Ford E-350 Super Duty Ignition and Tune-Up Products

Please Select your Vehicle to See Exact Fit Parts

Essential Ford E-350 Super Duty Ignition and Tune-Up Products

Carquest Premium – Multi-Purpose Relay (Part No.GPC1001)

Multi-Purpose Relay

from

$66.99
Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
See More

MSD Ignition – Harness; Ford 4.6L Modular to DIS-4 Ignition (Part No.88813)

Harness; Ford 4.6L Modular to DIS-4 Ignition

from

$195.99
Using MSD’s DIS-4 ignition systems on your coil-on-plug Ford has always been a great upgrade, but honestly, the wiring poses quite a challenge. To ease this install, we now offer a wiring harness kit that’ll make the install nearly a direct plug-in. The harness provides a splice-free installation with connectors that plug directly into the factory unit. They even have corresponding wire colors. When used in conjunction with two DIS-4 ignitions and four dual ignition Adapters, PN 89121, your coil-on-plug Ford will receive all the spark it needs plus a two-step rev limit and step retard. And the best part is wiring will only take about an hour.

Product Features:
  • Easily install two DIS-4 Ignitions on late model Ford Engines
  • Easy Connections w/No Splicing Or Cutting Into Factory Wiring
  • Wiring the system will take only an hour
  • Multiple direct plug in connectors
  • Wiring the system will only take and hour
See More

MSD Ignition – MSD DIS-4 Plus; Distributorless 4 Channel (Part No.62152)

MSD DIS-4 Plus; Distributorless 4 Channel

from

$972.99
DIS-4 is capable of firing up to four coil packs or four individual coils. Each control delivers full power capacitive discharge sparks from idle through racing rpm. Below 3,000 rpm there is a series of multiple sparks that last for up to 20 degrees of crankshaft rotation to improve idle, starting and throttle response. The adjustable features of the DIS ignitions have also been upgraded with rotary dials. These provide easier, and more precise adjustments of the overrev limiter and the hole shot rev limit. Also, there is now a step retard that can be wired directly to a nitrous system or switch for activation. For use on 6 or 8 cylinder engines with two, three or four coil packs.

Product Features:
  • Two Step Rev Control
  • Step Retard
  • LED Monitor
  • Features Are Adjustable w/Rotary Switches
See More

NGK – Direct Ignition Coil on Plug Boot: Hi-Temp. Premium Silicone (Part No.59022)

Direct Ignition Coil on Plug Boot: Hi-Temp. Premium Silicone

from

$7.49
Product Features:
  • IMPROVED HIGH TEMPERATURE DESIGN: Solves melting problems for certain very high heat applications
  • OEM MATCHED: Includes all required internal springs and ferrite resistors for superior performance and RFI noise suppression
  • LIMITED WARRANTY: See package for details
See More

Motorcraft – Single Lead Spark Plug Wire (Part No.WR-6170)

Single Lead Spark Plug Wire

from

$49.99
Motorcraft Single Lead Spark Plug Wires must endure a series of punishing tests including a series of demanding test-to-failure endurance and materials durability tests to ensure their long-lasting quality and operation.

Product Features:
  • The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.
  • Motorcraft ignition system components create and control the electrical functions of engine operation in Ford-built vehicles.
  • The ignition includes the Ignition Coil and modules that generate up to 46,000 volts for spark plug firing as well as the crankshaft position monitor and Power Train Control module or PCM.
  • Motorcraft Ignition components are manufactured to exacting Ford OE specifications and quality standards.
  • As with all Motorcraft aftermarket parts, any engineering innovations or product improvements developed since the vehicle’s manufacture are added to these Ignition components, ensuring the most current technology.
See More

Accel – Coil:Ford Mod Eng 3V Ext Boot (Part No.140033E)

Coil:Ford Mod Eng 3V Ext Boot

from

$27.99
ACCEL Super Coils feature advanced bobbin technology, highly specialized silicon magnetic steel cores, optimized windings, proper resistance and engineered turn ratios that deliver a high performance, quality coil. Specialized high temperature epoxy resists shock and vibration, while increasing thermal conductivity. These are direct high performance replacements for OEM coils.

Product Features:
  • Specialized silicone magnetic steel cores are surrounded by precision wrapped windings using advanced bobbin technology which helps maintain the proper resistance and turn ratios necessary to deliver improved performance spark
  • Direct Plug In Replacement Direct OE Fit
  • Direct Plug In Replacement results in a Direct OE Fit
  • OBD ll Safe, so you won’t be throwing codes, just sparks
  • OBD II Compatible Safe
  • Improved Idle Quality
  • Resists Shock And Vibration
  • Resists Corrosion
See More

Carquest Premium – Multi-Use Connector (Part No.ABC2852)

Multi-Use Connector

from

$79.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
See More

Bosch – Knock Sensor (Part No.0261231316)

Knock Sensor

from

$28.99
Bosch OE quality knock sensors for optimum engine protection and fuel consumption reduction up to 9%.

Product Features:
  • Bosch OE quality knock sensors for optimum engine protection
  • Bosch OE quality knock sensors increase torque up to 5%
  • Bosch OE quality knock sensors enable the use of multiple quality fuels with various anti-knock properties
See More

Dorman – Panel Retainer (Part No.963-003D)

Panel Retainer

from

$4.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
See More

Carquest Premium – Multi-Use Connector (Part No.PTC3128)

Multi-Use Connector

from

$122.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
See More

Dorman – Glow Plug Relay Module (Part No.904-282)

Glow Plug Relay Module

from

$181.99
A properly functioning glow plug is essential to cold-weather starts. This direct replacement for the original part restores proper glow plug function and has been validated for specific vehicle years, make and models.

Product Features:
  • Ideal solution – this diesel glow plug controller restores the glow plug power system to original operation
  • Ideal solution – reliable replacement for a controller that has failed due to fatigue
  • Durable construction – made from quality materials to ensure reliable service
  • Trustworthy design – backed by a team of engineers and product designers in the United States
See More

Autolite – Diesel Engine Glow Plug: High Intensity Concentrated Heat, Reliable Starts (Part No.1114)

Diesel Engine Glow Plug: High Intensity Concentrated Heat, Reliable Starts

from

$22.99
Autolite Glow Plugs are engineered to warm the combustion chamber to ensure proper fuel ignition, leading to quicker and more seamless startups.

Product Features:
  • Designed with a nickel-chrome alloy that enables the plug to reach high heat intensity quickly, for reliable cold starts.
  • The sheathed coil heaters provide improved pre-heating and quicker starts.
  • Its precision machined nickel-plated threads with no burring allow for easy installation.
  • For dependability and long-lasting performance, use Autolite glow plugs
  • High Intensity Concentrated Heat- Autolite glow plugs generate intense heat to warm the combustion chamber, ensuring reliable ignition even in cold conditions.
  • Enhanced Cold Start Performance- Specifically engineered to address cold start problems, ensuring your diesel engine starts smoothly in low-temperature environments.
See More

Motorcraft – Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1 (Part No.WR-6128)

Original Equipment Spark Plug Boot: No core (outer material Rubber) Core, Qty of 1

from

$21.99
Motorcraft Ignition Boots are engineered to provide original equipment performance and reliability. All Motorcraft parts undergo rigorous lab and real-world tests in order to meet strict Ford engineering standards. Terminal ends are designed to help ensure they do not separate from the cable under normal service conditions. High dialectic insulation helps maintain and control voltage delivery while reducing radio frequency interference. The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles

Product Features:
  • Backed by Motorcraft’s Service Parts Warranty
  • Designed for long life – key life durability testing (equivalent to 10 years/150,000 miles) is conducted in addition to on-vehicle durability testing.
  • Boots must pass submerged and pressurized leak tests, as well as low temperature cycle tests.
  • Durability tests subject boots to 225,000 performance cycles including temperature extremes from minus 40 degrees F to 275 degrees F.
  • Motorcraft ignition components help prevent false check engine lights.
See More

Carquest Premium – Ignition Switch (Part No.CSC3797)

Ignition Switch

from

$78.99
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The Ignition Switch allows for reliable control of the vehicle’s electrical systems and engine start-up, enhancing convenience and ensuring consistent performance during operation. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
See More

Dorman – Help – Cylinder Head Repair Kit (Part No.42025)

Cylinder Head Repair Kit

from

$68.99
This spark plug thread repair kit is designed to repair stripped spark plug threads in the cylinder heads of specific Ford and Lincoln vehicles, saving you time and money by eliminating the need to remove or replace the entire cylinder head. This convenient, complete kit comes with one boot, one spring, one sleeve and one spark plug.

Product Features:
  • Direct repair – this spark plug thread repair kit is designed to repair spark plug threads that have become stripped on specific Ford and Lincoln vehicles with Triton or Intech engines.
  • Complete solution – this cylinder head repair kit includes everything you need to repair spark plug threads, including one boot, one spring, one sleeve and one spark plug
  • Saves time and money – this kit replaces stripped spark plug threads and eliminates the need to replace the entire cylinder head
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Ignition Coil Connector (Part No.645-570)

Ignition Coil Connector

from

$48.99
This ignition coil connector is designed to match the appearance and function of the original hardware on specified applications. Made of quality materials, it is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this ignition coil connector matches the appearance and function of the factory hardware on specified applications
  • Ideal solution – this connector is a reliable replacement for an original part that is missing or has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Fuel Bowl Seal Kit (Part No.904-498)

Fuel Bowl Seal Kit

from

$37.99
This fuel filter housing seal kit is designed to match the original hardware required to reseal and repair fuel lines on specified vehicles. Made of quality components, this kit is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this fuel filter housing seal kit is designed to match the original hardware required to reseal and repair fuel lines on specified vehicles
  • Ideal solution – this kit is a reliable replacement for original components that are leaking or damaged
  • Durable construction – this kit is made from quality components to ensure reliable performance and a long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Glow Plug Harness (Part No.904-453)

Glow Plug Harness

from

$55.99
This replacement glow plug wiring harness matches the fit and function of the original equipment harness and is made of quality materials for durability and reliable performance.

Product Features:
  • Ideal replacement – this diesel glow plug wiring harness matches the fit and function of the original equipment harness to restore proper operation to the glow plug circuit
  • Durable construction – this glow plug wiring harness is made of quality materials to ensure reliable performance and a long service life
  • Cost-effective solution – offers original equipment performance at competitive price
  • Quality tested – this part has undergone try-on testing to ensure a quality fit
See More

Accel – Accel Ford 3 Vlv Mtr Coil Kit (Part No.140033-8)

Accel Ford 3 Vlv Mtr Coil Kit

from

$334.99
ACCEL Super Coils feature advanced bobbin technology, highly specialized silicon magnetic steel cores, optimized windings, proper resistance and engineered turn ratios that deliver a high performance, quality coil. Specialized high temperature epoxy resists shock and vibration, while increasing thermal conductivity. These are direct high performance replacements for OEM coils.

Product Features:
  • Specialized silicone magnetic steel cores are surrounded by precision wrapped windings using advanced bobbin technology which helps maintain the proper resistance and turn ratios necessary to deliver improved performance spark
  • Advanced Bobbin Technology
  • Direct Plug In Replacement results in a Direct OE Fit
  • OBD ll Safe, so you won’t be throwing codes, just sparks
  • Standard Motor Products SMP Fd-508
  • MSD 8243 82438
  • 8 Pack
See More

Carquest Premium – Spark Plug Boot Set: 8 Boots, Meets or Exceeds OE Specifications (Part No.38-001FMP)

Spark Plug Boot Set: 8 Boots, Meets or Exceeds OE Specifications

from

$53.99
Carquest Premium spark plug boot sets are engineered to restore ignition boot reliability and performance. They are designed to meet or exceed original equipment (O.E.) specifications for fit, form and function. Our spark plug boots offer excellent heat resistance as well as maximum protection against spark loss. Carquest Premium spark plug boot sets are built with a durable silicone compound for resistance to high heat and abrasion, resulting in a longer-lasting ignition repair. Carquest Premium spark plug boot sets include all boots needed for each vehicle application for a complete tune-up repair.

Product Features:


    Product Features:
    • Complete set of boots for a complete tune-up and better value
    • OE design provides an exact fit for your application
    • Provides excellent heat resistance as well as maximum protection against spark loss
    • Durable silicone compound for resistance to high heat or abrasion
    • Spring included with the coil boot
    • Design for direct compatibility
See More

NGK – Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability (Part No.95605)

Ruthenium HX Spark Plug (LTR7BHX): High Ignitability & Durability

from

$17.99
NGK Ruthenium HX High Ignitability spark plugs are the best in class plug for todays modern vehicles. Patented Ruthenium technology offers the most advance tip technology and delivers the highest performance and life expectancy. Created from advanced OE technology as a high ignitability plug, Ruthenium HX spark plugs come with patented, specialized OEM DFE and PSPE tip designs. NGK Ruthenium HX High Ignitability spark plugs provide a more complete fuel burn resulting in a quicker throttle response, smoother idle and better cold starts. Ruthenium center electrode provides industry leading durability.

Product Features:
  • HIGH IGNITABILITY PROJECTED SQUARE PLATINUM ELECTRODE DESIGN: Combines 0.6 millimeter ruthenium center with a unique cut-back PSPE ground electrode
  • RUTHENIUM ALLOY CENTER ELECTRODE: NGK’s patented ruthenium technology produces maximum performance, ignitability & durability at high temperatures
  • PSPE DESIGN: Projected square platinum electrode shape of the ground electrode provides the best ignitability and service life for high heat engines
  • SOLID COPPER CORE: 98% pure copper core offers superior heat dissipation, conductivity and ultra wide heat ranges
  • TRIVALENT METAL PLATING: Delivers superior anti-corrosion and anti-seizing properties, ensuring ease of installation and removal
  • RECOMMENDED USAGE: Modern vehicles using OE PSPE type spark plugs or for those seeking an aftermarket plug with the latest OE technology
  • Enhanced Fuel Burn: Provides a more complete fuel burn, resulting in quicker throttle response, smoother idle, and better cold starts.
  • Industry-Leading Durability: Ruthenium center electrode ensures exceptional durability and longevity.
See More

Dorman – Help – Ignition Cylinder Actuator (Part No.47510)

Ignition Cylinder Actuator

from

$31.99
This ignition switch actuator is designed to match the appearance and function of the original actuator on specified applications, and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this ignition switch actuator is made to match the fit and performance of the original actuator on specific vehicle applications
  • Ideal solution – this actuator is a reliable replacement for an original part that has failed due to fatigue
  • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
  • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
See More

Dorman – Help – Coil Pack Mounting Bolt Kit – Pack of 8 Bolts (Part No.23751)

Coil Pack Mounting Bolt Kit - Pack of 8 Bolts

from

$17.49
This ignition coil mounting hardware is designed to match the fit, function and performance of the original equipment hardware on specified vehicles. It is engineered to help ensure a coil or coil pack is secured to the required under hood component.

Product Features:
  • Direct replacement – this ignition coil mounting hardware is designed to match the fit, function and performance of the original equipment hardware on specified vehicles
  • Ideal solution – engineered to help ensure a coil or coil pack is secured to the required under hood component when a coil or coil pack is replaced or when the original hardware is corroded or missing
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
  • Packaging Contents: 8 Bolts
See More

Helping You Find the Right Ignition and Tune-Up Products for Your Ford E-350 Super Duty

You love your E-350 Super Duty. So we’ve made it easier than ever to help you find Ford E-350 Super Duty Ignition and Tune-Up Products in our online catalog. Our inventory holds 144 aftermarket and OEM Ignition and Tune-Up Products for your Ford E-350 Super Duty, ranging from $3.49 to $972.99.

We offer parts from 17 brands trusted to make quality Ignition and Tune-Up Products for your Ford E-350 Super Duty. Before you buy, take some time to read through customer reviews. We currently have 136,941 reviews of Ford E-350 Super Duty Ignition and Tune-Up Products from previous customers. Some of the top rated parts include Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece with 4.7 stars and Iridium IX Spark Plug (TR55IX): Outstanding Acceleration & Durability with 4.8 stars.

Find your E-350 Super Duty Ignition and Tune-Up Products here, order online, and have your order shipped directly to your home. Prefer to have an in-person look at your Ford E-350 Super Duty part to confirm it’s just right? You can find your nearest Advance Auto Parts store and confirm they have the part in stock before heading over.

Top Ignition and Tune-Up Products Brands for Your Ford E-350 Super Duty

Our inventory holds Ignition and Tune-Up Products for your Ford E-350 Super Duty from 17 trusted brands. You’ll find OEM and aftermarket parts from brands like NGK, Motorcraft, and Autolite, all of which can keep that Ford happy.
We have ACDelco parts available for your Ford E-350 Super Duty in categories like Spark Plugs. Some of the top-rated ACDelco parts in these categories are:
Double Platinum Spark Plug
from $11.49
(21)
Double Platinum Spark Plug
Spark Plugs
RAPIDFIRE Spark Plug
from $7.99
(10)
RAPIDFIRE Spark Plug
Spark Plugs

Top-Rated NGK Ignition and Tune-Up Products

Leading NGK Ignition and Tune-Up Products

We carry NGK brand parts for your Ford E-350 Super Duty across several catalog categories, including Spark Plugs. Some of our most reviewed NGK parts include:

FAQs for Ford E-350 Super Duty Ignition and Tune-Up Products

What are the most purchased Ignition and Tune-Up Products for the Ford E-350 Super Duty?

Out of 144 Ignition and Tune-Up Products for the Ford E-350 Super Duty, the most popular in our inventory are:

What are the top-rated Ford E-350 Super Duty Ignition and Tune-Up Products?

Top-rated Ignition and Tune-Up Products for your Ford E-350 Super Duty based on customer reviews/ratings are:
Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece
from $93.99
(118)
Ignition Coil: Meets or Exceeds Original Equipment Specifications, 1 Piece
“Replacement part for my vehicle.”
Iridium IX Spark Plug (TR55IX): Outstanding Acceleration & Durability
from $14.99
(103)
Iridium IX Spark Plug (TR55IX): Outstanding Acceleration & Durability
“Works great. perfect fit”
Platinum TT Spark Plug - PT16TT
from $6.59
(90)
Platinum TT Spark Plug – PT16TT
“Worked well”