Ford F-250 HD Drive Shafts and Axles

Your One-Stop Shop For Trusted Ford F-250 HD Drive Shafts and Axles

If you’re in search of Ford F-250 HD Drive Shafts and Axles aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 40 Drive Shafts and Axles from top brands with prices ranging from $3.40 to $1,282.99.

Beyond great prices, we stock trusted brands manufacturing all types of Drive Shafts and Axles for your Ford F-250 HD. Of the 10 OEM and aftermarket parts brands we carry, some of the most popular are Spicer, National, and Dorman.

And don’t forget to read customer reviews across all Drive Shafts and Axles categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Drive Shafts and Axles have to cost top dollar, and we prove it. Browse our top Ford F-250 HD Drive Shafts and Axles below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Ford F-250 HD Drive Shafts and Axles

National – Shaft Repair Sleeve (Part No.99139)

Shaft Repair Sleeve

from

$39.99
National® has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Designed to repair damaged, grooved or worn shafts
  • Durable stainless steel construction for corrosion-free sealing surface that surpasses most original shaft specifications
  • Ideal for a shaft where indications of seal wear, such as tracks or grooves have developed
  • Ultra-thin construction (0.01/0.25mm wall thickness) allows original seal size to be used with minimal additional lip loading
  • Easy to install with removable flange and installation tool
  • Installation tool reduces sleeve distortion and allows for installation without removal from the shaft
See More

National – Multi Purpose Seal (Part No.470672)

Multi Purpose Seal

from

$14.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Dorman – Front Drive Shaft: Greaseable, Adjustable (Part No.938-066)

Front Drive Shaft: Greaseable, Adjustable

from

$631.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Drive Shaft: Greaseable, Adjustable (Part No.976-221)

Rear Drive Shaft: Greaseable, Adjustable

from

$1282.99
Replacing a drive shaft doesn’t have to be complicated. This complete drive shaft assembly is pre-balanced and ready to install with 100% new yokes, tubes, constant velocity (CV) joints and universal joints.

Product Features:
  • Direct replacement – this drive shaft is made to the original equipment dimensions for dependable fit and performance
  • 100% new – this drive shaft is made from all new components so there’s no core charge or return hassle
  • Ready to install – this drive shaft arrives pre-balanced to make installation quick and simple
  • Serviceable construction – non-staked universal joints are designed for future serviceability
See More

Dorman – Rear Axle Differential Vent (Part No.924-263)

Rear Axle Differential Vent

from

$9.99
This axle vent is designed to match the fit and function of the original vent on specified vehicles, and is engineered for durability and reliable performance.

Product Features:
  • Direct replacement – this axle vent is designed to match the fit and function of the original vent on specified vehicles
  • Restores functionality – reliable replacement for an original vent that has failed due to blockage or fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

National – Multi Purpose Bearing (Part No.HB-88107-A)

Multi Purpose Bearing

from

$44.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Controlled heat treating process for lasting performance and extended bearing life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

National – Multi Purpose Bearing (Part No.HB-88508-A)

Multi Purpose Bearing

from

$73.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Controlled heat treating process for lasting performance and extended bearing life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

National – Multi Purpose Seal (Part No.710492)

Multi Purpose Seal

from

$49.99
National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

Product Features:
  • Low swell in hydrocarbon fluids
  • Design type: spring loaded; multi-lip
  • Provides good low temperature capability
  • Temperature range: -40°F to 225°F; -40°C to 107°C
  • Delivers quality and reliable performance for every type of repair
See More

Dorman – Rear Axle O-Ring Kit (Part No.926-163)

Rear Axle O-Ring Kit

from

$16.29
The axle shaft o-ring seals the rear axle to the wheel hub. The symptom of a failed axle shaft o-ring is an axle fluid leak around wheel hub. This is an ideal repair solution to prevent axle fluid leaks from forming around the wheel hub.

Product Features:
  • Aftermarket exclusive replacement part
  • Recommended for replacement when servicing vehicle brakes
  • Direct replacement for original equipment
  • This part has undergone extensive vehicle try-on and durability testing to ensure strength, fitment and longevity
See More

SKF – Driveshaft Support (Part No.K10301069521SKF)

Driveshaft Support

from

$68.67
Driveshaft Support

National – Bearings (Part No.207)

Bearings

from

$32.99
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Controlled heat treating process for lasting performance and extended bearing life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Spicer – Universal Joint (Part No.5-178X)

Universal Joint

from

$42.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.
See More

Spicer – Universal Joint (Part No.5-160X)

Universal Joint

from

$40.99
When you see the Spicer name, you know you are buying the highest quality product available. Spicer universal joints are no exception. Dana manufactures a full line of Spicer universal joints that are engineered to ensure longer life for vehicles.
See More

Dorman – Help – Driveshaft Flange Bolts (Part No.80992)

Driveshaft Flange Bolts

from

$20.29
This drive shaft bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

Product Features:
  • Direct replacement – this engine mount bolt matches the fit and function of the factory part on specified years, makes and models
  • Ideal solution – this drive shaft bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Axle Spindle Nut (Part No.K4030212888DOR)

Axle Spindle Nut

from

$3.40
Dorman’s Spindle Nut is manufactured for high corrosion resistance and a long service life. Depending on the application, it is also available in a kit that includes the nut, washer, and retainer.

Product Features:
  • Direct replacement for a proper fit every time
  • High quality steel construction
  • Conveniently available in many styles and in packs of different quantities
  • Dorman’s Spindle Nuts are constructed to strict engineering quality standards
See More

NTN – Wheel Bearing (Part No.K8000345509NTN)

Wheel Bearing

from

$90.54
Wheel Bearing

National – Bearings (Part No.28580)

Bearings

from

$48.49
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

National – Bearings (Part No.HM88610)

Bearings

from

$15.49
National Oil Seals & Bearings offer a full line of premium oil seals and bearings.

Product Features:
  • Premium bearing design matches OEM specifications
  • Precision manufactured using premium-grade steel for outstanding durability and performance
  • Crowned raceways and rollers to ensure even load distribution for maximum life
  • Industry leading coverage
  • Professional technicians know they can depend on National
See More

Drive Shafts and Axles Brands You Can Trust For Your Ford F-250 HD

10 trusted brands of Drive Shafts and Axles line our shelves, ready to help keep your Ford F-250 HD running smooth. Below are some of the most popular brands and their top Drive Shafts and Axles offerings:

Popular Spicer Drive Shafts and Axles

Spicer products for the Ford F-250 HD span several categories. Some of the highest-rated Spicer Drive Shafts and Axles that will fit your Ford F-250 HD are:
Universal Joint
from $40.99
(10)
Universal Joint
Axle Shaft Universal Joints
Universal Joint
from $51.99
(1)
Universal Joint
Axle Shaft Universal Joints
Universal Joint
from $44.99
(7)
Universal Joint
Axle Shaft Universal Joints

Top Ford F-250 HD Drive Shafts and Axles from National

Your Ford F-250 HD will be purring again thanks to National brand Drive Shafts and Axles available for online order or in-store pick up. Popular National parts include:
Multi Purpose Bearing
from $44.99
(25)
Multi Purpose Bearing
Drive Shaft Center Supports
Multi Purpose Bearing
from $73.99
(17)
Multi Purpose Bearing
Drive Shaft Center Supports
Multi Purpose Seal
from $49.99
(5)
Multi Purpose Seal
Axle Shaft Seals

Most Purchased Ford F-250 HD Drive Shafts and Axles from National

When you buy the most frequently purchased National brand Drive Shafts and Axles, you can be confident it will be the right part for your Ford F-250 HD. Here are the National Drive Shafts and Axles Advanced Auto customers buy the most:
Multi Purpose Bearing
from $73.99
(17)
Multi Purpose Bearing
Drive Shaft Center Supports
Universal Joint
from $40.99
(10)
Universal Joint
Axle Shaft Universal Joints
Universal Joint
from $42.99
(5)
Universal Joint
Axle Shaft Universal Joints

FAQs for Ford F-250 HD Drive Shafts and Axles

What are the most purchased Drive Shafts and Axles for the Ford F-250 HD?

Out of 40 Drive Shafts and Axles for the Ford F-250 HD, the most popular in our inventory are:
Universal Joint
from $42.99
(5)
Universal Joint
Axle Shaft Universal Joints
Driveshaft Flange Bolts
from $20.29
(1)
Driveshaft Flange Bolts
Drive Shaft Support Bolts
Center Support Bearing Motor Mount: Center, 1 Piece
from $22.79
(13)
Center Support Bearing Motor Mount: Center, 1 Piece
Center Support Bearings

What are the top-rated Ford F-250 HD Drive Shafts and Axles?

Top-rated Drive Shafts and Axles for your Ford F-250 HD based on customer reviews/ratings are:
Rear Axle Differential Vent
from $9.99
(6)
Rear Axle Differential Vent
“Does also work on 85 f250 with a dana 70 u”
Ball Bearing
from $19.99
(5)
Ball Bearing
“Easy Installation, Exact Fit”
Drive Shaft Center Support
from $29.49
(4)
Drive Shaft Center Support
“great part excellent service”