2021 Ford F-550 Super Duty Engine Cooling Parts

Keep Your 2021 Ford F-550 Super Duty in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2021 Ford F-550 Super Duty looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Water Pumps, Thermostat and Water Outlet Gaskets, and Thermostat and Water Outlet Assemblies. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like FELPRO. For example, FELPRO Engine Cooling Parts start at just $10.99 with an average 4.6 star rating. With over 372 reviews and a solid 4 star average, you can shop with confidence knowing other Ford F-550 Super Duty owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2021 Ford F-550 Super Duty Engine Cooling Part at Advance Auto Parts is around $213.03, with a range that starts at $2.99 and goes up to $2,150.99. With 12 options in stock from 5 trusted brands, finding the right fit is easy. Popular picks like Engine Coolant Reservoir Cap, Standard Thermostat: With Seal, 194, 201 Degrees, and Engine Water Pump: New, Gasket/Seals Included start at just $22.99 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Blend Doors and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2021 Ford F-550 Super Duty in peak condition, inside and out.

Essential 2021 Ford F-550 Super Duty Engine Cooling Parts

Carquest Premium – Coolant Temperature Sensor 1TS1488 (Part No.WTA2354)

Coolant Temperature Sensor 1TS1488

from

$8.99
Carquest Premium coolant temperature sensors and switches are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry, Carquest Premium coolant temperature sensors and switches undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium coolant temperature sensors and switches are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:


    Product Features:
    • Designed to meet or exceed OE specifications for fit, form and function
    • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
    • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
    • O-rings, seals or thread sealant are included if required
    • Weather-tight connectors prevent leaks and corrosion for longer life
    • Extensive design validation testing and 100% end-of-line tested
    • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Motorcraft – Original Equipment (O.E.) Sender Assembly (Part No.DY-1194)

Original Equipment (O.E.) Sender Assembly

from

$51.99
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

Product Features:
  • Motorcraft and Ford Parts are used throughout Ford vehicles in a variety of applications that help ensure the proper build quality, integrity and long-lasting performance of every Ford car or truck.
  • Motorcraft and Ford Parts are manufactured from first-quality materials – chosen specifically for maximum performance and application suitability.
  • As with all Motorcraft and Ford Parts, any innovations or improvements developed since the vehicle’s manufacture are included in these after market replacement parts, ensuring the most current technology and performance.
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NTK – Engine Coolant Temperature Sensor (Part No.EF0106)

Engine Coolant Temperature Sensor

from

$31.99
The Engine Coolant Temperature Sensor determines the exact temperature of the engine coolant by sending an analog signal to the ECM to ensure proper air/fuel ratio along with proper operation of the cooling fans and temperature gauge. The Engine Coolant Temperature Sensor may be located on the cylinder head, engine block, thermostat housing or intake manifold. Reasons for replacement include, check engine light illumination, erratic or no temperature gauge operation, erratic or no cooling fan operation, and engine overheating.

Product Features:
  • OE MATCHED: Wires and probe length match OE. Mounting clips included where applicable
  • FASTER RESPONSE TIME: Thermal conductive grease inside brass housing increases sensor response time
  • THE DIFFERENCE: Thread sealant/o-ring installed where applicable. Thermistor placement within the housing matches OE to ensure proper output. Proper thermal conductive grease to provide accurate temperature transfer to the thermistor
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Carquest Premium – Radiator Cap: 20 PSI (Part No.10267)

Radiator Cap: 20 PSI

from

$21.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Carquest Premium – Engine Coolant Reservoir Cap (Part No.10262)

Engine Coolant Reservoir Cap

from

$22.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Carquest Premium – Engine Coolant Reservoir Cap (Part No.10240)

Engine Coolant Reservoir Cap

from

$5.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Carquest Premium – Standard Thermostat: With Seal, 194, 201 Degrees (Part No.49240)

Standard Thermostat: With Seal, 194, 201 Degrees

from

$59.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Standard Thermostat: 180 Degrees (Part No.13778)

Standard Thermostat: 180 Degrees

from

$15.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Motorad UltraStats – Thermostat: 192 Degrees (Part No.5378-192)

Thermostat: 192 Degrees

from

$36.99
UltraStat Thermostats are the toughest thermostats on the market. All heavy gauge stainless steel construction provides long-life durability, as well as complete corrosion resitance. Exclusive BLVT Valve technology minimizes thermal shock to cooling system components.

Product Features:
  • Heavy gauge stainless steel components offer increased reliability and long-lasting durability
  • Exclusive BLVT Valve Technology minimizes thermal shock to cooling system components
  • Stainless steel thermal element for unmatched corrosion resistance and revolutionary REAX wax mixture provides quicker reaction time
  • AccuSpring Design for stable temperature control and increased cabin comfort
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Felpro – Engine Water Pump Gasket (Part No.35478)

Engine Water Pump Gasket

from

$7.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Victor Reinz – Engine Water Pump Gasket (Part No.71-14046-00)

Engine Water Pump Gasket

from

$3.99
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
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Felpro – Engine Water Pump Gasket (Part No.35612)

Engine Water Pump Gasket

from

$10.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35610-1)

Engine Coolant Thermostat Housing Gasket

from

$6.49
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
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Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35702)

Engine Coolant Thermostat Housing Gasket

from

$4.79
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
See More

Felpro – Multi-Purpose O-Ring (Part No.35489)

Multi-Purpose O-Ring

from

$10.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Carquest Premium – Engine Coolant Integrated Thermostat Housing (Part No.85691)

Engine Coolant Integrated Thermostat Housing

from

$45.49
High quality OE replacement part with all components needed to complete the job.

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring  to ensure proper seal (where applicable)
  • Includes quality gasket or O-ringá to ensure proper seal (where applicable)
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • All-in-one bolt on solution for a complete repair
  • Includes quality thermostat
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring to ensure proper seal (where applicable)
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • All-in-one bolt on solution for a complete repair
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Dorman – Coolant Housing/Water Outlet: with Housing (Part No.902-759)

Coolant Housing/Water Outlet: with Housing

from

$47.99
This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings
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Motorcraft – THERMOSTAT HOUSING (Part No.RH-63)

THERMOSTAT HOUSING

from

$48.99
THERMOSTAT HOUSING

Motorad – Thermostat Housing Assembly: Includes Stat, Sensor, Seals, 194 and 201 Degrees (Part No.TA1074)

Thermostat Housing Assembly: Includes Stat, Sensor, Seals, 194 and 201 Degrees

from

$1878.00
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14899)

Integrated Thermostat Housing: With Seal, 192 Degrees

from

$30.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Motorad – Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 192 Degrees (Part No.5190KT)

Engine Coolant Thermostat Housing Assembly Thermostat: With Seal, 192 Degrees

from

$44.99
Kit includes thermostat, housing, and all necessary seals/gaskets to do the complete job. These individual parts are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat and housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
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Dorman – Help – Upper and Lower Coolant Hose Seal (OE Fix) (Part No.47450)

Upper and Lower Coolant Hose Seal (OE Fix)

from

$18.49
Certain Ford vehicles use radiator hoses that employ a connection sealed with an O-ring. Through age, heat cycling and normal wear and tear, the O-ring can deform or become damaged to the point where it no longer seals effectively. The dealer sells the O-rings only as part of the complete hose assembly. This OE FIX engine coolant pipe O-ring kit is designed to reduce repair expense while matching the performance of the original part on specified vehicles. The O-ring helps to prevent coolant leaks and should be replaced periodically or if the connection is disturbed during service. This kit is made with quality materials and is engineered for reliable performance and durability.

Product Features:
  • Direct replacement – this OE FIX coolant pipe O-ring kit is designed to help restore proper cooling system function and prevent coolant leaks on specified vehicles
  • Cost-conscious repair – replacing just the sealing components instead of the complete hose keeps properly-functioning parts in service
  • Durable construction – designed and manufactured to strict specifications for reliable performance
  • Trustworthy quality – backed by a team of product experts in the United States and more than a century of automotive experience
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Dorman – Coolant Tee and Radiator Hose O-Ring Kit (OE Fix) (Part No.926-168)

Coolant Tee and Radiator Hose O-Ring Kit (OE Fix)

from

$30.99
When the seals fail between an upper coolant tee and radiator hose, there typically hasn’t been a fix besides buying a whole new coolant tee. This Dorman OE FIX kit offers a cost effective direct replacement of worn O-rings.

Product Features:
  • Cost-effective repair – this kit allows you to directly replace coolant tee and radiator hose O-rings
  • Complete set – includes two large and one small O-ring
  • Application specific – strictly designed for certain Ford F150 and Mustang model years
  • Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience
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Motorcraft – THERMOSTAT O-RING (Part No.RG-571)

THERMOSTAT O-RING

from

$2.99
THERMOSTAT O-RING

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T1305)

Engine Water Pump: New, Gasket/Seals Included

from

$231.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T5094)

Engine Water Pump: New, Gasket/Seals Included

from

$164.99
Carquest Premium drive motor inverter cooler water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
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Driveworks Water Pumps – Water Pump – Domestic Reman (Part No.58-554)

Water Pump - Domestic Reman

from

$108.99
100% leak testing And hub-pull testing ensures reliable performance. O.E.-supplied NEW unitized seals ensure long-lasting, trouble-free performance. Unlike other aftermarket manufacturers, CARDONE installs the proper O.E. specified bearing design to meet the specific radial And axial load requirements of each application. This ensures longer bearing life And reliable performance. Original casting specifications are strictly followed to ensure proper fit for easy installation And proper water flow for maximum cooling.

Product Features:
  • 100% leak testing and hub-pull testing ensures reliable performance.
  • O.E.-supplied NEW unitized seals ensure long-lasting, trouble-free performance.
  • The proper O.E. specified bearing design is installed to meet the specific radial and axial load requirements of each application. This ensures longer bearing life and reliable performance.
  • Thermostat seal and mounting gasket are supplied for ease of installation (where applicable).
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Driveworks Water Pumps – Water Pump: New, Installation Gasket Included (Part No.58-597)

Water Pump: New, Installation Gasket Included

from

$101.99
Driveworks Water Pumps offer a complete replacement part solution, with application coverage that spans from antique to present-day vehicles. All units are 100% tested and engineered to meet or exceed OEM performance, providing you a quality product you and your vehicle can rely on. All units are manufacturered with brand new components and are packaged with all gaskets required for replacement.

Product Features:
  • 100% Factory tested for leakage and dimensional precision
  • Manufactured to original casting specifications to ensure a proper fit and proper water flow for efficient cooling
  • Bearings made of heat-treated carbon or carburized steel are sealed and lubricated to ensure smooth performance throughout units life
  • Assembled with new, high-quality unitized shaft seals to prevent premature leakage
  • Supplied with gasket and other seals/gaskets as applicable per application to help complete the job
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
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Most Popular Water Pump for 2021 Ford F-550 Super Duties

Enhance your 2021 Ford F-550 Super Duty with this popular Water Pump we have in stock, for $231.99.

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T1305)

Engine Water Pump: New, Gasket/Seals Included

from

$231.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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Best-Selling 2021 Ford F-550 Super Duty Thermostat and Water Outlet Gasket

Upgrade your F-550 Super Duty with our best-selling Thermostat and Water Outlet Gasket with a 4.5 Starts rating across 110 reviews.

Felpro – Multi-Purpose O-Ring (Part No.35489)

Multi-Purpose O-Ring

from

$10.99
Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
See More

Top-Quality Thermostat and Water Outlet Assemblies for 2021 Ford F-550 Super Duties

Choose a high-quality OEM or aftermarket Thermostat and Water Outlet Assembly for Ford F-550 Super Duties and enjoy top-notch performance from $2,150.99.

Motorad – Thermostat Housing Assembly – 194 & 201 Degrees (Part No.TA1061)

Thermostat Housing Assembly - 194 & 201 Degrees

from

$2150.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Top Picks for 2021 Ford F-550 Super Duty Thermostats

Invest in one of our 3 durable Thermostats for your 2021 Ford, knowing you’re getting trusted brands and expert craftsmanship.

Carquest Premium – Standard Thermostat: With Seal, 194, 201 Degrees (Part No.49240)

Standard Thermostat: With Seal, 194, 201 Degrees

from

$59.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: With Seal, 160 Degrees, 170 Degrees (Part No.717-160)

Standard Thermostat: With Seal, 160 Degrees, 170 Degrees

from

$84.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Standard Thermostat: With Seal, 192 Degrees (Part No.1121-192)

Standard Thermostat: With Seal, 192 Degrees

from

$62.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Our Top-Rated Coolant Reservoir Caps for 2021 Ford F-550 Super Duties

Make a smart move for your 2021 Ford F-550 Super Duty with our Coolant Reservoir Cap for $22.99.

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10262)

Engine Coolant Reservoir Cap

from

$22.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Top-Rated Engine Cooling Part Brands For Your 2021 Ford F-550 Super Duty

When it comes to finding the perfect Engine Cooling Part for your 2021 Ford F-550 Super Duty, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 5 trusted brands. We carry the most popular Engine Cooling Part brands including FELPRO, and more, all known for their exceptional customer ratings (average brand rating of 4.6 stars) and competitive prices, as low as $10.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2021 Ford F-550 Super Duty, providing peace of mind with parts that meet or exceed OEM standards.

Popular FELPRO 2021 Ford F-550 Super Duty Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2021 Ford F-550 Super Duty, Advance Auto Parts has exactly what you need with our selection of FELPRO Engine Cooling Parts. We have 1 FELPRO Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $10.99, you’ll find the perfect Engine Cooling Part for your needs and budget. FELPRO Engine Cooling Parts for the 2021 Ford F-550 Super Duty come highly rated, with over 110 customer reviews and an impressive average rating of 4.6 stars. Choosing a FELPRO Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Multi-Purpose O-Ring
from $10.99
(110)
Multi-Purpose O-Ring
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FAQs for 2021 Ford F-550 Super Duty Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2021 Ford F-550 Super Duties?

Out of 12 Engine Cooling Parts that fit 2021 Ford F-550 Super Duties, the following parts are the top sellers:

What’s the price range for 2021 Ford F-550 Super Duty Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2021 Ford F-550 Super Duty range from $2.99 up to $2,150.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2021 Ford F-550 Super Duty?

The average price for Engine Cooling Parts for the 2021 Ford F-550 Super Duty is $213.03. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Ford F-550 Super Duty model years?

Yes, we carry Engine Cooling Parts for 25 model years of Ford F-550 Super Duties between 1999 and 2025. The following model years are the most popular for Engine Cooling Part purchases: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Engine Cooling Parts for my 2021 Ford F-550 Super Duty?

The cheapest 2021 Ford F-550 Super Duty Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2021 Ford models?

Yes. We stock Engine Cooling Parts for 23 other popular 2021 Ford models. Some of the most popular are 2021 F-150 Engine Cooling Parts, 2021 Mustang Engine Cooling Parts, 2021 Explorer Engine Cooling Parts, 2021 Bronco Engine Cooling Parts, and 2021 F-250 Super Duty Engine Cooling Parts.

What are the top-rated Engine Cooling Parts that fit the 2021 Ford F-550 Super Duty?

The one 2021 Ford F-550 Super Duty Engine Cooling Part we have in stock is the THERMOSTAT O-RING. It costs $2.99.

What types of Engine Cooling Parts do you sell for my 2021 Ford F-550 Super Duty?

As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2021 Ford F-550 Super Duty:

Can I get help with 2021 Ford F-550 Super Duty Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Engine Cooling Parts and more.

What is your return policy for Ford F-550 Super Duty Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Ford F-550 Super Duty Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.