2021 GMC Sierra 3500 HD Cooling and Climate Controls

Essential 2021 GMC Sierra 3500 HD Cooling and Climate Controls

Carquest Premium – Universal Fan Clutch (Part No.216090)

Universal Fan Clutch

from

$493.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
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Felpro – Engine Water Pump Gasket (Part No.35635)

Engine Water Pump Gasket

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$6.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-111)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

from

$111.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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ACDelco – 12587397 GM Original Equipment Engine Coolant Water Inlet Seal (Part No.G4030310258ACD)

12587397 GM Original Equipment Engine Coolant Water Inlet Seal

from

$8.72
An ACDelco GM Original Equipment Engine Coolant Water Inlet Seal is a GM-recommended replacement for your vehicle’s original component. It seals and helps prevent coolant from leaking out of cooling system components. This original equipment engine coolant water inlet seal has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Seals and helps prevent coolant from leaking out of cooling system components to maintain the proper engine temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)

Air Conditioning System Valve Core

from

$10.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repair leaking A/C system, restore A/C function
  • Helps restore A/C Function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – Multi Purpose Relay (Part No.RAA1732)

Multi Purpose Relay

from

$36.49
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Dorman – Water Pump Outlet Pipe (Part No.626-661)

Water Pump Outlet Pipe

from

$82.99
This engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles. It is engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion..

Product Features:
  • Direct replacement – this engine coolant pipe is designed to match the fit and function of the original pipe on specified vehicles.
  • Ideal solution – engineered to help ensure leak-free coolant transfer when an original pipe has failed from heat or corrosion
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
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ACDelco – 15-10595 GM Original Equipment Engine Coolant Water Outlet (Part No.G4010349243ACD)

15-10595 GM Original Equipment Engine Coolant Water Outlet

from

$17.81
ACDelco GM Original Equipment Engine Coolant Water Outlets are housings that connect the radiator hoses to the engine, typically housing the engine coolant thermostat. For certain applications, the water outlet contains threaded holes or ports for sensors and switches. These original equipment engine coolant water outlets are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54218CD)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$16.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
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ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040468277ACD)

GM Original Equipment Expansion Tank Cap

from

$12.31
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.

Product Features:
  • Seal and maintain pressure on the cooling system for vehicle safety
  • Raise the boiling point of the engine coolant to maintain efficiency
  • Fit most models of GM vehicles for expanded coverage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Instrument Panel Air Duct Air Temperature Sensor (Part No.15-5632)

Instrument Panel Air Duct Air Temperature Sensor

from

$9.99
ACDelco GM Original Equipment HVAC Temperature Sensor is a GM-recommended replacement component for one or more of the following vehicle systems: hvac. This original equipment sensor will provide the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Cabin Air Temp Sen. (Part No.P4119578241ACD)

Cabin Air Temp Sen.

from

$87.86
Cabin Air Temp Sen.

Carquest Premium – Standard Thermostat: With Seal, 187 Degrees (Part No.15158)

Standard Thermostat: With Seal, 187 Degrees

from

$38.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Standard Thermostat: With Seal, 185 Degrees (Part No.14728)

Standard Thermostat: With Seal, 185 Degrees

from

$43.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Standard – Reman Nippondenso 10S20F Compressor w/ Clutch (Part No.DW77363)

Reman Nippondenso 10S20F Compressor w/ Clutch

from

$314.99
Carquest Standard compressors offer reliable, long-lasting performance for a leak-free, dependable repair.

Product Features:
  • Built in a TS16949 certified manufacturing environment to ensure consistent quality that meets or exceeds OE specifications for fit, form, function and durability
  • All remanufactured compressors are built using the latest compressor technology available today and using strict remanufacturing processes
  • All units have new seals, O-rings, gaskets and clutch bearings
  • Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
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DENSO – New Compressor With Clutch (Part No.471-0316)

New Compressor With Clutch

from

$419.99
As one of the world+s largest OE suppliers of A/C compressors DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO+s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:
  • DENSO is the world’s largest OE supplier of A/C compressors
  • Each compressor is precision manufactured for exact replacement
  • Designed for high output and extended durability
  • Highest quality in the Aftermarket
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Motorad – Coolant Housing/Water Outlet: (Part No.CH6007)

Coolant Housing/Water Outlet:

from

$78.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. The construction of this housing is improved over the OE design to fix and update any issues that the OE design may have had.

Product Features:
  • Easy, one step fit and installation
  • No special tools required
  • Meets or exceeds all OEM standards
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Dorman – Coolant Housing/Water Outlet: With Water Outlet, 90 Degree Neck Angle (Part No.902-2127)

Coolant Housing/Water Outlet: With Water Outlet, 90 Degree Neck Angle

from

$111.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
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Carquest Premium – Blower Motor: With Wheel (Part No.75876)

Blower Motor: With Wheel

from

$92.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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Carquest Premium – Blower Motor: With Wheel (Part No.76505)

Blower Motor: With Wheel

from

$129.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
  • Functionally Equivalent to OE Design
  • Magnetic size and properties compare or exceed OEM
  • Hermetically Sealed & Thermally Protected Electronics
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Carquest Premium – Coolant Housing/Water Outlet (Part No.85945)

Coolant Housing/Water Outlet

from

$20.99
We are proud to offer this CARQUEST product line: CARQUEST Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable)
  • 100% leak tested
  • Direct-fit replacement for ease of installation
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GM Genuine Parts – Water Inlet Seal (Part No.12587397)

Water Inlet Seal

from

$8.99
GM Genuine Parts Engine Coolant Thermostat Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help close and prevent coolant from leaking out of your vehicle’s cooling system components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps close and prevent coolant from leaking out of your vehicle’s cooling system components to maintain the proper engine temperature
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – Coolant Temperature Sensor (Part No.WTC1002)

Coolant Temperature Sensor

from

$20.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Carquest Premium – Coolant Temperature Sensor (Part No.WTC1022)

Coolant Temperature Sensor

from

$29.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Carquest Premium – Engine Coolant Temperature Sensor (Part No.FTA1002)

Engine Coolant Temperature Sensor

from

$62.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Delphi – Engine Coolant Temperature Sensor (Part No.TS10075)

Engine Coolant Temperature Sensor

from

$29.99
Delphi temperature sensors are built with the latest OE technology; Delphi temperature sensors use durable, one-piece design; Delphi temperature sensors are impervious to electrical noise and interference.

Product Features:
  • Delphi temperature sensors deliver accurate readings and optimal performance
  • Delphi’s one-piece design and automated production process eliminates internal connectors and failure points
  • Each sensor is electrically insulated to eliminate interference from other components in the vehicle
  • Delphi temperature sensors are impervious to electrical noise and interference
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NTK – Engine Coolant Temperature Sensor (Part No.EF0173)

Engine Coolant Temperature Sensor

from

$34.99
The Engine Coolant Temperature Sensor determines the exact temperature of the engine coolant by sending an analog signal to the ECM to censure proper air/fuel ratio along with proper operation of the cooling fan(s) and temperature gauge. The Engine Coolant Temperature Sensor may be located on the cylinder head, engine block, thermostat housing or intake manifold. Reasons for replacement include: check engine light illumination, erratic or no temperature gauge operation, erratic or no cooling fan operation, and engine overheating.

Product Features:
  • OE MATCHED: Wires and probe length match OE. Mounting clip(s) included where applicable
  • FASTER RESPONSE TIME: Thermal conductive grease inside brass housing increases sensor response time
  • THE NTK DIFFERENCE: Thread sealant/o-ring installed where applicable. Thermistor placement within the housing matches OE to ensure proper output. Proper thermal conductive grease to provide accurate temperature transfer to the thermistor
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Delphi – Engine Coolant Temperature Sensor (Part No.TS10253)

Engine Coolant Temperature Sensor

from

$32.99
Delphi temperature sensors are built with the latest OE technology; Delphi temperature sensors use durable, one-piece design; Delphi temperature sensors are impervious to electrical noise and interference.

Product Features:
  • Delphi temperature sensors deliver accurate readings and optimal performance
  • Delphi’s one-piece design and automated production process eliminates internal connectors and failure points
  • Each sensor is electrically insulated to eliminate interference from other components in the vehicle
  • Delphi temperature sensors are impervious to electrical noise and interference
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2021 GMC Sierra 3500 HD Cooling and Climate Controls

You count on your 2021 GMC Sierra 3500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 30 Cooling and Climate Controls ranging in price from $7.49 to $576.99, you’re sure to find everything you need for your 2021 GMC Sierra 3500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 7 different brands like Carquest Premium, Motorad, and Dorman. 2021 GMC Sierra 3500 HD Cooling and Climate Controls start as low as $7.49!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 415 extensive product reviews on 2021 GMC Sierra 3500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Air Conditioning System Valve Core with 5.0 stars and Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack with 5.0 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2021 GMC Sierra 3500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2021 GMC Sierra 3500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2021 GMC Sierra 3500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Motorad, Dorman, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Engine Cooling Parts. All are waiting to get your 2021 GMC Sierra 3500 HD back on the road. Some of the top-rated ACDelco products in these categories are:

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2021 GMC Sierra 3500 HD, and some of our most reviewed Carquest Premium parts include:
Standard Thermostat: With Seal, 187 Degrees
from $38.99
(45)
Standard Thermostat: With Seal, 187 Degrees
Thermostats
Standard Thermostat: With Seal, 180 Degrees
from $42.99
(7)
Standard Thermostat: With Seal, 180 Degrees
Thermostats
Standard Thermostat: With Seal, 185 Degrees
from $43.99
(7)
Standard Thermostat: With Seal, 185 Degrees
Thermostats

FAQs for 2021 GMC Sierra 3500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2021 GMC Sierra 3500 HD?

Out of 30 Cooling and Climate Controls for the 2021 GMC Sierra 3500 HD, the most popular in our inventory are:
Radiator Cap: 20 PSI
from $19.79
(6)
Radiator Cap: 20 PSI
Coolant Reservoir Caps
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
from $16.99
This product is not rated
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
Coolant Reservoir Caps

What are the top-rated 2021 GMC Sierra 3500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2021 GMC Sierra 3500 HD based on customer reviews/ratings are:
Air Conditioning System Valve Core
from $10.99
(6)
Air Conditioning System Valve Core
“Use it on my suv”
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
from $12.99
(1)
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
“Fits perfect”