GMC Sierra 2500 HD Fluids

Your One-Stop Shop For Trusted GMC Sierra 2500 HD Fluids

If you’re in search of GMC Sierra 2500 HD Fluids aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 63 Fluids from top brands with prices ranging from $1.45 to $1,221.99.

Beyond great prices, we stock trusted brands manufacturing all types of Fluids for your GMC Sierra 2500 HD.

And don’t forget to read customer reviews across all Fluids categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Fluids have to cost top dollar, and we prove it. Browse our top GMC Sierra 2500 HD Fluids below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

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Essential GMC Sierra 2500 HD Fluids

Prestone – Prestone MAX DOT 3 Brake Fluid: 12 oz., AS415 (Part No.AS415)

Prestone MAX DOT 3 Brake Fluid: 12 oz., AS415

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$6.99
Prestone® DOT 3 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards, benefitting all vehicles calling for DOT 3. This synthetic fluid starts with a higher dry boiling point than the DOT minimum standard to protect against overheating, brake fade and performance decline due to water absorption. This extended life (50,000 mile) fluid is also formulated to prevent corrosion of all metals within the braking system. This formula is safe to use in all DOT 3 braking systems (ABS, disc or drum) and can mix with any DOT 3 fluid. It is recommended to only use the DOT fluid specified for your car, as using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.
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Prestone – Prestone DOT 5.1 Brake Fluid: Synthetic, High Grade, High Performance Formula For Extreme Braking, 12 oz., AS820-6 (Part No.AS820-6)

Prestone DOT 5.1 Brake Fluid: Synthetic, High Grade, High Performance Formula For Extreme Braking, 12 oz., AS820-6

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$18.99
Prestone DOT 5.1 Motor Vehicle Brake Fluid delivers enhanced performance vs. DOT standards and is designed to handle the most extreme braking situations. Prestone DOT 5.1 is a high performance formula for extreme braking situations like racing. Formulated to protect against overheating and brake fade with a formula that exceeds DOT standards. This synthetic extended life fluid starts with higher dry boiling point vs. DOT standard protecting against performance decline due to water absorption. This formula is safe to use in all DOT 5.1 braking systems, ABS, disc or drum, and can mix with any DOT 5.1 fluid. It is recommended to only use the DOT fluid specified for your car. Using a different DOT product can affect the boiling point or replacement interval if the wrong fluid is used.
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Valvoline – Valvoline DEXRON – VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 822405 (Part No.822405)

Valvoline DEXRON - VI ATF Full Synthetic Automatic Transmission Fluid, 1 Quart, 822405

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$15.99
Valvoline DEXRON-VI/MERCON LV ATF is a full-synthetic transmission fluid formulated with advanced additive technology to meet and exceed the requirements of the General Motors DEXRON-VI specification. It is officially licensed and approved by GM and is fully back-serviceable and can be used wherever DEXRON-II and/or DEXRON-III are recommended. Recommended for use in the following applications: DEXRON-VI, DEXRON-III, DEXRON-II, and Allison C-4. Volume: 1 quart.
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Valvoline – Valvoline DEX/MERC ATF Conventional Automatic Transmission Fluid, 1 Quart, 798153 (Part No.798153)

Valvoline DEX/MERC ATF Conventional Automatic Transmission Fluid, 1 Quart, 798153

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$10.99
Valvoline DEX/MERC ATF is a high-quality transmission fluid formulated to meet the challenging demands of many automatic transmissions. Its responsive low-temperature fluidity is beneficial in both electronic and hydraulic controlled transmissions and transaxles. Recommended for use in the following applications: MERCON*, DEXRON*-III, Ford M2C138-CJ and M2C166-H, Allison C-4 and TES-389, and Caterpillar TO-2. Volume: 1 quart.
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Valvoline – Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775 (Part No.773775)

Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon, 773775

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$39.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life. Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Volume: 1 gallon.
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Valvoline – Valvoline TRANSFER CASE FLUID 6/1 QT, 855459 (Part No.855459)

Valvoline TRANSFER CASE FLUID 6/1 QT, 855459

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$15.99
Valvoline Multi-Vehicle Transfer Case Fluid is a full synthetic product meeting the performance needs for transfer cases recommending Ford XL-12 and GM Auto Trak II specifications or ATF fluids (DEX/MERC, ATF +4, etc).
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Valvoline – Valvoline Flex 75W90 Extended Protection Synthetic Gear Oil, Quart, 902146 (Part No.902146)

Valvoline Flex 75W90 Extended Protection Synthetic Gear Oil, Quart, 902146

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$23.99
You asked, we listened. DIYers said they wanted a premium gear oil in an easy-to-use package. Valvoline delivered with Extended Protection Flexfill Full Synthetic Gear Oil, providing up to 4X better gear wear protection than our conventional formulation. Unlike the industry-leading premium gear oil, Valvoline Extended Protection Flexfill Gear Oil features an innovative flexible pouch for reaching tight, hard-to-reach spaces with less waste. The high-performance formula combines superior-quality synthetic base stocks and additives for outstanding high and low temperature protection and superb thermal stability in demanding environments like towing, hauling or off-roading. So no matter where the road takes you, Valvoline Extended Protection Gear Oil is proven to maximize gear life. Our additive technology delivers extreme pressure protection, better load carrying capacity and wear resistance, plus excellent corrosion protection, while the anti-foaming agent improves lubrication for quieter, smooth-running gears. Now, Valvoline offers the best of both gear oil worlds: A premium full synthetic product in the preferred Flex fill package. No waste, no mess, no cone-shaped containers. Only from Valvoline €“ the #1 gear oil brand. Available in SAE 75W-90 and SAE 75W-140.
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Valvoline – Valvoline MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart, 904857 (Part No.904857)

Valvoline MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Quart, 904857

from

$13.99
Valvoline Full Synthetic MaxLife Multi-Vehicle ATF, the No. 1 ATF product, suitable for use in millions of vehicles. Featuring advanced additives to prevent the major causes of transmission breakdown, it’s designed to help prevent leaks, reduce wear & tear, and maximize performance. Has improved thermal stability for longer fluid life, better viscosity stability for consistent transmission operation, and frictional enhancements for smooth gear engagements. Valv MaxLife Multi-Vehicle ATF is recommended for use in: GM DEXRON-II, DEXRON-III, DEXRON-VI; Ford MERCON LV; and JASO M315-2013 1A-LV. Volume: 1 quart.
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Valvoline – Valvoline Restore & Protect Automatic Transmission Fluid 1 Ga, 913033 (Part No.913033)

Valvoline Restore & Protect Automatic Transmission Fluid 1 Ga, 913033

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$37.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.
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Prestone – Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Original Equipment North American Orange, 1 Gallon, AF6700 (Part No.AF6700)

Prestone Antifreeze & Coolant: 50/50 Ready-to-Use, Original Equipment North American Orange, 1 Gallon, AF6700

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$22.99
Prestone American Vehicles (Orange) antifreeze+coolant is specially designed to work with these specific vehicles: Ford 2002 and newer; Chrysler 2000 and newer; GM 1995 and newer. Prestone’s Antifreeze+Coolants are designed to the highest standards using state of the art technology. These fluids are designed to not only manage the engine temp and protect from freezing up, but they also protect the engine from rust, corrosion, buildup, pitting and engine damage. All of those can cause engine part failure and expensive repairs. Avoid costly repairs and vehicles in the shop with Prestone Asian vehicles antifreeze+coolant. This fluid is designed to last 10yrs / 300,000 miles and also to protect the internal parts of the engine for 10yrs / 300,000, officially patented by Prestone. Volume: 1 gallon.
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Valvoline – Valvoline MaxLife 5W-30 Synthetic Blend Motor Oil, Extends Engine Life, 5 Gallon, 881047 (Part No.881047)

Valvoline MaxLife 5W-30 Synthetic Blend Motor Oil, Extends Engine Life, 5 Gallon, 881047

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$154.99
If you have over 75,000 miles, you need the superior protection of America’s first high mileage Motor Oil. Valvoline High Mileage MaxLife helps extend the life of your vehicle by fighting the four major signs of engine wear – reduced power, loss of fuel economy, oil leaks and increased oil consumption. The synthetic blend formula contains extra additives designed to combat these problems unique to aging cars and trucks. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition. Volume: 5 gallons.
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Shell – Shell T6 15W-40 Full Synthetic Diesel Engine Oil, Protects Against Wear, 1 Gallon, 550050467 (Part No.550050467)

Shell T6 15W-40 Full Synthetic Diesel Engine Oil, Protects Against Wear, 1 Gallon, 550050467

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$41.99
Shell Rotella T6 15W-40 diesel engine oil is a full synthetic motor oil that features exclusive Triple Protection Plus technology, formulated with fully synthetic base oils plus advanced additives to protect against wear, deposits, and oil breakdown. It offers better cold cranking properties and low-temperature pumpability at -15C compared to conventional and synthetic blend Shell Rotella 15W-40 products. It also delivers improved wear performance versus API CJ-4 technology, extended drain capabilities for more uptime, improved protection against oxidation for increased fuel economy, compatibility with exhaust emissions control systems, and protection in extreme operating conditions and climates. Shell Rotella T6 15W-40 is suitable for use in new and older diesel-powered vehicles, from Class 8 tractor/trailers to heavy-duty pickups and delivery, utility, and school bus fleets. Shell Rotella T6 is backed by a limited warranty valid up to 15 years or 500,000 miles (whichever comes first), guaranteed. (Shell Rotella Limited Warranty: Up to 15 years or 500,000 miles, whichever comes first, guaranteed, if you exclusively use Shell Rotella T6 Full Synthetic heavy-duty engine oil and meet enrollment mileage and vehicle manufacture date requirements. Enrollment required. Keep your receipts. Other conditions apply. See Rotella.com/warranty to enroll and for full details and terms.) Volume: 1 gallon.
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Royal Purple – Royal Purple High Performance 5W-30 Synthetic Engine Oil, Better Wear Protection, 5 Quart, 51530 (Part No.51530)

Royal Purple High Performance 5W-30 Synthetic Engine Oil, Better Wear Protection, 5 Quart, 51530

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$49.99
Royal Purple Motor Oil is a specially formulated multi viscocity oil for use in gasoline and diesel engines of all types from cars and trucks to SUVs, motorcycles and boats. Royal Purple(R) Motor Oil with Synerlec(R) additive technology reduces friction, which results in a 1-3 percent increase in horsepower, lowers operating temperatures, provides superior corrosion protection, improves fuel economy, reduces emissions and extends oil life. A.P.I. Certified. Volume: 5 quarts.
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Lube Gard – Lube Gard Complete Synthetic Power Steering Fluid Multi-Vehicle Formula, 32 oz., 23232 (Part No.23232)

Lube Gard Complete Synthetic Power Steering Fluid Multi-Vehicle Formula, 32 oz., 23232

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$21.49
Complete Synthetic Power Steering Fluid formulated for use in American, European and Asian Vehicels. Electric Power Steering Fluid Compatible.
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Valvoline – Valvoline High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart, VV820 (Part No.VV820)

Valvoline High Performance Transmission & Differential Gear Oil: Conventional 75W-90, 1 Quart, VV820

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$13.99
Valvoline High Performance Synthetic Gear Oil is the thermally stabile extreme pressure lubricant that offers outstanding protection for gearboxes and differentials in passenger cars, light trucks, and sport utility vehicles. Combined with high quality synthetic base oils, our formula’s superior additives help reliably safeguard against severe temperatures, shock loads, foaming, scuffing, scouring, corrosion and pitting in high load, high torque and high horsepower conditions. Can be used in conventional and limited slip hypoid differentials where GL-5 is specified as well as non-synchronized manual transmissions that require GL-4. Protect your gears with Valvoline, the #1 gear oil brand. Volume: 1 quart.
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Royal Purple – Royal Purple Max Performance Synthetic Power Steering Fluid, 01326 (Part No.01326)

Royal Purple Max Performance Synthetic Power Steering Fluid, 01326

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$6.99
Royal Purple Max Performance Synthetic Power Steering Fluid, 01326.
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Prestone – Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz., AS263Y (Part No.AS263Y)

Prestone Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz., AS263Y

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$15.99
Prestone Power Steering Fluid + Stop Leak (PSF+SL) delivers increased system life and prevents & stops system leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. The stop leak additives also prevent leaks by rejuvenating seals before they leak. Also designed with Anti-wear System Protection, Prestone PSF+SL protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.
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FRAM – FRAM DEF (Diesel Exhaust Fluid), API Certified,2.5 Gallon, 457 (Part No.457)

FRAM DEF (Diesel Exhaust Fluid), API Certified,2.5 Gallon, 457

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$14.99
Maximize your diesel engine’s efficiency and reduce emissions with FRAM Diesel Exhaust Fluid (DEF). Made with high-purity synthetic urea and deionized water, FRAM DEF is designed for compatibility with Selective Catalytic Reduction (SCR) systems. Volume: 5 gallons.
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PEAK – PEAK BlueDEF Diesel Exhaust Fluid, Triple-Filtered and Guaranteed Pure, 2.5 Gallon, DEF002 (Part No.DEF002)

PEAK BlueDEF Diesel Exhaust Fluid, Triple-Filtered and Guaranteed Pure, 2.5 Gallon, DEF002

from

$22.99
PEAK BlueDEF Diesel Exhaust Fluid is a mixture of high purity synthetic urea and deionized water that is used in Selective Catalytic Reduction (SCR) systems in diesel vehicles. DEF is used to help convert NOx to harmless nitrogen and water. Volume: 5 gallons.
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BlueDEF – BlueDEF PLATINUM Diesel Exhaust Fluid, Prevents SCR System Deposits, 2.5 Gallon, DEG002 (Part No.DEG002)

BlueDEF PLATINUM Diesel Exhaust Fluid, Prevents SCR System Deposits, 2.5 Gallon, DEG002

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$28.99
PEAK BlueDEF PLATINUM with advanced SYSTEM SHIELD technology is a groundbreaking premium Diesel Exhaust Fluid with a proprietary formula to tackle deposits that can build up in the SCR system. Volume: 5 gallons.
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Castrol – Castrol Autran Syn-295 Synthetic Transmission Fluid, 1 Gallon, 709732 (Part No.709732)

Castrol Autran Syn-295 Synthetic Transmission Fluid, 1 Gallon, 709732

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$71.99
Autran Syn-295 Synthetic Transmission Fluid is a premium full-synthetic solution designed for heavy-duty automatic transmissions, meeting the rigorous Allison TES-295 and TES-468 standards. Engineered with high-viscosity index synthetic base fluids and advanced additives, it delivers exceptional wear protection, superior high and low-temperature performance, and outstanding shear stability. This fluid keeps transmissions cooler, resists oxidation, and offers excellent corrosion and foaming resistance, ensuring long-lasting reliability even under extreme operating conditions. Compatible with a wide range of OEM systems, including Allison C-4, Voith, and ZF transmissions, it is ideal for light-duty applications such as buses, emergency vehicles, delivery trucks, motor homes, and more. Whether for on- or off-highway use, this 1-gallon solution provides unmatched durability and performance, making it a trusted choice for demanding environments. Volume: 1 gallon.
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Fluids Brands You Can Trust For Your GMC Sierra 2500 HD

14 trusted brands of Fluids line our shelves, ready to help keep your GMC Sierra 2500 HD running smooth. Below are some of the most popular brands and their top Fluids offerings:

Top GMC Sierra 2500 HD Fluids from Mobil 1

Your GMC Sierra 2500 HD will be purring again thanks to Mobil 1 brand Fluids available for online order or in-store pick up. Popular Mobil 1 parts include:

Most Purchased GMC Sierra 2500 HD Fluids from Valvoline

When you buy the most frequently purchased Valvoline brand Fluids, you can be confident it will be the right part for your GMC Sierra 2500 HD. Here are the Valvoline Fluids Advanced Auto customers buy the most:

FAQs for GMC Sierra 2500 HD Fluids

What are the most purchased Fluids for the GMC Sierra 2500 HD?

Out of 63 Fluids for the GMC Sierra 2500 HD, the most popular in our inventory are:
PEAK BlueDEF Diesel Exhaust Fluid, Triple-Filtered and Guaranteed Pure, 2.5 Gallon, DEF002
from $22.99
This product is not rated
PEAK BlueDEF Diesel Exhaust Fluid, Triple-Filtered and Guaranteed Pure, 2.5 Gallon, DEF002
Diesel Emissions Fluids

What are the top-rated GMC Sierra 2500 HD Fluids?

Top-rated Fluids for your GMC Sierra 2500 HD based on customer reviews/ratings are: