2006 Ford E-250 Econoline Differentials

Keep Your 2006 Ford E-250 Econoline in Top Shape with Quality Differentials

Whether you’re repairing or upgrading your Differential, using high-quality parts is key to keeping your 2006 Ford E-250 Econoline looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Differential Pinion Seals, Differential Bearings, and Differential Covers. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Differentials from Trusted Brands

Looking for a reliable Differential? We’ve got you covered with options from brands you know and trust like National, Valvoline, and Mobil Oil. For example, National Differentials start at just $7.79 with an average 4.3 star rating. Valvoline and Mobil Oil offer similar pricing and quality, backed by strong customer feedback. With over 1,696 reviews and a solid 4 star average, you can shop with confidence knowing other Ford E-250 Econoline owners approve.

Competitive Prices and Extensive Inventory

The average price for a 2006 Ford E-250 Econoline Differential at Advance Auto Parts is around $266.74, with a range that starts at $3.99 and goes up to $1,487.99. With 186 options in stock from 12 trusted brands, finding the right fit is easy. Popular picks like Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart, Wheel Bearing: Direct Fit, 1 Piece, and Bearing Race start at just $7.79 and offer a great balance of form and function.

Explore Related Parts

While you’re upgrading or replacing your Differential, don’t forget to check out other key components like Drive Shafts and Axles and Universal Joints. At Advance Auto Parts, we’re here to help you keep your 2006 Ford E-250 Econoline in peak condition, inside and out.

Essential 2006 Ford E-250 Econoline Differentials

Yukon Gear – Dana 44 JK / 60 / 70U Pinion Nut Washer Replacement (Part No.33164)

Dana 44 JK / 60 / 70U Pinion Nut Washer Replacement

from

$3.99
Product Features:
  • Pinion nut washer for Chrysler 7.25″, 8.25″, 8.75″ with 29 spline pinion, Jeep JK rear, Dana Spicer 60, 70, 70U and 70HD and 2007-2010 Ford 10.5″
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Yukon Gear – Pinion Gear And Thrust Washer (0.750" Shaft) For 8.8" Ford (Part No.33297)

Pinion Gear And Thrust Washer (0.750" Shaft) For 8.8" Ford

from

$8.99
Pinion gear thrust washer (0.750″ shaft) for 8.8″ Ford.

Product Features:
  • Pinion gear thrust washer
  • Fits Ford 8.8″
  • 0.750″ I.D.
See More

Yukon Gear – Grizzly Locker For Dana 60, 4.10 & Down, 40 Spline (Part No.28024)

Grizzly Locker For Dana 60, 4.10 & Down, 40 Spline

from

$1145.99
The Yukon Grizzly Locker is the ultimate in locking differentials for street, off-road, & drag racing. Grizzly Lockers provide 100% power to both tires, while still allowing for disengagement while negotiating turns. The Yukon Grizzly locker is a mechanical locking differential. It features a forged case and 8620 internals for maximum strength. It’s patented design reduces common locker failures. All units assembled in the USA! All Grizzly Lockers are backed by the best warranty in the business! Yukon covers the replacement unit and covers any collaterally damaged parts and associated labor, up to $2,000! This is a narrow case locker. If you have a wide housing, please order two DS 42563 with your locker. This locker is ABS compatible.

Product Features:
  • Fits Dana Spicer 60 with 40 spline axles
  • 4.10 and down ratio only
  • Patented internal design reduces common locker failures
  • 8620 internals for added strength
  • Assembled in the USA
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Yukon Gear – Trac Loc For Ford 9" Wtih 31 Spline Axles – Street Design (Part No.26010)

Trac Loc For Ford 9" Wtih 31 Spline Axles - Street Design

from

$789.99
The Yukon Dura Grip provides aggressive yet smooth traction to give you the confidence & performance you need. Get longer life and better traction with the heavy duty Yukon Dura Grip Positraction. The Yukon Trac Loc uses a nodular case, billet side hat, and forged internals for higher strength than stock Trac-Locs. The units use composite clutches for high performance and long life. All units are Rebuildable. Yukon offers a one year warranty against manufacturing defects.

Product Features:
  • Fits Ford 9″ with 31 spline axles
  • Trac Loc positraction
  • Clutch style positraction
  • Street design
  • Internal gears are manufactured using forged 4320 steel and cut to provide stronger teeth
  • Fully rebuildable
  • Assembled in the USA
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Yukon Gear – Set Up Bearing (Part No.56039)

Set Up Bearing

from

$276.99
Set-up carrier bearing kit (2 bearings, no races) for Dana 60 and 70. 387A. No return.

Product Features:
  • Set up bearing kit
  • Fits Dana Spicer 60
  • Easily slips on and off carrier journals to allow for easier carrier shim adjustment
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Yukon Gear – Cover Bolt For Ford 7.5", 8.8" & 9.75" (Part No.33554)

Cover Bolt For Ford 7.5", 8.8" & 9.75"

from

$6.99
Yukon 1541H alloy replacement rear axle for Dana 60, 70, and 80, 35 spline. (40″ to 43.5″) Full float axle (8×3.96″ ). Yukon 1541H alloy axles offer a strength increase over stock while retaining a low cost. Yukon 1541H alloy rear axles come with a one year warranty against manufacturing defects. This is a full-floating axle.

Product Features:
  • 35 spline
  • 8 x 3.96″ bolt pattern
  • Cut to length design fits 40″-43.5″ applications
  • Fits Dana Spicer 60, 70 and 80
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Yukon Gear – Cross Pin Bolt With 5/16 X 18 Thread For 10.25" Ford (Part No.33241)

Cross Pin Bolt With 5/16 X 18 Thread For 10.25" Ford

from

$11.99
Cross pin bolt with 5/16 x 18 thread for 10.25″ Ford.

Product Features:
  • Cross pin bolt for Ford 9.75″ and 10.25″ with c-clip axles
  • 5/16″ x 18 thread
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USA Standard Gear – Replacement Spider Gear Set For Dana 60, 35 Spline (Part No.39009)

Replacement Spider Gear Set For Dana 60, 35 Spline

from

$198.99
Product Features:
  • Spider gear kit
  • Fits Dana Spicer 60, 35 spline open differential
  • Includes two side gears, two pinion gears, cross pin shaft, roll pin and spider gear thrust washers.
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National – Bearing Race (Part No.HM803110)

Bearing Race

from

$20.49
Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

Product Features:
  • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
  • SMOOTH ROTATION – Crowned raceways for even load distribution
  • OE-STYLE DESIGN – Engineered to meet OE specifications
  • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
  • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
See More

Yukon Gear – Super Carrier Shim Kit For Ford 10.25" (Part No.55004)

Super Carrier Shim Kit For Ford 10.25"

from

$48.99
10.25″ Ford carrier Supershims.

Product Features:
  • Super carrier shim kit for Ford 10.25″ and 10.5″
  • Interlocking design makes installation much easier
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Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon (Part No.887344)

SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon

from

$69.99
Valvoline SAE 75W-140 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our formulation provides exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity and wear resistance, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. It’s recommended for conventional rear axles and transmissions requiring EP gear lubes under high speed, high load, high torque and high horsepower conditions.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -22F to 390F degrees
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5
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Yukon Gear – Pinion Install Kit For Ford 9.75" Differential (Part No.13054)

Pinion Install Kit For Ford 9.75" Differential

from

$349.99
Yukon Pinion installation kits are a terrific solution for gear installation on lower mileage vehicles where the carrier bearings & races can be reused. This kit uses Timken bearings and races along with a high quality pinion seal and small parts. Included in this kit are the pinion bearings and races, crush sleeve (if applicable), complete pinion shim kit, pinion nut, thread locker, and marking compound with brush. Yukon does extensive research for each application to make sure your kit will arrive with all the correct parts you need to install your pinion gear.

Product Features:
  • Fits Ford 9.75″
  • Included are pinion bearings and races, pinion seal, pinion nut, crush sleeve, complete pinion shim kit, and marking compound with brush.
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Powertrax – Lock Right Locker (Part No.1822-LR)

Lock Right Locker

from

$371.99
The Powertrax Lock-Right ultra-strength alloy locker’s straight-line performance is equal to a solid spool, but automatically unlocks in turns. Best suited for extreme off-road to severe on-road use, Powertrax Lock Right lockers replace the spider gears in your open differential carrier using basic tools and without affecting your ring and pinion settings. The whole job can be done in your driveway in a couple of hours, pin included! Powertrax Grip-Lok, Lock-Right Lockers and No-Slip Traction Systems automatically provide 100% traction on-demand, under the toughest circumstances. The Powertrax Grip-Pro and Grip-LS performance limited slips offer smooth dependable torque transfer and traction for the best of both worlds!The Powertrax® Lock-Right Locker provides outstanding traction for off-road machines and race vehicles. Powertrax No-Slip Traction Systems deliver excellent performance to street-driven cars and trucks.
  • Powertrax® lockers range from the original, Lock-Right for serious straight-line performance, to the No-Slip traction system for street-able vehicles.
  • Powertrax® offers three levels of GRIP locking differentials, ranging from the clutch-type GRIP LS with a forged steel case, the gear-driven GRIP PRO and finally the GRIP LOK for extreme traction.
  • Powertrax® = Extreme Traction Systems!
  • See More

    Yukon Gear – Replacement Cover Gasket For Dana 50, Dana 60 & Dana 70 (Part No.23007)

    Replacement Cover Gasket For Dana 50, Dana 60 & Dana 70

    from

    $13.99
    Product Features:
    • Cover gasket
    • Fits Dana Spicer 60, 70, 70U and 70HD
    See More

    Powertrax – Grip PRO Traction System (Part No.GT108028)

    Grip PRO Traction System

    from

    $537.99
    For vehicles that are driven daily, the Powertrax No-Slip Traction System is the latest design in quiet traction-adding differential technology. It combines the automatic street-friendly smooth operation of a limited-slip differential with the traction performance of a locking differential. The Powertrax No-Slip locker easily installs in to your differential carrier using basic tools and without affecting your ring and pinion settings. Powertrax Grip-Lok, Lock-Right Lockers and No-Slip Traction Systems automatically provide 100% traction on-demand, under the toughest circumstances. The Powertrax Grip-Pro and Grip-LS performance limited slips offer smooth dependable torque transfer and traction for the best of both worlds!
    See More

    Yukon Gear – Dana 60 & Dana 70 Power Lok Case Bolt (Part No.33236)

    Dana 60 & Dana 70 Power Lok Case Bolt

    from

    $7.99
    Dana 60 & Dana 70 Power Lok case bolt.

    Product Features:
    • Power Lok case bolt for Dana Spicer 60 and 70
    • 7/16 x 14 thread
    • 3.5″ long
    • 9/16″ hex head
    See More

    Yukon Gear – Standard Open Side Gear And Thruster Washer For 10.25" Ford (Part No.33293)

    Standard Open Side Gear And Thruster Washer For 10.25" Ford

    from

    $11.99
    55P Chevy Passenger Drop Out gasket.

    Product Features:
    • Side gear thrust washer
    • Fits Ford 10.25″
    See More

    Yukon Gear – Chrysler 9.25" And Dana 44 / 60 Tracloc Clutch Guide Replacement (Part No.33249)

    Chrysler 9.25" And Dana 44 / 60 Tracloc Clutch Guide Replacement

    from

    $8.99
    Product Features:
    • Clutch guide for Chrysler 9.25″, Dana Spicer 44 and Dana Spicer 60
    • For Trac Loc positraction applications only
    See More

    Yukon Gear – Replacement Inner Slinger For Dana 60 (Part No.33014)

    Replacement Inner Slinger For Dana 60

    from

    $9.99
    Product Features:
    • Inner oil slinger for Dana Spicer 60
    See More

    Yukon Gear – Seal Housing For Ford 10.25" & 10.5", Zip Locker, With O-Rings (Part No.34040)

    Seal Housing For Ford 10.25" & 10.5", Zip Locker, With O-Rings

    from

    $78.99
    Seal housing for Ford 10.25″ & 10.5″, Zip locker, with o-rings.

    Product Features:
    • Seal housing for Ford 10.25″ and 10.5″
    • Includes o-rings
    See More

    Yukon Gear – Cross Pin Shaft (0.875") For ’86 And Newer 8.8" Ford (Part No.33331)

    Cross Pin Shaft (0.875") For '86 And Newer 8.8" Ford

    from

    $42.99
    Cross pin shaft (0.875″) for ’86 and newer 8.8″ Ford.

    Product Features:
    • Cross pin shaft for Ford 8.8″
    • 0.875″ diameter
    See More

    Richmond Gear – RngPnnInstlKt (Part No.83-1034-B)

    RngPnnInstlKt

    from

    $59.99
    RngPnnInstlKt

    Yukon Gear – Plug Adapter For Extra-Large Clamshell (Part No.56070)

    Plug Adapter For Extra-Large Clamshell

    from

    $47.99
    Plug adapter for extra-large clamshell. No Return.

    Product Features:
    • Plug adapter for Extra Large clamshell
    • Fits carrier bearing puller
    See More

    Motive Gear – Differential Ring and Pinion (Part No.D60-354)

    Differential Ring and Pinion

    from

    $275.99


    Product Features:
    • DANA-60 R/P 3.54 STD MG 24813-5X (USES PRE-LOAD SHIMS)
    See More

    Yukon Gear – Bearing Race Driver (Part No.56010)

    Bearing Race Driver

    from

    $215.99
    Bearing race drive for Ford 10.25″ and 10.5 axle bearing. (TK 3920). No return.

    Product Features:
    • Bearing race driver
    • Fits 3920 race
    • All steel construction
    See More

    USA Standard Gear – Steel Spool For Dana 60 With 30 Spline Axles, 4.10 & Down (Part No.59014)

    Steel Spool For Dana 60 With 30 Spline Axles, 4.10 & Down

    from

    $484.99
    USA Standard ring & pinion sets are the right choice to add confidence to your install. USA Standard Gear offers a full line of ring & pinion sets for a variety of common & hard to find applications. USA standard gear offers a standard one year warranty against defects on their ring & pinion sets.

    Product Features:
    • Fits GM 9.25″ front
    • 9.25″ ring gear
    • 30 spline pinion
    • 12 ring gear bolts
    • 4.11 ratio
    See More

    USA Standard Gear – Master Overhaul Kit for ’09 & Down Ford 8.8" Differential. (Part No.37030)

    Master Overhaul Kit for '09 & Down Ford 8.8" Differential.

    from

    $201.99
    USA Standard Master Overhaul kits let you finish your install with confidence. This kit uses Koyo bearings and races. Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve (if applicable), oil baffles and slingers (if applicable), threading locking compound, marking compound with brush and gasket.

    Product Features:
    • Fits 2009 and down Ford 8.8″
    • Uses Koyo bearings and races
    • Included are carrier bearings and races, pinion bearings and races, pinion seal, complete shim kit, ring gear bolts, pinion nut, crush sleeve, thread locker, marking compound with brush and gasket.
    See More

    Dorman – Help – Differential Shaft Lock Bolt (Part No.81048)

    Differential Shaft Lock Bolt

    from

    $6.79
    This differential pinion shaft lock bolt is designed to match the fit and function of the original part on specified vehicles. Made of quality materials, it is engineered for reliable performance.

    Product Features:
    • Direct replacement – this differential pinion shaft lock bolt matches the fit and function of the factory part on specified years, makes and models
    • Ideal solution – this bolt is a reliable replacement for an original part that is missing or has failed due to fatigue
    • Durable construction – this part is made from quality materials to ensure reliable performance and long service life
    • Trustworthy quality – backed by team of product experts in the United States and more than a century of automotive experience
    See More

    Most Popular Differential Pinion Seals for 2006 Ford E-250 Econolines

    Enhance your 2006 Ford E-250 Econoline with one of the 6 Differential Pinion Seals we have in stock, starting at just $15.99.

    National – Differential Pinion Seal (Part No.100715V)

    Differential Pinion Seal

    from

    $22.49
    National has built a reputation as one of the most respected names in the industry. We have offered premium sealing solutions for more than 75 years. Our design team keeps pace with the industry and provides advanced solutions for today’s vehicles.

    Product Features:
    • Design type: spring loaded; multi-lip
    • Temperature range: -40 Deg. F to 400 Deg. F / -40 Deg. C to 204 Deg. C
    • Excellent high temperature capabilities
    • Compatible with wide range of fluids
    • Delivers quality and reliable performance for every type of repair
    See More

    Motive Gear – Differential Pinion Seal (Part No.9316)

    Differential Pinion Seal

    from

    $16.49
    Motive Gear offers some of the toughest drive train components on the market today. If you are looking for the largest line of performance ring and pinion gear options available with gear sets in a wide range of ratios for nearly every application, both on and off-road, check out Motive Gear. Motive Gear products can be found in the winner’s circle at racing events worldwide. The superior quality of Motive Gear components is the result of years of racing development, outstanding design and state-of-the-art manufacturing methods. Extensive testing is performed on all products by our in-house engineers.
    See More

    Driveworks – Differential Pinion Seal (Part No.S-100715-V)

    Differential Pinion Seal

    from

    $16.99
    Product Features:
    • Brand may vary by location
    See More

    FAG US – Shaft Seal (Part No.SS2923)

    Shaft Seal

    from

    $21.49
    Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

    Product Features:
    • High-precision and High-quality components used in all KITs
    • Coverage of classic and new high-tech solutions for the best system coverage
    See More

    FAG US – Shaft Seal (Part No.SS2852)

    Shaft Seal

    from

    $20.99
    Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

    Product Features:
    • High-precision and High-quality components used in all KITs
    • Coverage of classic and new high-tech solutions for the best system coverage
    See More

    FAG US – Shaft Seal (Part No.SS2865)

    Shaft Seal

    from

    $15.99
    Our wheel seals are engineered using only the highest-quality materials to meet vehicle manufacturer specificatons. We work with suppliers to design seals that meet FAG’s quality standards. Seals are designed to protect wheel end components from contamination – such as dirt, dust, and moisture – and prevent the loss of grease over the life of the bearing. The specifications for wheel seals are very demanding, and the type required depends on the specific application, position and vehicle class.

    Product Features:
    • High-precision and High-quality components used in all KITs
    • Coverage of classic and new high-tech solutions for the best system coverage
    See More

    Best-Selling 2006 Ford E-250 Econoline Differential Bearings

    Upgrade your E-250 Econoline with one of our 5 best-selling Differential Bearings, earning an average 4.5 stars rating across 14 reviews.

    National – Bearing Race (Part No.382A)

    Bearing Race

    from

    $10.99
    Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

    Product Features:
    • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
    • SMOOTH ROTATION – Crowned raceways for even load distribution
    • OE-STYLE DESIGN – Engineered to meet OE specifications
    • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
    • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
    See More

    National – Bearing Race (Part No.LM102910)

    Bearing Race

    from

    $7.79
    Manufactured with premium-grade steel, National taper bearing cups feature crowned raceways to ensure even load distribution.

    Product Features:
    • PREMIUM MATERIALS – Precision manufactured using premium-grade steel for outstanding durability and performance
    • SMOOTH ROTATION – Crowned raceways for even load distribution
    • OE-STYLE DESIGN – Engineered to meet OE specifications
    • COMPREHENSIVE COVERAGE – Industry-leading coverage for domestic and import applications
    • RIGOROUS TESTING – Comprehensive testing throughout design and development processes by National engineers for quality you can count on
    See More

    Driveworks – Tapered Cone Wheel Bearing Assembly (Part No.S-387-AS)

    Tapered Cone Wheel Bearing Assembly

    from

    $18.49
    Value-priced bearing meets all cataloged application requirements.

    Product Features:
    • Brand may vary by location
    See More

    National – Multi-Purpose Bearing (Part No.A-50)

    Multi-Purpose Bearing

    from

    $66.99
    Product Features:
    • CONSISTENT PERFORMANCE: Matched cup and cone components ensure consistent performance
    • PREMIUM MATERIALS: Precision manufactured using premium-grade steel for outstanding durability and performance
    • SMOOTH ROTATION: Crowned raceways and rollers for even load distribution
    • OE-STYLE DESIGN: Engineered to meet OE specifications
    • COMPREHENSIVE COVERAGE: Industry-leading coverage for domestic and import applications
    • RIGOROUS TESTING: Comprehensive testing throughout design and development processes by National engineers for quality you can count on
    See More

    Yukon Gear – 9.25" Chrysler, Dana 60 Semi-Float X/P Bolt, 80 & Up, 5/16" Head, Tapered Shoulder (Part No.33238)

    9.25" Chrysler, Dana 60 Semi-Float X/P Bolt, 80 & Up, 5/16" Head, Tapered Shoulder

    from

    $9.99
    Product Features:
    • Cross pin bolt for Dana Spicer 60 with c-clip axles
    See More

    Top-Quality Differential Covers for 2006 Ford E-250 Econolines

    Choose a high-quality OEM or aftermarket Differential Cover for Ford E-250 Econolines and enjoy top-notch performance from $88.99.

    Yukon Gear – Steel Cover For Dana 60 Standard Rotation (Part No.32321)

    Steel Cover For Dana 60 Standard Rotation

    from

    $114.99
    Product Features:
    • Fits standard rotation Dana Spicer 60
    • Steel
    See More

    Yukon Gear – Hardcore Diff Cover For Dana 50, Dana 60 & Dana 70 (Part No.32352)

    Hardcore Diff Cover For Dana 50, Dana 60 & Dana 70

    from

    $288.99
    Product Features:
    • Nodular iron for added strength
    • Thick design
    • Durable powder coat finish
    • Magnetic drain plug
    • Made in USA
    • High strength stainless steel fasteners
    See More

    Yukon Gear – Polished Aluminum Replacement Cover For Dana 60 (Part No.32024)

    Polished Aluminum Replacement Cover For Dana 60

    from

    $269.99
    Polished aluminum replacement cover for Dana 60 (standard rotation only).

    Product Features:
    • Fits standard rotation Dana Spicer 60
    • Finned polished aluminum
    See More

    Yukon Gear – Finned Aluminum Cover For Ford 10.5", ’08 & Up (Part No.32325)

    Finned Aluminum Cover For Ford 10.5", '08 & Up

    from

    $156.99
    Product Features:
    • Fits Ford 10.5″
    • Steel
    See More

    Yukon Gear – Chrome Replacement Cover For Dana 60 And 61 Standard Rotation (Part No.32005)

    Chrome Replacement Cover For Dana 60 And 61 Standard Rotation

    from

    $89.99
    Chrome replacement cover for Dana 60 and 61(not reverse rotation!).

    Product Features:
    • Fits standard rotation Dana Spicer 60
    • Chrome
    See More

    Pro-King – Differential Carrier Cover (Part No.716C758)

    Differential Carrier Cover

    from

    $88.99
    Pro-King is the leading supplier of transmission and driveline products in the aftermarket.

    Product Features:
    • All products are designed to meet or exceed OE quality, form, fit and funtion.
    See More

    Top Picks for 2006 Ford E-250 Econoline Differential Oil

    Invest in one of our 6 durable Differential Oil for your 2006 Ford, knowing you’re getting trusted brands and expert craftsmanship.

    Mobil 1 – 75W-90 Full Synthetic Gear Lubricant, Extends Gear Life, 1 Quart (Part No.26101)

    75W-90 Full Synthetic Gear Lubricant, Extends Gear Life, 1 Quart

    from

    $19.99
    Mobil 1 Synthetic Gear Lubricant LS 75W-90 is a supreme, multi-purpose automotive gear lubricant that helps to provide exceptional thermal stability and resistance to high temperature oxidation, extending gear life due to minimal deposits. Helps to deliver outstanding protection against low speed/high torque wear with the capability to handle severe driving conditions while delivering smooth efficient performance. Mobil 1 Synthetic Gear Lubricant LS provides exceptional shear stability, corrosion protection, and enhanced frictional properties. Compared to conventional hypoid gear lubricants, Mobil 1 LS 75W-90 performs exceptionally over a wide range of temperatures to reduce wear at start up. Mobil 1 gear lube helps to minimize leakage and reduce contamination while providing good resistance to foaming to maintain film strength for reliable lubrication. Meets or exceeds the requirements of the following industry specifications: API GL-5.

    Product Features:
    • Mobil 1 LS synthetic automotive gear lubricant exceeds the highest level of performance requirements of modern passenger vehicles
    • Helps to provide exceptional thermal stability and resistance to high temperature oxidation and extend gear life due to minimal deposits
    • Delivers outstanding protection against low speed/high torque wear, handling severe driving conditions with smooth, efficient performance
    • Compared to conventional hypoid gear lubricants, performs exceptionally over a wide range of temperatures to reduce wear at start up
    • Provides exceptional shear stability, corrosion protection, and enhanced frictional properties
    • Manufacturer Part Number: 104361
    See More

    Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon (Part No.887344)

    SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-140, 1 Gallon

    from

    $69.99
    Valvoline SAE 75W-140 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our formulation provides exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity and wear resistance, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. It’s recommended for conventional rear axles and transmissions requiring EP gear lubes under high speed, high load, high torque and high horsepower conditions.

    Product Features:
    • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -22F to 390F degrees
    • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
    • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
    • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4
    • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Ford M2C-192A, GM 12346140, Chrysler MS-8985 and API GL-5
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    Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

    Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

    from

    $18.99
    We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

    Product Features:
    • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
    • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
    • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
    • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
    • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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    Yukon Gear – Redline Synthetic "Shock Proof" Oil With Positraction Additive – 4 Quarts (Part No.15005)

    Redline Synthetic "Shock Proof" Oil With Positraction Additive - 4 Quarts

    from

    $148.99
    Redline Synthetic “Shock Proof” Oil with positraction Additive. 4 Quarts.

    Product Features:
    • Includes four quarts of Redline Shockproof oil and one 4oz bottle of Yukon positraction additive
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    Yukon Gear – Redline Synthetic "Shock Proof" Oil – 3 Quarts (Part No.15000)

    Redline Synthetic "Shock Proof" Oil - 3 Quarts

    from

    $99.99
    Redline Synthetic “Shock Proof” Oil. 3 Quarts.

    Product Features:
    • Includes three quarts of Redline Shockproof oil
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    Yukon Gear – Redline Synthetic "Shock Proof" Oil – 4 Quarts (Part No.15004)

    Redline Synthetic "Shock Proof" Oil - 4 Quarts

    from

    $137.99
    Redline Synthetic “Shock Proof” Oil. 4 Quarts.

    Product Features:
    • Includes four quarts of Redline Shockproof oil
    See More

    Our Top-Rated Rear Differential Cover Gaskets for 2006 Ford E-250 Econolines

    Make a smart move for your 2006 Ford E-250 Econoline with our Rear Differential Cover Gasket for $13.99.

    Yukon Gear – Ford 10.25" & 10.5" Cover Gasket (Part No.23008)

    Ford 10.25" & 10.5" Cover Gasket

    from

    $13.99
    10.25″ & 10.5″ cover gasket.

    Product Features:
    • Cover gasket
    • Fits Ford 10.25″ and 10.5″
    See More

    Top-Rated Differential Brands For Your 2006 Ford E-250 Econoline

    When it comes to finding the perfect Differential for your 2006 Ford E-250 Econoline, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 12 trusted brands. We carry the most popular Differential brands including Mobil Oil, Valvoline, and National, and more, all known for their exceptional customer ratings (average brand rating of 4.9 stars) and competitive prices, as low as $7.79. Purchasing a Differential from us here at Advance Auto Parts is a smart move for both you and your 2006 Ford E-250 Econoline, providing peace of mind with parts that meet or exceed OEM standards.

    Popular Mobil Oil 2006 Ford E-250 Econoline Differentials

    If you’re looking for a top-quality Differential for your 2006 Ford E-250 Econoline, Advance Auto Parts has exactly what you need with our selection of Mobil Oil Differentials. We have 1 Mobil Oil Differentials in stock for this fitment, all known for their durability and precision fit. With prices starting at just $19.99, you’ll find the perfect Differential for your needs and budget. Mobil Oil Differentials for the 2006 Ford E-250 Econoline come highly rated, with over 448 customer reviews and an impressive average rating of 4.9 stars. Choosing a Mobil Oil Differential from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.

    Top-Quality Valvoline 2006 Ford E-250 Econoline Differentials

    For those in search of a high-quality Differential for their 2006 Ford E-250 Econoline, Advance Auto Parts offers a great selection of Valvoline Differentials. With 1 Valvoline Differentials in stock, you can trust you’re getting top-tier parts designed for durability and a perfect fit. Prices for these Differentials start at just $69.99, giving you a range of options to suit your budget. Backed by over 364 customer ratings and an average rating of 4.8 stars, Valvoline Differentials provide both reliability and excellent performance. Choosing a Valvoline Differential from Advance Auto Parts is a smart investment in your vehicle’s performance and longevity.

    FAQs for 2006 Ford E-250 Econoline Differentials

    What are the best-selling Differentials for 2006 Ford E-250 Econolines?

    Out of 186 Differentials that fit 2006 Ford E-250 Econolines, the following parts are the top sellers:

    What’s the price range for 2006 Ford E-250 Econoline Differentials?

    The prices of Differentials for the 2006 Ford E-250 Econoline range from $3.99 up to $1,487.99 for the most premium parts.

    What is the average price of a Differential for a 2006 Ford E-250 Econoline?

    The average price for Differentials for the 2006 Ford E-250 Econoline is $266.74. Keep in mind the variety of part types within our Differential category, where you are likely to find a wide range of prices across a variety of parts and components.

    Does Advance Auto Parts sell Differentials for other Ford E-250 Econoline model years?

    Yes, we carry Differentials for 30 model years of Ford E-250 Econolines between 1975 and 2005. The following model years are the most popular for Differential purchases: 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, and 1997.

    What are the cheapest Differentials for my 2006 Ford E-250 Econoline?

    The cheapest 2006 Ford E-250 Econoline Differentials we carry are:

    Does Advance Auto Parts sell Differentials for any other 2006 Ford models?

    Yes. We stock Differentials for 21 other popular 2006 Ford models. Some of the most popular are 2006 F-150 Differentials, 2006 Mustang Differentials, 2006 E-150 Econoline Differentials, 2006 Explorer Differentials, and 2006 F-250 Super Duty Differentials.

    What types of Differentials do you sell for my 2006 Ford E-250 Econoline?

    As of 11/2/25, these are some of the most in-demand types of Differentials for a 2006 Ford E-250 Econoline:

    Can I get help with 2006 Ford E-250 Econoline Differential orders?

    Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Ford Differentials and more.

    What is your return policy for Ford E-250 Econoline Differentials?

    Advance Auto Parts keeps returns simple. For new Ford E-250 Econoline Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.