels ranging from E10 to E85 and is suitable for hybrid vehicles. Designed to deliver more power and less friction, Quaker State Full Synthetic helps to maximize horsepower. It provides excellent lubrication in both high and low temperatures and maintains the viscosity from start to finish, offering optimal protection. Better for severe driving conditions than conventional and synthetic blend oils, Quaker State Full Synthetic protects against the formulation of sludge and other harmful deposits and provides improved fuel economy. For a full list of equipment approvals and recommendations, please consult your local Quaker State Technical Help Desk and always consult your owner’s manual. Volume: 5 quarts.
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Mobil Delvac – Mobil Delvac Delvac 1300 Super 15W-40 Diesel Engine Oil, Extends Engine Life, 5 Gallon, 44823 (Part No.44823)

Mobil Delvac Delvac 1300 Super 15W-40 Diesel Engine Oil, Extends Engine Life, 5 Gallon, 44823

from

$112.99
Mobil Delvac 1300 Super 15W-40 is a premium synthetic blend diesel engine oil that helps extend engine life for diesel vehicles and equipment. Volume: 5 gallons.
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Quaker State – Quaker State 5W-30 Synthetic Blend Motor Oil, Reduces Engine Wear, 5 Quart, 550044963 (Part No.550044963)

Quaker State 5W-30 Synthetic Blend Motor Oil, Reduces Engine Wear, 5 Quart, 550044963

from

$26.99
Quaker State 5W-30 motor oil is a synthetic blend formulation that helps engines survive daily commutes from high-speed highway operation to repetitive, stop-and-go driving. It maintains the required viscosity from start to finish, providing optimal protection. Quaker State Motor Oil combats engine sludge and deposits, providing rust protection from harmful acids generated by engine contaminants. It reduces engine wear, providing durable wear protection. Quaker State 5W-30 Motor Oil meets or exceeds the following OEM requirements: Chrysler MS-6395; Ford WSS M2C946-A, Ford WSS M2C946-B1; GM 6094M. It exceeds the requirements of the following industry specifications: API SP and all previous categories; ILSAC GF-6a and all previous ILSAC standards. For a full list of equipment approvals and recommendations, please consult your local Quaker State Technical Help Desk and always consult your owner’s manual. Volume: 5 quarts.
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Prestone – Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz., AS263Y (Part No.AS263Y)

Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz., AS263Y

from

$15.99
Prestone Power Steering Fluid + Stop Leak (PSF+SL) delivers increased system life and prevents & stops system leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. The stop leak additives also prevent leaks by rejuvenating seals before they leak. Also designed with Anti-wear System Protection, Prestone PSF+SL protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.
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Shell – Shell T4 Triple Protection 15W-40 Synthetic Blend Diesel Engine Oil, 2.5 Gallon, 550045127 (Part No.550045127)

Shell T4 Triple Protection 15W-40 Synthetic Blend Diesel Engine Oil, 2.5 Gallon, 550045127

from

$64.99
T4 Triple Protection 15W-40 Synthetic Blend Diesel Engine Oil delivers advanced performance for diesel engines, combining cutting-edge technology with the trusted durability of Triple Protection®. This synthetic blend is engineered to provide enhanced protection against oxidation, wear, and deposits, ensuring your engine stays cleaner and operates more efficiently. Designed for heavy-duty applications, it sustains emission control system durability in particulate filters and after-treatment systems, making it ideal for modern diesel engines. With its SAE 15W-40 weight, this oil adapts to demanding driving conditions, offering reliable performance and long-lasting protection. Perfect for those who rely on their engines for hard work, this 2.5-gallon solution ensures value and peace of mind with every use. Volume: 5 gallons.
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Prestone – Prestone DOT 3 Brake Fluid: Synthetic, Prevents Corrosion, Safe For ABS, Disc, Drum Brakes, 50k miles, 12 oz., AS400 (Part No.AS400)

Prestone DOT 3 Brake Fluid: Synthetic, Prevents Corrosion, Safe For ABS, Disc, Drum Brakes, 50k miles, 12 oz., AS400

from

$7.99
Prestone DOT 3 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 3. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system.  This formula is safe to use in all DOT 3 braking systems (ABS, disc or drum) and can mix with any DOT 3 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.
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Shell – Shell T4 Triple Protection 15W-40 Diesel Engine Oil, Enhanced Oxidation Protection, 5 Gallon, 550045128 (Part No.550045128)

Shell T4 Triple Protection 15W-40 Diesel Engine Oil, Enhanced Oxidation Protection, 5 Gallon, 550045128

from

$119.99
T4 Triple Protection 15W-40 Diesel Engine Oil delivers advanced performance for hardworking diesel engines, combining cutting-edge technology with proven reliability. This synthetic blend oil is specifically engineered for diesel engines, offering enhanced protection against oxidation, wear, and deposits to ensure optimal cleanliness and efficiency. Its improved formula sustains emission control system durability, making it ideal for vehicles equipped with particulate filters and after-treatment systems. Designed to adapt to demanding driving conditions, this 15W-40 oil provides superior protection for heavy-duty applications while promoting smoother operation and extended engine life. With a 5-gallon capacity, it delivers exceptional value for fleet operators and individual users seeking dependable performance and long-term durability. Volume: 5 gallons.
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Most Popular 2001 GMC Sierra 2500 HD Coolant/Antifreezes

Customize your GMC with 18 Coolant/Antifreeze products like Engine Coolant and Antifreeze, all priced under $23.99.

Prestone – Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Dex-Cool Compatible, 1 Gallon, AF850 (Part No.AF850)

Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Dex-Cool Compatible, 1 Gallon, AF850

from

$19.99
Prestone DEX-COOL (Ready to use) antifreeze+coolant is specially designed to work with these specific vehicles: All GM vehicles 1995 and newer (GM approved), most Ford vehicles 2011 – 2018 and most Chrysler vehicles 2013 and newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, they also protect the engine from rust and corrosion. This fluid is designed to last 5yrs/150,000 miles. Volume: 1 gallon.
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Prestone – Prestone Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, AF888 (Part No.AF888)

Prestone Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, AF888

from

$23.99
Prestone DEX-COOL (concentrate) antifreeze+coolant is specially designed to work with these specific vehicles: All GM vehicles 1995 and newer (GM approved), most Ford vehicles 2011 – 2018 and most Chrysler vehicles 2013 and newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, they also protect the engine from rust and corrosion. This fluid is designed to last 5yrs/150,000 miles. Volume: 1 gallon.
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Prestone – Prestone Antifreeze And Coolant: 50/50 Ready-To-Use, Universal, Protects Against Corrosion, 1 Gallon, AF2100 (Part No.AF2100)

Prestone Antifreeze And Coolant: 50/50 Ready-To-Use, Universal, Protects Against Corrosion, 1 Gallon, AF2100

from

$15.49
Prestone All Vehicles antifreeze+coolant (ready to use) is truly designed to work with all vehicles; all makes, models, years & fluid colors. It is designed to work with all new engines while also being backwards compatible improving protection in all older engines. The patented Cor-Guard technology (the best innovation in the category in decades) instantly protects parts from corrosion, buildup, pitting, scaling, rust and other damage. These fluids are specially designed to not only manage the engine temp and protect from freezing up (like competitors), but they also potect the engine from damage. Internal damage can cause engine part failure, leading to expensive repairs and serious inconveniences . Avoid costly repairs and vehicles in the shop with Prestone All Vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, offically patented by Prestone. Volume: 1 gallon.
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Prestone – Prestone Antifreeze And Coolant: Concentrate, Universal, Protects Against Buildup & Rust, 1 Gallon, AF2000 (Part No.AF2000)

Prestone Antifreeze And Coolant: Concentrate, Universal, Protects Against Buildup & Rust, 1 Gallon, AF2000

from

$19.49
Prestone All Vehicles antifreeze+coolant (concentrate) is truly designed to work with all vehicles; all makes, models, years & fluid colors. It is designed to work with all new engines, while also being backwards compatible improving protection in all older engines. The patented Cor-Guard technology (the best innovation in the category in decades) instantly protects parts from corrosion, buildup, pitting, scaling, rust and other damage. Prestone’s Antifreeze + Coolants are designed to the highest standards using state of the art technology. These fluids are specially designed to not only manage the engine temp and protect from freezing up (like competitors), but they also protect the engine from damage. internal damage can cause engine part failure, expensive repairs and serious inconveniences . Avoid costly repairs and vehicles in the shop with Prestone All Vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, offically patented by Prestone. Volume: 1 gallon.
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FRAM – FRAM Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon, F301 (Part No.F301)

FRAM Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon, F301

from

$13.99
FRAM Extended Life AMAM Concentrate is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. FRAM Concentrate meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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PEAK – PEAK Antifreeze + Coolant, Concentrate, 1 Gallon, PKP0B3 (Part No.PKP0B3)

PEAK Antifreeze + Coolant, Concentrate, 1 Gallon, PKP0B3

from

$19.79
PEAK Antifreeze + Coolant Concentrate is specially engineered to deliver guaranteed superior lifetime protection. Its advanced universal formula contains a proprietary blend of 10X the scale-fighting inhibitors coupled with robust organic additives to fight against the damaging effects of scale deposits and corrosion. PEAK Antifreeze + Coolant is free of 2-EHA, silicate, nitrite, borate, and amines, ensuring maximum cooling system performance for 10 years/300,000 miles. It is compatible for use with any color or type of antifreeze/coolant in the system. Volume: 1 gallon.
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PEAK – PEAK OE North American Orange Antifreeze Plus Coolant, 1 Gallon, NAOB53 (Part No.NAOB53)

PEAK OE North American Orange Antifreeze Plus Coolant, 1 Gallon, NAOB53

from

$22.49
PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES is a line of premium coolants specifically designed to match the technology and color requirements of North American vehicles. Each coolant is formulated with the same corrosion inhibitor technology that protected your vehicle straight from the factory. Color cues on the packaging and a list of covered vehicles on the front label make it easy to identify the right match for your specific vehicle. PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES – ORANGE is an extended life antifreeze/coolant based on proprietary state-of-the-art organic acid technology (OAT). The ethylene glycol-based formula represents a carefully balanced mixture of organic acid corrosion inhibitors for complete protection of modern high-performance North American vehicle engines. It can be mixed with any DEX-COOL approved formulations in newer GM, Opel, Daewoo and Saab vehicles, as well as with antifreeze/coolant in Ford and Chrysler vehicles requiring an orange type product. This product’s orange color distinguishes its unique chemistry and ensures easy selection for North American vehicles requiring this type and color of coolant. PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES – ORANGE is free of silicate, borate, phosphate, nitrite, and amines, and is fully compatible with other extended life coolants. It meets the performance requirements of ASTM D3306 and D4985. When installed as part of a complete flush and coolant fill, PEAK guarantees this coolant will provide service life protection of up to 150,000 miles or 5 years. Volume: 1 gallon.
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FRAM – FRAM All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon, F401 (Part No.F401)

FRAM All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon, F401

from

$10.99
FRAM Extended Life AMAM 50/50 is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with FRAM Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. FRAM 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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FRAM – FRAM Antifreeze & Coolant: 50/50 Ready-to-Use, Dex-Cool Compatible, Corrosion Protection, 1 Gallon, F601 (Part No.F601)

FRAM Antifreeze & Coolant: 50/50 Ready-to-Use, Dex-Cool Compatible, Corrosion Protection, 1 Gallon, F601

from

$13.99
FRAM Orange 50/50 is formulated for cars and light duty trucks that use Orange extended life coolant. Top-off your cooling system with FRAM Orange 50/50, which is a blend of 50% antifreeze and 50% demineralized water. FRAM Orange 50/50 meets or exceeds ASTM D3306 and D4985 standards for corrosion protection, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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FRAM – FRAM Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, F501 (Part No.F501)

FRAM Antifreeze & Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon, F501

from

$16.99
FRAM Orange Concentrate is formulated for cars and light duty trucks that use Orange extended life coolant. FRAM Orange Concentrate meets or exceeds ASTM D3306 and D4985 standards for corrosion protection, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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Prestone – Prestone Antifreeze and Coolant: Concentrate, Universal Platinum, Protects Against Corrosion, 1 Gallon, AF2500 (Part No.AF2500)

Prestone Antifreeze and Coolant: Concentrate, Universal Platinum, Protects Against Corrosion, 1 Gallon, AF2500

from

$22.99
Prestone Platinum antifreeze+coolant is Prestone’s best universal antifreeze and coolant product. Guaranteed to work with all vehicles; all makes, models, years and fluid colors. 15+ years, 350,000 miles of protection; the fluid is Guaranteed for the life of your vehicle. This advanced product delivers Extreme Protection against both freezing temperatures (-50 deg.) and overheating/boiling over of the engine (+268 deg.). Prestone Platinum utilizes industry leading protection from engine damaging rust, corrosion, buildup and scale. While ordinary antifreeze coolant only focuses on the basic corrosion coverage, Prestone Platinum goes farther, adding our most advanced cooling system protection, allowing the system to run optimally, like when it was new. Internal buildup and corrosion damage can cause engine part failure or clogging, leading to expensive repairs and inconveniences. Prestone Platinum helps you avoid costly repairs and vehicles in the shop. This extended life coolant is Guaranteed to work with all new engines and engine technology, while also being backwards compatible, improving protection in all older engines. Prestone Platinum antifreeze+coolant – Year Round Protection. Volume: 1 gallon.
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Prestone – Prestone MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon, AF2800 (Part No.AF2800)

Prestone MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon, AF2800

from

$21.99
All Antifreeze + Coolants are not the same. Prestone MAX antifreeze + coolant is GUARANTEED to provide MAXIMUM ENGINE PROTECTION in all Vehicle Makes, Models & Years. It delivers the widest range of temperature protection, industry leading protection from engine damaging rust & corrosion and the longest lasting protection in the industry. Trust Prestone for maximum, year-round engine protection. Volume: 1 gallon.
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Prestone – Prestone Antifreeze and Coolant: 50/50 Ready-to-Use, Universal Platinum, 1 Gallon, AF2550 (Part No.AF2550)

Prestone Antifreeze and Coolant: 50/50 Ready-to-Use, Universal Platinum, 1 Gallon, AF2550

from

$19.99
Prestone Platinum antifreeze+coolant is Prestone’s best universal antifreeze and coolant product. Guaranteed to work with all vehicles; all makes, models, years and fluid colors. 15+ years, 350,000 miles of protection; the fluid is Guaranteed for the life of your vehicle. This advanced product delivers Extreme Protection against both freezing temperatures (-50 deg.) and overheating/boiling over of the engine (+268 deg.). Prestone Platinum utilizes industry leading protection from engine damaging rust, corrosion, buildup and scale. While ordinary antifreeze coolant only focuses on the basic corrosion coverage, Prestone Platinum goes farther, adding our most advanced cooling system protection, allowing the system to run optimally, like when it was new. Internal buildup and corrosion damage can cause engine part failure or clogging, leading to expensive repairs and inconveniences. Prestone Platinum helps you avoid costly repairs and vehicles in the shop. This extended life coolant is Guaranteed to work with all new engines and engine technology, while also being backwards compatible, improving protection in all older engines. Prestone Platinum antifreeze+coolant – Year Round Protection. Volume: 1 gallon.
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Prestone – Prestone MAX Antifreeze + Coolant: All Vehicles, 56/44 Ready-to-Use, 1 Gallon, AF2850 (Part No.AF2850)

Prestone MAX Antifreeze + Coolant: All Vehicles, 56/44 Ready-to-Use, 1 Gallon, AF2850

from

$18.99
All Antifreeze + Coolants are not the same. Prestone MAX antifreeze + coolant is GUARANTEED to provide MAXIMUM ENGINE PROTECTION in all Vehicle Makes, Models & Years. It delivers the widest range of temperature protection, industry leading protection from engine damaging rust & corrosion and the longest lasting protection in the industry. Trust Prestone for maximum, year-round engine protection. Volume: 1 gallon.
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ARGOS – ARGOS Dex-Cool Orange Full Strength Antifreeze, 1 Gallon, AR501 (Part No.AR501)

ARGOS Dex-Cool Orange Full Strength Antifreeze, 1 Gallon, AR501

from

$17.99
ARGOS Orange Concentrate is formulated for cars and light duty trucks that use Orange extended life coolant. ARGOS Orange Concentrate meets or exceeds ASTM D3306 and D4985 standards for corrosion protection, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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ARGOS – ARGOS Extended Life Yellow Full Strength Antifreeze, 1 Gallon, AR301 (Part No.AR301)

ARGOS Extended Life Yellow Full Strength Antifreeze, 1 Gallon, AR301

from

$15.49
ARGOS Extended Life AMAM Concentrate is compatible with ANY antifreeze/coolant in ANY vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. ARGOS Concentrate meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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ARGOS – ARGOS Dex-Cool Orange 50/50 Pre-Diluted Antifreeze, 1 Gallon, AR601 (Part No.AR601)

ARGOS Dex-Cool Orange 50/50 Pre-Diluted Antifreeze, 1 Gallon, AR601

from

$14.99
ARGOS Orange 50/50 is formulated for cars and light duty trucks that use Orange extended life coolant. Top-off your cooling system with ARGOS Orange 50/50, which is a blend of 50% antifreeze and 50% demineralized water. ARGOS Orange 50/50 meets or exceeds ASTM D3306 and D4985 standards for corrosion protection, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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ARGOS – ARGOS Universal Yellow 50/50 Pre-Diluted Antifreeze, 1 Gallon, AR401 (Part No.AR401)

ARGOS Universal Yellow 50/50 Pre-Diluted Antifreeze, 1 Gallon, AR401

from

$12.49
ARGOS Extended Life AMAM 50/50 is compatible with ANY antifreeze/coolant in ANY vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with Prime Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. ARGOS 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection. Volume: 1 gallon.
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Top Picks for 2001 GMC Sierra 2500 HD Sealants

Upgrade GMC Sierra 2500 HDs with top-quality Sealants parts, including 7 OEM and aftermarket selections for your 2001 model.

Permatex – Permatex Sensor-Safe, High-Torque RTV Silicone Gasket Maker, 82194 (Part No.82194)

Permatex Sensor-Safe, High-Torque RTV Silicone Gasket Maker, 82194

from

$12.49
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.
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Permatex – Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195 (Part No.82195)

Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195

from

$29.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.
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Permatex – Permatex Sensor-Safe, High Torque RTV Silicone Gasket Maker, 22074 (Part No.22074)

Permatex Sensor-Safe, High Torque RTV Silicone Gasket Maker, 22074

from

$6.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.
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Permatex – Permatex The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ, 25238 (Part No.25238)

Permatex The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ, 25238

from

$21.99
“Permatex’s The Right Stuff 1 Minute Series offers the fastest return to service in just 1 minute! This leak-proof, elastomeric “”Formed-in-place”” material is more reliable and longer lasting than pre-cut gaskets. It is blowout resistant and protects against leaks and seepage caused by vibration and thermal expansion. The Right Stuff 1 Minute Grey is specified for high torque and high vibration applications and is formulated to meet or exceed performance standards for long-term sealability, durability and handling.”
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Permatex – Permatex Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ, 22071 (Part No.22071)

Permatex Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ, 22071

from

$8.49
Permatex Water Pump & Thermostat RTV Silicone Gasket Maker is a noncorrosive, sensor-safe RTV silicone gasket material formulated for water pumps and thermostat housings. Permatex Water Pump & Thermostat has the highest water-glycol resistance available in an RTV silicone.
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Permatex – Permatex The Right Stuff: Grey, 90 Minute Gasket Maker, 3 oz., 34328 (Part No.34328)

Permatex The Right Stuff: Grey, 90 Minute Gasket Maker, 3 oz., 34328

from

$18.99
“Permatex’s The Right Stuff 90 Minute Series offers the fastest return to service in a in just 90 minute! This leak-proof, elastomeric “”Formed-in-place”” material is more reliable and longer lasting than pre-cut gaskets. It is blowout resistant and protects against leaks and seepage caused by vibration and thermal expansion. The Right Stuff 90 Minute Grey is specified for high torque and high vibration applications and is formulated to meet or exceed performance standards for long-term sealability, durability and handling.”
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Permatex – Permatex Ultra Grey RTV Gasket Maker, OEM Specified, 9.5 oz., 85084 (Part No.85084)

Permatex Ultra Grey RTV Gasket Maker, OEM Specified, 9.5 oz., 85084

from

$42.99
Ultra Grey® Maximum Torque Gasket Maker
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In-Demand Transmission Fluids for 2001 GMC Sierra 2500 HDs

Select from 14 premium Transmission Fluids parts for your 2001 GMC Sierra 2500 HD, with prices ranging from $11.49 to $241.49.

Mobil 1 – Mobil 1 Synthetic Gear Lubricant LS 75W-90, 1 Quart, 26101 (Part No.26101)

Mobil 1 Synthetic Gear Lubricant LS 75W-90, 1 Quart, 26101

from

$21.99
Mobil 1 Synthetic Gear Lubricant LS 75W-90 is a supreme, multi-purpose automotive gear lubricant that helps to provide exceptional thermal stability and resistance to high temperature oxidation, extending gear life due to minimal deposits. Helps to deliver outstanding protection against low speed/high torque wear with the capability to handle severe driving conditions while delivering smooth efficient performance. Mobil 1 Synthetic Gear Lubricant LS provides exceptional shear stability, corrosion protection, and enhanced frictional properties. Compared to conventional hypoid gear lubricants, Mobil 1 LS 75W-90 performs exceptionally over a wide range of temperatures to reduce wear at start up. Mobil 1 gear lube helps to minimize leakage and reduce contamination while providing good resistance to foaming to maintain film strength for reliable lubrication. Meets or exceeds the requirements of the following industry specifications: API GL-5. Volume: 1 quart.
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Valvoline – Valvoline MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart, VV324 (Part No.VV324)

Valvoline MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart, VV324

from

$12.49
Choosing an automatic transmission fluid just got easier. Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, is suitable for use in 95% of ATF vehicles in operation with US registered light duty applications. And now, it’s also recommended for most belt and chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear and tear, and maximize performance – all for much longer than conventional fluids. It has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Whether your vehicle has a CVT or traditional automatic, Valvoline MaxLife Multi-Vehicle ATF is suitable for a broad range of transmissions including Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW and Audi vehicles. For the many miles ahead, trust your transmission with Valvoline, the No. 1 automatic transmission fluid brand. Volume: 1 quart.
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Valvoline – Valvoline Premium Blue 15W-40 Conventional Diesel Engine Oil, Endorsed by Cummins, 1 Gallon, 773780 (Part No.773780)

Valvoline Premium Blue 15W-40 Conventional Diesel Engine Oil, Endorsed by Cummins, 1 Gallon, 773780

from

$26.99
When the going gets tough, the tough get Valvoline Premium Blue. This premium heavy duty engine oil features proprietary One Solution GEN2 Technology designed to protect hardworking diesel, gasoline and natural gas engines in both on-highway and off-highway applications. Our patented, formula is engineered to outperform: resisting oxidation, deposits, corrosion and wear better than industry standards. No wonder it’s The Only One exclusively endorsed and recommended by Cummins for both on road and off highway applications. It’s specially formulated for faster and safer cold starts and has enhanced thermal properties for hot weather operations to help ensure year-round performance. Plus, extended drain intervals reduce oil changes so your engine can work longer between downtime. Volume: 1 gallon.
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Mobil 1 – Mobil 1 Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart, 25201 (Part No.25201)

Mobil 1 Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart, 25201

from

$12.99
Mobil 1 Synthetic ATF is a multi-vehicle, fully synthetic automatic transmission fluid that helps to improve overall transmission durability and cleanliness. Has exceptional thermal and oxidation stability and long-term frictional properties that help to improve and extend transmission efficiency, smooth shifting performance, and fuel economy. Mobil 1 ATF provides excellent low-temperature fluidity to promote reliable lubrication at temperatures down to -51C, and exceptional shear stability to help supports viscosity retention under the most severe heavy-duty, high-temperature operating conditions. Compatible with mineral ATF fluids and all common seal materials to help provide excellent leakage control and reduce concern in top-off emergencies. Meets or exceeds the requirements of JASO 1-A and Ford MERCON V. For more information, visit us at Mobil.US. Volume: 1 quart.
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Idemitsu – Idemitsu Type TLS Automatic Transmission Fluid, 1 Quart, 10106-042K (Part No.10106-042K)

Idemitsu Type TLS Automatic Transmission Fluid, 1 Quart, 10106-042K

from

$11.79
Formulated to meet the specific requirements of Toyota, Lexus, and scion vehicles equipped with conventional (non-CVT) transmissions that require the use of ATF T-IV. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF T-IV is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. Idemitsu is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. Idemitsu application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made. Volume: 1 quart.
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FRAM – FRAM Full Synthetic Dexron VI Automatic Transmission Fluid, 1 Gallon, F426-1G (Part No.F426-1G)

FRAM Full Synthetic Dexron VI Automatic Transmission Fluid, 1 Gallon, F426-1G

from

$32.99
FRAM DEXRON-VI FULL SYNTHETIC ATF represents the latest technology in full synthetic automatic transmission fluids. This product is designed for the newest generation of highly efficient transmissions now being installed in most vehicles, and is DEXRON-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel efficient choice for older models as well, such as those currently using DEXRON-III. FRAM DEXRON-VI FULL SYNTHETIC ATF is recommended for use in all GM DEXRON applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations. Volume: 1 gallon.
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FRAM – FRAM Full Synthetic Dexron VI Automatic Transmission Fluid, 1 Quart, F426 (Part No.F426)

FRAM Full Synthetic Dexron VI Automatic Transmission Fluid, 1 Quart, F426

from

$11.99
FRAM DEXRON-VI FULL SYNTHETIC ATF represents the latest technology in full synthetic automatic transmission fluids. This product is designed for the newest generation of highly efficient transmissions now being installed in most vehicles, and is DEXRON-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel efficient choice for older models as well, such as those currently using DEXRON-III. FRAM DEXRON-VI FULL SYNTHETIC ATF is recommended for use in all GM DEXRON applications and in transmissions applications calling for Toyota WS, Nissan  Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations. Volume: 1 quart.
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FRAM – Fram Full Synthetic Global Multi-Vehicle Automatic Transmission Fluid, 1 Quart, F470 (Part No.F470)

Fram Full Synthetic Global Multi-Vehicle Automatic Transmission Fluid, 1 Quart, F470

from

$11.49
FRAM Global ATF is formulated to meet the fluid needs of a broad range of automatic transmissions. Using advanced additive technology and base fluids, it is suitable for service fill of many transmissions manufactured by North American, Asian, and European OEMs. FRAM Global ATF provides oxidation and thermal stability, friction control, load-carrying ability, corrosion and wear protection. It helps protect against the formation of sludge, varnish and foam. FRAM Global ATF has exceptional low temperature flow properties and enhanced protection against viscosity breakdown at high temperatures. It also has exceptional oxidation and thermal stability, resulting in maximum service life. Volume: 1 quart.
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Pentosin – PENTOSIN ATF 6 1L, 1058106 (Part No.1058106)

PENTOSIN ATF 6 1L, 1058106

from

$41.49
PENTOSIN ATF 6 1L, 1058106. TRANSMISSION FLUID>TRANSMISSION FLUID>DEX/MERC/MULTI VEHICLE>DEX/MERC/MULTI VEHICLE from Pentosin
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Valvoline – Valvoline 5W-30 Full Synthetic Motor Oil, Superior Temperature Performance, 5 Gallon, 881629 (Part No.881629)

Valvoline 5W-30 Full Synthetic Motor Oil, Superior Temperature Performance, 5 Gallon, 881629

from

$241.49
Valvoline Full Synthetic Motor Oil delivers superior engine protection by fighting the three major causes of engine stress: heat, deposits and wear. When you want to keep your engine running its best, choose the ultimate protection found in Valvoline Full Synthetic Motor Oil. Valvoline Full Synthetic Motor Oil meets the GM(1) dexos1 Gen2 and API SN PLUS specifications, helping protect gasoline direct injected engines from low-speed pre-ignition. Volume: 5 gallons.
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ARGOS – ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 6 Gallon Box, AR426-6GLBNB (Part No.AR426-6GLBNB)

ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 6 Gallon Box, AR426-6GLBNB

from

$231.99
ARGOS DEXRON-VI Full Synthetic ATF represents the latest technology in full synthetic automatic transmission fluids. This product is designed for the newest generation of highly efficient transmissions now being installed in most vehicles, and is DEXRON-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel efficient choice for older models as well, such as those currently using DEXRON-III. ARGOS DEXRON-VI Full Synthetic ATF is recommended for use in all GM DEXRON applications and in transmissions applications calling for Toyota WS, Nissan Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations. Volume: 6 gallons.
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ARGOS – ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon, AR426-1G (Part No.AR426-1G)

ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Gallon, AR426-1G

from

$40.99
ARGOS DEXRON-VI Full Synthetic ATF represents the latest technology in full synthetic automatic transmission fluids. This product is designed for the newest generation of highly efficient transmissions now being installed in most vehicles, and is DEXRON-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel efficient choice for older models as well, such as those currently using DEXRON-III. ARGOS DEXRON-VI Full Synthetic ATF is recommended for use in all GM DEXRON applications and in transmissions applications calling for Toyota WS, Nissan Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations. Volume: 1 gallon.
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Castrol – Castrol Transmax ATF/CVT Universal Automatic Transmission Fluid, 1 Gallon, 15E0C8 (Part No.15E0C8)

Castrol Transmax ATF/CVT Universal Automatic Transmission Fluid, 1 Gallon, 15E0C8

from

$28.99
Castrol Transmax ATF/CVT Universal is a technologically advanced full-synthetic formulation designed to deliver excellent performance in most of the traditional stepped automatic transmissions and Continuously Variable Transmissions currently in use. It is also suitable for use in hybrids. Volume: 1 gallon.
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ARGOS – ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart, AR426 (Part No.AR426)

ARGOS Full Synthetic Dexron VI Automatic Transmission Fluid: 1 Quart, AR426

from

$14.99
ARGOS DEXRON-VI Full Synthetic ATF represents the latest technology in full synthetic automatic transmission fluids. This product is designed for the newest generation of highly efficient transmissions now being installed in most vehicles, and is DEXRON-VI licensed by GM and meets JASO 1A performance requirements. It is a fuel efficient choice for older models as well, such as those currently using DEXRON-III. ARGOS DEXRON-VI Full Synthetic ATF is recommended for use in all GM DEXRON applications and in transmissions applications calling for Toyota WS, Nissan Matic J and Matic S, Ford part numbers XT-10-QLV and XT-6-QSP, Honda Z-1 and DW 1, and Hyundai SP-VI. Check owner’s manual for specific recommendations. Volume: 1 quart.
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Most Sold 2001 GMC Sierra 2500 HD Engine Additives

Explore our best-selling GMC parts for the 2001 Sierra 2500 HD among 2 OEM and aftermarket options starting from $487.99.

Yukon Gear – "Yukon Gear Grizzly Locker For GM & Chrysler 11.5"" With 30 Spline Axles, 28013" (Part No.28013)

"Yukon Gear Grizzly Locker For GM & Chrysler 11.5"" With 30 Spline Axles, 28013"

from

$1749.99
The Yukon Grizzly Locker is the ultimate in locking differentials for street, off-road, & drag racing. Grizzly Lockers provide 100% power to both tires, while still allowing for disengagement while negotiating turns. The Yukon Grizzly locker is a mechanical locking differential. It features a forged case and 8620 internals for maximum strength. It’s patented design reduces common locker failures. All units assembled in the USA! All Grizzly Lockers are backed by the best warranty in the business! Yukon covers the replacement unit and covers any collaterally damaged parts and associated labor, up to $2,000!
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Powertrax – Powertrax Differential Lock Assembly, 1950-LR (Part No.1950-LR)

Powertrax Differential Lock Assembly, 1950-LR

from

$487.99
For vehicles that are driven daily, the Power Trax No-Slip Traction System is the latest design in quiet traction-adding differential technology. It combines the automatic street-friendly smooth operation of a limited-slip differential with the traction performance of a locking differential. The Power Trax No-Slip locker easily installs in to your differential carrier using basic tools and without affecting your ring and pinion settings. Power Trax Grip-Lok, Lock-Right Lockers and No-Slip Traction Systems automatically provide 100% traction on-demand, under the toughest circumstances. The Power Trax Grip-Pro and Grip-LS performance limited slips offer smooth dependable torque transfer and traction for the best of both worlds.
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Top-Rated Fluids and Chemicals Brands For Your 2001 GMC Sierra 2500 HD

Shop for the best-rated brands offering Fluids and Chemicals and other products for your 2001 GMC Sierra 2500 HDs. Below you’ll find some of our best rated Fluids and Chemicals from Prestone, Permatex, and Certified A/C Pro, and more. Fluids and Chemicals from these brands that fit a 2001 Sierra 2500 HD start at just $6.99 and are rated as high as 4.8 stars. OEM and aftermarket Fluids and Chemicals don’t get more top quality, durable, and affordable than from the brands below.

Popular Prestone 2001 GMC Sierra 2500 HD Fluids and Chemicals

When it comes to maintaining or upgrading your 2001 GMC Sierra 2500 HD, using quality Fluids and Chemicals is essential to ensure durability and a perfect fit. Prestone ticks all of those boxes. We offer a wide selection of Prestone Fluids and Chemicals, specifically designed for the 2001 GMC Sierra 2500 HD. With over 3 Prestone brand Fluids and Chemicals in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $14.99, with an average price of just $19.66. Plus, with over 1,141 customer reviews and an average rating of 4.8 stars, you can trust that our Prestone Fluids and Chemicals will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Prestone DOT 3 Brake Fluid, 32 oz., AS401
from $14.99
(201)
Prestone DOT 3 Brake Fluid, 32 oz., AS401
“?”

Popular Permatex 2001 GMC Sierra 2500 HD Fluids and Chemicals

Permatex auto parts is one of the highest quality Fluids and Chemical brands in the market. Any 2001 GMC Sierra 2500 HD owner should feel confident when installing genuine Permatex parts in their vehicle. To ensure the best fit and performance for your 2001 Sierra 2500 HD, Advance Auto Parts carries a full inventory of 3 Permatex Fluids and Chemicals. Plus you will be keeping your GMC in peak condition while saving money because prices on these Permatex Fluids and Chemicals range from $6.99 to $29.99, plus, with more than 111 customer reviews and an impressive 4.7 stars average rating, you can be confident the Fram Fluids and Chemicals below will deliver on both quality and value.
Permatex Sensor-Safe, High Torque RTV Silicone Gasket Maker, 22074
from $6.99
(9)
Permatex Sensor-Safe, High Torque RTV Silicone Gasket Maker, 22074
“Did exactly what I needed it to do”
Permatex Sensor-Safe, High-Torque RTV Silicone Gasket Maker, 82194
from $12.49
(95)
Permatex Sensor-Safe, High-Torque RTV Silicone Gasket Maker, 82194
“Had to use another product on a gasket that leaked. Had to redo everything, reset the timing on my old Ford. Should have made the trip back to Advance”
Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195
from $29.99
(7)
Permatex High-Torque, High-Vibration RTV Silicone Gasket Maker, 13 oz., 82195
“it worked great,thank you marv and your crew.”

FAQs for 2001 GMC Sierra 2500 HD Fluids and Chemicals

Which Fluids and Chemicals are best-sellers for 2001 GMC Sierra 2500 HDs?

What’s the price range for 2001 GMC Sierra 2500 HD Fluids and Chemicals?

Fluids and Chemical prices for the 2001 GMC Sierra 2500 HD start at $1.95 and go up to $1,749.99 for the most premium parts.

What’s the average price of a Fluids and Chemical for a 2001 GMC Sierra 2500 HD?

The average price for Fluids and Chemicals for the 2001 GMC Sierra 2500 HD is $60.70. Keep in mind the variety of part types within our Fluids and Chemical category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Fluids and Chemicals for other GMC Sierra 2500 HD model years?

Yes, we currently carry Fluids and Chemicals for 24 model years of GMC Sierra 2500 HDs between 2002 and 2026. Fluids and Chemicals are bought most frequently for the following model years: 2023, 2022, 2024, 2021, 2020, 2019, 2018, 2017, and 2016.

What are the cheapest Fluids and Chemicals for my 2001 GMC Sierra 2500 HD?

What types of Fluids and Chemicals do you sell for my 2001 GMC Sierra 2500 HD?

Can I get help with 2001 GMC Sierra 2500 HD Fluids and Chemical orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about GMC Fluids and Chemicals and more.

What is your return policy for GMC Sierra 2500 HD Fluids and Chemicals?

Advance Auto Parts keeps returns simple. For new GMC Sierra 2500 HD Fluids and Chemicals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.