Lexus IS350 Cooling and Climate Controls

Essential Lexus IS350 Cooling and Climate Controls

Factory Air – O-Ring & Gasket A/C System Seal Kit (Part No.26816)

O-Ring & Gasket A/C System Seal Kit

from

$36.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Factory Air.

Product Features:
  • All the seals needed to complete the job
  • Compatible with both R134a and R12 refrigerants
  • Application specific
  • SUV and rear air applications
  • All the seals needed to complete the job
  • Compatible with both R134a and R12 refrigerants
  • Application specific
  • SUV and rear air applications
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Carquest Premium – New Compressor with Clutch, Nippondenso 6SBU16C (Part No.T158347)

New Compressor with Clutch, Nippondenso 6SBU16C

from

$694.99
New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications.

Product Features:
  • All compressors go through sophisticated testing and leak test processes
  • Includes specific electrical connector to eliminate splicing
  • For ease of installation this compressor includes all gaskets, O-rings or sealing washers needed to repair your car
  • Validated for fit, form, and function to OE standards
  • New Compressors meet or exceed OE specifications
  • New Compressors are validated for the equivalent of 100,000 miles
  • New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
  • New Compressors come with direct fit connectors for ease of installation and to help eliminate splicing
  • New Compressors come with the R12/R134A/1234yf required O-rings /sealing washers to install the compressor
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T5105)

Engine Water Pump: New, Gasket/Seals Included

from

$89.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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Carquest Premium – Radiator (Part No.813477)

Radiator

from

$178.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
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Carquest Premium – ABS Wheel Speed Sensor (Part No.ARC2542)

ABS Wheel Speed Sensor

from

$180.99
Carquest Premium anti-lock brake system (ABS) wheel speed sensors are designed to perform in harsh environments and meet or exceed original equipment (O.E.) specifications. Carquest Premium ABS sensors are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Each ABS sensor undergoes extensive validation testing to ensure long-lasting performance and reliability. Carquest Premium ABS sensors are part of our Carquest Vehicle Solutions, which is a full line of engine management and electronics products that help control ignition, fuel delivery and emission systems. Carquest Vehicle Solutions are OE-quality parts designed, engineered and tested by world-class manufacturers to ensure a reliable and long-lasting repair.

Product Features:
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • O-rings or seals are included (where applicable)
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Includes all necessary brackets and grommets for easier installation
  • Extensive design validation testing and 100% end-of-line tested
  • Fluorocarbon high-temperature o-ring seals coated with lubricant for easy installation prevents hub contamination.
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
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Carquest Premium – A/C Suction Line Hose Assembly (Part No.T55689)

A/C Suction Line Hose Assembly

from

$105.99
Carquest Hose Assemblies are designed to carry refrigerant in an air conditioning system. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • 100% of hose assemblies use Goodyear hoses that meet original equipment specifications for wall thickness and permeation.
  • Tubes and mufflers are designed to meet original equipment specifications for wall thickness.
  • Fittings are designed to couple and seal to eliminate leaks. Trivalent plating is used on steel fittings to enhance corrosion resistance. The fittings conform to original equipment specifications to allow for the proper fit with related A/C components.
  • Welds and crimps meet and exceed original equipment tension specifications.
  • Manufactured to allow flexibility in the hose to conform to engine compartments.
  • O-Rings necessary for installation are included.
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Carquest Premium – A/C Plate and Fin Evaporator (Part No.T54822)

A/C Plate and Fin Evaporator

from

$118.99
Carquest Evaporators are designed to remove heat from the air inside the passenger compartment of a vehicle resulting in cooler air temperatures. They are manufactured to meet or exceed original equipment specifications and are designed to easily fit into the engine compartment.

Product Features:
  • The design and manufacture of the evaporators result in uniform refrigerant distribution with optimal flow for improved performance and maximum heat transfer.
  • The evaporators are constructed to offer a lightweight, compact design that will fit easily within the engine compartment.
  • The surface treatment on each part ensures optimum water drainage to prevent mold and odors in the system.
  • The evaporators are 100% tested to meet or exceed original equipment specifications. Each part is helium tested to ensure no leaks.
  • O-Rings and gaskets necessary for installation are included.
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Carquest Premium – Multi-Use Connector (Part No.PTA1465)

Multi-Use Connector

from

$49.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Sealed connections (where applicable) to prevent environmental corrosion and performance issues
  • Global coverage for import and/or domestic applications
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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Carquest Premium – HVAC Gaseous Pollutant Sensor (Part No.TAA1117)

HVAC Gaseous Pollutant Sensor

from

$262.99
Also known as the Air Quality Sensor, this sensor is part of the HVAC system or climate control system of the vehicle. This sensor reports air pollutants to the climate control system which when high will operate the system to remove possible harmful pollutants from the passenger cabin.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
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Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-576)

Radiator Fan Assembly: Dual, Cost Effective and Reliable

from

$541.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
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KAI – A/C Desiccant Element (Part No.ACM010005)

A/C Desiccant Element

from

$17.99
New Standard Replacement A/C Receiver Drier And Desiccant Element

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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KAI – Radiator Support Cover (Part No.LX1224104)

Radiator Support Cover

from

$157.99
New Standard Replacement Upper Radiator Support Cover, Sight Shield

Product Features:
  • Sight Shield, Made Of Polypropylene
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Stant – THERMOSTAT SEAL (Part No.27286)

THERMOSTAT SEAL

from

$1.49
THERMOSTAT SEAL

KAI – Radiator Support (Part No.LX1225115)

Radiator Support

from

$585.99
New Standard Replacement Radiator Support

Product Features:
  • Made Of Steel
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – A/C Valve Core/Cap (Part No.T26783)

A/C Valve Core/Cap

from

$21.99
Carquest A/C Accessories provide a comprehensive offering of premium quality fittings and tools to service all aspects of an a/c service from the most simple fitting replacement to complex diagnostics required for late model applications.
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Carquest Premium – Heater Core (Part No.910695)

Heater Core

from

$109.99
Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications. Carquest Premium provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability. Carquest Premium offers certified heater cores that meet or exceed OE specifications and are all fitment checked in the actual vehicle’s HVAC heater module and are, thus, ready to be installed right out of the box for a “Drop-In Fit”. Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.

Product Features:
  • All heater cores are designed and tested to match or exceed OE specifications for form, fit and performance with a clear focus on obtaining the highest heat transfer performance possible through use of quality materials and manufacturing processes to ensu
  • Carquest Premium heater cores are engineered and manufactured under ISO TS16949 quality systems and are 100% leak tested.
  • Provides value in several ways, including increased thermal performance and resistance to corrosion using enhanced design features, such as the latest fin and tube technology and design standardization for maximum availability.
  • Carquest Premium offers a complete line of automotive heater cores covering 94% of all North American vehicle applications.
  • Our advanced engineering methods coupled with our innovative manufacturing technology provides products to the aftermarket that meet or exceed form, fit, and function of OEM Parts
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Carquest Premium – Multi-Purpose Relay (Part No.RAA1733)

Multi-Purpose Relay

from

$20.99
Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
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Victor Reinz – Engine Coolant Thermostat Housing Gasket (Part No.71-15397-00)

Engine Coolant Thermostat Housing Gasket

from

$5.99
Product Features:
  • Choosing Victor Reinz assures getting OE quality parts in gaskets sets that have the coverage, contents, packaging and electronic cataloging to best meet the needs of the aftermarket.
  • Application specific design provides an exceptional fit.
  • Validated for fit, form, and function.
  • Meets or exceeds original equipment specifications.
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Carquest Premium – Radiator Cap Tester Adapter (Part No.12024)

Radiator Cap Tester Adapter

from

$17.99
Tester adapter for the MT-300 cooling system pressure testers. Professional grade test equipment to ensure an automotive cooling system is operating at the correct pressure. Made from high quality materials to ensure durability. Designed to test automotive coolant caps.

Product Features:
  • Machined metal construction
  • Works with MT-300 pressure tester
  • Tests coolant caps
  • Professional quality
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Carquest – Multi-Purpose Relay (Part No.83A1006)

Multi-Purpose Relay

from

$19.99
Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing ¿ utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) ¿ in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Computer-Aided Design (CAD), laser scanning and 3D printing ┐ utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) ┐ in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
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Felpro – WATER OUTLET GASKET (Part No.35767)

WATER OUTLET GASKET

from

$3.29
Fel-Pro® gaskets are specifically designed for the repair environment to deliver a reliable seal on even the most troublesome applications. Designed for imperfect sealing surfaces and manufactured with proprietary materials, you can count on Fel-Pro for innovative sealing solutions for the real-world repair environment.

Product Features:
  • Meets or exceeds all original equipment specifications
  • Application specific design
  • Manufactured for the sealing repair environment
  • Validated for fit, form, and function
  • Quality that you can trust
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Carquest Premium – A/C Refrigerant Pressure Sensor (Part No.ACA1745)

A/C Refrigerant Pressure Sensor

from

$127.99
The Carquest Premium line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:
  • Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
  • Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
  • All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
  • All units are tested using automated end-of-line testing equipment that pressurizes the sensor and checks full-spectrum functionality and electrical output to ensure each part meets manufacturing specifications before packaging.
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Motorad – Integrated Thermostat Housing: With Seal, 180 Degrees (Part No.660-180)

Integrated Thermostat Housing: With Seal, 180 Degrees

from

$89.99
Manufactured with OEM quality materials and safety standards by an OE Supplier. Stands up to even the most demanding automotive cooling systems. Manufactured with OEM specifications and processes. Copper case and wax compound assures rapid response to temperature changes in the coolant. Offset design, air relief valve, and OEM style seals included where applicable

Product Features:


    Product Features:
    • High grade stainless steel and copper construction
    • Meets or exceeds OEM standards
    • Consistent and precise response to cooling system needs
    • Original equipment design for worry-free direct fit replacement
    • 100% tested and calibrated
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Carquest Premium – A/C Block Type Flange Expansion Valve (Part No.T39283)

A/C Block Type Flange Expansion Valve

from

$70.99
Carquest Expansion Valves are designed to regulate the flow of refrigerant through the air conditioning system to provide optimal cooling to the passenger compartment. Each expansion valve is manufactured to original equipment specifications to perform its function even in the harshest climates. Each part is supplied with the necessary gaskets and o-rings for installation.

Product Features:
  • The bodies of these expansion valves are machined from a single block of aluminum or brass metal.
  • Each expansion valve has settings for tonnage and superheat based on the vehicle specifications.
  • Each expansion valve is tested for function and leakage according to OEM specifications to ensure optimal performance of the air conditioning system.
  • O-Rings necessary for installation are included.
  • O-Rings necessary for installation are included.
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Carquest Premium – Multi-Purpose Relay (Part No.RAA1235)

Multi-Purpose Relay

from

$17.99
Relays are electrical switches used to convert a small electrical load into a circuit capable of handling a high amperage load. Computers and small switches are not designed to carry the higher amperage requirement of a circuit that may have an electric motor, solenoid, or high amperage lighting fixture. Within a relay are contacts that are controlled with electromagnetism, when the circuit switch commands the device on or off, magnetism will pull or release the contact arm closing or opening the contacts within the relay that carry the voltage.

Product Features:
  • Product constructed to meet all design and operating characteristics as intended by the vehicle manufacturer.
  • Computer-Aided Design (CAD), laser scanning and 3D printing – utilizing Fused Deposition Modeling (FDM) and Stereolithography (SLA) – in the part design process ensures speed-to-market and a precise fit guaranteed.
  • Where applicable, robust circuit board design increases durability due to heat, shock, and random electro-magnetic pulses (EMP) and power spikes.
  • Tin plated lead frame prevents corrosion and ensures a reliable terminal connection under adverse ambient conditions.
  • 100% thermo-shock and vibration tested to ensure superior performance in extreme conditions.
  • 100% end-of-line tested to ensure accurate signal output providing product reliability, every time.
See More

Helping You Find the Right Cooling and Climate Controls for Your Lexus IS350

You love your IS350. So we’ve made it easier than ever to help you find Lexus IS350 Cooling and Climate Controls in our online catalog. Our inventory holds 69 aftermarket and OEM Cooling and Climate Controls for your Lexus IS350, ranging from $1.49 to $718.99.

We offer parts from 11 brands trusted to make quality Cooling and Climate Controls for your Lexus IS350. Before you buy, take some time to read through customer reviews. We currently have 6,449 reviews of Lexus IS350 Cooling and Climate Controls from previous customers. Some of the top rated parts include Coolant Temp Sensor Switch with 4.0 stars and Engine Coolant Reservoir Cap with 3.8 stars.

Find your IS350 Cooling and Climate Controls here, order online, and have your order shipped directly to your home. Prefer to have an in-person look at your Lexus IS350 part to confirm it’s just right? You can find your nearest Advance Auto Parts store and confirm they have the part in stock before heading over.

Top Cooling and Climate Controls Brands for Your Lexus IS350

Our inventory holds Cooling and Climate Controls for your Lexus IS350 from 11 trusted brands. You’ll find OEM and aftermarket parts from brands like Carquest Premium, FELPRO, and Factory Air, all of which can keep that Lexus happy.

Top-Rated Carquest Premium Cooling and Climate Controls

Leading Carquest Premium Cooling and Climate Controls

We carry Carquest Premium brand parts for your Lexus IS350 across several catalog categories, including Engine Cooling Parts and Air Conditioning Parts. Some of our most reviewed Carquest Premium parts include:
Radiator Cap: 16 PSI
from $16.99
(137)
Radiator Cap: 16 PSI
Coolant Reservoir Caps
A/C Desiccant Bag Kit
from $43.99
(7)
A/C Desiccant Bag Kit
AC Receiver Drier Desiccant Elements
Engine Water Pump: New, Gasket/Seals Included
from $89.99
(6)
Engine Water Pump: New, Gasket/Seals Included
Water Pumps

FAQs for Lexus IS350 Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the Lexus IS350?

Out of 69 Cooling and Climate Controls for the Lexus IS350, the most popular in our inventory are:
Cap & Valve A/C System Seal Kit
from $21.99
(29)
Cap & Valve A/C System Seal Kit
AC Caps and Valve Core Kits
Multi-Purpose Relay
from $17.99
This product is not rated
Multi-Purpose Relay
Air Conditioning Relays
Multi-Purpose Relay
from $20.99
This product is not rated
Multi-Purpose Relay
AC Compressor Cut-Out Relays

What are the top-rated Lexus IS350 Cooling and Climate Controls?

Top-rated Cooling and Climate Controls for your Lexus IS350 based on customer reviews/ratings are:
Coolant Temp Sensor Switch
from $34.05
(6)
Coolant Temp Sensor Switch
“Installed this product and engine light went off”
Engine Coolant Reservoir Cap
from $10.99
(4)
Engine Coolant Reservoir Cap
“I had a difficult time finding a coolant reservoir cap for a Toyota Prius. Advance was the only place in town that carried them.”
A/C Plate and Fin Evaporator
from $118.99
(3)
A/C Plate and Fin Evaporator
“At first glance this looks like a perfect match for the stock AC evaporator on my 2016 F-type. The website said it was an exact fit so I ordered it an”