2010 GMC Sierra 2500 HD Cooling and Climate Controls

Essential 2010 GMC Sierra 2500 HD Cooling and Climate Controls

Santech – A/C Expansion Valve (Part No.R1045602035SII)

A/C Expansion Valve

from

$87.53
A/C Expansion Valve

Carquest Premium – Multi Purpose Relay (Part No.RAA1256)

Multi Purpose Relay

from

$24.99
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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GM Genuine Parts – Multi-Purpose Relay (Part No.15016745)

Multi-Purpose Relay

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$49.49
GM Genuine Parts Wiring Relays are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These relays help connect or disconnect power to a vehicle accessory when it receives a low voltage signal from a switch. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps connect or disconnect power to vehicle accessories
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Permatex – The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ (Part No.25238)

The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ

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$19.99
Permatex’s The Right Stuff 1 Minute Series offers the fastest return to service in just 1 minute! This leak-proof, elastomeric “Formed-in-place” material is more reliable and longer lasting than pre-cut gaskets. It is blowout resistant and protects against leaks and seepage caused by vibration and thermal expansion. The Right Stuff 1 Minute Grey is specified for high torque and high vibration applications and is formulated to meet or exceed performance standards for long-term sealability, durability and handling.

Product Features:
  • Designed to perform under higher torque loads associated with engines having closely spaced bolt patterns
  • Sensor-safe, non-corrosive, RTV silicone
  • Protects against leaks caused by vibration and thermal expansion
  • Meets performance specs of OE silicone gaskets
  • Quickly returns vehicle to service in just 1 minute
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Carquest Premium – A/C Evaporator Parallel Flow (Part No.T64014)

A/C Evaporator Parallel Flow

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$144.99
Carquest Evaporators are designed to remove heat from the air inside the passenger compartment of a vehicle resulting in cooler air temperatures. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • The design and manufacture of the evaporators result in uniform refrigerant distribution with optimal flow for improved performance and maximum heat transfer.
  • The evaporators are constructed to offer a lightweight, compact design that will fit easily within the engine compartment.
  • The surface treatment on each part ensures optimum water drainage to prevent mold and odors in the system.
  • The evaporators are 100% tested to meet or exceed original equipment specifications. Each part is helium tested to ensure no leaks.
  • O-Rings and gaskets necessary for installation are included.
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Victor Reinz – Engine Coolant Outlet Gasket (Part No.71-13575-00)

Engine Coolant Outlet Gasket

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$9.49
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
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Victor Reinz – Engine Water Pump Installation Kit (Part No.18-10020-01)

Engine Water Pump Installation Kit

from

$9.49
With Victor Reinz gaskets, you can be sure you are getting sealing solutions that deliver OE quality gasket technology and engineering. That is because Victor Reinz is an original equipment supplier and the trusted choice of manufacturers the world over, offering broad coverage for foreign and domestic cars and trucks. In Victor Reinz gasket sets, you get the right combination of components needed for fast, long-lasting repairs.

Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
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ACDelco – Rear Wheel Speed Sensor (Part No.22827364)

Rear Wheel Speed Sensor

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$91.99
ACDelco GM Original Equipment ABS Wheel Speed Sensors are located at each wheel, monitoring the rotation of each wheel, and are GM-recommended replacements for your vehicle’s original components. The sensor provides this speed information to the antilock brake control module for the antilock braking function. These sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Restores ABS function and performance caused by failed wheel speed sensor
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured with GM Original Equipment specification for fit, form, and function
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KAI – A/C Condenser (Part No.CNDDPI4953)

A/C Condenser

from

$94.99
New Platinum Pro A/C Condenser, V6/V8, Without Rear A/C, Without Ambulance Package

Product Features:
  • V6/V8, Without Rear A/C, Without Ambulance Package, Made Of Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Dorman – Clutch Fan Blade: Plastic, Cost Effective And Reliable (Part No.621-104)

Clutch Fan Blade: Plastic, Cost Effective And Reliable

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$61.99
Replace your damaged cooling fan blade with this direct replacement. This vehicle-specific application is engineered for a perfect fit and is made from quality materials to ensure durability and restore proper cooling system operation.

Product Features:
  • Direct replacement – this engine cooling fan blade fits and functions like the original equipment fan blade
  • Quality construction – manufactured from premium materials for a long service life
  • Excellent value – original equipment quality at a lower price
  • Quality tested – has undergone testing to ensure proper fit and performance
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Delphi – Engine Coolant Temperature Sensor (Part No.TS10076)

Engine Coolant Temperature Sensor

from

$50.99
Delphi temperature sensors are built with the latest OE technology; Delphi temperature sensors use durable, one-piece design; Delphi temperature sensors are impervious to electrical noise and interference.

Product Features:
  • Delphi temperature sensors deliver accurate readings and optimal performance
  • Delphi’s one-piece design and automated production process eliminates internal connectors and failure points
  • Each sensor is electrically insulated to eliminate interference from other components in the vehicle
  • Delphi temperature sensors are impervious to electrical noise and interference
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Carquest Premium – HVAC Blower Motor Resistor Connector (Part No.PTA1336)

HVAC Blower Motor Resistor Connector

from

$67.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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GM Genuine Parts – Air Conditioning Compressor High Pressure Cut-Off Switch (Part No.15-5687)

Air Conditioning Compressor High Pressure Cut-Off Switch

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$28.49
GM Genuine Parts HVAC Pressure Switches are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These HVAC pressure switches are a system protective switch that cuts off power to A/C components if the pressure in the system is too low. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Protective switch that discontinues power to A/C components when system pressures are too low
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Dorman – Pigtail -Evap. Canister Vent Valve Solenoid , Red, 2-way with Leads (Part No.645-631)

Pigtail -Evap. Canister Vent Valve Solenoid , Red, 2-way with Leads

from

$37.99
Make better electrical repairs and accessory installations with this pigtail connector. Designed for a clean appearance when installed, it features weatherproof terminals and a locking tab for a reliable quick disconnect electrical connection.

Product Features:
  • Professional appearance – this electrical pigtail is designed for a clean, professional look when installed
  • Convenient solution – this pigtail connector allows the circuit to be quickly disconnected for service or occasional use
  • Durable construction – this pigtail connector features weatherproof seals and a locking tab for a reliable connection
  • Versatile component – this connector can be used in a variety of repairs and custom installations
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Carquest Standard – Reman GM HU6 Compressor w/ Clutch (Part No.DW57901)

Reman GM HU6 Compressor w/ Clutch

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$272.99
Carquest Standard compressors offer reliable, long-lasting performance for a leak-free, dependable repair.

Product Features:
  • Built in a TS16949 certified manufacturing environment to ensure consistent quality that meets or exceeds OE specifications for fit, form, function and durability
  • All remanufactured compressors are built using the latest compressor technology available today and using strict remanufacturing processes
  • All units have new seals, O-rings, gaskets and clutch bearings
  • Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
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Carquest – HVAC Blower Motor Resistor Connector (Part No.PT5793)

HVAC Blower Motor Resistor Connector

from

$41.99
BWD is an aftermarket leader, providing a premium line of engine management products. BWD manufactures and distributes high technology critical components for late model domestic and import vehicles. BWD is constantly evolving to give customers the competitive edge they need to compete in today’s ever-changing marketplace.

Product Features:
  • Our ignition coils use 100% pure copper windings in the primary and secondary bobbins to improve durability and provide higher resistance to internal shorts and dielectric breakdown
  • Our premium ignition coils consist of a special blended formula for the best performance, longest life and better heat dissipation
  • A full E-Lam core of silicon steel and solid brass high voltage terminals protects against corrosion. Our ignition coils are built for maximum output voltage
  • Primary and Secondary windings feature enamel magnet wire for the highest temperature rating in the aftermarket
  • BWD is a global manufacturer of original equipment ignition products, complete quality control is maintained through the manufacturing process from componentry to finished product
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Dorman – Body Bolt With Washer – M6-1.0 X 25mm (sold by each) (Part No.700-251)

Body Bolt With Washer - M6-1.0 X 25mm (sold by each)

from

$1.29
These nuts are manufactured using durable materials and corrosion tested to ensure required strength and longevity.

Product Features:
  • Durable materials – manufactured to specific thread tolerance standards
  • Corrosion tested – hardware undergoes salt spray testing to ensure corrosion resistance
  • Multipurpose usefulness – can be used in a variety of applications, from auto to home
  • Trustworthy quality – backed by team of professional engineers and quality control specialists in the United States
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.799-105)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

from

$5.29
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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ACDelco – Heating and Air Conditioning Air Inlet Door Actuator (Part No.15-73599)

Heating and Air Conditioning Air Inlet Door Actuator

from

$68.99
ACDelco GM Original Equipment HVAC Air Inlet Door Actuators are electric motors attached to the HVAC housing that open or close the air inlet door, allowing the driver to select fresh air or recirculate modes. They are GM-recommended replacements for your vehicle’s original components. These original equipment air inlet door actuators have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Restore air inlet door operation caused by worn actuator
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Imperial – High Performance Radiator Fan Motor (Part No.3855)

High Performance Radiator Fan Motor

from

$247.99
Motors built And tested to OE specifications; OE fit And design; Out of box installation; Quality construction And assembly
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ACDelco – 2-Way Female Black Multi-Purpose Pigtail (Part No.PT131)

2-Way Female Black Multi-Purpose Pigtail

from

$32.49
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Felpro – Engine Coolant Thermostat Housing Gasket (Part No.35762)

Engine Coolant Thermostat Housing Gasket

from

$3.29
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Validated for fit, form, and function
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Dorman – HVAC Blend Door Actuator: 1 Piece (Part No.604-705)

HVAC Blend Door Actuator: 1 Piece

from

$43.99
This air door actuator directly replaces the original actuator on specific vehicle years, makes, models, configurations and positions to restore proper HVAC operation. Please note that many vehicles have several different air door actuators, which are designed for specific positions and functions in the vehicle. To ensure you have what you need, carefully review the application notes for this part to verify it matches the position and function of the actuator you need to replace. In some online ordering systems, you may need to enter your vehicle information first to see the application notes for your vehicle. If you don’t know which actuator position you need to replace, consult a qualified service technician.

Product Features:
  • Direct replacement – made to match the fit and function of the original air door actuator on certain vehicle years, makes, models and configurations
  • Position specific – vehicles often have multiple different HVAC door actuators; review this part’s application notes to verify it matches the location and function of the actuator you need to replace
  • Durable construction – designed and tested to strict standards to help resist wear and electrical burnout for reliable operation and long service life
  • Trustworthy quality – backed by a team of experts and engineers in the United States, and more than a century of experience
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Carquest Premium – A/C Compressor Switch Connector (Part No.PTA1328)

A/C Compressor Switch Connector

from

$15.79
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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KAI – Radiator Support Tie Bar (Part No.GM1225263)

Radiator Support Tie Bar

from

$69.99
New Standard Replacement Radiator Support Upper Tie Bar

Product Features:
  • Made Of Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest – Multi Purpose Relay (Part No.83A1005)

Multi Purpose Relay

from

$17.49
High-quality products that meet OE appearance and performance to provide professional technicians and DIYers with a cost-effective solution.

Product Features:
  • High-quality products that meet OE appearance and performance to
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ACDelco – 12587397 GM Original Equipment Engine Coolant Water Inlet Seal (Part No.G4030310258ACD)

12587397 GM Original Equipment Engine Coolant Water Inlet Seal

from

$8.72
An ACDelco GM Original Equipment Engine Coolant Water Inlet Seal is a GM-recommended replacement for your vehicle’s original component. It seals and helps prevent coolant from leaking out of cooling system components. This original equipment engine coolant water inlet seal has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Seals and helps prevent coolant from leaking out of cooling system components to maintain the proper engine temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – A/C Compressor Relay Connector (Part No.PTA1171)

A/C Compressor Relay Connector

from

$61.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Popular 2010 GMC Sierra 2500 HD Cooling and Climate Controls Categories

2010 GMC Sierra 2500 HD Cooling and Climate Controls

You count on your 2010 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 226 Cooling and Climate Controls ranging in price from $1.29 to $514.99, you’re sure to find everything you need for your 2010 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 24 different brands like Carquest Premium, Permatex, and Felpro. 2010 GMC Sierra 2500 HD Cooling and Climate Controls start as low as $1.29!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 9,984 extensive product reviews on 2010 GMC Sierra 2500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Standard Thermostat: With Seal, 187 Degrees with 4.2 stars and Engine Water Pump: New, Gasket/Seals Included with 4.4 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2010 GMC Sierra 2500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2010 GMC Sierra 2500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2010 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Carquest Premium, Permatex, Felpro, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Engine Cooling Parts. All are waiting to get your 2010 GMC Sierra 2500 HD back on the road. Some of the top-rated ACDelco products in these categories are:
Engine Coolant Temperature Sensor
from $34.99
(1)
Engine Coolant Temperature Sensor
Coolant Temperature Sensors
Multi-Purpose Relay
from $29.99
(1)
Multi-Purpose Relay
Blower Relays

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2010 GMC Sierra 2500 HD, and some of our most reviewed Carquest Premium parts include:
A/C Dark Grey Porous Orifice Tube
from $15.99
(97)
A/C Dark Grey Porous Orifice Tube
Expansion Valve and Orifice Tubes

FAQs for 2010 GMC Sierra 2500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2010 GMC Sierra 2500 HD?

Out of 226 Cooling and Climate Controls for the 2010 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Water Pump Gaskets
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
Water Pump Gaskets
Radiator Cap: 15 PSI
from $14.99
(59)
Radiator Cap: 15 PSI
Coolant Reservoir Caps

What are the top-rated 2010 GMC Sierra 2500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2010 GMC Sierra 2500 HD based on customer reviews/ratings are:
Standard Thermostat: With Seal, 187 Degrees
from $38.99
(45)
Standard Thermostat: With Seal, 187 Degrees
“Works well and fit perfect.”
Engine Water Pump: New, Gasket/Seals Included
from $227.99
(41)
Engine Water Pump: New, Gasket/Seals Included
“My truck”
Adjustable Thermostatic Fan Control
from $22.99
(35)
Adjustable Thermostatic Fan Control
“good price, but does not come with knob to set temp”