Mercedes-Benz S350 Engine Cooling Parts

Your One-Stop Shop For Trusted Mercedes-Benz S350 Engine Cooling Parts

If you’re in search of Mercedes-Benz S350 Engine Cooling Parts aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 49 Engine Cooling Parts from top brands with prices ranging from $2.46 to $778.83.

Beyond great prices, we stock trusted brands manufacturing all types of Engine Cooling Parts for your Mercedes-Benz S350. Of the 16 OEM and aftermarket parts brands we carry, some of the most popular are Permatex, Carquest Premium, and Dorman.

And don’t forget to read customer reviews across all Engine Cooling Parts categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Engine Cooling Parts have to cost top dollar, and we prove it. Browse our top Mercedes-Benz S350 Engine Cooling Parts below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

Essential Mercedes-Benz S350 Engine Cooling Parts

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10253)

Engine Coolant Reservoir Cap

from

$19.79
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Carquest Premium – Radiator: With Transmission Oil Cooler (Part No.412875)

Radiator: With Transmission Oil Cooler

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$399.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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APA/URO Parts – Water Pump Pulley (Part No.G302066529APA)

Water Pump Pulley

from

$73.47
Water Pump Pulley

Motorad – Integrated Thermostat Housing: With Seal, 198 Degrees (Part No.975-198)

Integrated Thermostat Housing: With Seal, 198 Degrees

from

$124.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
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Carquest Premium – Engine Cooling Fan Motor Relay (Part No.RAA1978)

Engine Cooling Fan Motor Relay

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$17.99
CARQUEST premium engine management products provide the right products for a wide range of domestic and import applications. Delivering the highest performance and durability under demanding conditions.
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Hella – Coolant Level Sensor (Part No.G1050101126HEL)

Coolant Level Sensor

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$26.44
Coolant Level Sensor

Behr – Radiator Drain Plug (Part No.G106034117BEH)

Radiator Drain Plug

from

$6.23
Radiator Drain Plug

Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T2288)

Engine Water Pump: New, Gasket/Seals Included

from

$185.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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Carquest Premium – Engine Electric Water Pump: New, Plastic Housing (Part No.T1253)

Engine Electric Water Pump: New, Plastic Housing

from

$204.99
Carquest Premium auxiliary water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, impeller, controller, gaskets, and seals are designed for long-lasting service life. These electric water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium auxiliary water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • Built to meet or exceed OE fit, form and function
  • All components necessary for installation are supplied with pump
  • 100% tested for reliable performance
  • Follow all enclosed instructions to maximize pump life and validate warranty
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Carquest Premium – Coolant Temperature Sensor with O-Ring (Part No.WTC1075)

Coolant Temperature Sensor with O-Ring

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$25.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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Rein – Temperature Sensor (Part No.ELC0074)

Temperature Sensor

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$14.99
Rein Automotive OE temperature sensors are made to factory specifications ensuring proper fit, form and function. The temperature sensor is used to report exhaust temperatures to the vehicle’s ECU. The vehicle uses this information to control engine and emission paramaters. Rein temperature sensors include a vehicle specific connector that fits directly into the factory plug. Our quality temperature sensors aim to provide the professional repair technician and vehicle owner the peace of mind and trust that is expected from an OE component.

Product Features:
  • Direct OE replacemet
  • Designed to meet or exceed factory specifications
  • Made using high quality materials
  • Uses vehicle specific style connector for quick replacement.
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Permatex – Sensor-Safe, High-Torque RTV Silicone Gasket Maker (Part No.82194)

Sensor-Safe, High-Torque RTV Silicone Gasket Maker

from

$11.49
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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Rein – Radiator Mount (Part No.AVM0699)

Radiator Mount

from

$19.99
Anti-vibration parts dampen vibration harmonics from the engine and drive line components to rest of the vehicle. This in turn reduces vibration and noise which can be felt and heard while the vehicle is in operation. Rein Automotive anti-vibration parts are application specific and match the design and function of the OE parts.

Product Features:
  • Rubber components match the shore hardness of the original equipment bushing to ensure maximum performance and product longevity.
  • Part has a high corrosion resistance for maximum life.
  • Produced with high quality materials to ensure maximum life and a smooth ride.
  • Made by the OE manufacturer.
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Felpro – Engine Water Pump Gasket (Part No.35910)

Engine Water Pump Gasket

from

$22.49
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Felpro – Engine Water Pump Gasket (Part No.35912)

Engine Water Pump Gasket

from

$7.99
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Elring – Water Pump Gasket (Part No.G3040656911ELR)

Water Pump Gasket

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$9.12
Water Pump Gasket

Permatex – The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ (Part No.25238)

The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ

from

$19.99
Permatex’s The Right Stuff 1 Minute Series offers the fastest return to service in just 1 minute! This leak-proof, elastomeric “Formed-in-place” material is more reliable and longer lasting than pre-cut gaskets. It is blowout resistant and protects against leaks and seepage caused by vibration and thermal expansion. The Right Stuff 1 Minute Grey is specified for high torque and high vibration applications and is formulated to meet or exceed performance standards for long-term sealability, durability and handling.

Product Features:
  • Designed to perform under higher torque loads associated with engines having closely spaced bolt patterns
  • Sensor-safe, non-corrosive, RTV silicone
  • Protects against leaks caused by vibration and thermal expansion
  • Meets performance specs of OE silicone gaskets
  • Quickly returns vehicle to service in just 1 minute
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Permatex – Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ (Part No.22071)

Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ

from

$6.99
Permatex Water Pump & Thermostat RTV Silicone Gasket Maker is a noncorrosive, sensor-safe RTV silicone gasket material formulated for water pumps and thermostat housings. Permatex Water Pump & Thermostat has the highest water-glycol resistance available in an RTV silicone.

Product Features:
  • Sensor-safe, noncorrosive RTV silicone gasket material
  • Formulated specifically for water pumps and thermostat housings
  • Highest water-glycol resistance available in RTV silicone
  • Superior adhesion and flexibility
  • Can be used as a gasket maker or dressing
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Permatex – Sensor-Safe, High Torque RTV Silicone Gasket Maker (Part No.22074)

Sensor-Safe, High Torque RTV Silicone Gasket Maker

from

$6.99
Permatex Ultra Grey is specified for high torque and high vibration applications. Ultra Grey offers a sensor-safe, low odor, non-corrosive formula and is OEM specified to fit dealership warranty requirements. This high performance gasket maker meets performance specs of OE silicone gaskets and can be used on high torque and vibration applications such as valve covers, water pump, intake manifold end seals ad thermostat housings.

Product Features:
  • High torque and rigidity
  • Sensor-safe, non-corrosive formula
  • OEM specified
  • Low-odor, non-corrosive formula
  • Ideal for closed spaced bolt patterns
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Rein – Expansion Tank (Part No.EPT0003)

Expansion Tank

from

$77.99
Rein Automotive OE quality expansion tanks, install, fit and perform the way the original manufacturer intended. These tanks are designed to match or exceed the OE materials used and are produced from virgin plastic with no regrind to prevent cracking from heat cycles and ensure the plastic is durable and will have a long service life.

Product Features:
  • Produced from virgin plastic meeting/exceeding OE specifications and ensuring long life
  • Resistant to cracking and wear from heat cycles preventing coolant loss
  • Direct fitment allows easy installation
  • Manufactured to strict engineering standards/specifications in materials and tolerances
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Dorman – Pressurized Coolant Reservoir: Black And Clear, Plastic, Original Equipment Replacement (Part No.603-254)

Pressurized Coolant Reservoir: Black And Clear, Plastic, Original Equipment Replacement

from

$82.99
This replacement engine coolant reservoir is manufactured from quality materials to withstand the stresses of underhood heat and engine vibration. It is engineered and manufactured to match the fit and function of the original part.

Product Features:
  • Direct replacement – this engine coolant reservoir matches the fit and function of the original part
  • Ideal solution – engineered for a seamless installation
  • Durable construction – manufactured from quality materials to withstand underhood heat and vibration
  • Trustworthy design – backed by 100 years of automotive aftermarket experience
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Behr – Expansion Tank (Part No.G1030275032BEH)

Expansion Tank

from

$77.11
The Behr expansion tank is made of the highest quality materials and is engineered to meet or exceed the OEM specifications for performance, fit and durability.

Product Features:
  • OE-Equivalent and Direct Fit for easy Installation.
  • OE style connections and fittings.
  • Made of highly durable materials.
  • Resistant to thermal wear and cracking.
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Felpro – Engine Coolant Thermostat Housing Seal (Part No.35908)

Engine Coolant Thermostat Housing Seal

from

$4.79
Fel-Pro gaskets offer 100% vehicle sealing with application-specific materials to give you sealing solutions with the performance and durability professionals trust

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design to ensure a perfect fit
  • Engineered and manufactured specifically for the repair environment
  • Unsurpassed quality you can trust
  • Each Fel-Pro gasket, no matter how small, is engineered to exacting standards with proprietary design, engineering and manufacturing processes
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Engine Cooling Parts Brands You Can Trust For Your Mercedes-Benz S350

16 trusted brands of Engine Cooling Parts line our shelves, ready to help keep your Mercedes-Benz S350 running smooth. Below are some of the most popular brands and their top Engine Cooling Parts offerings:

Popular Permatex Engine Cooling Parts

Permatex products for the Mercedes-Benz S350 span several categories. Some of the highest-rated Permatex Engine Cooling Parts that will fit your Mercedes-Benz S350 are:
The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ
from $19.99
(2)
The Right Stuff: 1 Minute Gasket Maker: Grey, 3 OZ
Engine Water Pump Inlet Pipe Gaskets
Sensor-Safe, High Torque RTV Silicone Gasket Maker
from $6.99
(9)
Sensor-Safe, High Torque RTV Silicone Gasket Maker
Engine Water Pump Inlet Pipe Gaskets
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets

Top Mercedes-Benz S350 Engine Cooling Parts from Permatex

Your Mercedes-Benz S350 will be purring again thanks to Permatex brand Engine Cooling Parts available for online order or in-store pick up. Popular Permatex parts include:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets

Most Purchased Mercedes-Benz S350 Engine Cooling Parts from Permatex

When you buy the most frequently purchased Permatex brand Engine Cooling Parts, you can be confident it will be the right part for your Mercedes-Benz S350. Here are the Permatex Engine Cooling Parts Advanced Auto customers buy the most:
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
from $6.99
(288)
Water Pump & Thermostat RTV Silicone Gasket Maker, 0.5 OZ
Engine Water Pump Inlet Pipe Gaskets
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
from $11.49
(95)
Sensor-Safe, High-Torque RTV Silicone Gasket Maker
Water Pump Housing Gaskets
Engine Water Pump: New, Gasket/Seals Included
from $189.99
(17)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps

FAQs for Mercedes-Benz S350 Engine Cooling Parts

What are the most purchased Engine Cooling Parts for the Mercedes-Benz S350?

Out of 49 Engine Cooling Parts for the Mercedes-Benz S350, the most popular in our inventory are:
Engine Water Pump: New, Gasket/Seals Included
from $189.99
(17)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps
Integrated Thermostat Housing: With Seal, 192 Degrees
from $49.49
(5)
Integrated Thermostat Housing: With Seal, 192 Degrees
Thermostat and Water Outlet Assemblies
Engine Coolant Reservoir Cap
from $19.79
(1)
Engine Coolant Reservoir Cap
Coolant Reservoir Caps

What are the top-rated Mercedes-Benz S350 Engine Cooling Parts?

Top-rated Engine Cooling Parts for your Mercedes-Benz S350 based on customer reviews/ratings are:
Engine Water Pump: New, Gasket/Seals Included
from $247.99
(1)
Engine Water Pump: New, Gasket/Seals Included
“Perfect fit”