Mercedes-Benz E500 Thermostat and Water Outlet Assemblies

Your Mercedes-Benz E500 will be happy to know that the search for the right Thermostat and Water Outlet Assemblies you’ve been looking for is over! Advance Auto Parts has 3 different Thermostat and Water Outlet Assemblies for your vehicle, ready for shipping or in-store pick up. The best part is, our Mercedes-Benz E500 Thermostat and Water Outlet Assemblies start from as little as $49.49.

When it comes to your Mercedes-Benz E500, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Thermostat and Water Outlet Assemblies brands so you can shop with complete confidence. Some of our top Thermostat and Water Outlet Assemblies brands are Carquest Premium and Dorman. We’re sure you will get the right product to keep that E500 running for a long time.

We even have reviews of our OEM and aftermarket Thermostat and Water Outlet Assemblies products to help you buy with confidence. Hear from other customers via the 35 reviews on parts for your Mercedes-Benz E500.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Thermostat and Water Outlet Assemblies for your E500, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 25 Mercedes-Benz Thermostat and Water Outlet Assemblies

Carquest Premium – Integrated Thermostat Housing: With Seal, 192 Degrees (Part No.14569)

Integrated Thermostat Housing: With Seal, 192 Degrees

from

$49.49
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees (Part No.788-217)

Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees

from

$188.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Seal, 217 Degrees (Part No.952-217)

Integrated Thermostat Housing: With Seal, 217 Degrees

from

$217.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Seal, 189 Degrees (Part No.623-189)

Integrated Thermostat Housing: With Seal, 189 Degrees

from

$59.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Seal, 189 Degrees (Part No.944-189)

Integrated Thermostat Housing: With Seal, 189 Degrees

from

$49.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 212 Degrees (Part No.785-212)

Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 212 Degrees

from

$257.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Carquest Premium – Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees (Part No.49452)

Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees

from

$214.99
Carquest Premium Integrated Housing Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees (Part No.940-212)

Integrated Thermostat Housing: With Sensor, With Gasket, 212 Degrees

from

$188.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 207 Degrees (Part No.1015-207)

Integrated Thermostat Housing: With Sensor, Spring Clip, Seal, 207 Degrees

from

$213.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 212 Degrees (Part No.942-212)

Integrated Thermostat Housing: With Sensor, With Seal, 212 Degrees

from

$171.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Rein – Thermostat Assembly 100C (Part No.CTA0020)

Thermostat Assembly 100C

from

$128.99
Rein Automotive OE quality thermostat assemblies install, fit and perform the way the original manufacturer intended. These assemblies are designed to meet or exceed the OE materials used. Rein thermostat housings are constructed of metal or plastic based on vehicle specific factory requirements. The housings are constructed from molds cast directly from the OEM parts to meet the strict tolerances of the vehicle’s factory specifications. This ensures a smooth and easy installation, just as one would expect to find with OE quality. Rein thermostats are produced with high-quality metals and components to ensure proper durability and service life. The thermostats are temperature calibrated to have a consistent and precise response suiting cooling system needs. Our quality thermostat assemblies aim to provide the profession repair technician and vehicle owner the peace of mind and trust that is expected from an OE quality component.

Product Features:
  • Matches original equipment design specifications
  • All gaskets or seals necessary for installation are supplied with thermostats
  • Manufactured to strict engineering standards/specifications in materials and tolerances
  • Thermostat set to 100 degrees Celsius to maintain optimal running temperature
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Carquest Premium – Integrated Thermostat Housing: With Seal, 176 Degrees (Part No.14598)

Integrated Thermostat Housing: With Seal, 176 Degrees

from

$49.99
Carquest Premium Thermostats are manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Motorad – Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees (Part No.785-217)

Integrated Thermostat Housing: With Sensor, With Seal, 217 Degrees

from

$222.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Seal, 212 Degrees (Part No.902-5184)

Thermostat Assembly: Includes Housing, Thermostat, and Seal, 212 Degrees

from

$676.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 217 Degrees (Part No.902-5847)

Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 217 Degrees

from

$613.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Housing, Sensor, and O-Ring, 217 Degrees (Part No.902-5844)

Thermostat Assembly: Includes Housing, Sensor, and O-Ring, 217 Degrees

from

$422.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 212 Degrees (Part No.902-5160)

Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 212 Degrees

from

$412.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Sensor, Housing, Bolts, O-Ring, and Washers (Part No.902-5842)

Thermostat Assembly: Includes Sensor, Housing, Bolts, O-Ring, and Washers

from

$375.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Housing, Sensor, O-Ring, and Seal, 212 Degrees (Part No.902-5843)

Thermostat Assembly: Includes Housing, Sensor, O-Ring, and Seal, 212 Degrees

from

$352.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Dorman – Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 207 Degrees (Part No.902-5187)

Thermostat Assembly: Includes Sensor, Housing, and Thermostat, 207 Degrees

from

$339.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Integrated Thermostat Housing: With Seal, 217 Degrees (Part No.995-217)

Integrated Thermostat Housing: With Seal, 217 Degrees

from

$259.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

Dorman – Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees (Part No.902-5850)

Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 198 Degrees

from

$249.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Carquest Premium – Thermostat (Part No.49382)

Thermostat

from

$242.99
Original equipment design provides exact fit and performance.

Product Features:
  • Precise fitting sealing edges prevent leakage and premature cooling.
  • Self-cleaning and self-aligning thermostat valve.
  • Stainless steel assembly and springs are engineered for long life and smooth performance.
See More

Dorman – Thermostat Assembly: Includes Housing, Gasket, and Sensors, 217 Degrees (Part No.902-5177)

Thermostat Assembly: Includes Housing, Gasket, and Sensors, 217 Degrees

from

$236.99
This replacement engine coolant thermostat housing assembly is engineered to match the fit and durability of the stock housing assembly on specified vehicles. It is designed to withstand extreme temperature changes to extend service life.

Product Features:
  • Ideal replacement – this engine coolant thermostat housing assembly directly replaces the original water outlet on specified vehicle years, makes and models
  • Durable construction – this part is specifically designed to withstand extreme temperature changes and resist cracking and leaking
  • Cost-effective and reliable – offers original manufacturer quality at lower cost than getting replacement at dealer
  • Industry-leading design – professionally engineered by the aftermarket leader in replacement thermostat housing assemblies
See More

Motorad – Integrated Thermostat Housing: With Seal, 198 Degrees (Part No.967-198)

Integrated Thermostat Housing: With Seal, 198 Degrees

from

$226.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. This integrated thermostat housing will meet and exceed the expectations of the OE thermostat to insure the best product for your cooling system. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant as well as the design and function of the housing. Offset design, air relief valve, and OEM style seals included where applicable.

Product Features:
  • High grade stainless steel and copper construction
  • Meets or exceeds OEM standards
  • Consistent and precise response to cooling system needs
  • Original equipment design for worry-free direct fit replacement
  • 100% tested and calibrated
See More

FAQs for Mercedes-Benz E500 Thermostat and Water Outlet Assemblies

What are the most popular Thermostat and Water Outlet Assemblies for the Mercedes-Benz E500?

With 2 brands you can trust, our most popular Thermostat and Water Outlet Assemblies for the Mercedes-Benz E500 are:
Integrated Thermostat Housing: With Seal, 192 Degrees
from $49.49
(5)
Integrated Thermostat Housing: With Seal, 192 Degrees
Thermostat and Water Outlet Assemblies
Integrated Thermostat Housing: With Seal, 176 Degrees
from $49.99
This product is not rated
Integrated Thermostat Housing: With Seal, 176 Degrees
Thermostat and Water Outlet Assemblies
Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 176 Degrees
from $58.99
This product is not rated
Thermostat Assembly: Includes Housing, Thermostat, and Gasket, 176 Degrees
Thermostat and Water Outlet Assemblies