2021 Ford F-450 Super Duty Cooling and Climate Controls

Name: Integrated Thermostat Housing: With Seal, 192 Degrees
Brand: Carquest Premium
SKU: 14899
Price: 30.49 USD
Rating: 4.5 (9 reviews)

Below you will find various in-demand Ford Cooling and Climate Controls, components and accessories for your 2021 F-450 Super Duty. Advance Auto Parts has popular F-450 Super Duty parts like Heating Parts, Engine Cooling Parts, Air Conditioning Parts and more. You’ll also find aftermarket and OEM Cooling and Climate Controls for other F-450 Super Duty model years including 2013, 2014, 2015, 2016, 2017, 2018, 2019, 2020, 2022 and more. Select a category of 2021 Ford F-450 Super Duty Cooling and Climate Controls below and start saving instantly.

Popular 2021 Ford F-450 Super Duty Cooling and Climate Controls Categories

Thermostat and Water Outlet Assemblies

Air Blend Door Actuators

Coolant Temperature Sensors

Heater Cores

Coolant Reservoir Caps

Engine Coolant Pipe O-Rings

AC Caps and Valve Core Kits

Thermostat Housings

Thermostat and Water Outlet Gaskets

Water Pump Gaskets

Expansion Valve and Orifice Tubes

AC Refrigerant Pressure Sensors

AC Service Valve Caps

AC Receiver or Drier

Essential Cooling and Climate Controls for 2021 Ford F-450 Super Duties

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$30.49

Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

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$17.99

Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This thermostat will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$30.99

When the seals fail between an upper coolant tee and radiator hose, there typically hasn’t been a fix besides buying a whole new coolant tee. This Dorman OE FIX kit offers a cost effective direct replacement of worn O-rings.

Product Features:

Cost-effective repair – this kit allows you to directly replace coolant tee and radiator hose O-rings
Complete set – includes two large and one small O-ring
Application specific – strictly designed for certain Ford F150 and Mustang model years
Quality engineering – designed in the United States and backed by decades of automotive aftermarket experience

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$10.99

Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

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$6.49

Fel-Pro gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:

Meets or exceeds all original equipment specifications
Application specific design to ensure a perfect fit
Engineered and manufactured specifically for the repair environment
Unsurpassed quality you can trust
Validated for fit, form, and function

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$31.99

Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:

All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
All accumulators and receiver driers are helium leak tested prior to packaging.
O-Rings necessary for installation are included.

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$7.99

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

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$4.99

Carquest Orifice Tubes are designed to regulate the flow of refrigerant through the air conditioning system to provide optimal cooling to the passenger compartment. Each orifice tube is manufactured to original equipment specifications to perform its function even in the harshest climates. Each part is supplied with the necessary gaskets and o-rings for installation.

Product Features:

Each orifice tube is tested for function and leakage according to OEM specifications to ensure optimal performance of the air conditioning system.
O-Rings necessary for installation are included.
Color coded

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$337.99

Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:

Thermal tested under real-life temperature simulations
High tensile strength aluminum for maximum crimp strength
Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
OEM grade, premium fittings for transmission or engine oil coolers (where applicable)

from

$391.99

Thermal tested under real-life temperature simulations
High tensile strength aluminum for maximum crimp strength
Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
Oil cooler designs meet or exceed OE standards, keeping the vehicle¿s engine and transmission performing at optimal conditions
OEM grade, premium fittings for transmission or engine oil coolers (where applicable)

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$155.99

Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:

100% tested for reliable performance
Durable housing features precisely machined mounting surface for proper sealing and fitment
Equipped with weep chamber or similar feature to help prevent unnecessary replacement
Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
All gaskets or seals necessary for water pump are included
This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components

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$101.99

Driveworks Water Pumps offer a complete replacement part solution, with application coverage that spans from antique to present-day vehicles. All units are 100% tested and engineered to meet or exceed OEM performance, providing you a quality product you and your vehicle can rely on. All units are manufacturered with brand new components and are packaged with all gaskets required for replacement.

Product Features:

100% Factory tested for leakage and dimensional precision
Manufactured to original casting specifications to ensure a proper fit and proper water flow for efficient cooling
Bearings made of heat-treated carbon or carburized steel are sealed and lubricated to ensure smooth performance throughout units life
Assembled with new, high-quality unitized shaft seals to prevent premature leakage
Supplied with gasket and other seals/gaskets as applicable per application to help complete the job
This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation

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$39.99

The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging

from

$40.49

This replacement engine coolant thermostat housing is engineered to match the fit and durability of the stock thermostat housing on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:

Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings

from

$68.99

Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings

from

$67.99

New Standard Replacement Front Heater Core, Replaces Copper/Brass Unit

Product Features:

Replaces Copper/Brass Unit, Made Of Aluminum
Meets All Federal Motor Safety Standards
No Drilling Needed For Installation
No Modifications Needed For Installation
Direct Fit Replacement For Your Vehicle
Same Form Fit And Function As OE
Check Out The Large Selection Of Parts Available For Your Vehicle

from

$76.99

Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications. Carquest Premium provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability. Carquest Premium offers certified heater cores that meet or exceed OE specifications and are all fitment checked in the actual vehicle’s HVAC heater module and are, thus, ready to be installed right out of the box for a “Drop-In Fit”. Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.

Product Features:

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

from

$26.49

This air door actuator directly replaces the original actuator on specific vehicle years, makes, models, configurations and positions to restore proper HVAC operation. Please note that many vehicles have several different air door actuators, which are designed for specific positions and functions in the vehicle. To ensure you have what you need, carefully review the application notes for this part to verify it matches the position and function of the actuator you need to replace. In some online ordering systems, you may need to enter your vehicle information first to see the application notes for your vehicle. If you don’t know which actuator position you need to replace, consult a qualified service technician.

Product Features:

Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience

from

$83.99

BLEND DOOR ACTUATOR

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$203.99

Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Functionally Equivalent to OE Design
Magnetic size and properties compare or exceed OEM
Hermetically Sealed & Thermally Protected Electronics

from

$73.99

The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles. Motorcraft Parts are used throughout Ford vehicles in a variety of applications that help ensure the proper build quality, integrity and long-lasting performance of every Ford car or truck. Motorcraft Parts are manufactured from first quality materials chosen specifically for maximum performance and application suitability. As with all Motorcraft Parts, any innovations or improvements developed since the vehicle’s manufacture are included in these after market replacement parts, ensuring the most current technology and performance.

Product Features:

Same parts that came on the vehicle from the factory.
Permanently lubricated bearings for long life and quiet operation.
Quietly and efficiently moves air needed for heat, ventilation and air conditioning.
Application specific for easy installation.
Tested to ensure quiet operation at a variety of temperature/humidity conditions.
EMC testing ensures compatibility with other vehicle electrical systems.
The only parts recommended by Ford Motor Company for Ford, Lincoln and Mercury vehicles.

from

$16.99

Product Features:

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

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$55.99

Delphi’s history is one of OE heritage and quality. Our global technical requirements include design specifications and validation testing based on over 100 years of OE experience. Our material selections, material thickness, and material types are built from OE specifications to exceed aftermarket expectations. We put in place strict manufacturing processes to ensure quality control in every part we make. Delphi’s pioneering spirit delivers innovative solutions designed to support the aftermarket in servicing the vehicles of today, and tomorrow.

Product Features:

Delphi temperature sensors deliver accurate readings and optimal performance
Delphi’s one-piece design and automated production process eliminates internal connectors and failure points
Each sensor is electrically insulated to eliminate interference from other components in the vehicle
Delphi temperature sensors are impervious to electrical noise and interference

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$16.99

New Standard Replacement A/C System Valve Core And Cap Kit

Product Features:

Meets All Federal Motor Safety Standards
No Drilling Needed For Installation
No Modifications Needed For Installation
Direct Fit Replacement For Your Vehicle
Same Form Fit And Function As OE
Check Out The Large Selection Of Parts Available For Your Vehicle

from

$21.99

Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Factory Air.

Product Features:

All the seals needed to complete the job
Compatible with both R12 and R134a refrigerants
SUV and rear air applications
Application specific
All the seals needed to complete the job
Compatible with both R12 and R134a refrigerants
SUV and rear air applications
Application specific

from

$9.99

This A/C service valve cap is designed to match the fit and function of the original cap on specified applications, and is engineered for reliable performance and durability.

Product Features:

Direct replacement – this A/C service valve cap is designed to match the fit and function of the original cap on specified applications
Restores functionality – reliable replacement for an original part that is leaking or has failed due to fatigue
Durable construction – this part is made from quality materials to ensure reliable performance and long service life
Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience

Upgrade your 2021 Ford F-450 Super Duty with Top-Quality Cooling and Climate Controls

When it comes to maintaining or upgrading your 2021 Ford F-450 Super Duty, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Ford or enhancing its overall performance, Cooling and Climate Controls are key to keeping your F-450 Super Duty functioning at its best. At Advance Auto Parts, we offer a wide selection of 25 Cooling and Climate Controls for the 2021 Ford F-450 Super Duty, designed to meet your needs without breaking the bank. From Heating Part replacements to Engine Cooling Parts upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2021 Ford F-450 Super Duty at great prices. Our Cooling and Climate Controls inventory for this model ranges from just $2.99 to $2,150.99, with an average price of $147.87. Our 25 Cooling and Climate Controls in stock come from 5 trusted brands, so you’re sure to find the right part for your 2021 Ford F-450 Super Duty without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2021 Ford F-450 Super Duty, we stock popular OEM and aftermarket Cooling and Climate Controls from top names like FELPRO, and more. FELPRO Cooling and Climate Controls start at just $10.99 and boast an impressive 4.6 stars average rating from customers. With 426 customer reviews and counting, our 2021 Ford F-450 Super Duty Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Batteries and Chargers, Oil and Lubricants and more to make sure your 2021 Ford F-450 Super Duty is always ready to roll. We’re committed to providing you with everything you need to keep your F-450 Super Duty in top shape, all in one place. Start shopping confidently below for your 2021 Ford F-450 Super Duty!

Best-Selling Heating Parts for 2021 Ford F-450 Super Duties

Enhance the driving experience in your Ford with 2 quality Heating Part components, starting at $76.99.

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from

$76.99

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

from

$93.99

All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts

Most Popular 2021 Ford F-450 Super Duty Engine Cooling Parts

Customize your Ford with 13 Engine Cooling Parts products like Thermostats, Radiators, and Water Pumps, all priced under $2,150.99.

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from

$10.99

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

from

$22.99

Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:

Maintains proper cooling system pressure
Easy installation and removal
100% tested to ensure proper pressure and longevity
Meets all OEM specifications

from

$59.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$231.99

100% tested for reliable performance
Durable housing features precisely machined mounting surface for proper sealing and fitment
Equipped with weep chamber or similar feature to help prevent unnecessary replacement
Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
All gaskets or seals necessary for water pump are included
This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components

from

$40.49

Ideal replacement – this engine coolant thermostat housing directly replaces the original housing on specified vehicle years, makes and models
Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housings

from

$2150.99

Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant.

Product Features:

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$583.99

Thermal tested under real-life temperature simulations
High tensile strength aluminum for maximum crimp strength
Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles

from

$84.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$62.99

High grade stainless steel and copper construction
Meets or exceeds OEM standards
Consistent and precise response to cooling system needs
Original equipment design for worry-free direct fit replacement
100% tested and calibrated

from

$37.99

Manufactured to the highest OEM quality standards by an OE Supplier, using proprietary material to stand up to even the most demanding automotive cooling systems. Thermal shock validated and 100% leak tested.

Product Features:

Easy, one step fit and installation
No special tools required
Meets or exceeds all OEM standards

from

$30.99

Meets or exceeds all original equipment specifications
Application specific design
Manufactured for the sealing repair environment
Validated for fit, form, and function
Quality that you can trust

from

$8.99

Carquest Premium coolant temperature sensors and switches are designed to perform in harsh engine environments and meet or exceed original equipment (O.E.) specifications. Built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry, Carquest Premium coolant temperature sensors and switches undergo extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium coolant temperature sensors and switches are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:

Product Features:

Designed to meet or exceed OE specifications for fit, form and function
100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
O-rings, seals or thread sealant are included if required
Weather-tight connectors prevent leaks and corrosion for longer life
Extensive design validation testing and 100% end-of-line tested
Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413

from

$2.99

THERMOSTAT O-RING

Top Picks for 2021 Ford F-450 Super Duty Air Conditioning Parts

Upgrade Ford F-450 Super Duties with top-quality Air Conditioning Parts parts, including 5 OEM and aftermarket selections for your 2021 model.

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from

$73.99

Carquest Expansion Valves are designed to regulate the flow of refrigerant through the air conditioning system to provide optimal cooling to the passenger compartment. Each expansion valve is manufactured to original equipment specifications to perform its function even in the harshest climates. Each part is supplied with the necessary gaskets and o-rings for installation.

Product Features:

The bodies of these expansion valves are machined from a single block of aluminum or brass metal.
Each expansion valve has settings for tonnage and superheat based on the vehicle specifications.
Each expansion valve is tested for function and leakage according to OEM specifications to ensure optimal performance of the air conditioning system.
O-Rings necessary for installation are included.

from

$39.99

Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging

from

$20.49

All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
All accumulators and receiver driers are helium leak tested prior to packaging.
O-Rings necessary for installation are included.
O-Rings necessary for installation are included.

from

$4.99

A/C SERVICE VALVE

from

$4.99

Product Features:

Color: Black
Size: M8 x 1mm

In-Demand Blend Doors for 2021 Ford F-450 Super Duties

Select from 3 premium Blend Doors parts for your 2021 Ford F-450 Super Duty, with prices ranging from $26.49 to $26.99.

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from

$26.49

Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience

from

$26.49

Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience

from

$26.99

Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience

Most Sold 2021 Ford F-450 Super Duty Blower Motor and Related Products

Explore our best-selling Ford parts for the 2021 F-450 Super Duty among 2 OEM and aftermarket options starting from $203.99.

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from

$203.99

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor

from

$203.99

Meets or exceeds OE design and performance
Magnetic size and properties compare or exceed OEM
Windings meet or exceed OEM specifications
Motor RPM equivalent to or exceeds OEM motor
Functionally Equivalent to OE Design
Magnetic size and properties compare or exceed OEM
Hermetically Sealed & Thermally Protected Electronics

Top-Rated Cooling and Climate Controls Brands For Your 2021 Ford F-450 Super Duty

Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2021 Ford F-450 Super Duties. Below you’ll find some of our best rated Cooling and Climate Controls from FELPRO, and more. Cooling and Climate Controls from these brands that fit a 2021 F-450 Super Duty start at just $10.99 and are rated as high as 4.6 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.

Popular FELPRO 2021 Ford F-450 Super Duty Cooling and Climate Controls

When it comes to maintaining or upgrading your 2021 Ford F-450 Super Duty, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. FELPRO ticks all of those boxes. We offer a wide selection of FELPRO Cooling and Climate Controls, specifically designed for the 2021 Ford F-450 Super Duty. With over 1 FELPRO brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $10.99. Plus, with over 110 customer reviews and an average rating of 4.6 stars, you can trust that our FELPRO Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.

from $10.99

(110)

Multi-Purpose O-Ring

“It work and price was reasonable”

FAQs for 2021 Ford F-450 Super Duty Cooling and Climate Controls

Which Cooling and Climate Controls are best-sellers for 2021 Ford F-450 Super Duties?

Out of 25 Cooling and Climate Controls that fit 2021 Ford F-450 Super Duties, the following parts are the top sellers:

Engine Coolant Reservoir Cap (10006766) – $22.99
Standard Thermostat: With Seal, 194, 201 Degrees (10647376) – $59.99
Heater Core (10992365) – $76.99

What’s the price range for 2021 Ford F-450 Super Duty Cooling and Climate Controls?

Cooling and Climate Control prices for the 2021 Ford F-450 Super Duty start at $2.99 and go up to $2,150.99 for the most premium parts.

What’s the average price of a Cooling and Climate Control for a 2021 Ford F-450 Super Duty?

The average price for Cooling and Climate Controls for the 2021 Ford F-450 Super Duty is $147.87. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Cooling and Climate Controls for other Ford F-450 Super Duty model years?

Yes, we currently carry Cooling and Climate Controls for 25 model years of Ford F-450 Super Duties between 1999 and 2025. Cooling and Climate Controls are bought most frequently for the following model years: 2022, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Cooling and Climate Controls for my 2021 Ford F-450 Super Duty?

The cheapest 2021 Ford F-450 Super Duty Cooling and Climate Controls we carry in stock are:

THERMOSTAT O-RING (50213631) – $2.99
A/C SERVICE VALVE (50154171) – $4.99
A/C Service Valve Cap, Black, M8 x 1mm (50154176) – $4.99
Coolant Temperature Sensor 1TS1488 (50215081) – $8.99
Multi-Purpose O-Ring (5180902) – $10.99

What are the top-rated Cooling and Climate Controls that fit the 2021 Ford F-450 Super Duty?

Out of 426 reviews by customers, our 2021 Ford F-450 Super Duty Cooling and Climate Controls have an average customer rating of . These are some of the highest-rated Cooling and Climate Control types for the 2021 Ford F-450 Super Duty and their top-rated products:

Blend Doors
- HVAC Blend Door Actuator: 1 Piece (11776221) – $26.49
Engine Cooling Parts
- HVAC Blend Door Actuator: 1 Piece (11776221) – $26.49

What types of Cooling and Climate Controls do you sell for my 2021 Ford F-450 Super Duty?

As of 11/2/25, these are some of the most in-demand types of Cooling and Climate Controls for a 2021 Ford F-450 Super Duty:

Can I get help with 2021 Ford F-450 Super Duty Cooling and Climate Control orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Ford Cooling and Climate Controls and more.

What is your return policy for Ford F-450 Super Duty Cooling and Climate Controls?

Advance Auto Parts keeps returns simple. For new Ford F-450 Super Duty Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.

2021 Ford F-450 Super Duty Cooling and Climate Controls

Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14899)

Carquest Premium – Standard Thermostat: 192 Degrees (Part No.14269)

Dorman – Coolant Tee and Radiator Hose O-Ring Kit (OE Fix) (Part No.926-168)

Carquest Premium – Standard Reservoir Cap: 16 PSI (Part No.10238)

Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35610-1)

Carquest Premium – A/C Desiccant Cartridge Kit (Part No.T83348)

Felpro – Engine Water Pump Gasket (Part No.35478)

Carquest Premium – A/C Blue Orifice Tube (Part No.T38621)

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.433836)

Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.813145)

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T3127)

Driveworks Water Pumps – Water Pump: New, Installation Gasket Included (Part No.58-597)

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA2003)

Dorman – Coolant Housing/Water Outlet: with Housing (Part No.902-1074)

Dorman – Coolant Housing/Water Outlet: with Housing and Gasket, 90 Degree Neck Angle (Part No.902-1107)

KAI – HVA/C Heater Core (Part No.HTR010050)

Carquest Premium – Heater Core (Part No.910568)

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-288)

Motorcraft – BLEND DOOR ACTUATOR (Part No.YH-1958)

Carquest Premium – Blower Motor: With Wheel (Part No.76508)

Motorcraft – Blower Motor: Without Wheel (Part No.MM-852)

Carquest Premium – Temperature Sender With Gauge and Thread Sealant (Part No.WTC1037)

Delphi – Engine Coolant Temperature Sensor (Part No.HTS125)

KAI – Valve Core/Cap Kit (Part No.FTT010108)

Factory Air – Cap & Valve A/C System Seal Kit (Part No.26783)

Dorman – Help – Air Conditioning Service Port Caps (Part No.54374)

Carquest Premium – Heater Core (Part No.910568)

Carquest Premium – Heater Core (Part No.910740)

Felpro – Multi-Purpose O-Ring (Part No.35489)

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10262)

Carquest Premium – Standard Thermostat: With Seal, 194, 201 Degrees (Part No.49240)

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T1305)

Dorman – Coolant Housing/Water Outlet: with Housing (Part No.902-1074)

Motorad – Thermostat Housing Assembly – 194 & 201 Degrees (Part No.TA1061)

Carquest Premium – Radiator (Part No.4113716)

Carquest Premium – Standard Thermostat: With Seal, 160 Degrees, 170 Degrees (Part No.717-160)

Carquest Premium – Standard Thermostat: With Seal, 192 Degrees (Part No.1121-192)

Motorad – Coolant Housing/Water Outlet (Part No.CH1074)

Felpro – Engine Water Pump Gasket (Part No.36020)

Carquest Premium – Coolant Temperature Sensor 1TS1488 (Part No.WTA2354)

Motorcraft – THERMOSTAT O-RING (Part No.RG-571)

Carquest Premium – A/C Block Expansion Valve Kit (Part No.T39517)

Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA2003)

Carquest Premium – A/C Desiccant Bag Kit (Part No.T83387)

Motorcraft – A/C SERVICE VALVE (Part No.YF-37239)

Motorcraft – A/C Service Valve Cap, Black, M8 x 1mm (Part No.YF-37240)

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-288)

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-290)

Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-289)

Carquest Premium – Blower Motor: with Wheel (Part No.75045)

Carquest Premium – Blower Motor: With Wheel (Part No.76508)