2022 Lexus IS350 Cooling and Climate Controls

Essential 2022 Lexus IS350 Cooling and Climate Controls

Carquest Premium – AC Pressure Sensor (Part No.ACA1745)

AC Pressure Sensor

from

$83.99
The Premium CarQuest Vehicle Solutions line of vehicle electronics are designed for OE form, fit and function for both import and domestic vehicles. The A/C Pressure Sensor reports system pressures to the on-board computer, in turn allowing the computer to properly and efficiently control the compressor, fans and system levels. An improperly functioning A/C Pressure Sensor will provide erratic or inaccurate readings to on-board computers severely affecting system performance and function. Without reliable and accurate data from a properly functioning A/C Pressure Sensor, on-board computers are unable to protect the safety of critical components and the system as a whole which can lead to excessive wear and tear on critical components and costly system damage.

Product Features:
  • Designed and manufactured with high quality materials, industry leading electronic components and strict quality controls. Engineered to exceed OE performance and to meet the uncompromising demands of service professionals.
  • Direct fit replacement matches proper OE fit, form, and function and ensures trouble free installation of your A/C Pressure Sensor.
  • All units are helium leak tested on fully automated mass spectrometer equipment before end-of-line testing.
  • All units are tested using automated end-of-line testing equipment that pressurizes the A/C Pressure Sensor and checks full-spectrum functionality and electrical output to ensure each A/C Pressure Sensor meets manufacturing specifications before packaging
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Carquest Premium – Blower Motor: With Wheel (Part No.76501)

Blower Motor: With Wheel

from

$161.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
  • Functionally Equivalent to OE Design
  • Each unit is 100% tested for functional performance and operational noise
  • Hermetically Sealed & Thermally Protected Electronics
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Carquest Premium – Blower Motor: With Wheel (Part No.76526)

Blower Motor: With Wheel

from

$429.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM. Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
  • Functionally Equivalent to OE Design
  • Magnetic size and properties compare or exceed OEM
  • Hermetically Sealed & Thermally Protected Electronics
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DENSO – First Time Fit Relay (Part No.P2020377199ND)

First Time Fit Relay

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$15.31
An electrical relay is sort of a magical device: it takes a small electrical signal and uses it to manage a much more powerful current, permitting electrical systems to be both lighter and more dependable at the same time. DENSO has supplied quality relays to the OE automotive world for over 60 years. The very same performance and dependability are available across the replacement aftermarket with DENSO First Time Fit® relays. Engineered to meet the most stringent automaker standards for shock resistance, arcing, and thermal protection, DENSO auto relays feature the lowest return rates in the industry; that equals value for car owners and repair facilities alike

Product Features:
  • Lead-free, solderless construction prevents heat shock and arcing
  • Controlled contact force, self-adjusting air gap increase longevity of the internal parts
  • Industry-standard packaging and footprint
  • Low heat generation
  • Reduced electrical loads
  • Built to last
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Dorman – OE Solutions Auxiliary Cooling Fan Assembly (Part No.G5000829557DOR)

OE Solutions Auxiliary Cooling Fan Assembly

from

$309.03
Save time, money and labor with Dorman’s Engine Cooling Fan Assembly. It comes ready to install with the motor, shroud, and blade. Plus, the high fiberglass content offers extra strength and rigidity while improving thermal stability.

Product Features:
  • Optimal air flow prevents vehicle from overheating
  • Plug and Play jumper harnesses included (where applicable)
  • Direct replacement for a proper fit every time
  • All motors are tested prior to final packaging of fan assembly
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Dorman – Radiator Fan Assembly: Dual, Cost Effective & Reliable (Part No.620-498)

Radiator Fan Assembly: Dual, Cost Effective & Reliable

from

$393.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
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Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)

Engine Coolant Reservoir Cap

from

$9.49
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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AISIN – OE Replacement Water Pump (Part No.G3000374992ASC)

OE Replacement Water Pump

from

$210.39
The AISIN Water Pump contains no remanufactured parts and provides optimal cooling without creating excess load to the engine. The highest quality materials are used, creating stronger body design and resistance to corrosion.

Product Features:
  • OE-Equivalent and direct fit application.
  • 100% new with no remanufactured parts.
  • Advanced technological design.
  • Carbon ceramic sealing.
  • Resistant to corrosion.
  • Optimum cooling performance and longevity.
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Carquest Premium – Engine Water Pump: New, Gasket/Seals Included (Part No.T5105)

Engine Water Pump: New, Gasket/Seals Included

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$92.99
Carquest Premium water pumps are 100% new, high-quality parts that meet or exceed original equipment (O.E.) specifications. All components, including the housing, hub, bearings, gaskets and seals are designed for long-lasting service life. These water pumps are supplied with the gaskets or seals necessary for installation. Our Carquest Premium water pumps undergo stringent testing to ensure superior performance that we stand behind with an industry-leading warranty.

Product Features:
  • 100% tested for reliable performance
  • Durable housing features precisely machined mounting surface for proper sealing and fitment
  • Equipped with weep chamber or similar feature to help prevent unnecessary replacement
  • Included heavy-duty unitized bearings, pressed-on hubs and optimal impeller clearance for a long-lasting water pump
  • All gaskets or seals necessary for water pump are included
  • This pump is driven by the accessory belt and we recommend replacement if nearing service recommendation
  • This pump is driven by the timing chain; see vehicle manufacturer recommendation for replacement of timing components
  • This pump is driven by the timing belt; see vehicle manufacturer recommendation for replacement of timing components
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KAI – A/C Desiccant Element (Part No.ARD010152)

A/C Desiccant Element

from

$9.99
New Standard Replacement A/C Receiver Drier/Desiccant Element

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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KAI – A/C Desiccant Element (Part No.ACM010005)

A/C Desiccant Element

from

$16.99
New Standard Replacement A/C Receiver Drier And Desiccant Element

Product Features:
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – A/C Desiccant Bag Kit (Part No.T83029)

A/C Desiccant Bag Kit

from

$38.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:
  • All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
  • Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
  • All accumulators and receiver driers are helium leak tested prior to packaging.
  • O-Rings necessary for installation are included.
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Santech – A/C Pressure Switch (Part No.R1054261110SII)

A/C Pressure Switch

from

$41.24
A/C Pressure Switch

Carquest Premium – Radiator (Part No.813477)

Radiator

from

$163.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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KAI – Radiator (Part No.RAD2968)

Radiator

from

$144.99
New Platinum Pro Radiator, 2.5 And 3.5 Liter Engines, Automatic Transmission

Product Features:
  • 2.5 And 3.5 Liter Engines, Automatic Transmission, Made Of Plastic and Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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DENSO – Radiator (Part No.G1000688282ND)

Radiator

from

$201.73
DENSO is a leading supplier of radiators to OE car makers around the world. Manufacturers rely on our quality and innovation to remain on the leading edge of engine cooling technology. Our OE experience and know-how ensure our products provide unmatched performance, reliability and fitment. Radiator performance is essential for proper engine cooling and function. DENSO’s radiator configurations, tanks, fin pitch, core dimensions and materials meet OE manufacturer’s rigid standards. All DENSO radiators pass our strict durability and function tests. As the result, our radiators deliver reliable performance even under the most demanding conditions. Radiator types: Plastic tank with aluminum core. Plastic tank with copper core. Cross-flow and down-flow configurations. DENSO is known for the unsurpassed quality of its products. Plastic, copper or aluminum components: it doesn’t matter. Our DENSO radiators are dependable, lightweight and made to last. An investment in a DENSO radiator will pay dividends in the long run. Radiators can fail causing leaks or inefficient cooling. This can lead to your engine to run hotter which in turn creates excess wear and tear on the engine. DENSO radiators are designed with our First Time Fit® philosophy in mind. You get radiators that drop in easily without the need for adjustment, brackets or modification of any kind. Our radiators are precision built to provide the right part, the right fit, the first time.

Product Features:
  • Fin Pitch – Superior fin waves provide a higher heat transfer.
  • Flow Configuration – Available in cross-flow and down-flow configurations.
  • Aluminum or Copper Core – Thin-tube construction assures maximum cooling efficiency.
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Carquest Premium – Radiator (Part No.812968)

Radiator

from

$231.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineered with integrated ribbing for added strength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
  • Oil cooler designs meet or exceed OE standards, keeping the vehicle’s engine and transmission performing at optimal conditions
  • OEM grade, premium fittings for transmission or engine oil coolers (where applicable)
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DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)

Engine Coolant Temperature Sensor

from

$82.99
DENSO’s engine coolant temperatures sensors are manufactured to the stricktest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.

Product Features:
  • OE technology adapted for the aftermarket
  • Reduces emissions, increased performance
  • Delivers the highest reliability and detection accuracyá
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Factory Air – Coolant Temp Sensor Switch (Part No.36424)

Coolant Temp Sensor Switch

from

$34.05
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Brass construction for accurate temperature sensing
  • Color coded for easy identification
  • Zinc coated terminal to resist corrosion
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Sankei Switches – Engine Coolant Temperature Sensor (Part No.C6020243726SAK)

Engine Coolant Temperature Sensor

from

$26.92
The Sankei Switches Engine Coolant Temperature Sensor is a high quality Original Equipment replacement that is manufactured to meet or exceed OE specifications for fit, form, and function.

Product Features:
  • Premium Original Equipment replacement
  • Provides performance and dependability
  • Manufactured to meet OE specifications
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Carquest Premium – Coolant Temperature Sensor with O-Ring (Part No.WTC2071)

Coolant Temperature Sensor with O-Ring

from

$8.99
Approved materials for increased durability in even the most extreme temperatures. All MotoRad Coolant Temperature Sensors are designed to meet or exceed OEM specifications at our ISO TS16949 manufacturing facilities.

Product Features:
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • Thread Sealant and/or O-ring pre-installed on applicable sensors to ensure leak free performance
  • Brass sensor housing precision machined to meet or exceed OE thermal conductivity
  • OE precision matched thermistor position for correct output parameters
  • Extensive product testing includes salt spray, high/low temperature impact, thermal vibration, durability, static electricity, and micro tension, among other tests, to ensure all sensors meet or exceed OEM specifications.
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DENSO – New Compressor With Clutch (Part No.471-1569)

New Compressor With Clutch

from

$582.99
As one of the world+s largest OE suppliers of A/C compressors DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO+s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:
  • DENSO is the world’s largest OE supplier of A/C compressors
  • Each compressor is precision manufactured for exact replacement
  • Designed for high output and extended durability
  • Highest quality in the Aftermarket
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Carquest Premium – New Compressor with Clutch, Nippondenso 7SAS17C (Part No.T168348)

New Compressor with Clutch, Nippondenso 7SAS17C

from

$465.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Endurance tested the equivalent of 50k miles
  • Includes specific electrical connector to eliminate splicing
  • Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
  • For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
  • Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
  • New Compressors meet or exceed OE specifications
  • New Compressors are validated for the equivalent of 100,000 miles
  • New Compressors come pre-charged with 3 ounces of PAG oil for R134a or R1234yf applications
  • New Compressors come with direct fit connectors for ease of installation and to help eliminate splicing
  • New Compressors come with the R12/R134A/1234yf required o-rings /sealing washers to install the compressor
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KAI – A/C Compressor (Part No.ACP012364)

A/C Compressor

from

$474.99
New Standard Replacement A/C Compressor, 6 Groove, V6 Engine

Product Features:
  • 6 Groove, V6 Engine
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – A/C New; w/ Clutch; w/ 6SBU16C Compressor (Part No.T158348)

A/C New; w/ Clutch; w/ 6SBU16C Compressor

from

$752.99
Carquest New Compressors are designed, manufactured and tested to meet or exceed strict original equipment specifications for superior quality and performance. Each new compressor is tested to provide durable life to the vehicle’s air conditioning system. All new compressor components are assembled using state of the art equipment and techniques to ensure smooth operation. Each part is equipped with a clutch and connector that matches the original equipment part and provides an exact replacement to your vehicle’s part. All compressors are supplied with the necessary gaskets and o-rings for installation.

Product Features:
  • Each new compressor design undergoes rigorous life cycle testing at high RPMs and pressures to ensure that they can withstand years in the harshest conditions.
  • New compressors are designed with utmost precision using 3D coordinate measuring machines to ensure a perfect fit.
  • The production process contains automated controls at every stage that alerts and halts production in case of an error, assuring that the finished product will always be flawless.
  • All new compressors must pass a helium leak test and pump up function test prior to packaging.
  • O-Rings and gaskets necessary for installation are included.
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Carquest Premium – New Compressor with Clutch, Nippondenso 7SAS17C (Part No.T168347)

New Compressor with Clutch, Nippondenso 7SAS17C

from

$510.99
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Endurance tested the equivalent of 50k miles
  • Includes specific electrical connector to eliminate splicing
  • Charged with lubricant to reduce internal friction promoting enhanced system performance and longevity
  • For ease of installation this compressor includes a direct fit OE style connector as well as all gaskets, O-rings, or seals needed to repair your car
  • Each unit is individually leak, vacuum and pressure tested prior to packaging to ensure leak free performance
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DENSO – New Compressor With Clutch (Part No.471-1568)

New Compressor With Clutch

from

$595.99
As one of the world+s largest OE suppliers of A/C compressors DENSO units are specified by most major vehicle manufacturers. DENSO First Time Fit A/C compressors are manufactured and tested to the strictest OE standards for unparalleled performance. At DENSO we bring together everything we know as an air conditioning systems manufacturer to bring you the highest quality line of factory-new compressors available. When it comes to new compressors you can’t do better than going with a unit manufactured by the OE supplier. At DENSO we know these units better than anyone because we originally designed them. Our compressors are built to meet DENSO+s unsurpassed reputation for technological superiority. You can relax knowing DENSO will give you the right part and the right fit the first time.

Product Features:
  • DENSO is the world’s largest OE supplier of A/C compressors
  • Each compressor is precision manufactured for exact replacement
  • Designed for high output and extended durability
  • Highest quality in the Aftermarket
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Carquest Premium – New Compressor (Part No.T168367)

New Compressor

from

$462.99
Carquest Premium A/C compressors are 100% new units that are manufactured to the highest quality to meet or exceed OE specifications.

Product Features:
  • Every unit is 100% function and leak tested
  • Tested for noise, vibration, durability, vacuum decay and pressure decay to ensure no leaks and longer life
  • Very low friction coating used on swash plate to improve durability
  • PTFE coated pistons improve performance and reduce wear
  • Rubber dampened clutch plate ensures smooth clutch engagement and reduces wear
  • Matched high-quality needle-roller bearing ensures low friction and high load capability
  • Limited Lifetime Warranty when following warranty requirements: Flush A/C System, replace accumulator/receiver dryer, replace orifice tube/expansion device, and filling with correct oil and refrigerant
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2022 Lexus IS350 Cooling and Climate Controls

You count on your 2022 Lexus IS350 to run right. That means taking care of it with regular maintenance, necessary repairs, and the right parts. Advance Auto Parts can help with all of that thanks to our extensive inventory of trusted Cooling and Climate Controls. With 14 Cooling and Climate Controls ranging in price from $8.99 to $510.99, you’re sure to find everything you need for your 2022 Lexus IS350.

Brands matter. If you want to shop a specific Cooling and Climate Controls brand, we stock 6 different brands like Carquest Premium, Original Equipment, and Aisan. 2022 Lexus IS350 Cooling and Climate Controls start as low as $8.99!

One of the best ways to find top quality OEM or aftermarket Cooling and Climate Controls is by asking professionals. Short of that, you can shop with confidence thanks to our 4 extensive product reviews on 2022 Lexus IS350 Cooling and Climate Controls.

Did we mention you can order your Cooling and Climate Controls from our online catalog and have them shipped right to your garage? Or, if you feel like seeing the parts first-hand, search for your nearest Advance Auto Parts location above and pick up in-store when you’re ready. Browse our full Cooling and Climate Controls inventory for your 2022 Lexus IS350 below to get started!

Top-Rated Cooling and Climate Controls Brands For Your 2022 Lexus IS350

Trusted Cooling and Climate Controls OEM and aftermarket product brands are what Advance Auto Parts specializes in. The brands we work with are sure to keep that 2022 Lexus IS350 running right for years to come. In our inventory you’ll find brands like Carquest Premium, Original Equipment, Aisan, and even more.

Popular Carquest Premium Cooling and Climate Controls

You’ll find popular Carquest Premium brand products across Engine Cooling Parts. All are waiting to get your 2022 Lexus IS350 back on the road. Some of the top-rated Carquest Premium products in these categories are:
Engine Coolant Reservoir Cap
from $9.49
(4)
Engine Coolant Reservoir Cap
Coolant Reservoir Caps

FAQs for 2022 Lexus IS350 Cooling and Climate Controls

What are the most purchased Cooling and Climate Controls for the 2022 Lexus IS350?

Out of 14 Cooling and Climate Controls for the 2022 Lexus IS350, the most popular in our inventory are:
Expansion Tank Cap
from $15.27
This product is not rated
Expansion Tank Cap
Coolant Reservoir Caps
AC Pressure Sensor
from $83.99
This product is not rated
AC Pressure Sensor
AC Refrigerant Pressure Sensors
A/C Pressure Switch
from $41.24
This product is not rated
A/C Pressure Switch
AC High Pressure Side Switches