2010 GMC Sierra 2500 HD Cooling and Climate Controls

Essential 2010 GMC Sierra 2500 HD Cooling and Climate Controls

ACDelco – Black Multi-Purpose Pigtail (Part No.PT2647)

Black Multi-Purpose Pigtail

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$31.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Imperial – High Performance Radiator Fan Motor (Part No.3855)

High Performance Radiator Fan Motor

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$247.99
Motors built And tested to OE specifications; OE fit And design; Out of box installation; Quality construction And assembly
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Carquest Premium – Engine Coolant Thermostat Housing (Part No.85254)

Engine Coolant Thermostat Housing

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$54.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Meets and/or exceeds OEM standard
  • Includes quality gasket or O-ring  to ensure proper seal (where applicable
  • Coated with corrosion and rust inhibitor
  • 100% leak tested
  • Direct-fit replacement for ease of installation
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Felpro – Engine Coolant Thermostat Housing Seal (Part No.35720)

Engine Coolant Thermostat Housing Seal

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$4.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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Carquest Premium – Multi Purpose Relay (Part No.RAA1737)

Multi Purpose Relay

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$31.49
Carquest premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Carquest Premium – A/C Pressure Transducer Connector (Part No.PTA1151)

A/C Pressure Transducer Connector

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$25.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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KAI – A/C Compressor, Denso, V8 Engine (Part No.ACP010583)

A/C Compressor, Denso, V8 Engine

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$302.99
New Standard Replacement A/C Compressor, Denso, V8 Engine

Product Features:
  • Denso, V8 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – A/C Condenser (Part No.2317)

A/C Condenser

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$212.99
The Carquest condenser is an integral component of the motor vehicle air conditioning system. This part condenses the refrigerant into a liquid to prepare it for entry into the compressor. The condenser is manufactured according to OEM design specificat

Product Features:
  • This is a parallel flow condenser that contains small micro-channels. It is highly recommended that this condenser be replaced if a failure has occurred in the vehicle’s air conditioning system that has resulted in debris contaminating the system. This
  • The Carquest condenser production process includes quality driven details such as using zinc-coated tubes and electrostatic paint spray at high temperatures to provide the best corrosion resistance and durability in our condensers.
  • Continuous molds, laser welding machines, semi-automatic assembly stations and other advanced equipment provide quality products.
  • Each condenser uses only the highest quality raw materials including pure aluminum (not substandard or recycled) to provide the highest quality standards from beginning to finished product.
  • All brackets are designed per OEM specifications to ensure strength and reduce vibration and movement.
  • We leak test 100% of our condensers in helium leak test chambers to ensure the product does not leak.
  • Our condensers are manufactured from rigid design standards to fit OEM dimensions.
  • Each condenser design endures a series of tests that includes performance testing, vibration testing, blast testing, and salt spray testing to simulate real world conditions.
  • Each Carquest condenser is packaged using superior box construction. This box is easy to open and seal. Each condenser is packaged in the box with internal protection to keep the part centered and away from the package edges. The package passes the fre
  • Each condenser uses only the highest quality raw materials including pure aluminum (not substandard or recycled) to ensure the highest quality standards from beginning to finished product.
  • All brackets are designed per OEM specifications to ensure strength and reduce vibration and movement.
  • We leak test 100% of our condensers in helium leak test chambers to ensure the product does not leak. This industry leading process is the most precise method and can detect even the smallest leak. The leak-free condenser is then charged with nitrogen and
  • Our condensers are manufactured from rigid design standards to match OEM dimensions. Each design undergoes a drop fit into the actual vehicle to ensure the final manufactured product provides an easy installation.
  • Each condenser design endures a series of tests that includes performance testing, vibration testing, blast testing, and salt spray testing to simulate real world conditions.
  • vibration testing
  • blast testing
  • and salt spray testing to simulate real world conditions.
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GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)

Air Conditioning System Valve Core

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$10.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repair leaking A/C system, restore A/C function
  • Helps restore A/C Function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Motorad – Coolant Housing/Water Outlet: (Part No.CH6007)

Coolant Housing/Water Outlet:

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$78.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. The construction of this housing is improved over the OE design to fix and update any issues that the OE design may have had.

Product Features:
  • Easy, one step fit and installation
  • No special tools required
  • Meets or exceeds all OEM standards
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Imperial – Adjustable Thermostatic Fan Control (Part No.226204)

Adjustable Thermostatic Fan Control

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$55.99
Adjustable Thermostatic Fan Control. 160-210°F; push-in probe. Controls the operating temperature of Imperial electric fans. Operates up to 2 fans.

Product Features:
  • Adjustable thermostatic fan control
  • 160-210°F push-in probe
  • For use with Imperial electric fans
  • Probe installs into radiator fins
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KAI – Radiator Support (Part No.GM1225245)

Radiator Support

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$79.99
New Standard Replacement Radiator Support Latch, 1500 Crewcab/2500/3500 For SUV Fits 2500 Series And All 8.1 Engine Applications

Product Features:
  • 1500 Crewcab/2500/3500 For SUV Fits 2500 Series And All 8.1 Engine Applications, Made Of Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – ABS Wheel Speed Sensor (Part No.ARA1999)

ABS Wheel Speed Sensor

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$81.99
Advance Auto Parts is committed to providing high-quality ABS sensors. The entire manufacturing process is closely managed to deliver high quality products.

Product Features:
  • High grade materials that are equal to or better than OE provide durability and long service life
  • All ABS sensors are tested for proper fit, form, and function
  • Wire diameter and sheathing same or larger than OE to ensure product quality
  • Glass filled reinforced plastic for superior resistance to automotive fluids, dirt, salt and road debris
  • Includes all necessary brackets and hardware
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Permatex – Sensor-Safe, High-Torque RTV Silicone Gasket Maker (Part No.82194)

Sensor-Safe, High-Torque RTV Silicone Gasket Maker

from

$11.49
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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Factory Air – New Nippondenso 10S17F Clutch Assembly w/ Coil (Part No.47348)

New Nippondenso 10S17F Clutch Assembly w/ Coil

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$185.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • All mounting hardware included
  • Every coil tested for proper ohms
  • Vehicle specific applications
  • Coated to prevent corrosion
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ACDelco – 15-10595 GM Original Equipment Engine Coolant Water Outlet (Part No.G4010349243ACD)

15-10595 GM Original Equipment Engine Coolant Water Outlet

from

$17.99
ACDelco GM Original Equipment Engine Coolant Water Outlets are housings that connect the radiator hoses to the engine, typically housing the engine coolant thermostat. For certain applications, the water outlet contains threaded holes or ports for sensors and switches. These original equipment engine coolant water outlets are GM-recommended replacements for your vehicle’s original components and have been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Instrument Panel Air Duct Air Temperature Sensor (Part No.15-5632)

Instrument Panel Air Duct Air Temperature Sensor

from

$9.99
ACDelco GM Original Equipment HVAC Temperature Sensor is a GM-recommended replacement component for one or more of the following vehicle systems: hvac. This original equipment sensor will provide the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Relay (Part No.P2020846897ACD)

Relay

from

$78.90
Relay

KAI – A/C System Seal Kit (Part No.FTT010692)

A/C System Seal Kit

from

$23.99
New Standard Replacement A/C System Seal Kit, MT2741, L4 Engine

Product Features:
  • MT2741, L4 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – 4 Pole Radiator Fan Motor (Part No.75768)

4 Pole Radiator Fan Motor

from

$126.99
Motor RPM equivalent to or exceeds OEM motor

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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Imperial – Electric Fan – 14" Diameter (Part No.226114)

Electric Fan - 14" Diameter

from

$99.99
Product Features:
  • Motors built and tested to quality specifications
  • 14 in. universal fit reversible fan
  • 1250 CFM
  • UNIVERSAL fan, NOT a direct OE replacement. Measure core and verify space.
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Dorman – Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In (Part No.45813)

Rivet-Push In-Hole Diameter .500 In-Head Diameter 1 In-Length .900 In

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$1.99
Constructed of quality materials, this multi-purpose retainer provides the same function and versatility as the original equipment retainer ensuring long service life.

Product Features:
  • Ideal replacement – this retainer matches the fit and function of the original equipment retainer for this vehicle application
  • Quality material – this retainer is made of durable material for long-lasting service
  • Versatile design – this retainer is suitable for a variety of automotive uses
  • Excellent value – this part offers original equipment quality at a competitive cost
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Dorman – Body Bolt – M6-1.0 X 25mm (Part No.963-232D)

Body Bolt - M6-1.0 X 25mm

from

$4.49
These bolts are manufactured using durable materials and corrosion-tested to ensure required strength and longevity.

Product Features:
  • Durable materials – manufactured to specific thread tolerance standards
  • Corrosion tested – hardware undergoes salt spray testing to ensure corrosion resistance
  • Multipurpose usefulness – can be used in a variety of applications, from auto to home
  • Trustworthy quality – backed by team of professional engineers and quality control specialists in the United States
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Carquest Premium – A/C Discharge Line Hose Assembly (Part No.T66003)

A/C Discharge Line Hose Assembly

from

$45.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related air conditioning
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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Carquest Premium – A/C Compressor Switch Connector (Part No.PTA1329)

A/C Compressor Switch Connector

from

$17.79
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.

Product Features:
  • Premium quality materials for longer service life
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Dorman – Pressurized Coolant Reservoir: Black And White, Plastic, Original Equipment Replacement (Part No.603-054)

Pressurized Coolant Reservoir: Black And White, Plastic, Original Equipment Replacement

from

$51.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.

Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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US MOTOR WORKS – Water Pump with Fan Clutch (Part No.MCK1007)

Water Pump with Fan Clutch

from

$158.99
US Motor Works Professional Series Water Pump with Fan Clutch are designed to replace the mechanical components of a cooling system. A proper water pump replacement should include a new fan clutch as the two are connected to the same shaft and work together to move the air and cooling fluid. Replacing one without the other can damage the new part and cause repeat work or engine trouble. This matched set will allow your vehicle continued operation in the demanding environment of today’s engine. All components are brand new and QA inspected for perfect fit and function. Restore your cooling power by installing a US Motor Works Professional Series Water Pump with Fan Clutch.

Product Features:
  • Fan clutch mounts to the water pump and should be replaced at the same time.
  • Matched set for proper water pump or fan clutch replacement
  • Includes mounting hardware, gaskets and accessories as required.
  • Complete mechanical cooling parts replacement
  • Factory tested and 100% new product
  • Meets or exceeds OEM quality
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ACDelco – GM Original Equipment Engine Coolant Thermostat (Part No.G4000225359ACD)

GM Original Equipment Engine Coolant Thermostat

from

$60.69
An ACDelco GM Original Equipment Engine Coolant Thermostat is a temperature controlled valve located in the engine coolant outlet to, or the inlet from, the radiator, and is a GM-recommended replacement for your vehicle’s original component. It controls the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature. This original equipment engine coolant thermostat has been manufactured to fit your specific GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Control the flow of coolant through the radiator to enable the engine to reach and maintain its normal operating temperature
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Popular 2010 GMC Sierra 2500 HD Cooling and Climate Controls Categories

2010 GMC Sierra 2500 HD Cooling and Climate Controls

You count on your 2010 GMC Sierra 2500 HD to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 209 Cooling and Climate Controls ranging in price from $1.29 to $577.99, you’re sure to find everything you need for your 2010 GMC Sierra 2500 HD.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 25 different brands like Permatex, Carquest Premium, and Felpro. 2010 GMC Sierra 2500 HD Cooling and Climate Controls start as low as $1.29!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 10,668 extensive product reviews on 2010 GMC Sierra 2500 HD Cooling and Climate Controls. Some of the top-rated Cooling and Climate Controls products we carry are Radiator Cap: 15 PSI with 4.6 stars and Standard Thermostat: With Seal, 187 Degrees with 4.2 stars.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2010 GMC Sierra 2500 HD below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2010 GMC Sierra 2500 HD

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2010 GMC Sierra 2500 HD running right for years to come. In our inventory you’ll find brands like Permatex, Carquest Premium, Felpro, and even more.

Popular ACDelco Cooling and Climate Controls

You’ll find popular ACDelco brand products across Blend Doors and Engine Cooling Parts. All are waiting to get your 2010 GMC Sierra 2500 HD back on the road. Some of the top-rated ACDelco products in these categories are:
HVAC Blend Door Actuator: 1 Piece
from $251.99
(1)
HVAC Blend Door Actuator: 1 Piece
Air Blend Door Actuators
Multi-Purpose Pigtail
from $37.99
(2)
Multi-Purpose Pigtail
AC Clutch Coil Connectors

Top-Rated Carquest Premium Cooling and Climate Controls


If Carquest Premium are what you’re looking for, our inventory holds plenty. We stock Carquest Premium brand Cooling and Climate Controls for your 2010 GMC Sierra 2500 HD, and some of our most reviewed Carquest Premium parts include:
A/C Dark Grey Porous Orifice Tube
from $15.99
(97)
A/C Dark Grey Porous Orifice Tube
Expansion Valve and Orifice Tubes

FAQs for 2010 GMC Sierra 2500 HD Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2010 GMC Sierra 2500 HD?

Out of 209 Cooling and Climate Controls for the 2010 GMC Sierra 2500 HD, the most popular in our inventory are:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets
Engine Water Pump Gasket
from $6.49
(100)
Engine Water Pump Gasket
Water Pump Gaskets

What are the top-rated 2010 GMC Sierra 2500 HD Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your 2010 GMC Sierra 2500 HD based on customer reviews/ratings are:
Radiator Cap: 15 PSI
from $14.99
(59)
Radiator Cap: 15 PSI
“This cap fit and worked great, no problems at all”
Standard Thermostat: With Seal, 187 Degrees
from $38.99
(45)
Standard Thermostat: With Seal, 187 Degrees
“I’m happy with my purchase.”
Engine Water Pump: New, Gasket/Seals Included
from $216.99
(41)
Engine Water Pump: New, Gasket/Seals Included
“Went to go change the thermostat and the bottom bolt broke, so a new water pump was needed. This one was in stock, so I ordered on the app and went t”