GMC Sierra 2500 HD Differential Pinion Seals

Your GMC Sierra 2500 HD will be happy to know that the search for the right Differential Pinion Seals you’ve been looking for is over! Advance Auto Parts has 16 different Differential Pinion Seals for your vehicle, ready for shipping or in-store pick up. The best part is, our GMC Sierra 2500 HD Differential Pinion Seals start from as little as $9.99.

When it comes to your GMC Sierra 2500 HD, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Differential Pinion Seals brands so you can shop with complete confidence. Some of our top Differential Pinion Seals brands are National and Yukon Gear. We’re sure you will get the right product to keep that Sierra 2500 HD running for a long time.

We even have reviews of our OEM and aftermarket Differential Pinion Seals products to help you buy with confidence. Hear from other customers via the 3,289 reviews on parts for your GMC Sierra 2500 HD.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Differential Pinion Seals for your Sierra 2500 HD, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 25 GMC Differential Pinion Seals

National – Multi Purpose Seal (Part No.710474)

Multi Purpose Seal

from

$19.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Motive Gear – Differential Pinion Seal (Part No.2043)

Differential Pinion Seal

from

$3.49
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

National – Multi Purpose Seal (Part No.3896)

Multi Purpose Seal

from

$17.49
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710281)

Multi Purpose Seal

from

$19.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Differential Pinion Seal (Part No.S-8622)

Differential Pinion Seal

from

$7.79
Product Features:
  • Brand may vary by location
See More

Driveworks – Oil Seal (Part No.S-5778)

Oil Seal

from

$10.49
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710536)

Multi Purpose Seal

from

$34.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710506)

Multi Purpose Seal

from

$16.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710508)

Multi Purpose Seal

from

$44.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.100712V)

Multi Purpose Seal

from

$30.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: springless; single-lip
  • Temperature range: -100°F to 450°F; -73°C to 232°C
  • Resistant to hydrocarbon/oxygenate blends and provides superior performance
  • Provides excellent dry running capabilities, low coefficient of friction and excellent resistance to chemicals
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.6818)

Multi Purpose Seal

from

$21.29
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Motive Gear – Differential Pinion Seal (Part No.8610)

Differential Pinion Seal

from

$3.99
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

Motive Gear – Differential Pinion Seal (Part No.5778)

Differential Pinion Seal

from

$9.49
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

Yukon Gear – 10.5" & 11.5" GM & Dodge Pinion Seal (Part No.30281)

10.5" & 11.5" GM & Dodge Pinion Seal

from

$25.99
10.5″ & 11.5″ GM & Dodge pinion seal.Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits Chrysler 10.5″ and 11.5″
See More

National – Multi Purpose Seal (Part No.100727)

Multi Purpose Seal

from

$26.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: springless; single-lip
  • Temperature range: -100°F to 450°F; -73°C to 232°C
  • Resistant to hydrocarbon/oxygenate blends and provides superior performance
  • Provides excellent dry running capabilities, low coefficient of friction and excellent resistance to chemicals
  • Delivers quality and reliable performance for every type of repair
See More

Yukon Gear – Dana 25 / 27 / 30 / 36 / 44 / 50 Pinion Seal Replacement (Part No.30128)

Dana 25 / 27 / 30 / 36 / 44 / 50 Pinion Seal Replacement

from

$17.99
Replacement pinion seal for Dana 25, Dana 27, Dana 30, D36, Dana 44, & Dana 50 .Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits Dana Spicer 25, 27, 30, 40 and 50
See More

Motive Gear – Differential Pinion Seal (Part No.9316)

Differential Pinion Seal

from

$16.49
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

Yukon Gear – 8.5" GM 4WD Front Pinion Seal (Part No.30195)

8.5" GM 4WD Front Pinion Seal

from

$13.99
8.5″ GM 4WD front pinion seal.Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits GM 8.5″ front
See More

Yukon Gear – Pinion Seal For GM 8.5", 8.2", Buick, Oldsmobile, And Pontiac (Part No.30017)

Pinion Seal For GM 8.5", 8.2", Buick, Oldsmobile, And Pontiac

from

$9.99
Pinion seal for GM 8.5″, 8.2″, Buick, Oldsmobile, and Pontiac.Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits GM 8.5″ rear, 8.2″ and 8.2″ in Buick, Oldsmobile and Pontiac
See More

Driveworks – Oil Seal (Part No.S-9316)

Oil Seal

from

$3.99
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

Motive Gear – Differential Pinion Seal (Part No.26064029)

Differential Pinion Seal

from

$38.99
Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both o
See More

Yukon Gear – Pinion Seal, New Design Yoke With Triple Lip For GM 8.5" And 8.6" (Part No.30163)

Pinion Seal, New Design Yoke With Triple Lip For GM 8.5" And 8.6"

from

$35.99
Pinion seal, new design yoke with triple lip for GM 8.5″ and 8.6″.Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits GM 8.6″
See More

National – Multi Purpose Seal (Part No.5778V)

Multi Purpose Seal

from

$69.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Design type: spring loaded; multi-lip
  • Temperature range: -100°F to 450°F; -73°C to 232°C
  • Resistant to hydrocarbon/oxygenate blends and provides superior performance
  • Provides excellent dry running capabilities, low coefficient of friction and excellent resistance to chemicals
  • Delivers quality and reliable performance for every type of repair
See More

Motive Gear – Differential Pinion Seal (Part No.6808N)

Differential Pinion Seal

from

$24.99
All Motive Gear products are engineered for their specific application and manufactured in state of the art facilities. All of our products undergo rigid quality control processes to insure proper fit, performance and longevity. Motive Gear products can be found in the winners circle at NHRA, IHRA, NMRA, NMCA, SODA, SCORE, BITD, Ultra-4 and NASCAR events because we offer unmatched selection and quality demanded by racers and their crew chiefs – the same quality and selection demanded by DIY customers and top mechanics. With four warehouses strategically located across North America, most Motive Gear orders arrive within 2-4 days. Win with Motive Gear!
See More

Yukon Gear – 7.2" GM 7.5" GM & 8.2" GM Pinion Seal (Part No.30192)

7.2" GM 7.5" GM & 8.2" GM Pinion Seal

from

$9.99
7.2″ GM 7.5″ GM & 8.2″ GM pinion seal.Yukon Mighty seal.

Product Features:
  • Pinion seal
  • Fits GM 7.2″ IFS, 1999 and down GM 7.5″ and 7.625″ and GM 8.2″
  • 2.660″ O.D.
See More

FAQs for GMC Sierra 2500 HD Differential Pinion Seals

What are the most popular Differential Pinion Seals for the GMC Sierra 2500 HD?

With 7 brands you can trust, our most popular Differential Pinion Seals for the GMC Sierra 2500 HD are:
Multi Purpose Seal
from $44.99
(5)
Multi Purpose Seal
Differential Pinion Seals
Multi Purpose Seal
from $34.99
(8)
Multi Purpose Seal
Differential Pinion Seals
10.5" & 11.5" GM & Dodge Pinion Seal
from $25.99
This product is not rated
10.5" & 11.5" GM & Dodge Pinion Seal
Differential Pinion Seals