Ford E-350 Econoline Manual Transmission Fluids

Your Ford E-350 Econoline will be happy to know that the search for the right Manual Transmission Fluids you’ve been looking for is over! Advance Auto Parts has 11 different Manual Transmission Fluids for your vehicle, ready for shipping or in-store pick up. The best part is, our Ford E-350 Econoline Manual Transmission Fluids start from as little as $9.99.

When it comes to your Ford E-350 Econoline, you want parts and products from only trusted brands. Here at Advance Auto Parts, we work with only top reliable Manual Transmission Fluids brands so you can shop with complete confidence. Some of our top Manual Transmission Fluids brands are Valvoline and Royal Purple. We’re sure you will get the right product to keep that E-350 Econoline running for a long time.

We even have reviews of our OEM and aftermarket Manual Transmission Fluids products to help you buy with confidence. Hear from other customers via the 407,068 reviews on parts for your Ford E-350 Econoline.

Shop online, find the best price on the right product, and have it shipped right to your door. If you prefer to shop in person for the right Manual Transmission Fluids for your E-350 Econoline, visit one of our local Advance Auto Parts locations and you’ll be back on the road in no time!

Compare 15 Ford Manual Transmission Fluids

Valvoline – MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle (ATF) Full Synthetic Automatic Transmission Fluid, 1 Gallon

from

$36.49
Valvoline MaxLife Multi-Vehicle Automatic Transmission Fluid (ATF) is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
  • Long life friction modifiers help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
  • Suitable for 95% of traditional ATFs including Dex/Merc, Mercon LV & Mercon V
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Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart (Part No.881163)

High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 5 Quart

from

$29.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
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Royal Purple – SAE Multi-Grade Synthetic Motor Oil 5W20 (5 Quart) (Part No.51520)

SAE Multi-Grade Synthetic Motor Oil 5W20 (5 Quart)

from

$45.99
Royal Purple Motor Oil is a specially formulated multi viscocity oil for use in gasoline and diesel engines of all types from cars and trucks to SUVs, motorcycles and boats. Royal Purple(R) Motor Oil with Synerlec(R) additive technology reduces friction, which results in a 1-3 percent increase in horsepower, lowers operating temperatures, provides superior corrosion protection, improves fuel economy, reduces emissions and extends oil life. A.P.I. Certified.

Product Features:
  • Better wear protection
  • Increased fuel efficiency
  • Better protection of the expensive catalytic emission system
  • Improved compatibility with fuels containing ethanol
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Valvoline – High Mileage 5W-20 Synthetic Blend Motor Oil, 5 Quart (Part No.881162)

High Mileage 5W-20 Synthetic Blend Motor Oil, 5 Quart

from

$29.99
Even if you dont notice, after 75,000 miles, friction and high temperatures cause leaks, deposits and sludge that shorten the life of your motor. Thats why you need the superior protection of MaxLife, the world’s first high mileage oil, specially formulated to extend the life of your engine. Through its advanced synthetic blend formulation, it supplies boosted wear protection, special seal conditioners, added detergents and anti-oxidant additives that help to maximize the life of an engine. Its advanced formula can also be utilized in newer cars to help prevent the causes of engine breakdown before they ever begin. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition.

Product Features:
  • Seal conditioners rejuvenate aging engine seals to help stop and prevent oil leaks
  • Extra wear protection helps prevent future engine wear
  • Extra detergents help keep older engines cleaner by bonding with and removing sludge and deposits
  • Anti-oxidants help prevent oil breakdown preventing engine-clogging sludge and deposit formation
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Royal Purple – High Performance SAE 5W20 Synthetic Engine Oil, API Certified, 1 QT (Part No.01520)

High Performance SAE 5W20 Synthetic Engine Oil, API Certified, 1 QT

from

$12.99
High Performance Motor Oil API LICENSED MOTOR OIL Royal Purple High Performance Motor Oil combines premium base oils with proprietary additive technologies to create a high performance synthetic engine oil that optimizes performance and protection. Royal Purple High Performance Motor Oils carry the current API and ILSAC engine oil licenses, as well as the GM dexos1 gasoline engine oil approval. ILSAC GF-6 AND GM DEXOS1 Modern gasoline direct injection (GDI) engines have achieved levels of power and fuel economy never before possible in passenger car engines. As a result, smaller engines operate at much higher loads across all engine speeds. This has caused increased wear in critical areas of the engine, and created a destructive phenomenon called low-speed pre-ignition (LSPI). The unique, state-of-the-art additive technology in Royal Purple High Performance engine oils is designed specifically to address these issues, and help engines maintain performance and reliability.

Product Features:
  • Better wear protection
  • Increased protection against low speed pre-ignition
  • Increased fuel efficiency
  • Better protection for vehicle exhaust emissions equipment
  • Improved compatibility with fuels containing ethanol
  • Superior corrosion protection
  • Made in usa
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Valvoline – Advanced Full Synthetic 5W-20 Engine Oil: Maximizes Engine Life, 5 Quart (Part No.881147)

Advanced Full Synthetic 5W-20 Engine Oil: Maximizes Engine Life, 5 Quart

from

$36.99
Today’s advanced engine technology requires advanced protection. Valvoline Advanced Full Synthetic, the motor oil designed to protect today’s sophisticated engines, contains premium anti-wear additives, superior antioxidants and extra detergents. It protects 40% better against wear, resists oil breakdown 10-times better, and defends 25% more against deposits than industry standards for maximum performance and engine longevity. And with an exceptional range of temperature protection your engine will ready for extreme weather. Valvoline invented motor oil 150 years ago, and we’ve been reinventing it ever since. Get Valvoline Advanced Full Synthetic and give your engine the advanced protection proven to maximize engine life.

Product Features:
  • Advanced protection against the four main causes of engine breakdown: wear friction heat and deposits
  • 40% better wear protection vs. industry standard as tested in the sequence ivb engine test
  • 25% better deposit protection with superior engine cleaning detergents as tested in the gmod engine test
  • Exceptional high/low temperature protection defends your motor no matter the weather conditions
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • Advanced engine protection: Valvoline Advanced Full Synthetic Engine Oil is designed to provide advanced protection to today’s sophisticated engines, ensuring maximum performance and engine longevity.
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Valvoline – Full Synthetic High Mileage with MaxLife Technology 10W-30 Engine Oil: Maximizes Engine Life, 5 Quart (Part No.881170)

Full Synthetic High Mileage with MaxLife Technology 10W-30 Engine Oil: Maximizes Engine Life, 5 Quart

from

$37.99
Upgrading your motor oil to Valvoline Full Synthetic High Mileage with MaxLife Technology can help you increase the longevity of your car, truck or SUV with over 75,000 miles. It’s proven to protect your high-mileage motor against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repairs. Our exclusive formulation goes beyond industry standards to protect your engine. It’s fortified with enhanced wear additives and friction-fighting agents to safeguard critical engine components, extra detergents to clean inside your engine, and premium seal conditioners to restore aging seals and prevent leaks. Superior viscosity modifiers and high-quality base oils help it perform exceptionally in both high and low temperatures. Engineered with ingenuity, tested with tenacity, and proven with purpose, our formula was innovated in America with a century and a half of hands-on experience from the original motor oil brand.

Product Features:
  • Enhanced maxlife technology prevents engine breakdown in extreme conditions with 50% better wear protection than the industry standard
  • Treat and prevent leaks with premium seal conditioners to keep oil out of places it shouldn’t be
  • 25% extra defense against deposits, sludge, corrosion and rust via interior-cleansing detergents
  • Extreme temperature protection through our high-quality base oils and superior viscosity modifiers
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • High Mileage Protection: Valvoline Full Synthetic High Mileage Engine Oil is specially designed to protect engines with over 75,000 miles against wear, friction, heat, and deposits, ensuring a longer lifespan for your vehicle.
See More

Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 1 Quart (Part No.VV1556/VV155)

High Mileage with MaxLife Technology Synthetic Blend 5W-30 Motor Oil: Maximize Engine Life, 1 Quart

from

$9.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
See More

Valvoline – DEX/MERC Automatic Transmission Fluid, 1 Gallon (Part No.773636)

DEX/MERC Automatic Transmission Fluid, 1 Gallon

from

$35.99
Valvoline DEX/MERC ATF is a high-quality transmission fluid formulated to meet the challenging demands many automatic transmissions. Its responsive low-temperature fluidity is beneficial in both electronic and hydraulic controlled transmissions and transaxles. Recommended for use in the following applications: MERCON®, DEXRON®-III, Ford M2C138-CJ and M2C166-H, Allison C-4 and TES-389, and Caterpillar TO-2.

Product Features:
  • Formulated with premium base stocks and advanced additive technology to meet the challenging demands of automatic transmissions.
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
See More

Valvoline – Advanced Full Synthetic 5W-30 Engine Oil: Maximizes Engine Life, 1 Quart (Part No.VV955)

Advanced Full Synthetic 5W-30 Engine Oil: Maximizes Engine Life, 1 Quart

from

$11.49
Today’s advanced engine technology requires advanced protection. Valvoline Advanced Full Synthetic, the motor oil designed to protect today’s sophisticated engines, contains premium anti-wear additives, superior antioxidants and extra detergents. It protects 40% better against wear, resists oil breakdown 10-times better, and defends 25% more against deposits than industry standards for maximum performance and engine longevity. And with an exceptional range of temperature protection your engine will ready for extreme weather. Valvoline invented motor oil 150 years ago, and we’ve been reinventing it ever since. Get Valvoline Advanced Full Synthetic and give your engine the advanced protection proven to maximize engine life.

Product Features:
  • Advanced protection against the four main causes of engine breakdown: wear friction heat and deposits
  • 40% better wear protection vs. industry standard as tested in the sequence ivb engine test
  • 25% better deposit protection with superior engine cleaning detergents as tested in the gmod engine test
  • Exceptional high/low temperature protection defends your motor no matter the weather conditions
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn, gm dexos 1 gen 3
  • Superior engine protection: Valvoline SynPower Full Synthetic Engine Oil provides superior protection against engine sludge and varnish, ensuring your engine stays clean and running smoothly.
See More

Valvoline – High Mileage with MaxLife Technology Synthetic Blend 5W-20 Engine Oil: Maximize Engine Life, 1 Quart (Part No.609506)

High Mileage with MaxLife Technology Synthetic Blend 5W-20 Engine Oil: Maximize Engine Life, 1 Quart

from

$9.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • Maxlife technology prevents engine breakdown with 40% better wear protection than the industry standard
  • Refresh aging seals and prevent leaks with seal conditioners
  • Reduce sludge, deposits, corrosion, and rust with added detergents – keep motors clean inside
  • Enhanced friction performance helps maximize power with advanced friction-fighting agents
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • Synthetic Blend: Our unique combination of synthetic and premium conventional oils provides superior protection against wear, friction, heat, and deposits.
See More

Valvoline – High Mileage with MaxLife Technology Synthetic Blend 10W-40 Engine Oil: Maximize Engine Life, 1 Quart (Part No.797977)

High Mileage with MaxLife Technology Synthetic Blend 10W-40 Engine Oil: Maximize Engine Life, 1 Quart

from

$9.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • Maxlife technology prevents engine breakdown with 40% better wear protection than the industry standard
  • Refresh aging seals and prevent leaks with seal conditioners
  • Reduce sludge, deposits, corrosion, and rust with added detergents – keep motors clean inside
  • Enhanced friction performance helps maximize power with advanced friction-fighting agents
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • MaxLife High Mileage Synthetic Blend Engine Oil is specially designed for engines with over 75,000 miles, providing greater protection and maximizing engine life.
See More

Valvoline – Full Synthetic High Mileage with MaxLife Technology 5W-30 Engine Oil: Maximizes Engine Life, 5 Quart (Part No.813531)

Full Synthetic High Mileage with MaxLife Technology 5W-30 Engine Oil: Maximizes Engine Life, 5 Quart

from

$37.99
Upgrading your motor oil to Valvoline Full Synthetic High Mileage with MaxLife Technology can help you increase the longevity of your car, truck or SUV with over 75,000 miles. It’s proven to protect your high-mileage motor against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repairs. Our exclusive formulation goes beyond industry standards to protect your engine. It’s fortified with enhanced wear additives and friction-fighting agents to safeguard critical engine components, extra detergents to clean inside your engine, and premium seal conditioners to restore aging seals and prevent leaks. Superior viscosity modifiers and high-quality base oils help it perform exceptionally in both high and low temperatures. Engineered with ingenuity, tested with tenacity, and proven with purpose, our formula was innovated in America with a century and a half of hands-on experience from the original motor oil brand.

Product Features:
  • Enhanced maxlife technology prevents engine breakdown in extreme conditions with 50% better wear protection than the industry standard
  • Treat and prevent leaks with premium seal conditioners to keep oil out of places it shouldn’t be
  • 25% extra defense against deposits, sludge, corrosion and rust via interior-cleansing detergents
  • Extreme temperature protection through our high-quality base oils and superior viscosity modifiers
  • Meets or exceeds all requirements of ilsac gf-6a, api sp, api sn with sn plus, api sn
  • High Mileage Oil Class: Valvoline MaxLife Synthetic Engine Oil is specially designed for engines with over 75,000 miles, providing superior protection against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repair
See More

Pentosin – PENTOSIN ATF 6 1L (Part No.1058106)

PENTOSIN ATF 6 1L

from

$41.49
PENTOSIN ATF 6 1L

Pentosin – PENTOSIN ATF 6 5L (Part No.1058207)

PENTOSIN ATF 6 5L

from

$131.99
PENTOSIN ATF 6 5L

FAQs for Ford E-350 Econoline Manual Transmission Fluids

What are the most popular Manual Transmission Fluids for the Ford E-350 Econoline?

With 2 brands you can trust, our most popular Manual Transmission Fluids for the Ford E-350 Econoline are:
SAE Multi-Grade Synthetic Motor Oil 5W20 (5 Quart)
from $45.99
(51)
SAE Multi-Grade Synthetic Motor Oil 5W20 (5 Quart)
Manual Transmission Fluids

What are the best aftermarket Manual Transmission Fluids for the Ford E-350 Econoline?

See what past customers had to say about our highest-rated Manual Transmission Fluids for the Ford E-350 Econoline:
High Mileage 5W-20 Synthetic Blend Motor Oil, 5 Quart
from $29.99
(371)
High Mileage 5W-20 Synthetic Blend Motor Oil, 5 Quart
“This is a great product to use”