Ford F-450 Super Duty Coolant/Antifreeze

Your One-Stop Shop For Trusted Ford F-450 Super Duty Coolant/Antifreeze

If you’re in search of Ford F-450 Super Duty Coolant/Antifreeze aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 23 Coolant/Antifreeze from top brands with prices ranging from $10.99 to $25.49.

Beyond great prices, we stock trusted brands manufacturing all types of Coolant/Antifreeze for your Ford F-450 Super Duty. Of the 6 OEM and aftermarket parts brands we carry, some of the most popular are Prestone, ZEREX, and Peak.

And don’t forget to read customer reviews across all Coolant/Antifreeze categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Coolant/Antifreeze have to cost top dollar, and we prove it. Browse our top Ford F-450 Super Duty Coolant/Antifreeze below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Ford F-450 Super Duty Coolant/Antifreeze

FRAM – Antifreeze & Coolant: 50/50 Ready To Use, OE North American Gold, 1 Gallon (Part No.F301)

Antifreeze & Coolant: 50/50 Ready To Use, OE North American Gold, 1 Gallon

from

$13.99
Fram Extended Life AMAM Concentrate is compatible with ANY antifreeze/coolant in ANY vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. FRAM Concentrate meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up & boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT & IAT
  • 5 Yr., 150,000 mile Extended life formula.
  • Meets or exceeds ASTM D3306 & D4985 for corrosion protection.
  • Concentrated formula. Must mix with high quality (distilled/deionized) water to the desired ratio. Can be used for top-off, complete drain and refill or flush and refill of the cooling system.
See More

Peak – 10X Antifreeze + Coolant Concentrate for All Vehicles – 1 Gallon (Part No.PKP0B3)

10X Antifreeze + Coolant Concentrate for All Vehicles - 1 Gallon

from

$19.79
PEAK® Antifreeze + Coolant Concentrate is specially engineered to deliver guaranteed superior lifetime protection. Its advanced universal formula contains a proprietary blend of 10X the scale-fighting inhibitors coupled with robust organic additives to fight against the damaging effects of scale deposits and corrosion. PEAK Antifreeze + Coolant is free of 2-EHA, silicate, nitrite, borate, and amines, ensuring maximum cooling system performance for 10+ years/300,000+ miles. It is compatible for use with any color or type of antifreeze/coolant in the system.

Product Features:
  • Specially formulated to deliver Superior Lifetime Protection against damaging scale and corrosion
  • Contains 10X the scale-fighting inhibitors to ensure maximum cooling system performance
  • Provides more than 2X the warranty coverage for 10+ years/300,000+ miles of service
  • Universal formula is compatible with any color or type of antifreeze/coolant
  • Meets the performance requirements of ASTM D3306 and D4985
See More

Prestone – Antifreeze and Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon (Part No.AF888)

Antifreeze and Coolant: Concentrate, Dex-Cool Compatible, Protects Against Corrosion, 1 Gallon

from

$21.49
Prestone DEX-COOL (concentrate) antifreeze+coolant is specially designed to work with these specific vehicles: All GM® vehicles 1995 & newer (GM approved), most Ford® vehicles 2011 – 2018 and most Chysler® vehicles 2013 & newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, they also protect the engine from rust & corrosion. This fluid is designed to last 5yrs / 150,000 miles.

Product Features:
  • Specially formulated to work with vehicles using orange colored fluid; HOAT. All GM 1995 & newer; Most Ford 2011-2018; Most Chrysler 2013 & newer
  • 5 Yr., 150,000 mile Extended life formula
  • Includes the Prestone protection package that protects against rust and corrosion of all cooling system metals, including aluminum.
  • Concentrate formula. Must mix with distilled to the desired mix ratio of EG & water. Can be used for top-off, complete drain and refill or flush and refill of the cooling system.
See More

Prestone – Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon (Part No.AF2100)

Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon

from

$14.99
Prestone All Vehicles antifreeze+coolant (ready to use) is truly designed to work with all vehicles; all makes, models, years & fluid colors. It is designed to work with all new engines while also being backwards compatible improving protection in all older engines. The patented Cor-Guard technology (the best innovation in the category in decades) instantly protects parts from corrosion, buildup, pitting, scaling, rust and other damage. These fluids are specially designed to not only manage the engine temp and protect from freezing up (like competitors), but they also potect the engine from damage. Internal damage can cause engine part failure, leading to expensive repairs and serious inconveniences. Avoid costly repairs and vehicles in the shop with Prestone All Vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, offically patented by Prestone.

Product Features:
  • Formulated to work with All Vehicles. Works with all fluid colors; All OAT, POAT, HOAT & IAT.
  • Longer Engine Life Guarantee – 10 Yr., 300,000 mile Extended life formula.
  • Includes patented Prestone CorGuard technology, the best advancement in cooling system parts protection that protects against rust and corrosion of all cooling system metals, including aluminum. Protection for 300,000 miles.
  • Ready to Use formula (prediluted to a 50% Eg & 50% distilled water mix). Perfect for small volume top-off or complete drain and refill of the cooling system
See More

Motorcraft – Gold 50/50 Prediluted Antifreeze / Coolant, 1 Gallon (Part No.VC-7DIL-B)

Gold 50/50 Prediluted Antifreeze / Coolant, 1 Gallon

from

$25.49
The only parts recommended by Ford Motor Company for Ford, Lincoln, and Mercury vehicles. Premium-quality ethylene-glycol based mixes meet the strict standards of Ford engineers for performance and longevity. Provides year-round anti-freeze and anti-boil protection. Assures premium corrosion protection for the engine, water pump and other cooling system components. Motorcraft antifreeze and coolant contains bittering agent; Available in concentrated formula, as well as pre-diluted to eliminate mixing errors and reduce mixing time for your service technicians. Motorcraft offers the only antifreeze and coolants recommended by Ford Motor Company, using non-approved coolants can void the warranty for cooling system repairs.

Product Features:
  • Recommended by Ford Motor Company meeting warranty requirements
  • Yellow-colored, longer-life, ethylene glycol-based antifreeze/coolant for use in gasoline and diesel engines, and electric motors
  • Provides year-round antifreeze, anti-boil and corrosion protection
  • Ready-to-use. No need to add water. The 50/50 mixture of this antifreeze/coolant and treated (purified) water provides freeze protection down to -34 °F (-36.7 °C) and boiling protection up to 265 °F (129 °C)
  • Meets or exceeds the requirements of WSS-M97B51-A1, ASTM D 3306, Chrysler MS-9769, Cummins 14603, and ASTM D 6210
  • Contains a bittering agent
See More

Peak – Original Equipment North American Orange Antifreeze and Coolant: 50/50 Ready To Use, 1 Gallon (Part No.NAOB53)

Original Equipment North American Orange Antifreeze and Coolant: 50/50 Ready To Use, 1 Gallon

from

$19.99
PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES is a line of premium coolants specifically designed to match the technology and color requirements of North American vehicles. Each coolant is formulated with the same corrosion inhibitor technology that protected your vehicle straight from the factory. Color cues on the packaging and a list of covered vehicles on the front label make it easy to identify the right match for your specific vehicle. PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES – ORANGE is an extended life antifreeze/coolant based on proprietary state-of-the-art organic acid technology (OAT). The ethylene glycol-based formula represents a carefully balanced mixture of organic acid corrosion inhibitors for complete protection of modern high-performance North American vehicle engines. It can be mixed with any DEX-COOL approved formulations in newer GM, Opel, Daewoo and Saab vehicles, as well as with antifreeze/coolant in Ford and Chrysler vehicles requiring an orange type product. This product’s orange color distinguishes its unique chemistry and ensures easy selection for North American vehicles requiring this type and color of coolant. PEAK ORIGINAL EQUIPMENT TECHNOLOGY ANTIFREEZE + COOLANT for NORTH AMERICAN VEHICLES – ORANGE is free of silicate, borate, phosphate, nitrite, and amines, and is fully compatible with other extended life coolants. It meets the performance requirements of ASTM D3306 and D4985. When installed as part of a complete flush and coolant fill, PEAK guarantees this coolant will provide service life protection of up to 150,000 miles or 5 years.

Product Features:
  • Matches technology and color requirements of North American OEMs specifying a Green Conventional coolant
  • Protects all cooling system metals, including aluminum, against damaging rust and corrosion
  • Compatible with other conventional green antifreeze + coolant formulations
  • Easy-to-pour bottle with color-coding and vehicle applications listed on the front to simplify selecting the right antifreeze + coolant
  • Available as both concentrate and 50/50 prediluted products to do the job right
  • Testing Requirements: For proper freeze and boil over protection, use a traditional refractometer or hydrometer to measure the percentage of ethylene glycol by volume.
See More

Prestone – Antifreeze and Coolant: 50/50 Ready To Use, Universal Platinum, 1 Gallon (Part No.AF2550)

Antifreeze and Coolant: 50/50 Ready To Use, Universal Platinum, 1 Gallon

from

$19.99
Prestone® Platinum antifreeze+coolant is Prestone’s best universal antifreeze & coolant product. GUARANTEED to work with all vehicles; all makes, models, years & fluid colors. 15+ years, 350,000 miles of protection; the fluid is guaranteed for the life of your vehicle. This advanced product delivers Extreme Protection against both freezing temperatures (-50 Deg. F) and overheating / boiling over of the engine (+268 Deg. F). Prestone Platinum utilizes industry leading protection from engine damaging rust, corrosion, buildup & scale. While ordinary antifreeze coolant only focuses on the basic corrosion coverage, Prestone Platinum goes farther, adding our most advanced cooling sytem protection, allowing the system to run optimally, like when it was new. Internal buildup & corrosion damage can cause engine part failure or clogging, leading to expensive repairs and inconveniences. Prestone Platinum helps you avoid costly repairs and vehicles in the shop. This extended life coolant is guaranteed to work with all new engines and engine technology, while also being backwards compatible, improving protection in all older engines. Prestone Platinum antifreeze+coolant – Year Round Protection.

Product Features:
  • Guaranteed to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT & IAT; G05®, G11®, G12®, G12++®, G13®, G30®, G40®, & GG40®. For all engines & engine sizes, new and older engines.
  • 15+ Yr., 350,000 mile Extended life formula. The fluid is guaranteed for the life of your vehicle
  • Includes our most advanced Prestone Cor-Guard® technology, unmatched cooling system parts protection that protects against engine damage; rust, corrosion, scale, build-up and clogging. Protection for 15+yrs / 350,000 miles.
  • Ready to Use formula – Prediluted 56/54. Perfect for small volume top-off or complete drain and refill of the cooling system
See More

Peak – Fleet Charge Heavy Duty Antifreeze and Coolant: Concentrate, Protection Against Corrosion, 1 Gallon (Part No.FCA0B3)

Fleet Charge Heavy Duty Antifreeze and Coolant: Concentrate, Protection Against Corrosion, 1 Gallon

from

$23.99
PEAK FLEET CHARGE SCA Pre-charged 50/50 Prediluted Antifreeze + Coolant is a Fully Formulated, ethylene glycol-based coolant, Pre-charged with advanced technology Supplemental Coolant Additives (SCAs). Because it is SCA Pre-charged, FLEET CHARGE SCA Pre-charged Antifreeze + Coolant requires no SCAs at initial fill and ensures proper chemistry at every top-off. FLEET CHARGE SCA Pre-charged Antifreeze + Coolant uses a low silicate and phosphate-free formulation.

Product Features:
  • Works in ALL heavy-duty diesel, gasoline and natural gas engine cooling systems. FLEET CHARGE is a low silicate, low total dissolved solids antifreeze which can be used in all heavy duty applications.
  • Optimum protection against freezing and boil over.
  • Provides corrosion protection of all cooling system metals and components.
  • Incorporates nitrite to provide wet sleeve liner protection against cavitation.
  • Designed to last the life of the engine when maintained with a high quality SCA ?lter system.
  • Eliminates SCA mixing errors at initial ?ll. Phosphate free formula reduces the risk of scale.
  • Testing Requirements: For proper freeze and boil over protection, use a traditional refractometer or hydrometer to measure the percentage of ethylene glycol by volume.
See More

Prestone – Antifreeze and Coolant: 50/50 Ready To Use, Original Equipment North American Orange, 1 Gallon (Part No.AF6700)

Antifreeze and Coolant: 50/50 Ready To Use, Original Equipment North American Orange, 1 Gallon

from

$22.99
Prestone American Vehicles (Orange) antifreeze+coolant is specially designed to work with these specific vehicles: Ford 2002 and newer; Chrysler 2000 and newer; GM 1995 and newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, but they also protect the engine from rust, corrosion, buildup, pitting and engine damage. All of those can cause engine part failure and expensive repairs. Avoid costly repairs and vehicles in the shop with Prestone Asian vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, offically patented by Prestone.

Product Features:
  • Specially formulated to work with vehicles using multiple colors of fluid; OAT, HOAT, G05. Ford 2002 and newer; Chrysler 2000 and newer; GM (Chevrolet, Buick, GMC, Cadillac, Oldmobile, Pontiac, Saturn) 1995 and newer.
  • Superior protection guarantee – 10 Yr., 300,000 mile Extended life formula
  • Includes patented Prestone CorGuard technology, the best advancement in cooling system parts protection that protects against rust and corrosion of all cooling system metals, including aluminum. Protection for 300,000 miles.
  • Ready to Use formula. Perfect for small volume top-off or complete drain and refill of the cooling system.
See More

Prestone – MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon (Part No.AF2800)

MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon

from

$18.99
All Anitfreeze + Coolants are not the same. Prestone® MAX antifreeze + coolant is GUARANTEED to provide MAXIMUM ENGINE PROTECTION in all Vehicle Makes, Models & Years. It delivers the widest range of temperature protection, industry leading protection from engine damaging rust & corrosion and the longest lasting protection in the industry. Trust Prestone for maximum, year-round engine protection.

Product Features:
  • Can top off or replace all antifreeze + coolant colors and formulations in all Vehcile Makes, Models & Years – Guaranteed.
  • Our patented, advance formula provides extreme temperature protection from the worst of winter deep freezes and scorching summer heat.
  • We deliver industry leading protection from engine damaging rust, corrosion & buildup. Prestone MAX completely stops the formation of rust & corrosion for better engine performance and longer engine life.
  • Prestone Max is guaranteed to protect your vehicle for 15+ years and/or 350,000 miles. It¿s the longest fluid life in the industry.
  • Prestone Max is guaranteed to protect your vehicle for 15+ years and/or 350,000 miles. It┐s the longest fluid life in the industry.
  • This is a Concentrated Formula. Must mix with high quality water to the desired ratio.
See More

FRAM – Extended Life AMAM Antifreeze 50/50 Ready-to Use, 1 Gallon (Part No.F401)

Extended Life AMAM Antifreeze 50/50 Ready-to Use, 1 Gallon

from

$10.99
FRAM Extended Life AMAM 50/50 is compatible with ANY antifreeze/coolant in ANY vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with FRAM Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. FRAM 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up & boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT & IAT.
  • 5 Yr., 150,000 mile Extended life formula.
  • Meets or exceeds ASTM D3306 & D4985 for corrosion protection.
  • Ready to Use formula (prediluted to a 50% Eg & 50% distilled water mix). Perfect for small volume top-off or complete drain and refill of the cooling system
See More

ZEREX – G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon (Part No.ZXG051)

G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon

from

$22.99
ZEREX G05® is the automaker approved original chemistry used in newer Ford®, Chrysler® and Mercedes-Benz® automotive and diesel engines. Its Hybrid Organic Acid Technology (HOAT) chemistry combines the best of conventional and organic acid-based chemistry to provide the ultimate protection against rust and corrosion. ZEREX G05 antifreeze/coolant uses the highest quality virgin ethylene glycol for freeze and boil over protection and a hybrid organic acid corrosion inhibitor package to protect your engines from liner pitting and corrosion.

Product Features:
  • Automaker approved technology. Provides protection for 5 years / 150,000 miles in light duty applications and 3 years / 300,000 miles in heavy duty applications
  • Formulated for long life performance
  • Low-silicate, low-pH and phosphate-free formula
  • Helps protect all cooling system metals, including aluminum
See More

Red Line – WATER WETTER (Part No.3E200329365RED)

WATER WETTER

from

$13.40
Specifications: ASTM D2570 and ASTM D1384 Color: Pink Concentrate: Treats 3 to 5 gallons or 13.2 to 15.9 liters. Volume: Case of 12 – 12oz Bottles Redline Water Wetter include a unique agent that lowers temperatures by reducing or eliminating bubbles or vapor barrier that form on hot metal surfaces

Product Features:
  • Unique agent for cooling systems that doubles the wetting ability of water that can reduce temps by 20 degrees F.
  • Rust and corrosion protection allows for use of straight water in racing or reduced antifreeze levels in warm climates
  • Improves heat transfer and reduces cylinder head temperature
  • May allow more spark advance for increase power and efficiency
  • Use one bottle for most passenger cars and light trucks, treats 3 to 5 gallons or 13.2 to 15.9 liters. Vehicles with larger cooling systems should use two bottles. Small cooling systems should use 1oz (3 to 4 capfuls) per quart
  • Compatible with new or used antifreeze (including DEX-COOLTM and long-life versions) to improve the heat transfer of ethylene and propylene glycol systems
  • Satisfies ASTM D2570 and ASTM D1384 corrosion tests for glycol-based antifreezes RED LINE WATERWETTER® COOLANT ADDITIVES
  • Reduces or eliminates bubbles or vapor barrier that form on hot metal surfaces to reduce coolant temperatures by up to 20°
  • Superior heat transfer properties compared to glycol-based antifreeze
  • Compatible with new or used antifreeze (including DEX-COOL and long-life versions) to improve the heat transfer of ethylene and propylene glycol systems
  • Improves heat transfer and reduces cylinder head temperature
  • Designed for use with all modern aluminum, cast iron, copper, brass and bronze cooling systems
  • Cleans and lubricates water pump seals
  • Reduces cavitation and complexes with hard water to reduce scaling
  • Does not lower cooling system below the thermostatically-controlled temperature
See More

Coolant/Antifreeze Brands You Can Trust For Your Ford F-450 Super Duty

6 trusted brands of Coolant/Antifreeze line our shelves, ready to help keep your Ford F-450 Super Duty running smooth. Below are some of the most popular brands and their top Coolant/Antifreeze offerings:

Most Purchased Ford F-450 Super Duty Coolant/Antifreeze from Prestone

When you buy the most frequently purchased Prestone brand Coolant/Antifreeze, you can be confident it will be the right part for your Ford F-450 Super Duty. Here are the Prestone Coolant/Antifreeze Advanced Auto customers buy the most:
Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon
from $14.99
This product is not rated
Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon
Engine Coolant and Antifreeze
Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup And Rust, 1 Gallon
from $17.99
This product is not rated
Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup And Rust, 1 Gallon
Engine Coolant and Antifreeze
Antifreeze and Coolant: 50/50 Ready To Use, Dex-Cool Compatible, 1 Gallon
from $17.99
(417)
Antifreeze and Coolant: 50/50 Ready To Use, Dex-Cool Compatible, 1 Gallon
Engine Coolant and Antifreeze

FAQs for Ford F-450 Super Duty Coolant/Antifreeze

What are the most purchased Coolant/Antifreeze for the Ford F-450 Super Duty?

Out of 23 Coolant/Antifreeze for the Ford F-450 Super Duty, the most popular in our inventory are:
Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon
from $14.99
This product is not rated
Antifreeze and Coolant: 50/50 Ready To Use, Universal, Protects Against Corrosion, 1 Gallon
Engine Coolant and Antifreeze
Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup And Rust, 1 Gallon
from $17.99
This product is not rated
Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup And Rust, 1 Gallon
Engine Coolant and Antifreeze
G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon
from $22.99
(464)
G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon
Engine Coolant and Antifreeze

What are the top-rated Ford F-450 Super Duty Coolant/Antifreeze?

Top-rated Coolant/Antifreeze for your Ford F-450 Super Duty based on customer reviews/ratings are:
G05 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon
from $19.99
(464)
G05 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon
“Perfect for *Dodge Charger”
WATER WETTER
from $13.40
(2)
WATER WETTER
“I have used this product for 20 years in every race car I have worked on. Used in ALMS, Rolex series and World challenge. Ran only distilled water and”