2025 Lexus IS300 Fluids and Chemicals

Essential Fluids and Chemicals for 2025 Lexus IS300s

LIQUI MOLY – Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter (Part No.2004)

Top Tec 4200 5W-30 Full Synthetic Motor Oil, Reduces Oil Consumption, 1 Liter

from

$16.99
High-tech low-friction motor oil based on synthetic technology. Ensures excellent engine cleanliness and exceeds even the strictest test requirements of well-known vehicle manufacturers. Reduces the build-up of troublesome deposits in direct-injection gasoline and diesel engines (FSI, TDI, common rail, etc.) and keeps oil consumption low. Assures reliable operation and maximizes the operating life of the diesel particulate filter (DPF). Specifically for vehicles with extremely long oil change intervals (WIV, etc.). Outstanding protection against wear, reduces oil and fuel consumption and ensures fast oil penetration of the engine.

Product Features:
  • Outstanding protection against wear
  • Reduces oil and fuel consumption
  • Ensure fast oil penetration of the engine
  • High tech low friction based on synthetic technology
  • Made in germany
  • Full Synthetic Oil Composition
See More

Valvoline – Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart (Part No.881159)

Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart

from

$29.99
Valvoline Daily Protection Motor Oil is specially formulated to exceed industry standards for wear, deposit and sludge protection to help keep engines running like new. Developed with high quality additives and premium base oils, it’s designed to flow easily at cold temperatures, reducing wear at startup and providing added protection against motor oil breakdown in tough conditions. For enhanced fuel efficiency, choose Daily Protection Synthetic Blend 5W-20 or 5W-30. Developed with low-friction technology to support strong fuel economy.

Product Features:
  • Extra wear protection designed to help keep automotive engine parts like new
  • Added detergents help protect against sludge and deposits
  • High quality additives resist motor oil breakdown in tough conditions
  • Low-friction formula supports strong fuel efficiency
  • Premium formulation flows easily at low temperatures reducing wear at start-up
See More

Mobil 1 – High Mileage 5W-30 Full Synthetic Motor Oil, Extends Engine Life, 1 Quart (Part No.14999)

High Mileage 5W-30 Full Synthetic Motor Oil, Extends Engine Life, 1 Quart

from

$11.99
Give your higher mileage engine the care it deserves with Mobil 1 High Mileage full-synthetic motor oil 0W-20. This formula utilizes Mobil 1’s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles with over 75,000 miles. Mobil 1 High Mileage motor oil extends engine life by reducing friction and preventing deposits and sludge buildup – keeping critical engine parts clean and protected for up to 10,000 miles between oil changes.(1) Mobil 1 helps to keep your engine running at lower temperatures(2) and is proven to cool engine temperatures by over 10%.(3) Mobil 1 High Mileage full-synthetic motor oil 5W-30 also helps control oxidation to prevent oil breakdown and is recommended by ExxonMobil for all types of modern cars, SUVs, light vans, and light trucks – including those with high-performance, turbocharged, supercharged, multi-valve, or fuel-injected engines. Mobil 1 is America’s No. 1 selling synthetic motor oil brand at retail, (4) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR®. ((1)Protects for up to 10,000 miles or 1 year, whichever comes first. To learn more about the Mobil 1 Limited Warranty, visit Mobil.US. (2)Compared to conventional oil. (3) Based on proprietary engine testing results may vary. (4) Source: The NPD Group/ Retail Tracking Service/ Dollar Sales/ PCMO full-synthetic/ 52 weeks ending September 30, 2023)

Product Features:
  • Mobil 1 High Mileage full-synthetic motor oil 5W-30 is designed for engines with over 75,000 miles to go up to 10,000 miles between oil changes (1)
  • Utilizes Mobil 1’s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness
  • Meets ILSAC GF-6 standards to help provide low-speed pre-ignition (LSPI) and timing chain wear protection while keeping your engine clean and helping to improve your fuel economy
  • Provides excellent internal engine heat protection (up to 500 degrees F) and low temperature protection (to -30 degrees F)
  • Helps extend engine life by working to prevent damaging deposits and sludge buildup
  • Manufacturer part number: 103767
See More

Pentosin – PENTOSIN ATF 44 5L (Part No.1058212)

PENTOSIN ATF 44 5L

from

$85.99
PENTOSIN ATF 44 5L

Royal Purple – High Performance 5W-30 Synthetic Motor Oil, Better Wear Protection, 1 Quart (Part No.01530)

High Performance 5W-30 Synthetic Motor Oil, Better Wear Protection, 1 Quart

from

$11.99
High Performance Motor Oil API LICENSED MOTOR OIL Royal Purple High Performance Motor Oil combines premium base oils with proprietary additive technologies to create a high performance synthetic engine oil that optimizes performance and protection. Royal Purple High Performance Motor Oils carry the current API and ILSAC engine oil licenses, as well as the GM dexos1 gasoline engine oil approval. ILSAC GF-6 AND GM DEXOS1 Modern gasoline direct injection (GDI) engines have achieved levels of power and fuel economy never before possible in passenger car engines. As a result, smaller engines operate at much higher loads across all engine speeds. This has caused increased wear in critical areas of the engine, and created a destructive phenomenon called low-speed pre-ignition (LSPI). The unique, state-of-the-art additive technology in Royal Purple High Performance engine oils is designed specifically to address these issues, and help engines maintain performance and reliability.

Product Features:
  • Better Wear Protection
  • Increased Protection against Low Speed Pre-Ignition
  • Increased Fuel Efficiency
  • Better Protection for Vehicle Exhaust Emissions Equipment
  • Improved Compatibility with Fuels Containing Ethanol
  • Superior Corrosion Protection
  • Made in USA
See More

Valvoline – High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon (Part No.773732)

High Performance Transmission & Differential Gear Oil: Conventional 80W-90, 1 Gallon

from

$32.99
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:
  • HIGH PERFORMANCE EXTREME-PRESSURE ADDITIVES HELP MINIMIZE WEAR in high pressure and high temperature conditions
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION can easily handle both winter and summer conditions for dependable coverage and protection year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • SUPERIOR ADDITIVES help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions
See More

Quaker State – 5W-30 Synthetic Blend Motor Oil, Reduces Engine Wear, 5 Quart (Part No.550044963)

5W-30 Synthetic Blend Motor Oil, Reduces Engine Wear, 5 Quart

from

$26.99
Quaker State 5W-30 motor oil is a synthetic blend formulation that helps engines survive daily commutes from high-speed highway operation to repetitive, stop-and-go driving. It maintains the required viscosity from start to finish, providing optimal protection. Quaker State Motor Oil combats engine sludge and deposits, providing rust protection from harmful acids generated by engine contaminants. It reduces engine wear, providing durable wear protection. Quaker State 5W-30 Motor Oil meets or exceeds the following OEM requirements: Chrysler MS-6395; Ford WSS M2C946-A, Ford WSS M2C946-B1; GM 6094M. It exceeds the requirements of the following industry specifications: API SP and all previous categories; ILSAC GF-6a and all previous ILSAC standards. For a full list of equipment approvals and recommendations, please consult your local Quaker State Technical Help Desk and always consult your owner’s manual.

Product Features:
  • Synthetic blend 5W-30 engine oil that provides durable wear protection and reduces engine wear
  • Provides corrosion protection against harmful acids generated by engine contaminants
  • Maintains viscosity from start to finish, providing optimal oil film protection
  • Helps engines survive daily commutes from high-speed highway operation to repetitive, stop-and-go driving
  • Combats engine sludge and deposits
  • Formulated to exceed industry specifications: ILSAC GF-6A, API SP/SP-Resource Conserving and all previous categories
  • Meets OEM requirements: Chrysler MS-6395, Ford WSS M2C946-A, Ford WSS M2C946-B1, GM 6094M
  • Formerly known as Quaker State Advanced Durability 5W-30 motor oil
  • Synthetic Blend Formulation: Quaker State 5W-30 motor oil is a synthetic blend that helps engines endure daily commutes, from high-speed highway driving to repetitive stop-and-go traffic.
See More

Mobil 1 – Extended Performance 5W-30 Full Synthetic Motor Oil, Protects Up to 20,000 Miles, 5 Quart (Part No.14977)

Extended Performance 5W-30 Full Synthetic Motor Oil, Protects Up to 20,000 Miles, 5 Quart

from

$41.99
If you trust your vehicle to be there for you, you need to be there for its engine, with Mobil 1 Extended Performance full-synthetic motor oil 5W-30. Our ultimate full-synthetic motor oil meets or exceeds the industry’s toughest standards to help you get the most from your engine for up to 20,000 miles between oil changes, guaranteed.(1) Utilizes Mobil 1’s Triple Action+ Formula to combine outstanding engine performance, protection, and cleanliness with the added benefit of maximized engine power. This cutting-edge formula is recommended by ExxonMobil for all types of modern vehicles, including high-performance, turbo-charged, and supercharged gasoline and diesel multi-valve fuel-injected engines found in passenger cars, SUVs, light vans, and light trucks. Mobil 1 is America’s No. 1 synthetic motor oil brand at retail,(2) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR®. ((1)Protects for up to 20,000 miles or 1 year, whichever comes first. To learn more about the Mobil 1 Limited Warranty, visit Mobil.US.(2)Source: The NPD Group/Retail Tracking Service/Dollar Sales/PCMO full-synthetic/52 weeks ending Feb 25, 2023)

Product Features:
  • Mobil 1 Extended Performance full-synthetic motor oil 5W-30 helps protect critical engine parts for up to 20,000 miles between oil changes, (1) controlling oxidation to prevent oil breakdown and maintaining excellent viscosity.
  • Utilizes Mobil 1’s Triple Action+ Formula to combine outstanding engine performance, protection, and cleanliness with the added benefit of power
  • Meets ILSAC GF-6 standards to help provide low-speed pre-ignition (LSPI) and timing chain wear protection while keeping your engine clean and helping to improve your fuel economy
  • Helps extend engine life by working to prevent damaging deposits and sludge buildup
  • Provides excellent internal engine heat protection (up to 500 degrees F) and low temperature protection (to -40 degrees F)
  • Manufacturer Part Number: 120766
  • Versatile Compatibility: Recommended for all types of modern vehicles, including high-performance, turbo-charged, and supercharged gasoline and diesel multi-valve fuel-injected engines in passenger cars, SUVs, light vans, and light trucks.
  • Trusted Brand: Mobil 1 is America’s No. 1 synthetic motor oil brand at retail, trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR«.
See More

Valvoline – High Mileage 10W-30 Synthetic Blend Engine Oil, Maximize Engine Life, 5 Quart (Part No.881161)

High Mileage 10W-30 Synthetic Blend Engine Oil, Maximize Engine Life, 5 Quart

from

$29.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • Maxlife technology prevents engine breakdown with 40% better wear protection than the industry standard
  • Refresh aging seals and prevent leaks with seal conditioners
  • Reduce sludge, deposits, corrosion, and rust with added detergents – keep motors clean inside
  • Enhanced friction performance helps maximize power with advanced friction-fighting agents
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • MaxLife Technology: The exclusive formula of Valvoline High Mileage with MaxLife Technology Engine Oil is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles.
See More

Valvoline – Extended Protection Automatic Transmission Fluid, 1 Quart (Part No.899179)

Extended Protection Automatic Transmission Fluid, 1 Quart

from

$14.99
Modern transmissions are better than ever, with more gears to help improve fuel efficiency and acceleration. Greater performance calls for greater protection. Valvoline Extended Protection Full Synthetic ATF features our exclusive Dual Defense Additive Technology for two layers of protection against metal-on-metal contact and thermal breakdown, all while minimizing wear on clutch components. In fact, Valvoline Extended Protection Full Synthetic ATF is 45% stronger against breakdown compared to major brand DEX/MERC oxidative PDSC performance. Proven to maximize transmission life, our patented formula is suitable for use in 92% of vehicles in light duty automatic transmissions 2010 and newer. Keep your modern vehicle shifting smoothly, mile after mile, with the ultimate protection you can only expect from Valvoline, the #1 ATF brand.

Product Features:
  • The ultimate protection for your automatic transmission
  • 45% stronger against breakdown
  • Dual Defense Additive Technology combines friction modifiers and anti-wear additives for two layers of protection
  • Suitable for use in over 92% of vehicles in light duty automatic transmissions 2010 and newer
See More

Prestone – Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 oz. (Part No.AS263Y)

Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 oz.

from

$11.79
Prestone Power Steering Fluid + Stop Leak (PSF+SL) delivers increased system life and prevents and stops system leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. The stop leak additives also prevent leaks by rejuvenating seals before they leak. Also designed with Anti-wear System Protection, Prestone PSF+SL protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 50,000 Mile Fluid Life
  • Includes Stop Leak Additives to prevent and stop power steering system leaks.
  • Anti-Wear Protection = Increased System Life. Protects against pump failure, squeals and clogs. Corrosion protection for metals, rubber and gasket components.
  • Conventional Formula – For use in all manufacturers
See More

Prestone – Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 oz. (Part No.AS261Y/1)

Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 oz.

from

$9.99
Prestone Power Steering Fluid (PSF) delivers increased system life. Designed with Anti-wear System Protection, Prestone PSF protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 50,000 Mile Fluid Life
  • Anti-Wear Protection = Increased System Life. Protects against pump failure, squeals and clogs. Corrosion protection for metals, rubber and gasket components.
  • For use in all manufacturers
  • Conventional Formula – For use in all manufacturers
See More

Valvoline – Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.820681)

Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$36.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON®, GM DEXRON®-II and DEXRON®-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III , Toyota/Lexus Type T, T-III and T-IV , Honda/Acura ATF-Z1 (except in CVTs) , Mercedes Benz NAG1 , Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Prestone – MAX Power Steering Fluid: Asian Vehicles, With Stop Leak, Restores Seals, 100k miles, 12 oz. (Part No.AS279)

MAX Power Steering Fluid: Asian Vehicles, With Stop Leak, Restores Seals, 100k miles, 12 oz.

from

$14.99
Prestone MAX Asian Vehicles Power Steering Fluid (PSF) + Stop Leak maximizes and increases system life + the power to stop leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. This formula is also great at preventing leaks by rejuvenating seals before they leak. This synthetic fluid is designed with 2X Anti-wear System Protection, which means more protection against pump failure, squeals and clogs. 100,000 mile fluid life, 2X more than conventional fluid, extends the time between replacement. This fluid is formulated for Asian vehicle manufacturers: Toyota, Lexus, Honda, Acura, Nissan, Infiniti, Kia, Hyundai, Subaru, Mazda, Suzuki and others. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 100,000 Mile Fluid Life. Synthetic Formula for longer life and more protection
  • MAX + Stop Leak. Stop Leak Additives to prevent and stop power steering system leaks.
  • For use in Asian vehicle manufacturers: Toyota, Lexus, Honda, Acura, Nissan, Infiniti, Kia, Hyundai, Subaru, Mazda, Suzuki and others
  • 2X Anti-Wear Protection for enhanced System Life vs. conventional fluid. More protection against pump failure, squeals and clogs
See More

Castrol – Transmax Automatic Transmission Fluid, Smooth Performance, 1 Quart (Part No.15ADFA)

Transmax Automatic Transmission Fluid, Smooth Performance, 1 Quart

from

$7.99
Product Features:
  • Enhanced friction durability for smooth transmission performance
  • Meets DEXRON«-III H requirements; also satisfies requirements of DEXRON«, DEXRON«-III, IIE, and II; do not use this ATF in applications calling for DEXRON«-VI
  • Meets MERCON« requirements; may also be used in power steering applications where MERCON« is required; use Castrol Type F ATF in applications calling for Type F
  • Do not use this ATF in applications calling for MERCON« V or MERCON« SP
  • Packaged in a convenient 1-quart size for easy handling and precise fluid measurement during maintenance.
See More

Castrol – Transmax High Mileage Transmission Fluid, Restores Smooth Shifting, 1 Gallon (Part No.1599F1)

Transmax High Mileage Transmission Fluid, Restores Smooth Shifting, 1 Gallon

from

$49.99
Product Features:
  • Additional seal conditioners to prevent or help stop leaks
  • Extra cleaning agents to reduce varnish and sludge formulation
  • Protects against clutch wear
  • Restores smooth shifting
  • Greater frictional durability provides superior transmission performance
  • Can be used in a wide variety of specifications including DEXRON«-IIIH, MERCON«áand JASO-1A.
  • Exceeds all passenger car and light truck manufacturer┐s warranty requirements for vehicles, transmissions or power steering service where a DEXRON«-IIIH or MERCON« type ATF is specified
See More

Valvoline – MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$35.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base oils and long life friction modifiers to help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Valvoline – DEXRON®-VI ATF Full Synthetic Automatic Transmission Fluid, 1 Gallon (Part No.883572)

DEXRON®-VI ATF Full Synthetic Automatic Transmission Fluid, 1 Gallon

from

$38.99
Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, MERCON LV and Allison C-4.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$9.99
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
See More

Prestone – Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup and Rust, 1 Gallon (Part No.AF2000)

Antifreeze and Coolant: Concentrate, Universal, Protects Against Buildup and Rust, 1 Gallon

from

$17.99
Prestone All Vehicles antifreeze+coolant (concentrate) is truly designed to work with all vehicles; all makes, models, years and fluid colors. It is designed to work with all new engines, while also being backwards compatible improving protection in all older engines. The patented Cor-Guard technology (the best innovation in the category in decades) instantly protects parts from corrosion, buildup, pitting, scaling, rust and other damage. Prestone’s Antifreeze + Coolants are designed to the highest standards using state of the art technology. These fluids are specially designed to not only manage the engine temp and protect from freezing up (like competitors), but they also protect the engine from damage. internal damage can cause engine part failure, expensive repairs and serious inconveniences . Avoid costly repairs and vehicles in the shop with Prestone All Vehicles antifreeze+coolant. This fluid is designed to last 10yrs/300,000 miles and also to protect the internal parts of the engine for 10yrs/300,000, officially patented by Prestone.

Product Features:
  • Formulated to work with All Vehicles. Works with all fluid colors; All OAT, POAT, HOAT and IAT.
  • Longer Engine Life Guarantee – 10 year/300,000 mile Extended life formula.
  • Includes patented Prestone CorGuard technology, the best advancement in cooling system parts protection that protects against rust and corrosion of all cooling system metals, including aluminum. Protection for 300,000 miles.
  • Concentrate formula. Must mix with distilled to the desired mix ratio of EG and water. Can be used for top-off, complete drain and refill or flush and refill of the cooling system.
See More

ZEREX – G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon (Part No.ZXG051)

G05® Full Strength Concentrate Antifreeze / Coolant, 1 Gallon

from

$22.99
ZEREX G05® is the automaker approved original chemistry used in newer Ford®, Chrysler® and Mercedes-Benz® automotive and diesel engines. Its Hybrid Organic Acid Technology (HOAT) chemistry combines the best of conventional and organic acid-based chemistry to provide the ultimate protection against rust and corrosion. ZEREX G05 antifreeze/coolant uses the highest-quality virgin ethylene glycol for freeze and boil over protection and a hybrid organic acid corrosion inhibitor package to protect your engines from liner pitting and corrosion.

Product Features:
  • Automaker approved technology. Provides protection for 5 years / 150,000 miles in light duty applications and 3 years / 300,000 miles in heavy duty applications.
  • Formulated for long life performance
  • Low-silicate, low-pH and phosphate-free formula
  • Helps protect all cooling system metals, including aluminum
See More

Prestone – Antifreeze and Coolant: 50/50 Ready-to-Use, Universal Platinum, 1 Gallon (Part No.AF2550)

Antifreeze and Coolant: 50/50 Ready-to-Use, Universal Platinum, 1 Gallon

from

$19.99
Prestone Platinum antifreeze+coolant is Prestone’s best universal antifreeze and coolant product. Guaranteed to work with all vehicles; all makes, models, years and fluid colors. 15+ years, 350,000 miles of protection; the fluid is Guaranteed for the life of your vehicle. This advanced product delivers Extreme Protection against both freezing temperatures (-50 deg.) and overheating/boiling over of the engine (+268 deg.). Prestone Platinum utilizes industry leading protection from engine damaging rust, corrosion, buildup and scale. While ordinary antifreeze coolant only focuses on the basic corrosion coverage, Prestone Platinum goes farther, adding our most advanced cooling system protection, allowing the system to run optimally, like when it was new. Internal buildup and corrosion damage can cause engine part failure or clogging, leading to expensive repairs and inconveniences. Prestone Platinum helps you avoid costly repairs and vehicles in the shop. This extended life coolant is Guaranteed to work with all new engines and engine technology, while also being backwards compatible, improving protection in all older engines. Prestone Platinum antifreeze+coolant – Year Round Protection.

Product Features:
  • Guaranteed to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT and IAT; G05, G11, G12, G12++, G13, G30, G40, and GG40. For all engines and engine sizes, new and older engines.
  • 15+ year/350,000 mile Extended life formula. The fluid is guaranteed for the life of your vehicle
  • Includes our most advanced Prestone Cor-Guard technology, unmatched cooling system parts protection that protects against engine damage; rust, corrosion, scale, build-up and clogging. Protection for 15+yrs/350,000 miles.
  • Ready to Use formula – Prediluted 56/54. Perfect for small volume top-off or complete drain and refill of the cooling system
See More

Prestone – Antifreeze and Coolant: Concentrate, Universal Platinum, Protects Against Corrosion, 1 Gallon (Part No.AF2500)

Antifreeze and Coolant: Concentrate, Universal Platinum, Protects Against Corrosion, 1 Gallon

from

$22.99
Prestone Platinum antifreeze+coolant is Prestone’s best universal antifreeze and coolant product. Guaranteed to work with all vehicles; all makes, models, years and fluid colors. 15+ years, 350,000 miles of protection; the fluid is Guaranteed for the life of your vehicle. This advanced product delivers Extreme Protection against both freezing temperatures (-50 deg.) and overheating/boiling over of the engine (+268 deg.). Prestone Platinum utilizes industry leading protection from engine damaging rust, corrosion, buildup and scale. While ordinary antifreeze coolant only focuses on the basic corrosion coverage, Prestone Platinum goes farther, adding our most advanced cooling system protection, allowing the system to run optimally, like when it was new. Internal buildup and corrosion damage can cause engine part failure or clogging, leading to expensive repairs and inconveniences. Prestone Platinum helps you avoid costly repairs and vehicles in the shop. This extended life coolant is Guaranteed to work with all new engines and engine technology, while also being backwards compatible, improving protection in all older engines. Prestone Platinum antifreeze+coolant – Year Round Protection.

Product Features:
  • Guaranteed to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT and IAT; G05, G11, G12, G12++, G13, G30, G40, and GG40. For all engines and engine sizes, new and older engines.
  • 15+ year/350,000 mile Extended life formula. The fluid is guaranteed for the life of your vehicle
  • Includes our most advanced Prestone Cor-Guard technology, unmatched cooling system parts protection that protects against engine damage; rust, corrosion, scale, build-up and clogging. Protection for 15+yrs/350,000 miles.
  • Concentrated formula. Must mix with high quality water to the desired ratio. Can be used for top-off, complete drain and refill or flush and refill of the cooling system.
See More

FRAM – All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon (Part No.F401)

All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon

from

$10.99
FRAM Extended Life AMAM 50/50 is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with FRAM Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. FRAM 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT and IAT
  • 5 year/150,000 mile Extended life formula.
  • Meets or exceeds ASTM D3306 and D4985 for corrosion protection.
  • Ready to Use formula (prediluted to a 50% Eg and 50% distilled water mix). Perfect for small volume top-off or complete drain and refill of the cooling system
See More

ZEREX – Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon (Part No.675130)

Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon

from

$22.99
ZEREX Asian Vehicle Antifreeze/Coolant is specifically formulated to meet the requirements of Asian vehicle manufacturers (Toyota®, Lexus®, Scion® and others) requiring a red, silicate free Hybrid Organic Acid Technology (HOAT) with a phosphate additive. This patented formula is designed to replace the original fluid and provides protection from rust, corrosion, boil overs and freezing.

Product Features:
  • Formulated to replace the OEM fluid in Asian make vehicles such as Toyota®, Lexus®, Scion® and others requiring a red, silicate free HOAT antifreeze/coolant
  • Silicate-free, long-life, phosphate Hybrid Organic Acid Technology chemistry
  • The long life formula provides protection for all cooling system metals from rust and corrosion. The silicate free, borate free formula helps protect against harmful scale and deposits
  • Meets the following OEM and industry specifications: JIS K 2234-1994, Hyundai/KIA MS 591-08, Mitsubishi ES-64217, Ford WSS-M97B55-A, ASTM 3306, ASTM D4985, Federal Specification A-A-870A
See More

ZEREX – G-05 Formula 50/50 Pre-Mixed RTU Antifreeze / Coolant, 1 Gallon (Part No.ZXG05RU1)

G-05 Formula 50/50 Pre-Mixed RTU Antifreeze / Coolant, 1 Gallon

from

$19.99
ZEREX G05® is the automaker approved original chemistry used in newer Ford®, Chrysler® and Mercedes-Benz® automotive and diesel engines. Its Hybrid Organic Acid Technology (HOAT) chemistry combines the best of conventional and organic acid-based chemistry to provide the ultimate protection against rust and corrosion. ZEREX G05® antifreeze/coolant uses the highest quality virgin ethylene glycol for freeze and boil over protection and a hybrid organic acid corrosion inhibitor package to protect your engines from liner pitting and corrosion.

Product Features:
  • Automaker approved technology. Provides protection for 5 years / 150,000 miles in light duty applications and 3 years / 300,000 miles in heavy duty applications
  • Formulated for long life performance
  • Low-silicate, low-pH and phosphate-free formula
  • Helps protect all cooling system metals, including aluminum
See More

Prestone – MAX Original Equipment Antifreeze + Coolant: Asian Red/Pink, 50/50 Ready-to Use, 1 Gallon (Part No.AF6210)

MAX Original Equipment Antifreeze + Coolant: Asian Red/Pink, 50/50 Ready-to Use, 1 Gallon

from

$20.99
Prestone MAX antifreeze + coolant uses Advanced Original Equipment Technology to provide maximum engine protection for Asian vehicles requiring Red or Pink antifreeze + coolant, Guaranteed. Our Advanced Technology formula delivers high performance temperature protection, industry leading protection from engine damaging rust and corrosion and the longest lasting protection in the industry. Trust Prestone – a leading global manufacturer of Original Equipment Antifreeze + Coolant.

Product Features:
  • Can top off or replace any Red or Pink antifreeze + coolant in all Toyota, Lexus and Scion vehicles, guaranteed. 50/50 Ready to Use (RTU) formula.
  • High performance temperature protection from deep winter freezes and scorching summer heat.
  • Industry leading protection from engine damaging rust, corrosion and buildup. Prestone MAX completely stops the formation of rust and corrosion for better engine performance and longer engine life.
  • Prestone Max is guaranteed to protect your vehicle for 15+ years and/or 350,000 miles. It’s the longest fluid life in the industry.
See More

FRAM – Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon (Part No.F301)

Antifreeze & Coolant: Extended Life AMAM Antifreeze Concentrate, 1 Gallon

from

$14.99
FRAM Extended Life AMAM Concentrate is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. FRAM Concentrate meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Works with all fluid colors; All OAT, POAT, HOAT and IAT.
  • Longer Engine Life Guarantee – 5 year/150,000 mile Extended life formula.
  • Includes patented technology, the best advancement in cooling system parts protection that protects against rust and corrosion of all cooling system metals, including aluminum. Protection for 150,000 miles.
  • Concentrate formula. Must mix with distilled to the desired mix ratio of EG and water. Can be used for top-off, complete drain and refill or flush and refill of the cooling system.
See More

Upgrade your 2025 Lexus IS300 with Top-Quality Fluids and Chemicals

When it comes to maintaining or upgrading your 2025 Lexus IS300, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Fluids and Chemicals are key to keeping your IS300 functioning at its best. At Advance Auto Parts, we offer a wide selection of 10 Fluids and Chemicals for the 2025 Lexus IS300, designed to meet your needs without breaking the bank. From Fluid replacements to Transmission Fluids upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Fluids and Chemicals for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Fluids and Chemicals for your 2025 Lexus IS300 at great prices. Our Fluids and Chemicals inventory for this model ranges from just $9.99 to $104.99, with an average price of $30.54. Our 10 Fluids and Chemicals in stock come from 4 trusted brands, so you’re sure to find the right part for your 2025 Lexus IS300 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2025 Lexus IS300, we stock popular OEM and aftermarket Fluids and Chemicals from top names like Valvoline, ZEREX, Pentosin, and more. Valvoline Fluids and Chemicals start at just $9.99 and boast an impressive 4.8 stars average rating from customers. ZEREX and Pentosin also bring quality to the table, with Fluids and Chemicals available starting at $22.99, and at an average 4.8 stars rating. With 6,248 customer reviews and counting, our 2025 Lexus IS300 Fluids and Chemicals have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Fluids and Chemical upgrades. Explore related part types like Alternators and Starters, Filters and PCVs and more to make sure your 2025 Lexus IS300 is always ready to roll. We’re committed to providing you with everything you need to keep your IS300 in top shape, all in one place. Start shopping confidently below for your 2025 Lexus IS300!

Best-Selling Fluids for 2025 Lexus IS300s

Enhance the driving experience in your Lexus with 6 quality Fluid components, starting at $9.99.

Valvoline – MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$35.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base oils and long life friction modifiers to help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.VV324)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$9.99
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in 95% of vehicles. And now, it’s recommended for most belt & chain-driven continuously variable transmissions (CVT). Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is suitable for most Ford, GM, Toyota, Honda, Nissan, Hyundai, Subaru, BMW, Mercedes, Volvo, VW & Audi vehicles. Recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI, and DEX-CVT; Ford MERCON LV; Toyota/Lexus Type T, T-II, T-IV, WS, CVTF FE, and CVTF TC; Honda/Acura ATF-Z1 and Honda CVT; Nissan/Infiniti Matic-D, Matic-J, Matic-K and Matic-S; Hyundai/Kia SP-II, SP-III, SP-IV and SPH-IV; BMW 7045E, ETL 8072B, LA2634 and LT71141; Allison C-4; Mercedes-Benz NAG-1; Volvo 1161521, 1161540, 97340 and 1273.41; Subaru ATF HP, Lineartronic chain CVT and CVT-II, Lineartronic High Torque CVT, and CV-30; and VW/Audi G-052-025-A2 and G-052-162-A1. CURRENTLY UNABLE TO SHIP THIS PRODUCT TO CUSTOMERS LOCATED IN CALIFORNIA

Product Features:
  • FOR USE IN 95% OF VEHICLES INCLUDING MOST CVTs in operation with US registered light duty applications
  • HIGH PERFORMANCE CONDITIONING AGENTS prolong seal elasticity to prevent leaks
  • IMPROVED DURABILITY & TRANSMISSION LIFE with anti-wear technology to avoid costly repairs
  • ENHANCED HIGH & LOW TEMP PERFORMANCE supports transmission fluid in all weather situations
See More

Valvoline – Import Multi-Vehicle Synthetic Automatic Transmission Fluid, 1 Quart (Part No.822389)

Import Multi-Vehicle Synthetic Automatic Transmission Fluid, 1 Quart

from

$13.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON, GM DEXRON-II and DEXRON-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III, Toyota/Lexus Type T, T-III and T-IV, Honda/Acura ATF-Z1 (except in CVTs), Mercedes Benz NAG1, Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Valvoline – Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.820681)

Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$36.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON®, GM DEXRON®-II and DEXRON®-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III , Toyota/Lexus Type T, T-III and T-IV , Honda/Acura ATF-Z1 (except in CVTs) , Mercedes Benz NAG1 , Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Castrol – Transmax ATF/CVT Universal Transmission Fluid, Smooth Performance, 1 Gallon (Part No.15E0C8)

Transmax ATF/CVT Universal Transmission Fluid, Smooth Performance, 1 Gallon

from

$28.99
Castrol® Transmax® ATF/CVT Universal is a premium full-synthetic transmission fluid engineered for exceptional performance in both traditional step-shifting automatic transmissions and modern continuously variable transmissions (CVTs). Featuring Castrol Smooth Drive® Technology, it ensures enhanced friction durability for seamless gear shifts and superior high-temperature protection to resist oxidation. This advanced formulation offers unmatched protection against copper corrosion, extending the life of your transmission system. Its broad compatibility covers a wide range of ATF and CVT applications, including Dexron VI, Mercon LV, Toyota WS, Honda DW-1, Nissan Matic S, and many more, making it ideal for diverse vehicle types, including hybrids. Designed to improve workshop efficiency and simplify inventory management, this fluid is a versatile solution for professional mechanics and DIY enthusiasts alike. Packaged in a convenient 1-gallon size, it delivers outstanding value and reliability for maintaining optimal transmission performance.

Product Features:
  • Enhanced friction durability for smooth transmission performance
  • Superior high temperature protection to effectively resist oxidation
  • Unsurpassed protection against copper corrosion
  • Broad scope of vehicle applications improves workshop efficiency and inventory management
  • ATF Applications: Dexron VI (Dexron III, Dexron), Mercon LV (Mercon SP, Mercon V, Mercon), JASO 1A (03), JASO 1A LV (13), Toyota T IV, Toyota T III, Toyota WS, Honda/Acura DW 1/Z 1, Nissan Matic D, Matic J, Matic S, Hyundai/Kia SP IV, SP III
  • ATF Applications: Mazda ATF M-V, M-III, FZ, Mitsubishi SP IV, SP III, IIM, II, PA, J3, VW/Audi (6, 8 & 9 speed automatics), BMW/Mini (6, 8 and 9 speed automatics), Jaguar/Land Rover (6, 8 & 9 speed automatics), Porsche (6, 8 & 9 speed automatics)
  • ATF Applications: Volvo (6, 8 and 9 speed automatics), Volvo Transmission Oil 97342, AT102, Mercedes-Benz (7 and 9 speed automatics)
  • CVT Applications: Toyota CVT Fluid TC, Toyota CVT Fluid FE , Nissan CVT Fluid NS-1, Nissan CVT Fluid NS-2, Nissan CVT Fluid NS-3, Subaru i-CVT Fluid, Subaru i-CVT FG, Subaru Lineartronic High Torque Chain CVTF, Honda HCF-2
See More

Valvoline – Extended Protection Automatic Transmission Fluid, 1 Quart (Part No.899179)

Extended Protection Automatic Transmission Fluid, 1 Quart

from

$14.99
Modern transmissions are better than ever, with more gears to help improve fuel efficiency and acceleration. Greater performance calls for greater protection. Valvoline Extended Protection Full Synthetic ATF features our exclusive Dual Defense Additive Technology for two layers of protection against metal-on-metal contact and thermal breakdown, all while minimizing wear on clutch components. In fact, Valvoline Extended Protection Full Synthetic ATF is 45% stronger against breakdown compared to major brand DEX/MERC oxidative PDSC performance. Proven to maximize transmission life, our patented formula is suitable for use in 92% of vehicles in light duty automatic transmissions 2010 and newer. Keep your modern vehicle shifting smoothly, mile after mile, with the ultimate protection you can only expect from Valvoline, the #1 ATF brand.

Product Features:
  • The ultimate protection for your automatic transmission
  • 45% stronger against breakdown
  • Dual Defense Additive Technology combines friction modifiers and anti-wear additives for two layers of protection
  • Suitable for use in over 92% of vehicles in light duty automatic transmissions 2010 and newer
See More

Most Popular 2025 Lexus IS300 Transmission Fluids

Customize your Lexus with 2 Transmission Fluids products like Manual Transmission Fluids, all priced under $104.99.

Valvoline – Full Synthetic High Mileage 0W-20 Engine Oil, Maximizes Engine Life, 1 Quart (Part No.852400)

Full Synthetic High Mileage 0W-20 Engine Oil, Maximizes Engine Life, 1 Quart

from

$11.49
Upgrading your motor oil to Valvoline Full Synthetic High Mileage with MaxLife Technology can help you increase the longevity of your car, truck or SUV with over 75,000 miles. It’s proven to protect your high-mileage motor against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repairs. Our exclusive formulation goes beyond industry standards to protect your engine. It’s fortified with enhanced wear additives and friction-fighting agents to safeguard critical engine components, extra detergents to clean inside your engine, and premium seal conditioners to restore aging seals and prevent leaks. Superior viscosity modifiers and high-quality base oils help it perform exceptionally in both high and low temperatures. Engineered with ingenuity, tested with tenacity, and proven with purpose, our formula was innovated in America with a century and a half of hands-on experience from the original motor oil brand.

Product Features:


Product Features:
  • Enhanced maxlife technology prevents engine breakdown in extreme conditions with 50% better wear protection than the industry standard
  • Treat and prevent leaks with premium seal conditioners to keep oil out of places it shouldn’t be
  • 25% extra defense against deposits, sludge, corrosion and rust via interior-cleansing detergents
  • Extreme temperature protection through our high-quality base oils and superior viscosity modifiers
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • High Mileage Protection: Valvoline Full Synthetic High Mileage with MaxLife Technology is specifically designed to protect engines with over 75,000 miles against wear, friction, heat, and deposits – the leading causes of engine breakdown
See More

Valvoline – High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon (Part No.881048)

High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon

from

$104.99
If you have over 75,000 miles, you need the superior protection of America’s first high mileage Motor Oil. Valvoline High Mileage MaxLife helps extend the life of your vehicle by fighting the four major signs of engine wear – reduced power, loss of fuel economy, oil leaks and increased oil consumption. The synthetic blend formula contains extra additives designed to combat these problems unique to aging cars and trucks. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition.

Product Features:


Product Features:
  • Seal conditioners rejuvenate aging engine seals to help stop and prevent oil leaks
  • Extra wear protection helps prevent future engine wear
  • Extra detergents help keep older engines cleaner by bonding with and removing sludge and deposits
  • Anti-oxidants help prevent oil breakdown, preventing engine-clogging sludge and deposit formation
  • Designed to combat low-speed pre-ignition in gasoline direct-injected engines, ensuring optimal performance and protection for modern aging vehicles.
See More

Top Picks for 2025 Lexus IS300 Coolant/Antifreeze

Upgrade Lexus IS300s with top-quality Coolant/Antifreeze parts, including 2 OEM and aftermarket selections for your 2025 model.

ZEREX – Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon (Part No.675130)

Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon

from

$22.99
ZEREX Asian Vehicle Antifreeze/Coolant is specifically formulated to meet the requirements of Asian vehicle manufacturers (Toyota®, Lexus®, Scion® and others) requiring a red, silicate free Hybrid Organic Acid Technology (HOAT) with a phosphate additive. This patented formula is designed to replace the original fluid and provides protection from rust, corrosion, boil overs and freezing.

Product Features:
  • Formulated to replace the OEM fluid in Asian make vehicles such as Toyota®, Lexus®, Scion® and others requiring a red, silicate free HOAT antifreeze/coolant
  • Silicate-free, long-life, phosphate Hybrid Organic Acid Technology chemistry
  • The long life formula provides protection for all cooling system metals from rust and corrosion. The silicate free, borate free formula helps protect against harmful scale and deposits
  • Meets the following OEM and industry specifications: JIS K 2234-1994, Hyundai/KIA MS 591-08, Mitsubishi ES-64217, Ford WSS-M97B55-A, ASTM 3306, ASTM D4985, Federal Specification A-A-870A
See More

Pentosin – Pentofrost A4 HOAT Phosphated Asian 50/50 Prediluted Antifreeze / Coolant – 1 Gallon (Part No.8115209)

Pentofrost A4 HOAT Phosphated Asian 50/50 Prediluted Antifreeze / Coolant - 1 Gallon

from

$24.99
Pentofrost A4 is a phosphated organic acid technology (phosphated OAT); which is categorized as HOAT (hybrid organic acid technology) in the US market. Pentofrost A4 is suitable for all Asian vehicles using pink Antifreeze/Coolant. Pentofrost A4 does not contain any silicate, borate, nitrite or amine containing additives since these may harm your Asian vehicle. Do not mix with other coolants (especially silicated coolants), as this may cause el formation and clog your radiator. Pentofrost A4 is a PRE-DILUTED antifreeze for Asian vehicle applications in water-cooled engines. It contains phosphates and organic salts to protect all materials used in cooling systems for Asian vehicles. Pentofrost A4 is mixable with all phosphated OAT. Meets ASTM D-3306.

Product Features:
  • Manufactured to the OE applications specific formulation.
  • Manufactured to the exact spec of DIN and ASTM D-3306.
  • Protects against corrosion and cavitation.
  • Does not foam.
See More

Top-Rated Fluids and Chemicals Brands For Your 2025 Lexus IS300

Shop for the best-rated brands offering Fluids and Chemicals and other products for your 2025 Lexus IS300s. Below you’ll find some of our best rated Fluids and Chemicals from Valvoline, ZEREX, and Pentosin, and more. Fluids and Chemicals from these brands that fit a 2025 IS300 start at just $9.99 and are rated as high as 4.8 stars. OEM and aftermarket Fluids and Chemicals don’t get more top quality, durable, and affordable than from the brands below.

Popular Valvoline 2025 Lexus IS300 Fluids and Chemicals

When it comes to maintaining or upgrading your 2025 Lexus IS300, using quality Fluids and Chemicals is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Fluids and Chemicals, specifically designed for the 2025 Lexus IS300. With over 3 Valvoline brand Fluids and Chemicals in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $9.99, with an average price of just $19.16. Plus, with over 1,259 customer reviews and an average rating of 4.8 stars, you can trust that our Valvoline Fluids and Chemicals will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon
from $35.99
(446)
MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon
“Synthetic is the way to go”

Popular ZEREX 2025 Lexus IS300 Fluids and Chemicals

ZEREX auto parts is one of the highest quality Fluids and Chemical brands in the market. Any 2025 Lexus IS300 owner should feel confident when installing genuine ZEREX parts in their vehicle. To ensure the best fit and performance for your 2025 IS300, Advance Auto Parts carries a full inventory of 1 ZEREX Fluids and Chemicals. Plus you will be keeping your Lexus in peak condition while saving money because prices on these ZEREX Fluids and Chemicals range up to $22.99, plus, with more than 241 customer reviews and an impressive 4.8 stars average rating, you can be confident the Fram Fluids and Chemicals below will deliver on both quality and value.

FAQs for 2025 Lexus IS300 Fluids and Chemicals

Which Fluids and Chemicals are best-sellers for 2025 Lexus IS300s?

Out of 10 Fluids and Chemicals that fit 2025 Lexus IS300s, the following parts are the top sellers:

What’s the price range for 2025 Lexus IS300 Fluids and Chemicals?

Fluids and Chemical prices for the 2025 Lexus IS300 start at $9.99 and go up to $104.99 for the most premium parts.

What’s the average price of a Fluids and Chemical for a 2025 Lexus IS300?

The average price for Fluids and Chemicals for the 2025 Lexus IS300 is $30.54. Keep in mind the variety of part types within our Fluids and Chemical category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Fluids and Chemicals for other Lexus IS300 model years?

Yes, we currently carry Fluids and Chemicals for 13 model years of Lexus IS300s between 2001 and 2024. Fluids and Chemicals are bought most frequently for the following model years: 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, and 2005.

What are the cheapest Fluids and Chemicals for my 2025 Lexus IS300?

What are the top-rated Fluids and Chemicals that fit the 2025 Lexus IS300?

Out of 6,248 reviews by customers, our 2025 Lexus IS300 Fluids and Chemicals have an average customer rating of . These are some of the highest-rated Fluids and Chemical types for the 2025 Lexus IS300 and their top-rated products:

What types of Fluids and Chemicals do you sell for my 2025 Lexus IS300?

Can I get help with 2025 Lexus IS300 Fluids and Chemical orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Fluids and Chemicals and more.

What is your return policy for Lexus IS300 Fluids and Chemicals?

Advance Auto Parts keeps returns simple. For new Lexus IS300 Fluids and Chemicals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.