2021 GMC Sierra 3500 HD Cooling and Climate Controls

Essential 2021 GMC Sierra 3500 HD Cooling and Climate Controls

ACDelco – 15-10595 GM Original Equipment Engine Coolant Water Outlet (Part No.G4010349243ACD)

15-10595 GM Original Equipment Engine Coolant Water Outlet

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$17.99
ACDelco GM Original Equipment Engine Coolant Water Outlets are housings that connect the radiator hoses to the engine, typically housing the engine coolant thermostat. For certain applications, the water outlet contains threaded holes or ports for sensors and switches. These original equipment engine coolant water outlets are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Felpro – Engine Water Pump Gasket (Part No.36109)

Engine Water Pump Gasket

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$19.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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ACDelco – A/C Service Valve (Part No.R1129578442ACD)

A/C Service Valve

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$10.18
A/C Service Valve

ACDelco – A/C Service Valve (Part No.R1129947779ACD)

A/C Service Valve

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$13.13
A/C Service Valve

Dorman – Coolant Bypass Tube O-Ring Kit (Part No.926-424)

Coolant Bypass Tube O-Ring Kit

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$19.29
This coolant O-ring kit contains all the necessary O-rings to replace or repair the engine coolant pipe on specified vehicles.

Product Features:
  • Ideal replacement – this coolant O-ring kit matches the factory O-rings to ensure a complete and reliable repair
  • Durable construction – made of quality materials for leak-free service
  • Complete solution – includes all O-rings required to repair or replace specified coolant pipe
  • Quality tested – this part has undergone try-on and material testing to ensure a quality fit and long service life
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Mahle – Intake Manifold Gasket Set (Part No.A8043948945MAH)

Intake Manifold Gasket Set

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$166.35
WARNING: This item cannot be returned for a replacement or refund if opened! Mahle is the largest gasket manufacturer in the world, providing you original equipment design and quality and world class aftermarket service. Mahle does not just cut gaskets – it designs total system sealing approaches that utilize application engineering. This means that regardless of what application you are trying to seal, you can count on Mahle doing the research and testing to provide the optimum material and technology for that specific application – this systems sealing approach requires a variety of materials. No other gasket manufacturer offers the Application Engineered approach to sealing an engine. A variety of different gasket materials insure an engine gets the optimal seal. All gaskets are not created equal – Mahle gaskets prove it every day.

Product Features:
  • Original equipment design and quality
  • Head sets give you original equipment form, fit, and function
  • Utilizes OE equivalent or better materials in all head sets
  • Packaged in shrink wrapped tray
  • Every part you need to complete your gasket repair in one package unless otherwise stated
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Carquest Standard – Reman Nippondenso 10SE18 Compressor w/ Clutch (Part No.DW197353)

Reman Nippondenso 10SE18 Compressor w/ Clutch

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$238.99
Carquest Standard compressors offer reliable, long-lasting performance for a leak-free, dependable repair.

Product Features:
  • Built in a TS16949 certified manufacturing environment to ensure consistent quality that meets or exceeds OE specifications for fit, form, function and durability
  • All remanufactured compressors are built using the latest compressor technology available today and using strict remanufacturing processes
  • All units have new seals, O-rings, gaskets and clutch bearings
  • Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
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KAI – A/C Compressor, Denso, V8 Engine (Part No.ACP010583)

A/C Compressor, Denso, V8 Engine

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$302.99
New Standard Replacement A/C Compressor, Denso, V8 Engine

Product Features:
  • Denso, V8 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – Coolant Housing/Water Outlet (Part No.85945)

Coolant Housing/Water Outlet

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$20.99
We are proud to offer this CARQUEST product line: CARQUEST Water Outlets. Our products are engineered and tested to provide years of trouble free operation and designed to be hassle free OE replacement part that meets and/or exceeds OE standards. Backed by over 50 years of mobile temperature control experience, fix it once and fix it right with CARQUST Water Outlets and Thermostat Housings.

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable)
  • 100% leak tested
  • Direct-fit replacement for ease of installation
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Motorad – Coolant Housing/Water Outlet: (Part No.CH6007)

Coolant Housing/Water Outlet:

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$78.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. The construction of this housing is improved over the OE design to fix and update any issues that the OE design may have had.

Product Features:
  • Easy, one step fit and installation
  • No special tools required
  • Meets or exceeds all OEM standards
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Carquest Premium – Universal Fan Clutch (Part No.216090)

Universal Fan Clutch

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$493.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
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Carquest Premium – Reverse Rotation Thermal Fan Clutch – Heavy Duty 7" (Part No.215107)

Reverse Rotation Thermal Fan Clutch - Heavy Duty 7"

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$92.99
Product Features:
  • Designed, tested, and built by application
  • OE performance, fit, and appearance
  • Precision machined
  • Out of box installation
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-106)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

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$116.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-525)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

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$121.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Carquest Premium – Blower Motor: With Wheel (Part No.75843)

Blower Motor: With Wheel

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$98.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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Carquest Premium – Blower Motor: With Wheel (Part No.75748)

Blower Motor: With Wheel

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$118.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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Carquest Premium – Radiator Cap Tester Adapter (Part No.12033)

Radiator Cap Tester Adapter

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$93.99
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
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Santech – A/C Service Valve Fi (Part No.R11491515863SII)

A/C Service Valve Fi

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$3.77
A/C Service Valve Fi

GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)

Air Conditioning System Valve Core

from

$10.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repair leaking A/C system, restore A/C function
  • Helps restore A/C Function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – Standard Thermostat: With Seal, 185 Degrees (Part No.14728)

Standard Thermostat: With Seal, 185 Degrees

from

$43.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000310418ACD)

GM Original Equipment Engine Coolant Thermostat

from

$62.94
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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NTK – Engine Coolant Temperature Sensor (Part No.EF0173)

Engine Coolant Temperature Sensor

from

$34.99
The Engine Coolant Temperature Sensor determines the exact temperature of the engine coolant by sending an analog signal to the ECM to censure proper air/fuel ratio along with proper operation of the cooling fan(s) and temperature gauge. The Engine Coolant Temperature Sensor may be located on the cylinder head, engine block, thermostat housing or intake manifold. Reasons for replacement include: check engine light illumination, erratic or no temperature gauge operation, erratic or no cooling fan operation, and engine overheating.

Product Features:
  • OE MATCHED: Wires and probe length match OE. Mounting clip(s) included where applicable
  • FASTER RESPONSE TIME: Thermal conductive grease inside brass housing increases sensor response time
  • THE NTK DIFFERENCE: Thread sealant/o-ring installed where applicable. Thermistor placement within the housing matches OE to ensure proper output. Proper thermal conductive grease to provide accurate temperature transfer to the thermistor
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Carquest Premium – Coolant Temperature Sensor (Part No.WTC1022)

Coolant Temperature Sensor

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$29.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Dorman – Help – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.54218CD)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$16.99
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
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ACDelco – GM Original Equipment Expansion Tank Cap (Part No.G1040465619ACD)

GM Original Equipment Expansion Tank Cap

from

$17.61
An ACDelco GM Original Equipment Expansion Tank Cap is a spring loaded cap that seals the radiator filler neck or surge tank, and is a GM-recommended replacement for your vehicle’s original component. It maintains pressure on the cooling system while the engine is operating, which raises the boiling point of the engine coolant. It also replenishes the system with coolant from the expansion tank (if equipped) when the engine cools off. This original equipment radiator cap has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors. Get the GM quality you know and trust with ACDelco GM Original Equipment Thermostats and Caps. Stay with the brand of parts your General Motors vehicle came with and get peace of mind that the fit, form, and function is up to the high standards and specifications of General Motors. ACDelco GM Original Equipment Thermostats and Caps are engineered for virtually every model of GM car, light duty truck, and sport utility vehicle.

Product Features:
  • Seal and maintain pressure on the cooling system for vehicle safety
  • Raise the boiling point of the engine coolant to maintain efficiency
  • Fit most models of GM vehicles for expanded coverage
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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2021 GMC Sierra 3500 HD Cooling and Climate Controls

You count on your 2021 GMC Sierra 3500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 26 Cooling and Climate Controls ranging in price from $7.49 to $576.99, you’re sure to find everything you need for your 2021 GMC Sierra 3500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 7 different brands like Carquest Premium, Motorad, and Dorman. 2021 GMC Sierra 3500 HD Cooling and Climate Controls start as low as $7.49!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 415 extensive product reviews on 2021 GMC Sierra 3500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Air Conditioning System Valve Core with 5.0 stars and Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack with 5.0 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2021 GMC Sierra 3500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2021 GMC Sierra 3500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2021 GMC Sierra 3500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Motorad, Dorman, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Engine Cooling Parts. All are waiting to get your 2021 GMC Sierra 3500 HD back on the road. Some of the top-rated ACDelco products in these categories are:

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2021 GMC Sierra 3500 HD, and some of our most reviewed Carquest Premium parts include:
Standard Thermostat: With Seal, 187 Degrees
from $38.99
(45)
Standard Thermostat: With Seal, 187 Degrees
Thermostats
Standard Thermostat: With Seal, 180 Degrees
from $42.99
(7)
Standard Thermostat: With Seal, 180 Degrees
Thermostats
Standard Thermostat: With Seal, 185 Degrees
from $43.99
(7)
Standard Thermostat: With Seal, 185 Degrees
Thermostats

FAQs for 2021 GMC Sierra 3500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2021 GMC Sierra 3500 HD?

Out of 26 Cooling and Climate Controls for the 2021 GMC Sierra 3500 HD, the most popular in our inventory are:
Radiator Cap: 20 PSI
from $19.79
(6)
Radiator Cap: 20 PSI
Coolant Reservoir Caps
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
from $16.99
This product is not rated
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
Coolant Reservoir Caps

What are the top-rated 2021 GMC Sierra 3500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2021 GMC Sierra 3500 HD based on customer reviews/ratings are:
Air Conditioning System Valve Core
from $10.99
(6)
Air Conditioning System Valve Core
“Use it on my suv”
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
from $12.99
(1)
Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack
“Fits perfect”