Ford E-350 Super Duty Thermostat and Water Outlet Assemblies

Your Ford E-350 Super Duty will be happy to know that the search for the right Thermostat and Water Outlet Assemblies you’ve been looking for is over! Advance Auto Parts has 5 different Thermostat and Water Outlet Assemblies for your vehicle, ready for shipping or in-store pick up. The best part is, our Ford E-350 Super Duty Thermostat and Water Outlet Assemblies start from as little as $28.49.

When it comes to your Ford E-350 Super Duty, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Thermostat and Water Outlet Assemblies brands so you can shop with complete confidence. Some of our top Thermostat and Water Outlet Assemblies brands are Carquest Premium and Motorad. We’re sure you will get the right product to keep that E-350 Super Duty running for a long time.

We even have reviews of our OEM and aftermarket Thermostat and Water Outlet Assemblies products to help you buy with confidence. Hear from other customers via the 153 reviews on parts for your Ford E-350 Super Duty.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Thermostat and Water Outlet Assemblies for your E-350 Super Duty, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 25 Ford Thermostat and Water Outlet Assemblies

Dorman – Thermostat Assembly: Includes Housing and Thermostat Assembly, 180 Degrees (Part No.902-682)

Thermostat Assembly: Includes Housing and Thermostat Assembly, 180 Degrees

from

$48.49
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Housing, 208 Degrees (Part No.902-820)

Thermostat Assembly: Includes Housing, 208 Degrees

from

$156.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Integrated Thermostat Housing: With Seal, 194 Degrees (Part No.736-194)

Integrated Thermostat Housing: With Seal, 194 Degrees

from

$79.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Water Outlet and O-Ring (Part No.902-200)

Thermostat Assembly: Includes Water Outlet and O-Ring

from

$62.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Engine Coolant Thermostat Housing Assembly (Part No.902-903)

Engine Coolant Thermostat Housing Assembly

from

$151.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14899)

Integrated Thermostat Housing: With Seal, 192 Degrees

from

$30.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing, Gasket, Bolts and Clip (Part No.902-210)

Thermostat Assembly: Includes Housing, Gasket, Bolts and Clip

from

$72.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit & durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models.
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Thermostat Assembly: With Sensor, Housings, Thermostat and Seals, 192 Degrees (Part No.TA2210S)

Thermostat Assembly: With Sensor, Housings, Thermostat and Seals, 192 Degrees

from

$94.99
This thermostat assembly is everything you need for a quick and easy replacement for the job. This item is completely assembled and torqued down to the OE specifications, so you don¿t need to worry. This has everything installed/assembled together so there is no need to worry about swapping items or reusing old parts. Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Thermostat Assembly: Includes Housings, Thermostat, Seals, 192 Degrees (Part No.15269)

Thermostat Assembly: Includes Housings, Thermostat, Seals, 192 Degrees

from

$55.99
Carquest Premium Thermostat Assemblies are everything you need for a quick and easy replacement for the job. This item is completely assembled and torqued down to the OE specifications, so you don¿t need to worry. This has everything installed/assembled together so there is no need to worry about swapping items or reusing old parts. Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Seal, 180 Degrees (Part No.48708)

Integrated Thermostat Housing: With Seal, 180 Degrees

from

$21.79
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing, Gasket, Bolts, Sensor, and Clip (Part No.902-860)

Thermostat Assembly: Includes Housing, Gasket, Bolts, Sensor, and Clip

from

$82.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Integrated Thermostat Housing: 192 Degrees (Part No.539-192)

Integrated Thermostat Housing: 192 Degrees

from

$67.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Assembly: With Sensor, Housings, Thermostat and Seals, 192 Degrees (Part No.TA2860S)

Thermostat Assembly: With Sensor, Housings, Thermostat and Seals, 192 Degrees

from

$108.99
This thermostat assembly is everything you need for a quick and easy replacement for the job. This item is completely assembled and torqued down to the OE specifications, so you don¿t need to worry. This has everything installed/assembled together so there is no need to worry about swapping items or reusing old parts. Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Sensor, With Seal, 208 Degrees (Part No.48672)

Integrated Thermostat Housing: With Sensor, With Seal, 208 Degrees

from

$112.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing and Thermostat Assembly, 190 Degrees (Part No.902-810)

Thermostat Assembly: Includes Housing and Thermostat Assembly, 190 Degrees

from

$182.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Thermostat Assembly: With Housings, Thermostat, Sensors and Seals, 192 Degrees (Part No.TA2062S)

Thermostat Assembly: With Housings, Thermostat, Sensors and Seals, 192 Degrees

from

$99.99
This thermostat assembly is everything you need for a quick and easy replacement for the job. This item is completely assembled and torqued down to the OE specifications, so you don¿t need to worry. This has everything installed/assembled together so there is no need to worry about swapping items or reusing old parts. Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees (Part No.4888KT)

Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees

from

$61.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Seal, 195 Degrees (Part No.5617KT)

Thermostat Kit: Includes Housing, Thermostat and Seal, 195 Degrees

from

$28.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Seal, 195 Degrees (Part No.5000KT)

Thermostat Kit: Includes Housing, Thermostat and Seal, 195 Degrees

from

$31.49
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Assembly: With Housings, Thermostat, Sensor and Seals, 192 Degrees (Part No.TA2061S)

Thermostat Assembly: With Housings, Thermostat, Sensor and Seals, 192 Degrees

from

$70.99
This thermostat assembly is everything you need for a quick and easy replacement for the job. This item is completely assembled and torqued down to the OE specifications, so you don¿t need to worry. This has everything installed/assembled together so there is no need to worry about swapping items or reusing old parts. Manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Seal, 180 Degrees (Part No.514-185)

Integrated Thermostat Housing: With Seal, 180 Degrees

from

$43.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees (Part No.4831KT)

Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees

from

$15.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Seal, 195 Degrees (Part No.48689)

Integrated Thermostat Housing: With Seal, 195 Degrees

from

$37.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees (Part No.4884KT)

Thermostat Kit: Includes Housing, Thermostat and Gasket, 192 Degrees

from

$18.79
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Thermostat Kit: Includes Housing, Thermostat and Seal, 192 Degrees (Part No.5190KT)

Thermostat Kit: Includes Housing, Thermostat and Seal, 192 Degrees

from

$43.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

FAQs for Ford E-350 Super Duty Thermostat and Water Outlet Assemblies

What are the most popular Thermostat and Water Outlet Assemblies for the Ford E-350 Super Duty?

With 3 brands you can trust, our most popular Thermostat and Water Outlet Assemblies for the Ford E-350 Super Duty are:
Integrated Thermostat Housing: With Seal, 192 Degrees
from $30.49
(9)
Integrated Thermostat Housing: With Seal, 192 Degrees
Thermostat and Water Outlet Assemblies
Thermostat Kit: Includes Housing, Thermostat and Seal, 192 Degrees
from $43.99
This product is not rated
Thermostat Kit: Includes Housing, Thermostat and Seal, 192 Degrees
Thermostat and Water Outlet Assemblies
Thermostat Kit: Includes Housing, Thermostat and Seal, 194 Degrees
from $32.99
This product is not rated
Thermostat Kit: Includes Housing, Thermostat and Seal, 194 Degrees
Thermostat and Water Outlet Assemblies