Ford F-350 Pickup Spark Plugs

Your One-Stop Shop For Trusted Ford F-350 Pickup Spark Plugs

If you’re in search of Ford F-350 Pickup Spark Plugs aftermarket or OEM parts, consider your search over! Advance Auto Parts carries 96 Spark Plugs from top brands with prices ranging from $1.25 to $67.49.

Beyond great prices, we stock trusted brands manufacturing all types of Spark Plugs for your Ford F-350 Pickup.

And don’t forget to read customer reviews across all Spark Plugs categories in our catalog. Buy with confidence by leveraging past customer experiences of our aftermarket and OEM parts.

At Advance Auto Parts, we don’t think top quality Spark Plugs have to cost top dollar, and we prove it. Browse our top Ford F-350 Pickup Spark Plugs below, order online to ship to your home, or head into your nearest Advance Auto Parts location to get started.

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Essential Ford F-350 Pickup Spark Plugs

Autolite – Autolite Racing Resistor Spark Plug: Enhanced Heat Transfer for Peak Performance, AR25 (Part No.AR25)

Autolite Racing Resistor Spark Plug: Enhanced Heat Transfer for Peak Performance, AR25

from

$4.99
Racing Resistor Spark Plug is expertly crafted to deliver peak performance in competitive racing environments. Featuring a cut-back ground electrode, it ensures optimal ignitability and superior heat transfer for quicker starts and maximum engine efficiency. The yttrium-enhanced alloy reduces ground wire temperature by up to 8%, making it ideal for colder heat ranges and performance modifications. Its anti-corrosive nickel plating resists rust better than black oxide, ensuring long-lasting durability. Designed with a high alumina multi-rib ceramic insulator, it offers exceptional thermal conductivity and insulation, preventing flash-over and enhancing strength. The tapered seat type optimizes performance across various racing venues, from oval tracks to road circuits. Built to withstand intense conditions, this spark plug is compatible with all aftermarket cylinder heads used in competitive racing. With a mid-projection center electrode and nickel tip materials, it combines reliability and efficiency, making it a top choice for racers seeking consistent, high-performance ignition.
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Dorman – Help – Dorman – Help Spark Plug Non-Foulers – 14mm Tapered Seat, 42006 (Part No.42006)

Dorman - Help Spark Plug Non-Foulers - 14mm Tapered Seat, 42006

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$8.49
This spark plug non fouler is designed for easy installation on specified vehicles to protect spark plugs from fouling and damage. It is engineered for durability and reliable performance.
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Accel – Accel HP Copper Spark Plug – Shorty – 14mm Thread – .460 in Reach – Tapered Seat – Non-Resistor – 4 Pack, 0276S-4 (Part No.0276S-4)

Accel HP Copper Spark Plug - Shorty - 14mm Thread - .460 in Reach - Tapered Seat - Non-Resistor - 4 Pack, 0276S-4

from

$38.19
ACCEL’s patented race proven spark plugs in a Shorty configuration. The overall length has been reduced 3/16 in to 3/8 in (depending on the specific spark plug) to gain critical air gap between the spark plug boot and the exhaust manifold or header tube. This helps eliminate burning the spark plug boot or dimpling the header tube. The shorter spark plug length also can make it easier to install an remove the spark plugs in certain applications where there is not a lot of room to fit a socket or move a wrench around. ACCEL Shorty Spark Plugs are made with a Copper core which is a better conductor than Platinum and Iridium. They deliver a stronger spark especially in high performance applications where high combustion pressures are present. Copper is much better at dissipating heat than other materials which lessens the chance of a misfire. ACCEL Shorty Spark Plugs are gapable allowing you to open the gap exposing a larger flame kernel or close it if needed for high boost applications. All ACCEL Shorty Spark Plugs have machine rolled threads allowing for a more precise thread engagement and torque retention.
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Autolite – Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 46 (Part No.46)

Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 46

from

$4.79
Autolite Copper spark plugs are designed to deliver reliable performance, ensuring quick starts and the power your vehicle demands. Featuring a copper core center electrode, these spark plugs excel in thermal control and resist fouling, while the high nickel alloy center and ground electrodes provide extended life. The high alumina multi-rib ceramic insulator enhances thermal conductivity and insulation, offering increased strength and durability. With a nickel-plated shell, these spark plugs resist corrosion for long-lasting performance. Engineered for optimal fuel economy, they help improve mileage while delivering smooth and responsive acceleration. Compliant with Original Equipment Service (OES) design Standards, they ensure dependable operation and a secure fit with their tapered seat type. The long projection center electrode and nickel tip materials further enhance their efficiency and reliability, making them a valuable addition to your vehicle’s ignition system.
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Motorcraft – Motorcraft Spark Plug: Enhances Durability & Reduces Fuel Consumption, SP-425 (Part No.SP-425)

Motorcraft Spark Plug: Enhances Durability & Reduces Fuel Consumption, SP-425

from

$2.79
Motorcraft Spark Plugs are original equipment on Ford Motor Company vehicles, engineered to meet strict Ford engineering standards for optimal performance and reliability. These spark plugs are matched to specific engines to provide enhanced durability, eliminate misfires, reduce fuel consumption, and optimize emissions. Resistant to oxidation and arc erosion, they feature a multi-rib insulator to protect against misfires and offer service intervals of up to 100,000 miles. Designed with high-quality materials, Motorcraft Spark Plugs ensure reliable performance for a broad range of applications, including domestic and import cars and trucks of all makes and sizes. Backed by Motorcraft’s Service Parts Warranty, they are an exact fit for Ford, Lincoln, and Mercury vehicles, helping to prevent false check engine lights and providing the same quality as the original components installed during manufacturing.
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Motorcraft – Motorcraft Spark Plug: Quick Starts & Enhanced Fuel Economy, SP-450 (Part No.SP-450)

Motorcraft Spark Plug: Quick Starts & Enhanced Fuel Economy, SP-450

from

$4.79
The Spark Plug: Quick Starts & Enhanced Fuel Economy by Motorcraft is the same high-quality part installed when your engine first rolled off the assembly line, ensuring a perfect fit and reliable performance. Designed and recommended by Ford Motor Company, these spark plugs are engineered to deliver quick starts, improved fuel economy, and smooth acceleration, making them an essential component for maintaining your vehicle’s peak performance. Featuring a tapered seat type, they provide a secure and precise fit, reducing the risk of leaks or misfires. Built to meet the exacting standards of Ford, these spark plugs offer exceptional durability and long-lasting performance, giving you confidence in every drive. Whether you’re replacing worn-out plugs or performing routine maintenance, this part ensures your engine runs efficiently and reliably, offering excellent value for your investment.
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Autolite – Autolite Double Platinum Spark Plug: Enhanced Durability & Performance, APP24 (Part No.APP24)

Autolite Double Platinum Spark Plug: Enhanced Durability & Performance, APP24

from

$7.49
The Double Platinum Spark Plug is engineered for exceptional durability and performance, making it a top choice for distributor-less ignition system (DIS) engines. Featuring a platinum-to-platinum design, it minimizes gap erosion and reduces misfires, ensuring a longer service life compared to copper and standard platinum plugs. Its yttrium-enhanced ground electrode delivers superior heat transfer, allowing it to withstand high temperatures and pressures for extended durability. The high alumina ceramic insulator optimizes thermal conductivity and dielectric strength, while the multi-rib insulator prevents flash-over for reliable operation. With a mid-projection center electrode and tapered seat type, this performance-grade spark plug is built to deliver consistent ignition and efficiency. Both the center and ground electrode tips are crafted from platinum, ensuring superior conductivity and longevity. Designed to meet the demands of modern engines, this spark plug offers unmatched value and reliability for drivers seeking enhanced engine performance.
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Accel – Accel HP Copper Spark Plug – Shorty – 14mm Thread – .460 in Reach – Tapered Seat – 2 pack of 0574S-4, 8198 (Part No.8198)

Accel HP Copper Spark Plug - Shorty - 14mm Thread - .460 in Reach - Tapered Seat - 2 pack of 0574S-4, 8198

from

$67.49
ACCEL’s patented race proven spark plugs in a Shorty configuration. The overall length has been reduced 3/16 in to 3/8 in (depending on the specific spark plug) to gain critical air gap between the spark plug boot and the exhaust manifold or header tube. This helps eliminate burning the spark plug boot or dimpling the header tube. The shorter spark plug length also can make it easier to install an remove the spark plugs in certain applications where there is not a lot of room to fit a socket or move a wrench around. ACCEL Shorty Spark Plugs are made with a Copper core which is a better conductor than Platinum and Iridium. They deliver a stronger spark especially in high performance applications where high combustion pressures are present. Copper is much better at dissipating heat than other materials which lessens the chance of a misfire. ACCEL Shorty Spark Plugs are gapable allowing you to open the gap exposing a larger flame kernel or close it if needed for high boost applications. All ACCEL Shorty Spark Plugs have machine rolled threads allowing for a more precise thread engagement and torque retention.
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Autolite – Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 26 (Part No.26)

Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 26

from

$4.79
Autolite Copper spark plugs are designed to provide reliable performance and durability, making them an excellent choice for maintaining your vehicle’s efficiency. Featuring a copper core center electrode, these spark plugs excel in thermal control and resist fouling, ensuring consistent operation. The high nickel alloy center and ground electrodes are engineered for extended life, while the mid-projection design optimizes spark delivery. A high alumina multi-rib ceramic insulator enhances thermal conductivity and insulation, contributing to superior strength and reliability. The nickel-plated shell offers exceptional corrosion resistance, ensuring long-lasting durability even in demanding conditions. With a tapered seat type and integrated resistor, these spark plugs are built to meet performance expectations, delivering quick starts and the power your vehicle needs.
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Motorcraft – Motorcraft High-Performance Spark Plug: Enhances Fuel Efficiency, SP-420-X (Part No.SP-420-X)

Motorcraft High-Performance Spark Plug: Enhances Fuel Efficiency, SP-420-X

from

$4.99
This high-performance spark plug is meticulously crafted to elevate your engine’s efficiency and reliability. Featuring a standard center electrode design with durable nickel tips for both the center and ground electrodes, it ensures consistent and dependable ignition. Its advanced engineering optimizes combustion, leading to smoother engine performance, improved fuel efficiency, and reduced emissions – perfect for eco-conscious drivers. The tapered seat type enhances its fit and functionality, making it suitable for a wide range of vehicles. Built with precision manufacturing and long-lasting materials, this spark plug is ideal for both daily commutes and high-performance driving, offering exceptional value and durability for your vehicle’s needs.
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Accel – Accel HP Copper Spark Plug – Shorty – 14mm Thread – .460 in Reach – Tapered Seat – 4 Pack, 0574S-4 (Part No.0574S-4)

Accel HP Copper Spark Plug - Shorty - 14mm Thread - .460 in Reach - Tapered Seat - 4 Pack, 0574S-4

from

$49.99
ACCEL’s patented race proven spark plugs in a Shorty configuration. The overall length has been reduced 3/16 in to 3/8 in (depending on the specific spark plug) to gain critical air gap between the spark plug boot and the exhaust manifold or header tube. This helps eliminate burning the spark plug boot or dimpling the header tube. The shorter spark plug length also can make it easier to install an remove the spark plugs in certain applications where there is not a lot of room to fit a socket or move a wrench around. ACCEL Shorty Spark Plugs are made with a Copper core which is a better conductor than Platinum and Iridium. They deliver a stronger spark especially in high performance applications where high combustion pressures are present. Copper is much better at dissipating heat than other materials which lessens the chance of a misfire. ACCEL Shorty Spark Plugs are gapable allowing you to open the gap exposing a larger flame kernel or close it if needed for high boost applications. All ACCEL Shorty Spark Plugs have machine rolled threads allowing for a more precise thread engagement and torque retention.
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Motorcraft – Motorcraft Engineered Spark Plug: Quick Starts & Enhanced Fuel Economy, SP-435 (Part No.SP-435)

Motorcraft Engineered Spark Plug: Quick Starts & Enhanced Fuel Economy, SP-435

from

$4.79
Motorcraft spark plugs are designed, engineered, and recommended by Ford Motor Company. These spark plugs are the same part installed when the engine rolled off the assembly line, ensuring a perfect fit and optimal performance. They are designed to deliver quick starts, enhanced fuel economy, and smooth acceleration, making them an ideal choice for maintaining your vehicle’s efficiency and reliability.
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Autolite – Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 24 (Part No.24)

Autolite Copper Resistor Spark Plug: Quick Starts & Enhanced Durability, 24

from

$4.49
Autolite Copper spark plugs are crafted to deliver reliable performance and quick starts, ensuring your vehicle meets its power and efficiency needs. Featuring a copper core center electrode, these spark plugs excel in thermal control and resist fouling, while the high nickel alloy center and ground electrodes provide extended life and durability. The high alumina multi-rib ceramic insulator enhances thermal conductivity and insulation, offering superior strength under demanding conditions. Designed with a corrosion-resistant nickel-plated shell, these spark plugs are built to last, even in harsh environments. With a mid-projection standard center electrode and tapered seat type, they ensure optimal compatibility and fit. Engineered for good fuel economy, they help optimize fuel efficiency, saving you money over time. Whether for regular-grade applications or vehicles requiring a resistor-type spark plug, Autolite Copper spark plugs deliver dependable performance and value.
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Champion – Champion Copper Plus Small Engine Spark Plug H10C – Dependable Performance & Durability, 844-1 (Part No.844-1)

Champion Copper Plus Small Engine Spark Plug H10C - Dependable Performance & Durability, 844-1

from

$3.29
Champion Copper Plus spark plugs deliver dependable ignition performance with proven copper-core technology. The copper core electrode provides excellent conductivity and optimized heat control for consistent sparks while the coated shell protects against corrosion. Champion your engine with spark plugs engineered to improve efficiency and keep your vehicle running at its best.
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Autolite – Autolite Platinum Spark Plug: Enhanced Durability & Improved Performance, AP25 (Part No.AP25)

Autolite Platinum Spark Plug: Enhanced Durability & Improved Performance, AP25

from

$5.49
The Platinum Spark Plug is engineered for exceptional performance and durability, making it ideal for older engine applications. Featuring a platinum center electrode firing tip, it ensures quicker firing, smoother starts, better acceleration, and improved fuel efficiency. Its high alumina ceramic insulator enhances thermal conductivity and insulation, providing increased strength and reliability. The multi-rib insulator design prevents flash-over, while the nickel-plated shell resists corrosion for extended service life. With a mid-projection standard center electrode and a tapered seat type, this performance-grade spark plug delivers consistent results. The platinum tip prevents gap erosion, ensuring a longer lifespan, while the nickel ground electrode adds to its durability. Designed to meet the demands of performance enthusiasts, this spark plug is a reliable choice for maintaining engine efficiency and longevity.
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ACDelco – ACDelco Double Platinum Spark Plug, 41-803 (Part No.41-803)

ACDelco Double Platinum Spark Plug, 41-803

from

$11.49
ACDelco Gold (Professional) Double Platinum Spark Plug are a high quality alternative to Original Equipment (OE) parts. With a copper core and double platinum pads on the center electrode, these plugs are designed to deliver long-lasting performance. These premium aftermarket replacement spark plugs are manufactured to meet your expectations for fit, form, and function. ACDelco Gold (Professional) parts are manufactured to meet your expectations for fit, form, and function, making them a smart choice for General Motors vehicles, as well as most makes and models, including special applications. These high-quality parts are backed by General Motors. Some ACDelco Gold parts may have formerly appeared as ACDelco Professional.
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Champion – Champion Copper Plus Spark Plug RV15YC4 – Dependable Performance & Durability, 18 (Part No.18)

Champion Copper Plus Spark Plug RV15YC4 - Dependable Performance & Durability, 18

from

$3.99
Champion Copper Plus spark plugs deliver dependable ignition performance with proven copper-core technology. The copper core electrode provides excellent conductivity and optimized heat control for consistent sparks while the coated shell protects against corrosion. Champion your engine with spark plugs engineered to improve efficiency and keep your vehicle running at its best.
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Motorcraft – Motorcraft Spark Plug: Reliable Ignition & Nickel Durability, SP-425-X (Part No.SP-425-X)

Motorcraft Spark Plug: Reliable Ignition & Nickel Durability, SP-425-X

from

$6.49
The spark plug is designed to deliver reliable ignition performance with its standard center electrode design, ensuring consistent and efficient combustion in your engine. Crafted with nickel for both the center and ground electrode tips, this spark plug offers excellent durability and resistance to wear, making it a dependable choice for long-term use. Its tapered seat type ensures a secure fit, enhancing the overall performance and compatibility with a wide range of vehicles. Built to withstand demanding conditions, this spark plug provides exceptional value by optimizing engine efficiency and contributing to smoother operation.
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Autolite Iridium – Autolite Iridium Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition, XP25 (Part No.XP25)

Autolite Iridium Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition, XP25

from

$11.49
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.
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ACDelco – ACDelco Copper Core Spark Plug: Reliable Performance & Durability, R43TS (Part No.R43TS)

ACDelco Copper Core Spark Plug: Reliable Performance & Durability, R43TS

from

$6.49
ACDelco Professional Conventional Spark Plugs are designed for reliability and efficient performance, and are a high quality replacement for many vehicles on the road today. Their high-quality copper cores and outstanding suppression characteristics deliver reliable performance. They are also available for Marine applications. These premium aftermarket replacement spark plugs are manufactured to meet your expectations for fit, form, and function.
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Autolite Iridium – Autolite Iridium Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition, XP24 (Part No.XP24)

Autolite Iridium Iridium XP Fine wire Spark Plug: Improved Durability, More Focused Ignition, XP24

from

$10.49
Autolite has over 100 years of engineering experience and has sold over 11 billion plugs. Designed and engineered in the USA, the Autolite Iridium XP spark plugs feature an iridium-enhanced 0.6mm finewire design and patented platinum sidewire technology to provide better overall durability and a more focused ignition for enhanced ignitability and performance. Features double Iridium-enhanced alloy technology center electrode for improved durability and wear resistance.
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Champion – Champion Copper Plus Spark Plug RV12YC – Dependable Performance & Durability, 406 (Part No.406)

Champion Copper Plus Spark Plug RV12YC - Dependable Performance & Durability, 406

from

$4.99
Champion Copper Plus spark plugs deliver dependable ignition performance with proven copper-core technology. The copper core electrode provides excellent conductivity and optimized heat control for consistent sparks while the coated shell protects against corrosion. Champion your engine with spark plugs engineered to improve efficiency and keep your vehicle running at its best.
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Motorcraft – Motorcraft Spark Plug, Platinum Center Electrode Tip Material, Copper Core, SP-501 (Part No.SP-501)

Motorcraft Spark Plug, Platinum Center Electrode Tip Material, Copper Core, SP-501

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$7.29
Motorcraft Spark Plug, Platinum Center Electrode Tip Material, Copper Core, SP-501.
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ACDelco – ACDelco Conventional Spark Plug, R85TS (Part No.R85TS)

ACDelco Conventional Spark Plug, R85TS

from

$4.29
ACDelco Gold (Professional) Conventional Spark Plugs are a high quality alternative to Original Equipment (OE) parts. These Conventional Spark Plugs are designed for reliability and efficient performance, and are the high quality replacements for many vehicles on the road today. Their high-quality copper cores and outstanding suppression characteristics deliver reliable performance. They are also available for Marine applications. These premium aftermarket replacement spark plugs are manufactured to meet your expectations for fit, form, and function. ACDelco Gold (Professional) parts are manufactured to meet your expectations for fit, form, and function, making them a smart choice for General Motors vehicles, as well as most makes and models, including special applications. These high-quality parts are backed by General Motors. Some ACDelco Gold parts may have formerly appeared as ACDelco Professional.
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Motorcraft – Motorcraft Spark Plug: Enhanced Durability & Optimized Performance, SP-414-AX (Part No.SP-414-AX)

Motorcraft Spark Plug: Enhanced Durability & Optimized Performance, SP-414-AX

from

$6.99
Enhanced durability and optimized performance define Motorcraft Spark Plugs, the original equipment for Ford, Lincoln, and Mercury vehicles. Engineered to meet strict Ford standards, these spark plugs ensure exact fitment and deliver reliable performance across a wide range of domestic and import cars and trucks. Designed with high-quality materials, they resist oxidation and arc erosion while featuring a multi-rib insulator to protect against misfires. With service intervals of up to 100,000 miles, Motorcraft Spark Plugs help reduce fuel consumption, optimize emissions, and eliminate misfires, making them a cost-effective choice for long-term use. Backed by Motorcraft’s Service Parts Warranty, these ignition components also prevent false check engine lights, offering confidence and peace of mind. Whether you’re maintaining your vehicle’s original performance or upgrading for reliability, Motorcraft Spark Plugs are the trusted solution that was in your vehicle when it was manufactured.
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Spark Plugs Brands You Can Trust For Your Ford F-350 Pickup

9 trusted brands of Spark Plugs line our shelves, ready to help keep your Ford F-350 Pickup running smooth. Below are some of the most popular brands and their top Spark Plugs offerings:

Most Purchased Ford F-350 Pickup Spark Plugs from ACDelco

When you buy the most frequently purchased ACDelco brand Spark Plugs, you can be confident it will be the right part for your Ford F-350 Pickup. Here are the ACDelco Spark Plugs Advanced Auto customers buy the most:
ACDelco Conventional Spark Plug, CR43TS
from $6.49
(177)
ACDelco Conventional Spark Plug, CR43TS
Spark Plugs
ACDelco Conventional Spark Plug, R45TS
from $5.49
(100)
ACDelco Conventional Spark Plug, R45TS
Spark Plugs

FAQs for Ford F-350 Pickup Spark Plugs

What are the most purchased Spark Plugs for the Ford F-350 Pickup?

Out of 96 Spark Plugs for the Ford F-350 Pickup, the most popular in our inventory are:

What are the top-rated Ford F-350 Pickup Spark Plugs?

Top-rated Spark Plugs for your Ford F-350 Pickup based on customer reviews/ratings are:
E3 DiamondFIRE Automotive Spark Plug: More Power & Fuel Efficiency, E3.42
from $8.49
(184)
E3 DiamondFIRE Automotive Spark Plug: More Power & Fuel Efficiency, E3.42
“Replaced my fouled plugs in my 305 sbc with these. The truck is definitely running better than it ever has. Great throttle response.”