GMC Sierra 2500 HD Spark Plugs

Your One-Stop Shop For Trusted GMC Sierra 2500 HD Spark Plugs

If you’re in search of GMC Sierra 2500 HD Spark Plugs aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 67 Spark Plugs from top brands with prices ranging from $2.99 to $31.99.

Beyond great prices, we stock trusted brands manufacturing all types of Spark Plugs for your GMC Sierra 2500 HD. Of the 9 OEM and aftermarket parts brands we carry, some of the most popular are NGK, ACDelco, and Autolite.

And don’t forget to read customer reviews across all Spark Plugs categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Spark Plugs have to cost top dollar, and we prove it. Browse our top GMC Sierra 2500 HD Spark Plugs below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential GMC Sierra 2500 HD Spark Plugs

Autolite – Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life (Part No.APP6043)

Double Platinum Spark Plug: Platinum Firing, Superior Durability, Longer Life

from

$6.49
With over 100 years of engineering expertise and more than 11 billion plugs sold, Autolite delivers exceptional quality. Designed and engineered in the USA, these spark plugs feature platinum-to-platinum firing, virtually eliminating gap erosion and reducing misfires. The OE design and full-platinum tips on both the center and side electrodes optimize engine performance for a longer life and improved fuel economy. The platinum ball welding process ensures a consistent point of contact for enhanced adhesion, making these spark plugs a reliable choice for superior durability.

Product Features:
  • Works to optimize engine performance for a longer life and improved fuel economy
  • OE design
  • Full-platinum tips; platinum on both the center and side electrodes to promote reduced gap wear
  • Platinum ball welding process provides a consistent point of contact for enhanced adhesion
  • Engineered in the USA: Designed and engineered in the USA, leveraging over 100 years of Autolite’s engineering expertise and quality assurance.
  • Proven Quality: With over 11 billion spark plugs sold, Autolite delivers exceptional quality and reliability, making it a trusted choice for automotive enthusiasts and professionals.
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NGK – OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, IZTR5B11 (Part No.1465)

OE Series Laser Iridium Spark Plug: Fine Wire Tip Design, IZTR5B11

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$15.79
NGK Laser Iridium spark plugs offer the best combination of performance and longevity. Engineered specifically for OE applications, Laser Iridium spark plugs are tested to the highest standards to ensure quality and durability. Iridium tipped center electrode provides durability six times harder than platinum. NGKs high grade pure alumina ceramic and 98 percent pure copper core prevents the spark plug from overheating while providing reliable starts. Most Laser Iridium spark plugs feature a platinum pad on the ground electrode for even wear in distributorless ignition systems.

Product Features:
  • ACTUAL OE or EQUIVALENT DESIGN: OEM quality construction fine wire iridium alloy center electrode provides consistent performance
  • IRIDIUM ALLOY CENTER ELECTRODE: Iridium’s density (6x that of platinum) and extremely high melting point is perfect for modern high efficiency engines
  • PLATINUM TIP GROUND ELECTRODE: Unless OE specified, platinum protection at the ground electrode provides excellent ignitability and service life
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Best for vehicles with OE fine wire iridium alloy plugs
  • Superior Durability: The iridium-tipped center electrode is six times harder than platinum, ensuring long-lasting performance and reliability.
  • OE Application Specific: Engineered specifically for Original Equipment (OE) applications, ensuring a perfect fit and optimal performance.
  • Fine Wire Tip Design: The fine wire tip design of the IZTR5B11 model enhances ignition efficiency and performance.
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Autolite – Platinum Spark Plug: Fires Cleaner, Easier Starts, Quicker Acceleration (Part No.AP5245)

Platinum Spark Plug: Fires Cleaner, Easier Starts, Quicker Acceleration

from

$4.79
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, Autolite Platinum spark plugs provide a center wire platinum firing tip which provides reduced gap erosion, fewer misfires, better performance and increased durability. Consider upgrading to Autolite Double Platinum or Iridium XP spark plugs for increased performance.

Product Features:
  • High nickel alloy side electrode maintains precise gap
  • Full platinum tip assures virtually no gap erosion for long life
  • Necked-down center electrode fires quicker, cleaner with less voltage for easier starts, quicker acceleration and improved fuel economy (as compared to standard plugs)
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E3 – DiamondFIRE Automotive Spark Plug: More Power, Saves Gas (Part No.E3.74)

DiamondFIRE Automotive Spark Plug: More Power, Saves Gas

from

$8.49
The Spark Plugs are the product of years of fundamental research in the combustion field. The unique patented electrode configuration of these new The spark plugs increases the amount of combustion pressure created during each power stroke of an engine, which results in a marked increase in power output, fuel economy, and reduced emissions in all gasoline engines. E3.74 is a 14mm, 1.000 reach plug with a taper seat. It fits a wide variety of late model applications, especially Ford applications. The automotive plugs have three legs securing the Diamond FIRE electrode to the shell. This allows for excellent heat transfer, and helps to create more turbulence in the cylinder. The patented Diamond FIRE side wire is proven to increase power, reduce fuel consumption and improve hydrocarbon emissions in long-term use.

Product Features:
  • E3’s Diamond Fire edge to edge ground electrode provides maximum performance with increased efficiency and a faster more complete burn
  • Smoother Acceleration & Idle – The faster flame initiated by the The spark plug results in a more complete burn of the ingested fuel charge. More pressure is created against the piston more fuel is put to work
  • Energy – Power output improved up to 6% on average in the typical operating ranges. Results will vary.
  • Efficiency – The “diamond shaped” side wire electrode projects the combustion spark in a way that more quickly ignites the air/fuel mixture, thereby creating a significantly faster and larger flame kernel. The result is that more fuel is put to work durin
  • E3’s patented Diamond Fire Technology provides a cleaner burning combustion, which translates into fuel savings and reduced engine carbon deposits
  • The Spark Plugs are pre-gapped at the factory and cannot be adjusted.
  • Enhanced Heat Transfer: Three legs securing the Diamond FIRE electrode to the shell ensure excellent heat transfer and create more turbulence in the cylinder.
  • Wide Compatibility: The E3.74 spark plug is a 14mm, 1.000 reach plug with a taper seat, fitting a wide variety of late model applications, especially Ford vehicles.
  • Eco-Friendly Performance: Proven to reduce fuel consumption and improve hydrocarbon emissions, contributing to a cleaner environment.
  • Long-Term Efficiency: The Diamond FIRE side wire is designed for long-term use, maintaining increased power and reduced fuel consumption over time.
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NGK – Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX (Part No.90220)

Ruthenium HX High Ignitability Spark Plug: DFE Tip Design, LTR5AHX

from

$14.99
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug; Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY DOUBLE FINE ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with opposed fine wire platinum ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PLATINUM PIN TYPE GROUND ELECTRODE: Provides more complete fuel burn, quicker throttle response, smoother idle and better cold starts
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE DFE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Specialized OEM Tip Designs: Features patented DFE and PSPE tip designs for superior ignitability.
  • Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.
  • Advanced OE Technology: Created from advanced Original Equipment technology for modern vehicles.
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ACDelco – RAPIDFIRE Premium Platinum Tip Copper Core Spark Plug: Reduces Misfires & Enhances Durability (Part No.14)

RAPIDFIRE Premium Platinum Tip Copper Core Spark Plug: Reduces Misfires & Enhances Durability

from

$7.99
ACDelco Gold (Professional) RAPIDFIRE Spark Plugs are a high quality alternative to Original Equipment (OE) parts. These RAPIDFIRE Single Platinum Performance Spark Plugs are designed for everyday use and are a high quality replacement for many vehicles on the road today. These premium aftermarket spark plugs have high-quality suppressors that help prevent misfiring, an improved plug to boot seal, and a pure copper core for greater durability. These premium aftermarket replacement spark plugs are manufactured to meet your expectations for fit, form, and function. ACDelco Gold (Professional) parts are manufactured to meet your expectations for fit, form, and function, making them a smart choice for General Motors vehicles, as well as most makes and models, including special applications. These high-quality parts are backed by General Motors. Some ACDelco Gold parts may have formerly appeared as ACDelco Professional.

Product Features:
  • Solid state suppressor, with two-piece glass and brass seal, can help reduce radio frequency interference, regulates spark energy for long electrode life, and helps protect against high combustion pressures
  • Pure copper core provides great heat transfer and helps maximize plug durability
  • Platinum on center electrode enables superior spark characteristics and can reduce voltage requirements of the ignition system
  • Ribless insulator helps optimize plug to boot seal
  • Some ACDelco Gold parts may have formerly appeared as ACDelco Professional
  • Premium aftermarket replacement part
  • Manufactured to meet specifications for fit, form, and function for General Motors vehicles as well as most makes and models
  • High-Quality Suppressors: ACDelco Gold RAPIDFIRE Spark Plugs feature high-quality suppressors that help prevent misfiring, ensuring reliable performance for everyday use.
  • Improved Plug to Boot Seal: Designed with an improved plug to boot seal, these spark plugs provide a secure fit, enhancing overall engine performance and longevity.
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ACDelco – Iridium Spark Plug: Original Equipment Replacement (Part No.41-162)

Iridium Spark Plug: Original Equipment Replacement

from

$11.99
ACDelco GM Original Equipment Iridium Spark Plugs are designed, engineered, and tested to rigorous standards, and are backed by General Motors. They are our latest in spark plug technology and an exact replacement for your vehicle’s original components. Iridium composition provides a high melting point and great strength, and provides excellent wear resistance and durability. ACDelco GM Original Equipment parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional.

Product Features:
  • Iridium is the latest in spark plug technology and is an exact replacement for vehicles’ original components
  • Iridium composition provides a high melting point and great strength, helps to provide excellent wear resistance and durability
  • Iridium offers excellent engine idle stability, reliable cold starting, quick acceleration and smooth performance
  • Three Piece Fired in Suppressor seal meters spark energy for long electrode life, helps prevent combustion leakage and helps block radio frequencies that can affect vehicle electronics
  • Iridium plugs are laser-welded which provides precision welds, reduces excess debris and wear rate, thus increasing durability
  • Some ACDelco GM Original Equipment parts may have formerly appeared as GM Genuine Parts (OE) or ACDelco Professional
  • ACDelco GM Original Equipment parts are designed, engineered and tested to rigorous standards, and are backed by General Motors.
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
  • Resistor Type: Equipped with a resistor to help reduce radio frequency interference, ensuring smooth engine performance.
  • Tapered Seat Type: Features a tapered seat type for a secure fit and reliable performance in your vehicle.
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NGK – Iridium IX Spark Plug: Single Iridium Fine Wire, TR5IX (Part No.7397)

Iridium IX Spark Plug: Single Iridium Fine Wire, TR5IX

from

$11.99
NGK Iridium IX spark plugs are specifically designed for the performance enthusiast. Iridium IX provides outstanding acceleration, high fuel efficiency and durability. NGK Iridium IX plugs offer extreme ignitability and exceptional anti-fouling. Tapered cut ground electrode provides improved starting, idling and throttle response. The Iridium fine wire center electrode’s durability is six times harder than platinum. Iridium alloy’s extremely high melting point is perfect for today’s engines. For even greater performance consider upgrading to an NGK Ruthenium HX plug.

Product Features:
  • SINGLE IRIDIUM TIP: Fine wire 0.6 millimeter iridium tip center electrode ensures high durability and a consistently stable spark
  • IRIDIUM ALLOY CENTER ELECTRODE: Iridium’s density (6x that of platinum) and extremely high melting point is perfect for modern high efficiency engines
  • TAPERED CUT GROUND ELECTRODE: Reduced quenching design produces outstanding ignitability, improved acceleration, fuel efficiency and durability
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modified or high performance applications, or as an upgrade to OE nickel alloy spark plugs
  • Outstanding Acceleration and High Fuel Efficiency: NGK Iridium IX spark plugs are engineered to deliver exceptional acceleration and improved fuel efficiency, making them ideal for performance enthusiasts.
  • Extreme Ignitability and Anti-Fouling: These spark plugs offer extreme ignitability and exceptional resistance to fouling, ensuring reliable performance in various driving conditions.
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DENSO – Iridium TT Spark Plug: Ultimate Endurance and Power, 0.4mm Iridium Tip, last 100K+ Miles, IT16TT (Part No.4713)

Iridium TT Spark Plug: Ultimate Endurance and Power, 0.4mm Iridium Tip, last 100K+ Miles, IT16TT

from

$10.99
Durability of an OE style plug combined with Power & Torque of high performance.

Product Features:
  • 0.4mm Iridium Center Electrode: World’s Smallest Diameter that maximizes firing potential
  • 0.7mm Needle Tip Ground Electrode: Promotes higher spark energy and less heat quenching
  • DENSO Patented Optimized Iridium-Rhodium Alloy Formula: Highest concentration of Iridium vs. competitors for greater durability
  • DENSO Patented 360 degree laser welding process: Ensuring exceptional quality bond and structural strength with the Iridium Center Electrode
  • Durability of an OE style plug combined with Power & Torque of high performance.
  • Withstands temperatures greater than 4000┬░ Fahrenheit
  • Iridium TT
  • Advanced Twin-Tip Technology: Combines a Fine Wire Iridium Center Electrode with a Needle Tip Platinum Ground Electrode for superior ignition and efficiency.
  • Enhanced Fuel Economy and Lower Emissions: Designed to provide better fuel economy and reduced emissions, allowing you to drive around the Earth over 4 times.
  • Original Equipment Specification: Developed from the Super Ignition Plug (SIP) design, ensuring reliable and consistent performance.
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Motorcraft – Spark Plug (AGSF52CA) (Part No.SP-442-A)

Spark Plug (AGSF52CA)

from

$3.99
Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles engineered to meet strict Ford engineering standards to provide original equipment performance and reliability. Delivering performance, reliability and confidence, Motorcraft spark plugs are available for a broad range of applications, including domestic and import cars and trucks of all makes and sizes.

Product Features:
  • Motorcraft spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption and optimize emissions.
  • Backed by Motorcraft’s Service Parts Warranty
  • Exact fit for Ford, Lincoln and Mercury vehicles
  • Resistant to oxidation and arc erosion.
  • Multi-rib insulator protects against misfire.
  • Service intervals of up to 100,000 miles.
  • Motorcraft Spark Plugs are designed with high quality materials to provide reliable performance for almost any application.
  • Motorcraft Spark Plugs are what was in the vehicle when it was manufactured
  • Motorcraft ignition components help prevent false check engine lights.
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Autolite – Platinum Spark Plug: Fires Cleaner, Easier Starts, Quicker Acceleration (Part No.AP5243)

Platinum Spark Plug: Fires Cleaner, Easier Starts, Quicker Acceleration

from

$4.79
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, Autolite Platinum spark plugs provide a center wire platinum firing tip which provides reduced gap erosion, fewer misfires, better performance and increased durability. Consider upgrading to Autolite Double Platinum or Iridium XP spark plugs for increased performance.

Product Features:
  • High nickel alloy side electrode maintains precise gap
  • Full platinum tip assures virtually no gap erosion for long life
  • Necked-down center electrode fires quicker, cleaner with less voltage for easier starts, quicker acceleration and improved fuel economy (as compared to standard plugs)
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Motorcraft – SPARK PLUG (Part No.SP-442-X)

SPARK PLUG

from

$6.99
SPARK PLUG

ACDelco – Spark Plug Wire (Part No.357D)

Spark Plug Wire

from

$31.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Specific FitSpark Plug Wire (Part No.349V)

Specific FitSpark Plug Wire

from

$19.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Spark Plug Wire (Part No.356F)

Spark Plug Wire

from

$28.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Original Equipment Ignition Wire (Part No.F1030575906ACD)

Original Equipment Ignition Wire

from

$22.14
Built to match the original equipment in length and fit, ACDelco OES Ignition Wires offer a performance advantage over many aftermarket products.

Product Features:
  • ACDelco ignition wires are designed to be like Original in critical areas such as cable length and diameter, terminal design and insulator position
  • Have broad coverage available for most vehicles on the road today from 1980 to present
  • Provide a high degree of Radio Frequency Interference (RFI) suppression
  • Are designed to offer fit, form and function for optimum performance
  • Kevlar reinforced fiberglass core in select sets for increased strength
  • Core sheathed in radio-static absorbent material for increased RFI suppression
  • Wire-wound, stainless steel alloy conductor for maximum spark delivery and RFI suppression on most applications
  • A layer of conductive heat-resistant latex for added durability
  • Insulating rubber-based compound inner jacket helps minimize voltage drop and enhance durability
  • Thick silicone outer jacket for excellent heat resistance
  • Limited lifetime warranty*
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ACDelco – Spark Plug Wire (Part No.350R)

Spark Plug Wire

from

$24.99
ACDelco GM Original Equipment Spark Plug Wires consist of a single wire, encased in an insulating material, connectors, and insulating boots, and are GM-recommended replacements for your vehicle’s original components. The wires transfer high voltage pulses between the voltage source, the distributor, and the spark plug. These original equipment wires have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Durable to help transfer high voltage pulses without damage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Spark Plugs Brands You Can Trust For Your GMC Sierra 2500 HD

9 trusted brands of Spark Plugs line our shelves, ready to help keep your GMC Sierra 2500 HD running smooth. Below are some of the most popular brands and their top Spark Plugs offerings:

Popular Motorcraft Spark Plugs

Motorcraft products for the GMC Sierra 2500 HD span several categories. Some of the highest-rated Motorcraft Spark Plugs that will fit your GMC Sierra 2500 HD are:
Spark Plug (AGSF52C)
from $3.29
(1)
Spark Plug (AGSF52C)
Spark Plugs

Most Purchased GMC Sierra 2500 HD Spark Plugs from ACDelco

When you buy the most frequently purchased ACDelco brand Spark Plugs, you can be confident it will be the right part for your GMC Sierra 2500 HD. Here are the ACDelco Spark Plugs Advanced Auto customers buy the most:
Iridium Spark Plug: Original Equipment Replacement
from $11.99
This product is not rated
Iridium Spark Plug: Original Equipment Replacement
Spark Plugs

FAQs for GMC Sierra 2500 HD Spark Plugs

What are the most purchased Spark Plugs for the GMC Sierra 2500 HD?

Out of 67 Spark Plugs for the GMC Sierra 2500 HD, the most popular in our inventory are:
Iridium Spark Plug: Original Equipment Replacement
from $11.99
This product is not rated
Iridium Spark Plug: Original Equipment Replacement
Spark Plugs

What are the top-rated GMC Sierra 2500 HD Spark Plugs?

Top-rated Spark Plugs for your GMC Sierra 2500 HD based on customer reviews/ratings are:
DiamondFIRE Automotive Spark Plug: More Power, Saves Gas
from $8.49
(176)
DiamondFIRE Automotive Spark Plug: More Power, Saves Gas
“Great spark plug!!!!”
Iridium IX Spark Plug: Single Iridium Fine Wire, TR55IX
from $11.99
(103)
Iridium IX Spark Plug: Single Iridium Fine Wire, TR55IX
“2000 GT Mustang had bad misfire These plugs made the car run like new again.OE plugs just would not last.”