2022 Lexus RX350 Cooling and Climate Controls

Essential Cooling and Climate Controls for 2022 Lexus RX350s

Carquest Premium – Ambient Air Temperature Sensor (Part No.WTA1121)

Ambient Air Temperature Sensor

from

$43.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Santech – A/C Pressure Switch (Part No.R1054261110SII)

A/C Pressure Switch

from

$44.70
A/C Pressure Switch

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA1745)

A/C Refrigerant Pressure Sensor

from

$83.99
The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:
  • Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
  • Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
  • All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
  • All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging
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Carquest Premium – Radiator Cap: 16 PSI (Part No.10242)

Radiator Cap: 16 PSI

from

$14.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Sankei Switches – Sankei Switches Radiator Cap (Part No.G101045813SAK)

Sankei Switches Radiator Cap

from

$11.27
The Sankei Switches radiator cap range has been developed to operate within original equipment manufacturer’s specifications. A faulty radiator cap can cause your car to boil-over at a lower temperature. Test or replace the coolant cap when servicing the cooling system.

Product Features:
  • Meets Original Equipment specifications.
  • Made from premium materials.
  • Designed to function on open cooling systems and overflow reservoir type systems.
See More

Carquest Premium – New Compressor with Clutch, Nippondenso 7SAS17C (Part No.T168348)

New Compressor with Clutch, Nippondenso 7SAS17C

from

$465.99
High quality OE replacement part with all components needed to complete the job.

Product Features:
  • Endurance tested the equivalent of 50k miles
  • Includes specific electrical connector to eliminate splicing
  • Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
  • For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
  • Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
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KAI – A/C Compressor (Part No.ACP012708)

A/C Compressor

from

$999.99
New Standard Replacement A/C Compressor, 7SB19C, 7 Groove

Product Features:
  • 7SB19C, 7 Groove
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
See More

Carquest Premium – Blower Motor: With Wheel (Part No.75076)

Blower Motor: With Wheel

from

$123.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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VDO – Blower Motor (Part No.R2031283546VDO)

Blower Motor

from

$174.59
Blower Motor

Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 188 Degrees (Part No.1049-188)

Integrated Thermostat Housing: With Sensor, With Seal, 188 Degrees

from

$229.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees (Part No.902-5216)

Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees

from

$162.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models.
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813207)

Radiator: With Transmission Oil Cooler

from

$294.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

KAI – Radiator (Part No.RAD13116)

Radiator

from

$127.99
New Platinum Pro Radiator, 3.5 Liter Engine With Automatic Transmission, Without Tow Package, With A/C, USA/Japan Built Models

Product Features:
  • 3.5 Liter Engine With Automatic Transmission, Without Tow Package, With A/C, USA/Japan Built Models, Made Of Plastic and Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
See More

DENSO – First Time Fit Relay (Part No.P2020194560ND)

First Time Fit Relay

from

$25.84
An electrical relay is sort of a magical device: it takes a small electrical signal and uses it to manage a much more powerful current, permitting electrical systems to be both lighter and more dependable at the same time. DENSO has supplied quality relays to the OE automotive world for over 60 years. The very same performance and dependability are available across the replacement aftermarket with DENSO First Time Fit® relays. Engineered to meet the most stringent automaker standards for shock resistance, arcing, and thermal protection, DENSO auto relays feature the lowest return rates in the industry; that equals value for car owners and repair facilities alike

Product Features:
  • Lead-free, solderless construction prevents heat shock and arcing
  • Controlled contact force, self-adjusting air gap increase longevity of the internal parts
  • Industry-standard packaging and footprint
  • Low heat generation
  • Reduced electrical loads
  • Built to last
See More

Carquest Premium – Multi Purpose Relay (Part No.RAA2117)

Multi Purpose Relay

from

$17.79
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
See More

Sankei Switches – Engine Coolant Temperature Sensor (Part No.C6020243726SAK)

Engine Coolant Temperature Sensor

from

$33.13
The Sankei Switches Engine Coolant Temperature Sensor is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Carquest Premium – Coolant Temperature Sensor with O-Ring (Part No.WTC2071)

Coolant Temperature Sensor with O-Ring

from

$8.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
See More

Santech – Aux. Fan Control Uni (Part No.G5007755207SII)

Aux. Fan Control Uni

from

$199.49
Aux. Fan Control Uni

NPW – Water Pump (Part No.G3000848775NPW)

Water Pump

from

$137.16
Water Pump

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3130)

Engine Water Pump: New, Gasket/Seals Included

from

$134.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
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DENSO – New Compressor With Clutch (Part No.471-1575)

New Compressor With Clutch

from

$552.99
As one of the world’s largest OE suppliers of A/C compressors, DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO, we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors, you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO’s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:
  • DENSO is the world’s largest OE supplier of A/C compressors
  • Each compressor is precision manufactured for exact replacement
  • Designed for high output and extended durability
  • Highest quality in the Aftermarket
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Carquest Premium – A/C New, with Clutch, with 6SBU16C Compressor (Part No.T158336)

A/C New, with Clutch, with 6SBU16C Compressor

from

$349.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.

Product Features:
  • Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
  • New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
  • The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
  • All new compressors must pass a helium leak test and pump up function test prior to packaging.
  • O-Rings and gaskets necessary for installation are included.
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Dorman – Radiator Filler Neck (Part No.G1011719777DOR)

Radiator Filler Neck

from

$61.95
Re-engineered to address common failure points in the original equipment, Dorman’s Engine Coolant Filler Neck has improved durability and resistance. It withstands the extreme changes in temperature that frequently cause housing to become brittle, crack and leak. This is more than a replacement; it’s an upgrade. Maintain the steady flow of coolant and lessen the chances of overheating.

Product Features:
  • Direct replacement for a proper fit every time
  • Quality tested to ensure a trouble-free installation and conformance to product standards
  • High-quality plastic or metal construction
  • Includes all hardware necessary for a complete repair (where applicable)
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Carquest Premium – OUTLET FLANGE (Part No.CH2093)

OUTLET FLANGE

from

$74.99
OUTLET FLANGE

KAI – A/C Desiccant Element (Part No.ARD010152)

A/C Desiccant Element

from

$10.99
New Standard Replacement A/C Receiver Drier/Desiccant Element

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
See More

Carquest Premium – A/C Desiccant Bag Kit (Part No.T83233)

A/C Desiccant Bag Kit

from

$19.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:
  • All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
  • Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
  • All accumulators and receiver driers are helium leak tested prior to packaging.
  • O-Rings necessary for installation are included.
See More

Santech – Drier Desiccant Elem (Part No.R10432105970SII)

Drier Desiccant Elem

from

$20.54
Drier Desiccant Elem

DENSO – First Time Fit Drier Desiccant Element (Part No.R1043393863ND)

First Time Fit Drier Desiccant Element

from

$46.28
The Denso Drier Desiccant Element is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
See More

Upgrade your 2022 Lexus RX350 with Top-Quality Cooling and Climate Controls

When it comes to maintaining or upgrading your 2022 Lexus RX350, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Cooling and Climate Controls are key to keeping your RX350 functioning at its best. At Advance Auto Parts, we offer a wide selection of 19 Cooling and Climate Controls for the 2022 Lexus RX350, designed to meet your needs without breaking the bank. From Air Conditioning Part replacements to Engine Cooling Parts upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2022 Lexus RX350 at great prices. Our Cooling and Climate Controls inventory for this model ranges from just $8.99 to $465.99, with an average price of $151.72. Our 19 Cooling and Climate Controls in stock come from 8 trusted brands, so you’re sure to find the right part for your 2022 Lexus RX350 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2022 Lexus RX350, we stock popular OEM and aftermarket Cooling and Climate Controls from top names like Carquest Premium, and more. Carquest Premium Cooling and Climate Controls start at just $8.99 and boast an impressive 4 stars average rating from customers. With 276 customer reviews and counting, our 2022 Lexus RX350 Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2022 Lexus RX350 is always ready to roll. We’re committed to providing you with everything you need to keep your RX350 in top shape, all in one place. Start shopping confidently below for your 2022 Lexus RX350!

Best-Selling Air Conditioning Parts for 2022 Lexus RX350s

Enhance the driving experience in your Lexus with 6 quality Air Conditioning Part components, starting at $19.99.

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA1745)

A/C Refrigerant Pressure Sensor

from

$83.99
The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:
  • Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
  • Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
  • All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
  • All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging
See More

Carquest Premium – New Compressor with Clutch, Nippondenso 7SAS17C (Part No.T168348)

New Compressor with Clutch, Nippondenso 7SAS17C

from

$465.99
High quality OE replacement part with all components needed to complete the job.

Product Features:
  • Endurance tested the equivalent of 50k miles
  • Includes specific electrical connector to eliminate splicing
  • Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
  • For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
  • Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
See More

Carquest Premium – New Compressor (Part No.T168367)

New Compressor

from

$462.99
Carquest Premium A/C compressors are 100% new units that are manufactured to the highest quality to meet or exceed OE specifications.

Product Features:
  • Every unit is 100% function and leak tested
  • Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
  • Very low friction coating used on swash plate to improve durability
  • PTFE coated pistons improve performance and reduce wear
  • Rubber dampened clutch plate ensures smooth clutch engagement and reduces wear
  • Matched high-quality needle-roller bearing ensures low friction and high load capability
  • Limited Lifetime Warranty when following warranty requirements: Flush A/C System, replace accumulator/receiver dryer, replace orifice tube/expansion device, and filling with correct oil and refrigerant
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Carquest Standard – Reman Nippondenso 7SAS17C Compressor w/ Clutch (Part No.DW167348)

Reman Nippondenso 7SAS17C Compressor w/ Clutch

from

$219.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Carquest.

Product Features:
  • Remanufactured compressors are 100 percent tested to ensure compressor function and noise level meets or exceeds OE specifications
  • Remanufactured compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
  • Remanufactured compressors are individually vacuum and pressure tested to ensure no leaks
  • Remanufactured compressors come with the R12/R134A/1234yf required O-rings /sealing washers to install the compressor
  • Remanufactured Compressors are built in a ISO9001:2015 Certified facility to ensure consistent quality standards in the Re-manufacturing process
  • Remanufactured compressors are 100 percent tested to ensure compressor function and noise level meets or exceeds OE specifications
  • Remanufactured compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
  • Remanufactured compressors are individually vacuum and pressure tested to ensure no leaks
  • Remanufactured compressors come with the R12/R134A/1234yf required O-rings /sealing washers to install the compressor
  • Remanufactured Compressors are built in a ISO9001:2015 Certified facility to ensure consistent quality standards in the Re-manufacturing process
See More

Santech – A/C Pressure Switch (Part No.R1054261110SII)

A/C Pressure Switch

from

$44.70
A/C Pressure Switch

Carquest Premium – A/C Desiccant Bag Kit (Part No.T83233)

A/C Desiccant Bag Kit

from

$19.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:
  • All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
  • Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
  • All accumulators and receiver driers are helium leak tested prior to packaging.
  • O-Rings necessary for installation are included.
See More

Most Popular 2022 Lexus RX350 Engine Cooling Parts

Customize your Lexus with 10 Engine Cooling Parts products like Radiators, Water Pumps, and Thermostat and Water Outlet Assemblies, all priced under $259.99.

Sankei Switches – Sankei Switches Radiator Cap (Part No.G101045813SAK)

Sankei Switches Radiator Cap

from

$11.27
The Sankei Switches radiator cap range has been developed to operate within original equipment manufacturer’s specifications. A faulty radiator cap can cause your car to boil-over at a lower temperature. Test or replace the coolant cap when servicing the cooling system.

Product Features:
  • Meets Original Equipment specifications.
  • Made from premium materials.
  • Designed to function on open cooling systems and overflow reservoir type systems.
See More

Carquest Premium – Radiator Cap: 16 PSI (Part No.10242)

Radiator Cap: 16 PSI

from

$14.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

DENSO – First Time Fit Relay (Part No.P2020194560ND)

First Time Fit Relay

from

$25.84
An electrical relay is sort of a magical device: it takes a small electrical signal and uses it to manage a much more powerful current, permitting electrical systems to be both lighter and more dependable at the same time. DENSO has supplied quality relays to the OE automotive world for over 60 years. The very same performance and dependability are available across the replacement aftermarket with DENSO First Time Fit® relays. Engineered to meet the most stringent automaker standards for shock resistance, arcing, and thermal protection, DENSO auto relays feature the lowest return rates in the industry; that equals value for car owners and repair facilities alike

Product Features:
  • Lead-free, solderless construction prevents heat shock and arcing
  • Controlled contact force, self-adjusting air gap increase longevity of the internal parts
  • Industry-standard packaging and footprint
  • Low heat generation
  • Reduced electrical loads
  • Built to last
See More

Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 188 Degrees (Part No.1049-188)

Integrated Thermostat Housing: With Sensor, With Seal, 188 Degrees

from

$229.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813596)

Radiator: With Transmission Oil Cooler

from

$259.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Santech – Aux. Fan Control Uni (Part No.G5007755207SII)

Aux. Fan Control Uni

from

$199.49
Aux. Fan Control Uni

Dorman – Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees (Part No.902-5216)

Thermostat Assembly: Includes Housing and Thermostat, 189 Degrees

from

$162.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models.
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking.
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Aisan – Water Pump (Part No.G3000838456ASC)

Water Pump

from

$134.77
Water Pump

Carquest Premium – OUTLET FLANGE (Part No.CH2093)

OUTLET FLANGE

from

$74.99
OUTLET FLANGE

Carquest Premium – Coolant Temperature Sensor with O-Ring (Part No.WTC2071)

Coolant Temperature Sensor with O-Ring

from

$8.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Top Picks for 2022 Lexus RX350 HVAC Electrical Parts

Upgrade Lexus RX350s with top-quality HVAC Electrical Parts parts, including 1 OEM and aftermarket selections for your 2022 model.

DENSO – Cabin Air Temperatur (Part No.P4028815518ND)

Cabin Air Temperatur

from

$32.81
Cabin Air Temperatur

In-Demand Blower Motor and Related Products for 2022 Lexus RX350s

Select from 2 premium Blower Motor and Related Products parts for your 2022 Lexus RX350, with prices ranging from $123.99 to $304.99.

Carquest Premium – Blower Motor: With Wheel (Part No.76513)

Blower Motor: With Wheel

from

$304.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
  • Functionally Equivalent to OE Design
  • Magnetic size and properties compare or exceed OEM
  • Hermetically Sealed & Thermally Protected Electronics
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Carquest Premium – Blower Motor: With Wheel (Part No.75076)

Blower Motor: With Wheel

from

$123.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
See More

Top-Rated Cooling and Climate Controls Brands For Your 2022 Lexus RX350

Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2022 Lexus RX350s. Below you’ll find some of our best rated Cooling and Climate Controls from Carquest Premium, and more. Cooling and Climate Controls from these brands that fit a 2022 RX350 start at just $8.99 and are rated as high as 4 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.

Popular Carquest Premium 2022 Lexus RX350 Cooling and Climate Controls

When it comes to maintaining or upgrading your 2022 Lexus RX350, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. Carquest Premium ticks all of those boxes. We offer a wide selection of Carquest Premium Cooling and Climate Controls, specifically designed for the 2022 Lexus RX350. With over 10 Carquest Premium brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $8.99, with an average price of just $182.09. Plus, with over 137 customer reviews and an average rating of 4 stars, you can trust that our Carquest Premium Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

New Compressor with Clutch, Nippondenso 7SAS17C
from
$465.99
This product is not rated

New Compressor with Clutch, Nippondenso 7SAS17C

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A/C Refrigerant Pressure Sensor
from
$83.99
This product is not rated

A/C Refrigerant Pressure Sensor

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New Compressor
from
$462.99
This product is not rated

New Compressor

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FAQs for 2022 Lexus RX350 Cooling and Climate Controls

Which Cooling and Climate Controls are best-sellers for 2022 Lexus RX350s?

Out of 19 Cooling and Climate Controls that fit 2022 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2022 Lexus RX350 Cooling and Climate Controls?

Cooling and Climate Control prices for the 2022 Lexus RX350 start at $8.99 and go up to $465.99 for the most premium parts.

What’s the average price of a Cooling and Climate Control for a 2022 Lexus RX350?

The average price for Cooling and Climate Controls for the 2022 Lexus RX350 is $151.72. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Cooling and Climate Controls for other Lexus RX350 model years?

Yes, we currently carry Cooling and Climate Controls for 17 model years of Lexus RX350s between 2007 and 2024. Cooling and Climate Controls are bought most frequently for the following model years: 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Cooling and Climate Controls for my 2022 Lexus RX350?

The cheapest 2022 Lexus RX350 Cooling and Climate Controls we carry in stock are:

What are the top-rated Cooling and Climate Controls that fit the 2022 Lexus RX350?

Out of 276 reviews by customers, our 2022 Lexus RX350 Cooling and Climate Controls have an average customer rating of . These are some of the highest-rated Cooling and Climate Control types for the 2022 Lexus RX350 and their top-rated products:

Can I get help with 2022 Lexus RX350 Cooling and Climate Control orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Cooling and Climate Controls and more.

What is your return policy for Lexus RX350 Cooling and Climate Controls?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.