Ford F-250 Pickup Axle Spindle Seals

Your Ford F-250 Pickup will be happy to know that the search for the right Axle Spindle Seals you’ve been looking for is over! Advance Auto Parts has 11 different Axle Spindle Seals for your vehicle, ready for shipping or in-store pick up. The best part is, our Ford F-250 Pickup Axle Spindle Seals start from as little as $2.99.

When it comes to your Ford F-250 Pickup, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Axle Spindle Seals brands so you can shop with complete confidence. Some of our top Axle Spindle Seals brands are National and DriveWorks. We’re sure you will get the right product to keep that F-250 Pickup running for a long time.

We even have reviews of our OEM and aftermarket Axle Spindle Seals products to help you buy with confidence. Hear from other customers via the 746 reviews on parts for your Ford F-250 Pickup.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Axle Spindle Seals for your F-250 Pickup, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 15 Ford Axle Spindle Seals

National – Multi Purpose Seal (Part No.710701)

Multi Purpose Seal

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Oil Seal (Part No.S-722109)

Oil Seal

from

$5.29
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.722109)

Multi Purpose Seal

from

$8.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710455)

Multi Purpose Seal

from

$6.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.722108)

Multi Purpose Seal

from

$11.79
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Oil Seal (Part No.S-722108)

Oil Seal

from

$4.79
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710414)

Multi Purpose Seal

from

$11.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.340835)

Multi Purpose Seal

from

$5.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710413)

Multi Purpose Seal

from

$23.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710453)

Multi Purpose Seal

from

$22.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.472394)

Multi Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Driveworks – Axle Spindle Seal (Part No.S-710414)

Axle Spindle Seal

from

$6.49
Product Features:
  • Brand may vary by location
See More

Driveworks – Oil Seal (Part No.S-416273)

Oil Seal

from

$2.99
Value-priced seal meets all cataloged application requirements.

Product Features:
  • Brand may vary by location
See More

National – Multi Purpose Seal (Part No.710044)

Multi Purpose Seal

from

$3.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

National – Multi Purpose Seal (Part No.710045)

Multi Purpose Seal

from

$9.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

FAQs for Ford F-250 Pickup Axle Spindle Seals

What are the most popular Axle Spindle Seals for the Ford F-250 Pickup?

With 2 brands you can trust, our most popular Axle Spindle Seals for the Ford F-250 Pickup are:
Multi Purpose Seal
from $23.99
(11)
Multi Purpose Seal
Axle Spindle Seals
Oil Seal
from $5.29
(1)
Oil Seal
Axle Spindle Seals
Multi Purpose Seal
from $8.79
(1)
Multi Purpose Seal
Axle Spindle Seals