Lexus RX350 Engine Cooling Parts

Your One-Stop Shop For Trusted Lexus RX350 Engine Cooling Parts

If you’re in search of Lexus RX350 Engine Cooling Parts aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 59 Engine Cooling Parts from top brands with prices ranging from $1.24 to $569.99.

Beyond great prices, we stock trusted brands manufacturing all types of Engine Cooling Parts for your Lexus RX350. Of the 25 OEM and aftermarket parts brands we carry, some of the most popular are Permatex, Carquest Premium, and Felpro.

And don’t forget to read customer reviews across all Engine Cooling Parts categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Engine Cooling Parts have to cost top dollar, and we prove it. Browse our top Lexus RX350 Engine Cooling Parts below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Lexus RX350 Engine Cooling Parts

MTC – Water Pipe O-Ring (Part No.G2026263440MTC)

Water Pipe O-Ring

from

$3.51
Water Pipe O-Ring

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3130)

Engine Water Pump: New, Gasket/Seals Included

from

$134.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
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Dorman – Coolant Housing/Water Outlet: With Housing, 50 Degree Neck Angle (Part No.902-5932)

Coolant Housing/Water Outlet: With Housing, 50 Degree Neck Angle

from

$38.49
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
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Motorad UltraStats – Thermostat: 180 Degrees (Part No.5281-180)

Thermostat: 180 Degrees

from

$21.79
This premium upgraded thermostat is everything you were looking for. UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resistance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components. This is the perfect upgrade to help insure your cooling system is working exactly as you need and expect it to for longevity.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
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Felpro – Engine Coolant Thermostat Seal (Part No.35445)

Engine Coolant Thermostat Seal

from

$5.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
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Dorman – Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees (Part No.902-5216)

Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees

from

$162.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
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Permatex – Sensor-Safe, High Torque RTV Silicone Gasket Maker (Part No.22074)

Sensor-Safe, High Torque RTV Silicone Gasket Maker

from

$6.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)

Engine Coolant Temperature Sensor

from

$82.99
DENSO’s engine coolant temperatures sensors are manufactured to the stricktest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.

Product Features:
  • OE technology adapted for the aftermarket
  • Reduces emissions, increased performance
  • Delivers the highest reliability and detection accuracyá
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Carquest Premium – Reservoir Cap (Part No.T127)

Reservoir Cap

from

$9.79
Reservoir Cap

Felpro – WATER PUMP MOUNTING GASKET SET (Part No.ES 73114)

WATER PUMP MOUNTING GASKET SET

from

$53.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Victor Reinz – Engine Coolant Thermostat Housing Gasket (Part No.71-15397-00)

Engine Coolant Thermostat Housing Gasket

from

$4.79
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
  • Application specific design provides an exceptional fit.
  • Validated for fit, form, and function.
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KAI – Radiator (Part No.RAD13019)

Radiator

from

$219.99
New Platinum Pro Radiator, 3.5 Liter V6 Engine With Automatic Transmission

Product Features:
  • 3.5 Liter V6 Engine With Automatic Transmission, Made Of Plastic and Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Stant – THERMOSTAT SEAL (Part No.27286)

THERMOSTAT SEAL

from

$1.49
THERMOSTAT SEAL

Dorman – Radiator Mount Bushing (Part No.926-278)

Radiator Mount Bushing

from

$9.89
This radiator mount bushing is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this radiator mount bushing matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this bushing is a reliable replacement for an original part that has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
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Elring – SEAL RING – COPPER (Part No.4M20011240ELR)

SEAL RING - COPPER

from

$1.24
SEAL RING – COPPER

Carquest Premium – Radiator Cap Tester Adapter (Part No.12021)

Radiator Cap Tester Adapter

from

$17.79
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
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KAI – Radiator Support Tie Bar (Part No.LX1225153)

Radiator Support Tie Bar

from

$88.99
New Standard Replacement Radiator Support Upper Tie Bar

Product Features:
  • Made Of Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Dorman – Radiator Filler Neck (Part No.G1011719777DOR)

Radiator Filler Neck

from

$53.34
Re-engineered to address common failure points in the original equipment, Dorman’s Engine Coolant Filler Neck has improved durability and resistance. It withstands the extreme changes in temperature that frequently cause housing to become brittle, crack and leak. This is more than a replacement; it’s an upgrade. Maintain the steady flow of coolant and lessen the chances of overheating.

Product Features:
  • Direct replacement for a proper fit every time
  • Quality tested to ensure a trouble-free installation and conformance to product standards
  • High-quality plastic or metal construction
  • Includes all hardware necessary for a complete repair (where applicable)
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Felpro – Engine Water Pump Installation Kit (Part No.ES 73200)

Engine Water Pump Installation Kit

from

$4.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Felpro – Engine Water Pump Gasket (Part No.35807)

Engine Water Pump Gasket

from

$24.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Flex A Lite – Trimline Straight Blade Electric Fan (Part No.116)

Trimline Straight Blade Electric Fan

from

$119.99
Trimline Straight Blade Electric Fan

Santech – Aux. Fan Control Uni (Part No.G5007755207SII)

Aux. Fan Control Uni

from

$179.68
Aux. Fan Control Uni

Permatex – Sensor-Safe, High-Torque RTV Silicone Gasket Maker (Part No.82194)

Sensor-Safe, High-Torque RTV Silicone Gasket Maker

from

$11.49
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
See More

Sankei Switches – Sankei Switches Radiator Cap (Part No.G101045813SAK)

Sankei Switches Radiator Cap

from

$10.06
The Sankei Switches radiator cap range has been developed to operate within original equipment manufacturer’s specifications. A faulty radiator cap can cause your car to boil-over at a lower temperature. Test or replace the coolant cap when servicing the cooling system.

Product Features:
  • Meets Original Equipment specifications.
  • Made from premium materials.
  • Designed to function on open cooling systems and overflow reservoir type systems.
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Felpro – WATER OUTLET GASKET (Part No.35767)

WATER OUTLET GASKET

from

$2.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Engine Cooling Parts Brands You Can Trust For Your Lexus RX350

25 trusted brands of Engine Cooling Parts line our shelves, ready to help keep your Lexus RX350 running smooth. Below are some of the most popular brands and their top Engine Cooling Parts offerings:

Popular Beck/Arnley Engine Cooling Parts

Beck/Arnley products for the Lexus RX350 span several categories. Some of the highest-rated Beck/Arnley Engine Cooling Parts that will fit your Lexus RX350 are:
Thermostat Gasket
from $5.49
(25)
Thermostat Gasket
Thermostat and Water Outlet Gaskets

Top Lexus RX350 Engine Cooling Parts from Permatex

Your Lexus RX350 will be purring again thanks to Permatex brand Engine Cooling Parts available for online order or in-store pick up. Popular Permatex parts include:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets
Sensor-Safe, High Torque RTV Silicone Gasket Maker
from $6.99
(9)
Sensor-Safe, High Torque RTV Silicone Gasket Maker
Engine Water Pump Inlet Pipe Gaskets

Most Purchased Lexus RX350 Engine Cooling Parts from Permatex

When you buy the most frequently purchased Permatex brand Engine Cooling Parts, you can be confident it will be the right part for your Lexus RX350. Here are the Permatex Engine Cooling Parts Advanced Auto customers buy the most:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Engine Water Pump: New, Gasket/Seals Included
from $134.99
(23)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps
Radiator Cap: 16 PSI
from $14.99
(137)
Radiator Cap: 16 PSI
Radiator Caps

FAQs for Lexus RX350 Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the Lexus RX350?

Out of 59 Engine Cooling Parts for the Lexus RX350, the most popular in our inventory are:
Radiator Cap: 16 PSI
from $14.99
(137)
Radiator Cap: 16 PSI
Radiator Caps
Standard Thermostat: 180 Degrees
from $17.79
(75)
Standard Thermostat: 180 Degrees
Thermostats
Engine Coolant Thermostat Seal
from $5.49
(76)
Engine Coolant Thermostat Seal
Engine Coolant Water Inlet Seals

What are the top-rated Lexus RX350 Engine Cooling Parts?

Top-rated Engine Cooling Parts for your Lexus RX350 based on customer reviews/ratings are:
Standard Thermostat: 170 Degrees
from $17.29
(33)
Standard Thermostat: 170 Degrees
“Return it”
Engine Water Pump: New, Gasket/Seals Included
from $134.99
(23)
Engine Water Pump: New, Gasket/Seals Included
“My van started getting hot and the water was leaking out of the side of the block and it scared me and I thought I really messed up my van. Thank good”
Thermostat
from $8.79
(9)
Thermostat
“Install with jiggle valve on top to allow air to purge from cooling system.”