2026 Lexus RX350 Fluids and Chemicals

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Essential Fluids and Chemicals for 2026 Lexus RX350s

Pennzoil – Ultra Platinum 5W-30 Full Synthetic Motor Oil, Unbeatable Engine Protection, 946 mL (Part No.550040843)

Ultra Platinum 5W-30 Full Synthetic Motor Oil, Unbeatable Engine Protection, 946 mL

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$169.99
Pennzoil Ultra Platinum Full Synthetic 5W-30 motor oil is our most advanced formulation with unbeatable wear and sludge protection, as well as unbeatable cleanliness. When it comes to torturous driving conditions, trust the unbeatable engine protection(1) of Pennzoil Ultra Platinum. It far exceeds the most stringent car manufacturer requirements for cleanliness and protection (based on ILSAC GF-6); it offers outstanding performance in extreme temperatures and better fuel economy (based on the latest industry standard) Pennzoil Ultra Platinum helps extend the life of your engine and protects for up to 20 years or 750,000 miles, whichever comes first(1)(1), to give you peace of mind to drive every mile as hard as you can, from your daily commute to sand dunes and mountain terrain ((1)Based on Sequence IVA wear test; Sequence IIIH oxidation and deposit test; and the Sequence VH sludge test.if you exclusively use Pennzoil Ultra Platinum Full Synthetic motor oil. Your engine must have fewer than 125,000 miles and have been manufactured in the past 72 months.. .)

Product Features:
  • Our most advanced full synthetic 5W-30 engine oil, designed for unbeatable engine protection(1)
  • Made with natural gas
  • Outstanding performance in extreme temperatures
  • Designed for high-performance engines, it helps protect engines from loss of power
  • Provides unsurpassed wear protection for your engine (based on Sequence IVA wear test using SAE 5W-30)
  • Provides better fuel economy (based on the latest industry standard)
  • Exceeds the requirements of the following industry specifications: API SP-Resource Conserving and all previous categories; ILSAC GF-6A; ACEA A1/B1 and ACEA A5/B5
  • Meets or exceeds the following OEM requirements: Chrysler MS-6395; WSS-M2C961-A1; Honda/Acura HT0-06
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Mobil 1 – High Mileage 5W-30 Full Synthetic Motor Oil, Extends Engine Life, 1 Quart (Part No.14999)

High Mileage 5W-30 Full Synthetic Motor Oil, Extends Engine Life, 1 Quart

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$12.99
Give your higher mileage engine the care it deserves with Mobil 1 High Mileage full-synthetic motor oil 0W-20. This formula utilizes Mobil 1’s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles with over 75,000 miles. Mobil 1 High Mileage motor oil extends engine life by reducing friction and preventing deposits and sludge buildup – keeping critical engine parts clean and protected for up to 10,000 miles between oil changes.(1) Mobil 1 helps to keep your engine running at lower temperatures(2) and is proven to cool engine temperatures by over 10%.(3) Mobil 1 High Mileage full-synthetic motor oil 5W-30 also helps control oxidation to prevent oil breakdown and is recommended by ExxonMobil for all types of modern cars, SUVs, light vans, and light trucks – including those with high-performance, turbocharged, supercharged, multi-valve, or fuel-injected engines. Mobil 1 is America’s No. 1 selling synthetic motor oil brand at retail, (4) trusted and recommended by car builders and experienced mechanics, and is the Official Motor Oil of NASCAR®. ((1)Protects for up to 10,000 miles or 1 year, whichever comes first. To learn more about the Mobil 1 Limited Warranty, visit Mobil.US. (2)Compared to conventional oil. (3) Based on proprietary engine testing results may vary. (4) Source: The NPD Group/ Retail Tracking Service/ Dollar Sales/ PCMO full-synthetic/ 52 weeks ending September 30, 2023)

Product Features:
  • Mobil 1 High Mileage full-synthetic motor oil 5W-30 is designed for engines with over 75,000 miles to go up to 10,000 miles between oil changes (1)
  • Utilizes Mobil 1’s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness
  • Meets ILSAC GF-6 standards to help provide low-speed pre-ignition (LSPI) and timing chain wear protection while keeping your engine clean and helping to improve your fuel economy
  • Provides excellent internal engine heat protection (up to 500 degrees F) and low temperature protection (to -30 degrees F)
  • Helps extend engine life by working to prevent damaging deposits and sludge buildup
  • Manufacturer part number: 103767
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Castrol – Edge 5W-30 Full Synthetic Motor Oil, Superior Wear Protection, 5 Quart (Part No.1598B1)

Edge 5W-30 Full Synthetic Motor Oil, Superior Wear Protection, 5 Quart

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$41.99
Castrol EDGE 5W-30 Full Synthetic Motor Oil is engineered for drivers seeking peak engine performance and unmatched protection. With a formula that is 3X stronger against viscosity breakdown and delivers 10X better high-stress performance, this oil ensures your engine operates smoothly under demanding conditions. Designed for extended use, it offers up to 20,000 miles or one year between oil changes, making it a cost-effective choice for long-term reliability. Its advanced composition exceeds API SQ/SP/SN PLUS/SN standards and meets stringent requirements from Chrysler and Ford, ensuring compatibility with a wide range of vehicles. The 5W-30 weight provides optimal viscosity control and thermal stability, enhancing fuel economy and safeguarding against sludge buildup. Whether you’re navigating high temperatures or heavy loads, this full synthetic oil delivers superior wear protection and performance in critical areas, making it the ultimate solution for maintaining your engine’s health and efficiency.

Product Features:


    Product Features:
    • 3X Stronger than the leading full synthetic (1)
    • 10X Better high stress performance (2)
    • 20,000 miles between oil changes (3)
    • (1) Viscosity breakdown as measured in Kurt Orbahn test on 5W-30 grade
    • (2) As measured in Seq IX test under high load/torque conditions vs. API SQ test limits
    • (3) Or one year, whichever comes first
    • Approved and Licensed Specifications:
    • Exceeds API SQ/SP/SN PLUS/SN
    • ILSAC GF-7
    • Meets engine test requirements of Chrysler MS 6395
    • Meets Ford WSS-M2C945-B1
    • Meets Ford WSS-M2C960-A1
    • Meets Ford WSS-M2C961-A1
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Valvoline – High Mileage 5W-30 Synthetic Blend Motor Oil, Prevents Engine Breakdown, 5 Quart (Part No.881163)

High Mileage 5W-30 Synthetic Blend Motor Oil, Prevents Engine Breakdown, 5 Quart

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$33.99
75,000 miles is more than a mile marker. It’s a signal that your engine is ready for greater protection. That’s when you need Valvoline High Mileage with MaxLife Technology Motor Oil. Its exclusive formula is proven to maximize engine life in cars, trucks, and SUVs with over 75,000 miles. Our mixture is specially developed with a unique combination of synthetic and premium conventional oils to protect your high-mileage motor against wear, friction, heat, and deposits – the four major causes of engine breakdown and expensive repairs. Anti-wear additives defend critical engine components, advanced friction-fighting agents reduce heat and abrasion, added detergents clean the inside of your engine, and premium seal conditioners handle aging seals to prevent leaks. It fights sludge, corrosion and rust that can rob your engine of horsepower, fuel efficiency and longevity. From extreme temperatures and cold starts to stop-and-go traffic and frequent short trips, viscosity modifiers make sure the oil flows more easily, coats more completely, and resists thermal breakdown under even the most intense driving conditions. Its unique mixture curbs contaminants to keep high-mileage engines from burning and consuming oil that can foul spark plugs, creating higher emissions and causing your motor to run roughly.

Product Features:
  • MAXLIFE TECHNOLOGY PREVENTS engine breakdown with 40% better wear protection than the industry standard
  • REFRESH AGING SEALS AND PREVENT LEAKS with seal conditioners
  • REDUCE SLUDGE, DEPOSITS, CORROSION, AND RUST with added detergents – keep motors clean inside
  • ENHANCED FRICTION PERFORMANCE HELPS MAXIMIZE POWER with advanced friction-fighting agents
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
  • MaxLife Technology: Valvoline High Mileage with MaxLife Technology is specially formulated to maximize engine life in vehicles with over 75,000 miles, providing superior protection against wear, friction, heat, and deposits.
  • Synthetic Blend Composition: This motor oil features a unique combination of synthetic and premium conventional oils, ensuring optimal performance and protection for high-mileage engines.
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ARGOS – Universal Yellow 50/50 Pre-Diluted Antifreeze, 1 Gallon (Part No.AR401)

Universal Yellow 50/50 Pre-Diluted Antifreeze, 1 Gallon

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$11.99
ARGOS Extended Life AMAM 50/50 is compatible with ANY antifreeze/coolant in ANY vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with Prime Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. ARGOS 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT & IAT
  • 5 Yr., 150,000 mile Extended life formula.
  • Meets or exceeds ASTM D3306 & D4985 for corrosion protection.
  • Ready to Use formula (prediluted to a 50% Eg & 50% distilled water mix). Perfect for small volume top-off or complete drain and refill of the cooling system
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FRAM – All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon (Part No.F401)

All Vehicles Antifreeze, 50/50 Ready-to Use, 1 Gallon

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$10.99
FRAM Extended Life AMAM 50/50 is compatible with any antifreeze/coolant in any vehicle with aluminum or other cooling system metals. The formulas have a blend of long-lasting inhibitors to guard against temperature extremes and the effects of rust, corrosion, and premature water pump failure. Top-off your cooling system with FRAM Extended Life AMAM 50/50, which is a blend of 50% antifreeze and 50% demineralized water. FRAM 50/50 meets or exceeds ASTM D3306 and D4985 for corrosion protection for cars and light duty trucks, while providing reliable freeze-up and boil-over protection.

Product Features:
  • Formulated to work with All Vehicles. Universally works with all fluid colors; All OAT, POAT, HOAT and IAT
  • 5 year/150,000 mile Extended life formula.
  • Meets or exceeds ASTM D3306 and D4985 for corrosion protection.
  • Ready to Use formula (prediluted to a 50% Eg and 50% distilled water mix). Perfect for small volume top-off or complete drain and refill of the cooling system
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Prestone – MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon (Part No.AF2800)

MAX Antifreeze + Coolant: All Vehicles, Concentrate, 1 Gallon

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$21.99
All Antifreeze + Coolants are not the same. Prestone MAX antifreeze + coolant is GUARANTEED to provide MAXIMUM ENGINE PROTECTION in all Vehicle Makes, Models & Years. It delivers the widest range of temperature protection, industry leading protection from engine damaging rust & corrosion and the longest lasting protection in the industry. Trust Prestone for maximum, year-round engine protection.

Product Features:
  • Can top off or replace all antifreeze + coolant colors and formulations in all Vehicle Makes, Models & Years – Guaranteed.
  • Our patented, advance formula provides extreme temperature protection from the worst of winter deep freezes and scorching summer heat.
  • We deliver industry leading protection from engine damaging rust, corrosion & buildup. Prestone MAX completely stops the formation of rust & corrosion for better engine performance and longer engine life.
  • Prestone Max is guaranteed to protect your vehicle for 15+ years and/or 350,000 miles. It’s the longest fluid life in the industry.
  • This is a Concentrated Formula. Must mix with high quality water to the desired ratio.
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Valvoline – Restore & Protect Automatic Transmission Fluid 1 Ga (Part No.913033)

Restore & Protect Automatic Transmission Fluid 1 Ga

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$37.99
Most transmissions are automatic. Now, so is choosing an ATF. Introducing Valvoline Restore & Protect Automatic Transmission Fluid, a premium full synthetic ATF suitable for use in 95% of vehicles. Leveraging innovation from our groundbreaking Valvoline Restore & Protect Motor Oil, the same trusted technology is now available in transmission care. Restore & Protect ATF provides up to 97% deposit removal with Active Dissolve Technology, so there’s no need to add a transmission cleaner. Valvoline’s full synthetic formula outperforms conventional ATF with outstanding protection against friction, thermal stability and transmission breakdown. The high performance multi-vehicle protection revitalizes, defends and maximizes automatic transmission life. Whether it’s a Ford, GM, Toyota, Honda, Hyundai, Subaru, BMW, Mercedes, VW and more, you get exceptional performance in any driving condition. For unsurpassed deposit removal and smoother shifting, trust Valvoline Restore & Protect Full Synthetic Automatic Transmission Fluid, from the number 1 ATF brand.

Product Features:
  • Removes up to 97% of damaging deposits with Active Dissolve Technology, so you can skip the transmission cleaner
  • The number 1 ATF brand brings the same innovation from Valvoline Restore & Protect Motor Oil to its groundbreaking automatic transmission fluid technology
  • Valvoline Restore & Protect Automatic Transmission Fluid is suitable for use in more than 95% of ATF vehicles in operation with US registered light duty applications
  • Premium full synthetic formula with advanced additive chemistry fights harmful friction and thermal breakdown to help prevent costly transmission repairs
  • Proven to maximize transmission life, the high performance protection revitalizes, defends, minimizes deposits and ensures smooth shifting
  • Recommended For Use In Applications Requiring Dexron 6, Dexron 3, Dexron 2, Mercon Lv, And Jaso M315-2013 1A-Lv
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Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

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$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
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Valvoline – MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

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$39.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base oils and long life friction modifiers to help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Valvoline – Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon (Part No.882505)

Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon

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$59.99
Valvoline SAE 75W-90 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our detergent package-based formulation contains Full Synthetic base stocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance. Protect your gears with Valvoline, the No. 1 gear oil brand.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION , ranging from -30 Deg F to 300 Deg F
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTIONá, ranging from -30 Deg F to 300 Deg F
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALS where APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALSáwhere APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS THE PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Royal Purple – Max Performance Synthetic Power Steering Fluid (Part No.01326)

Max Performance Synthetic Power Steering Fluid

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$6.99
Max Performance Synthetic Power Steering Fluid

Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

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$18.99
We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:
  • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Prestone – Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 Oz. (Part No.AS261Y/1)

Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 32 Oz.

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$10.49
Prestone Power Steering Fluid (PSF) delivers increased system life. Designed with Anti-wear System Protection, Prestone PSF protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 50,000 Mile Fluid Life
  • Anti-Wear Protection = Increased System Life. Protects against pump failure, squeals and clogs. Corrosion protection for metals, rubber & gasket components.
  • For use in all manufacturers
  • Conventional Formula – For use in all manufacturers
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Prestone – Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 12 Oz. (Part No.AS260)

Power Steering Fluid: All Vehicles, Anti-Wear Protection, 50k miles, 12 Oz.

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$5.49
Prestone Power Steering Fluid (PSF) delivers increased system life. Designed with Anti-wear System Protection, Prestone PSF protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 50,000 Mile Fluid Life
  • Anti-Wear Protection = Increased System Life. Protects against pump failure, squeals and clogs. Corrosion protection for metals, rubber & gasket components.
  • For use in all manufacturers
  • Conventional Formula – For use in all manufacturers
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Mobil 1 – Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart (Part No.25201)

Full Synthetic ATF: Automatic Transmission Fluid, Outperforms Conventional ATFs, 1 Quart

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$11.99
Mobil 1 Synthetic ATF is a multi-vehicle, fully synthetic automatic transmission fluid that helps to improve overall transmission durability and cleanliness. Has exceptional thermal and oxidation stability and long-term frictional properties that help to improve and extend transmission efficiency, smooth shifting performance, and fuel economy. Mobil 1 ATF provides excellent low-temperature fluidity to promote reliable lubrication at temperatures down to -51C, and exceptional shear stability to help supports viscosity retention under the most severe heavy-duty, high-temperature operating conditions. Compatible with mineral ATF fluids and all common seal materials to help provide excellent leakage control and reduce concern in top-off emergencies. Meets or exceeds the requirements of JASO 1-A and Ford MERCON V. For more information, visit us at Mobil.US.

Product Features:
  • Mobil 1 Synthetic ATF is a multi-vehicle automatic transmission fluid that helps to improve overall transmission durability and cleanliness
  • Exceptional thermal and oxidation stability to improve and extend transmission efficiency, smooth shifting performance, and fuel economy
  • Excellent high and low-temperature fluidity to help support viscosity retention under extreme, heavy-duty operating conditions
  • Compatible with mineral ATF fluids and all common seal materials to help provide excellent leakage control
  • Meets or exceeds the requirements of JASO 1-A and Ford MERCON V
  • Manufacturer Part Number: 112980
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Prestone – Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz. (Part No.AS263Y)

Power Steering Fluid: All Vehicles, With Stop Leak, Restores & Conditions Seals, 50k miles, 32 Oz.

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$12.49
Prestone Power Steering Fluid + Stop Leak (PSF+SL) delivers increased system life and prevents & stops system leaks. Stop Leak additives renew, restore and condition seals in the power steering system. These seals harden and shrink over time which are the likely cause of leaks. The stop leak additives also prevent leaks by rejuvenating seals before they leak. Also designed with Anti-wear System Protection, Prestone PSF+SL protects against pump failure, squeals and clogs. This 50,000 mile fluid life is formulated for use in all manufacturers; cars, SUVs, crossovers, and light and medium duty trucks. This a conventional fluid. Many cars 2006 and newer use synthetic based fluids for longer life and better protection. Conventional and synthetic fluids can be mixed but performance and replacement intervals are reduced by the conventional fluid.

Product Features:
  • 50,000 Mile Fluid Life
  • Includes Stop Leak Additives to prevent and stop power steering system leaks.
  • Anti-Wear Protection = Increased System Life. Protects against pump failure, squeals and clogs. Corrosion protection for metals, rubber & gasket components.
  • Conventional Formula – For use in all manufacturers
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Idemitsu – Idemitsu Power Steering Fluid – 12 oz (Part No.30102-052A)

Idemitsu Power Steering Fluid - 12 oz

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$6.99
Idemitsu Power Steering Fluid is formulated with premium quality base oils and the latest additive technologies to provide outstanding protection and performance under the most servere environmental and driving conditions.Idemitsu Premium PSF can be used in most Asian Original Equipment Manufacturer (OEM) power steering units that do not utilize electronic power steering technology.

Product Features:
  • Unique friction technology provides efficient and noise-free operation
  • Advanced formulation technology provides outstanding protection to the entire power steering system while delivering smooth performance under the most severe operating conditions
  • Unique friction technology provides efficient and noise-free operation
  • Excellent compatibility with seals, gaskets and internal components to reduce the potential for leaks and ensures smooth performance over extended intervals
  • Robust anti-wear and inhibitor chemistry provides enhanced component and fluid durability and long-life
  • Advanced formulation technology provides outstanding protection to the entire power steering system while delivering smooth performance under the most severe operating conditions
  • Superior low temperature performance for easy flow and protection against cavitation and elimination of “squawking” and “squealing”
  • Excellent compatibility with seals, gaskets and internal components to reduce the potential for leaks and ensures smooth performance over extended intervals
  • Robust anti-wear and inhibitor chemistry provides enhanced component and fluid durability and long-life
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Valvoline – Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.820681)

Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

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$36.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON®, GM DEXRON®-II and DEXRON®-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III , Toyota/Lexus Type T, T-III and T-IV , Honda/Acura ATF-Z1 (except in CVTs) , Mercedes Benz NAG1 , Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Valvoline – Daily Protection 5W-30 Synthetic Blend Motor Oil, Supports Fuel Efficiency, 1 Quart (Part No.797975/VV177)

Daily Protection 5W-30 Synthetic Blend Motor Oil, Supports Fuel Efficiency, 1 Quart

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$7.99
Valvoline Daily Protection Motor Oil is specially formulated to exceed industry standards for wear, deposit and sludge protection to help keep engines running like new. Developed with high quality additives and premium base oils, it’s designed to flow easily at cold temperatures, reducing wear at startup and providing added protection against motor oil breakdown in tough conditions. For enhanced fuel efficiency, choose Daily Protection Synthetic Blend 5W-20 or 5W-30. Developed with low-friction technology to support strong fuel economy.

Product Features:
  • Extra wear protection designed to help keep automotive engine parts like new
  • Added detergents help protect against sludge and deposits
  • High quality additives resist motor oil breakdown in tough conditions
  • Low-friction formula supports strong fuel efficiency
  • Premium formulation flows easily at low temperatures reducing wear at start-up
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Royal Purple – HMX 5W-20 High Mileage Synthetic Motor Oil, Restores Engine Performance, 5 Quart (Part No.17518)

HMX 5W-20 High Mileage Synthetic Motor Oil, Restores Engine Performance, 5 Quart

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$65.99
Royal Purple HMX SAE 5W-20 High-Mileage Synthetic Motor Oil, 5 quart is specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles. Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology Synerlec, HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines. In addition, HMX is fortified with stout detergents to remove engine build-up and deposits, maintain cleanliness and promote engine longevity.

Product Features:
  • Specifically designed to minimize wear and restore lost performance in engines with more than 75,000 miles
  • Formulated with robust zinc/phosphorus anti-wear compounds combined with Royal Purple’s proprietary additive technology
  • HMX is chemically enhanced to revitalize hardened seals, reducing oil consumption common in high-mileage engines
  • Reduces friction and metal-to-metal contact for peak engine performance
  • Also provides outstanding oxidation resistance to safely extend oil drain intervals, and an ionic attraction to metal surfaces, providing protection and minimizing wear at start-up
  • Superior Engine Cleanliness: Fortified with stout detergents, this oil effectively removes engine build-up and deposits, maintaining cleanliness and promoting engine longevity.
  • High-Mileage Protection: Classified as a high-mileage oil, it provides specialized protection for older engines, ensuring they run smoothly and efficiently.
  • Synthetic Composition: With a synthetic oil composition and an SAE weight of 5W-20, it offers excellent performance and protection in a wide range of temperatures.
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Valvoline – High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon (Part No.881048)

High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon

from

$104.99
If you have over 75,000 miles, you need the superior protection of America’s first high mileage Motor Oil. Valvoline High Mileage MaxLife helps extend the life of your vehicle by fighting the four major signs of engine wear – reduced power, loss of fuel economy, oil leaks and increased oil consumption. The synthetic blend formula contains extra additives designed to combat these problems unique to aging cars and trucks. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition.

Product Features:


    Product Features:
    • Seal conditioners rejuvenate aging engine seals to help stop and prevent oil leaks
    • Extra wear protection helps prevent future engine wear
    • Extra detergents help keep older engines cleaner by bonding with and removing sludge and deposits
    • Anti-oxidants help prevent oil breakdown, preventing engine-clogging sludge and deposit formation
    • Designed to combat low-speed pre-ignition in gasoline direct-injected engines, ensuring optimal performance and protection for modern aging vehicles.
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Valvoline – Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart (Part No.881168)

Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart

from

$38.99
Upgrading your motor oil to Valvoline Full Synthetic High Mileage with MaxLife Technology can help you increase the longevity of your car, truck or SUV with over 75,000 miles. It’s proven to protect your high-mileage motor against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repairs. Our exclusive formulation goes beyond industry standards to protect your engine. It’s fortified with enhanced wear additives and friction-fighting agents to safeguard critical engine components, extra detergents to clean inside your engine, and premium seal conditioners to restore aging seals and prevent leaks. Superior viscosity modifiers and high-quality base oils help it perform exceptionally in both high and low temperatures. Engineered with ingenuity, tested with tenacity, and proven with purpose, our formula was innovated in America with a century and a half of hands-on experience from the original motor oil brand.

Product Features:
  • ENHANCED MAXLIFE TECHNOLOGY PREVENTS engine breakdown in extreme conditions with 50% better wear protection than the industry standard
  • TREAT AND PREVENT LEAKS with premium seal conditioners to keep oil out of places it shouldn’t be
  • 25% EXTRA DEFENSE AGAINST DEPOSITS, sludge, corrosion and rust via interior-cleansing detergents
  • EXTREME TEMPERATURE PROTECTION through our high-quality base oils and superior viscosity modifiers
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
  • Enhanced Wear Protection: Fortified with advanced wear additives to safeguard critical engine components, ensuring longevity for vehicles with over 75,000 miles.
  • Friction-Fighting Agents: Contains friction-fighting agents to reduce engine friction, enhancing overall engine efficiency and performance.
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Valvoline – MaxLife 5W-30 Synthetic Blend Motor Oil, Extends Engine Life, 5 Gallon (Part No.881047)

MaxLife 5W-30 Synthetic Blend Motor Oil, Extends Engine Life, 5 Gallon

from

$104.99
If you have over 75,000 miles, you need the superior protection of America’s first high mileage Motor Oil. Valvoline High Mileage MaxLife helps extend the life of your vehicle by fighting the four major signs of engine wear – reduced power, loss of fuel economy, oil leaks and increased oil consumption. The synthetic blend formula contains extra additives designed to combat these problems unique to aging cars and trucks. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition.

Product Features:


    Product Features:
    • Seal conditioners rejuvenate aging engine seals to help stop and prevent oil leaks
    • Extra wear protection helps prevent future engine wear
    • Extra detergents help keep older engines cleaner by bonding with and removing sludge and deposits
    • Anti-oxidants help prevent oil breakdown, preventing engine-clogging sludge and deposit formation
    • Helps protect gasoline direct injected engines from low-speed pre-ignition, ensuring reliable performance in modern vehicles.
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Mobil 1 – High Mileage 5W-30 Full Synthetic Motor Oil, Protection For 10K Miles, 5 Quart (Part No.120769)

High Mileage 5W-30 Full Synthetic Motor Oil, Protection For 10K Miles, 5 Quart

from

$40.99
Give your higher mileage engine the care it deserves with Mobil 1 High Mileage full-synthetic motor oil 5W-30. This formula utilizes Mobil 1s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness to vehicles with over 75,000 miles. Mobil 1 High Mileage motor oil extends engine life by reducing friction and preventing deposits and sludge buildup-keeping critical engine parts clean and protected for up to 10,000 miles between oil changes.

Product Features:


    Product Features:
    • Mobil 1 High Mileage full-synthetic motor oil 5W-30 is designed for engines with over 75,000 miles to go up to 10,000 miles between oil changes
    • Utilizes Mobil 1s signature Triple Action Formula to deliver outstanding engine performance, protection, and cleanliness
    • Meets ILSAC GF-6 standards to help provide low-speed pre-ignition (LSPI) and timing chain wear protection while keeping your engine clean and helping to improve your fuel economy
    • Provides excellent internal engine heat protection (up to 500 Degrees F) and low temperature protection (to -30 Degrees F)
    • Mobil 1 is specially formulated to help remove sludge and lower engine temperatures
    • Manufacturer Part Number: 120769
    • Extended Engine Life: This high mileage motor oil extends engine life by reducing friction and preventing deposits and sludge buildup, keeping critical engine parts clean and protected for up to 10,000 miles between oil changes.
    • Temperature Control: Proven to cool engine temperatures by over 10%, Mobil 1 helps to keep your engine running at lower temperatures compared to conventional oil.
    • Oxidation Control: Mobil 1 High Mileage motor oil helps control oxidation to prevent oil breakdown, ensuring long-lasting performance and protection.
    • Versatile Compatibility: Recommended by ExxonMobil for all types of modern cars, SUVs, light vans, and light trucks, including those with high-performance, turbocharged, supercharged, multi-valve, or fuel-injected engines.
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Mobil 1 – Mobil 1 Synthetic Gear Lubricant LS 75W-90, 1 Quart (Part No.26101)

Mobil 1 Synthetic Gear Lubricant LS 75W-90, 1 Quart

from

$19.99
Mobil 1 Synthetic Gear Lubricant LS 75W-90 is a supreme, multi-purpose automotive gear lubricant that helps to provide exceptional thermal stability and resistance to high temperature oxidation, extending gear life due to minimal deposits. Helps to deliver outstanding protection against low speed/high torque wear with the capability to handle severe driving conditions while delivering smooth efficient performance. Mobil 1 Synthetic Gear Lubricant LS provides exceptional shear stability, corrosion protection, and enhanced frictional properties. Compared to conventional hypoid gear lubricants, Mobil 1 LS 75W-90 performs exceptionally over a wide range of temperatures to reduce wear at start up. Mobil 1 gear lube helps to minimize leakage and reduce contamination while providing good resistance to foaming to maintain film strength for reliable lubrication. Meets or exceeds the requirements of the following industry specifications: API GL-5.

Product Features:
  • Mobil 1 LS synthetic automotive gear lubricant exceeds the highest level of performance requirements of modern passenger vehicles
  • Helps to provide exceptional thermal stability and resistance to high temperature oxidation and extend gear life due to minimal deposits
  • Delivers outstanding protection against low speed/high torque wear, handling severe driving conditions with smooth, efficient performance
  • Compared to conventional hypoid gear lubricants, performs exceptionally over a wide range of temperatures to reduce wear at start up
  • Provides exceptional shear stability, corrosion protection, and enhanced frictional properties
  • Manufacturer Part Number: 104361
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Valvoline – Extended Protection 5W-30 Full Synthetic Motor Oil, Maximizes Engine Life, 5 Quart (Part No.899391)

Extended Protection 5W-30 Full Synthetic Motor Oil, Maximizes Engine Life, 5 Quart

from

$41.99
Introducing the ultimate protection for vehicles with more than 75,000 miles: Valvoline Extended Protection Full Synthetic High Mileage Motor Oil with Ultra MaxLife Technology. Engineered to maximize engine life, it’s 10x stronger against oil breakdown and provides 50% better wear protection than industry standards. The new formulation combines Valvoline’s premium full synthetic with Ultra MaxLife Technology featuring seal conditioners to rejuvenate aging seals and prevent oil leaks. The result is our best performing motor oil ever for high mileage vehicles. It helps prevent engine breakdown in extreme operating conditions and is proven to protect high-mileage motors against wear, friction, heat, and deposits – the leading causes of expensive repairs. After 75,000 miles, your engine is ready for greater protection. Upgrade to Valvoline Extended Protection Full Synthetic High Mileage with Ultra MaxLife Technology and keep your car on the road for years to come.

Product Features:
  • Our best performing high-mileage engine oil is formulated with ultra maxlife technology, the ultimate protection for vehicles with more than 75,000 miles
  • Valvoline extended protection full synthetic high mileage engine oil is designed with premium seal conditioners to treat and prevent oil leaks
  • 10x stronger against oil breakdown and 50% greater wear protection than industry standards
  • Enhanced wear additives and friction-fighting agents to safeguard critical engine components
  • Maximizes engine life: Valvoline Extended Protection Full Synthetic High Mileage Engine Oil is engineered to maximize engine life, providing superior wear protection and preventing expensive repairs.
  • Ultra MaxLife Technology: The new formulation combines Valvoline’s premium full synthetic with Ultra MaxLife Technology featuring seal conditioners to rejuvenate aging seals and prevent oil leaks.
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Valvoline – Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart (Part No.881159)

Daily Protection 5W-30 Synthetic Blend Motor Oil, Strong Fuel Efficiency, 5 Quart

from

$29.99
Valvoline Daily Protection Motor Oil is specially formulated to exceed industry standards for wear, deposit and sludge protection to help keep engines running like new. Developed with high quality additives and premium base oils, it’s designed to flow easily at cold temperatures, reducing wear at startup and providing added protection against motor oil breakdown in tough conditions. For enhanced fuel efficiency, choose Daily Protection Synthetic Blend 5W-20 or 5W-30. Developed with low-friction technology to support strong fuel economy.

Product Features:
  • Extra wear protection designed to help keep automotive engine parts like new
  • Added detergents help protect against sludge and deposits
  • High quality additives resist motor oil breakdown in tough conditions
  • Low-friction formula supports strong fuel efficiency
  • Premium formulation flows easily at low temperatures reducing wear at start-up
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Upgrade your 2026 Lexus RX350 with Top-Quality Fluids and Chemicals

When it comes to maintaining or upgrading your 2026 Lexus RX350, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Lexus or enhancing its overall performance, Fluids and Chemicals are key to keeping your RX350 functioning at its best. At Advance Auto Parts, we offer a wide selection of 12 Fluids and Chemicals for the 2026 Lexus RX350, designed to meet your needs without breaking the bank. From Transmission Fluid replacements to Coolant/Antifreeze upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Fluids and Chemicals for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Fluids and Chemicals for your 2026 Lexus RX350 at great prices. Our Fluids and Chemicals inventory for this model ranges from just $14.99 to $104.99, with an average price of $35.57. Our 12 Fluids and Chemicals in stock come from 4 trusted brands, so you’re sure to find the right part for your 2026 Lexus RX350 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2026 Lexus RX350, we stock popular OEM and aftermarket Fluids and Chemicals from top names like Valvoline, ZEREX, Pentosin, and more. Valvoline Fluids and Chemicals start at just $18.99 and boast an impressive 4.8 stars average rating from customers. ZEREX and Pentosin also bring quality to the table, with Fluids and Chemicals available starting at $22.99, and at an average 4.8 stars rating. With 1,836 customer reviews and counting, our 2026 Lexus RX350 Fluids and Chemicals have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Fluids and Chemical upgrades. Explore related part types like Drivetrains, Towing Products and more to make sure your 2026 Lexus RX350 is always ready to roll. We’re committed to providing you with everything you need to keep your RX350 in top shape, all in one place. Start shopping confidently below for your 2026 Lexus RX350!

Best-Selling Transmission Fluids for 2026 Lexus RX350s

Enhance the driving experience in your Lexus with 3 quality Transmission Fluid components, starting at $14.99.

Valvoline – Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart (Part No.881168)

Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart

from

$38.99
Upgrading your motor oil to Valvoline Full Synthetic High Mileage with MaxLife Technology can help you increase the longevity of your car, truck or SUV with over 75,000 miles. It’s proven to protect your high-mileage motor against wear, friction, heat, and deposits – the leading causes of engine breakdown and expensive repairs. Our exclusive formulation goes beyond industry standards to protect your engine. It’s fortified with enhanced wear additives and friction-fighting agents to safeguard critical engine components, extra detergents to clean inside your engine, and premium seal conditioners to restore aging seals and prevent leaks. Superior viscosity modifiers and high-quality base oils help it perform exceptionally in both high and low temperatures. Engineered with ingenuity, tested with tenacity, and proven with purpose, our formula was innovated in America with a century and a half of hands-on experience from the original motor oil brand.

Product Features:
  • ENHANCED MAXLIFE TECHNOLOGY PREVENTS engine breakdown in extreme conditions with 50% better wear protection than the industry standard
  • TREAT AND PREVENT LEAKS with premium seal conditioners to keep oil out of places it shouldn’t be
  • 25% EXTRA DEFENSE AGAINST DEPOSITS, sludge, corrosion and rust via interior-cleansing detergents
  • EXTREME TEMPERATURE PROTECTION through our high-quality base oils and superior viscosity modifiers
  • MEETS OR EXCEEDS ALL REQUIREMENTS of ILSAC GF-6A, API SP, API SN with SN PLUS, API SN
  • Enhanced Wear Protection: Fortified with advanced wear additives to safeguard critical engine components, ensuring longevity for vehicles with over 75,000 miles.
  • Friction-Fighting Agents: Contains friction-fighting agents to reduce engine friction, enhancing overall engine efficiency and performance.
See More

Valvoline – High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon (Part No.881048)

High Mileage MaxLife 0W-20 Synthetic Blend Motor Oil, Fights Engine Wear, 5 Gallon

from

$104.99
If you have over 75,000 miles, you need the superior protection of America’s first high mileage Motor Oil. Valvoline High Mileage MaxLife helps extend the life of your vehicle by fighting the four major signs of engine wear – reduced power, loss of fuel economy, oil leaks and increased oil consumption. The synthetic blend formula contains extra additives designed to combat these problems unique to aging cars and trucks. Valvoline High Mileage with Maxlife Technology meets the API SN with SN PLUS specification, protecting gasoline direct injected engines from low-speed pre-ignition.

Product Features:


Product Features:
  • Seal conditioners rejuvenate aging engine seals to help stop and prevent oil leaks
  • Extra wear protection helps prevent future engine wear
  • Extra detergents help keep older engines cleaner by bonding with and removing sludge and deposits
  • Anti-oxidants help prevent oil breakdown, preventing engine-clogging sludge and deposit formation
  • Designed to combat low-speed pre-ignition in gasoline direct-injected engines, ensuring optimal performance and protection for modern aging vehicles.
See More

Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
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Most Popular 2026 Lexus RX350 Coolant/Antifreezes

Customize your Lexus with 2 Coolant/Antifreeze products like Engine Coolant and Antifreeze, all priced under $24.99.

ZEREX – Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon (Part No.675130)

Asian Vehicle Red 50/50 Ready-to-Use Antifreeze / Coolant, 1 Gallon

from

$22.99
ZEREX Asian Vehicle Antifreeze/Coolant is specifically formulated to meet the requirements of Asian vehicle manufacturers (Toyota®, Lexus®, Scion® and others) requiring a red, silicate free Hybrid Organic Acid Technology (HOAT) with a phosphate additive. This patented formula is designed to replace the original fluid and provides protection from rust, corrosion, boil overs and freezing.

Product Features:
  • Formulated to replace the OEM fluid in Asian make vehicles such as Toyota®, Lexus®, Scion® and others requiring a red, silicate free HOAT antifreeze/coolant
  • Silicate-free, long-life, phosphate Hybrid Organic Acid Technology chemistry
  • The long life formula provides protection for all cooling system metals from rust and corrosion. The silicate free, borate free formula helps protect against harmful scale and deposits
  • Meets the following OEM and industry specifications: JIS K 2234-1994, Hyundai/KIA MS 591-08, Mitsubishi ES-64217, Ford WSS-M97B55-A, ASTM 3306, ASTM D4985, Federal Specification A-A-870A
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Pentosin – Pentofrost A4 HOAT Phosphated Asian 50/50 Prediluted Antifreeze / Coolant – 1 Gallon (Part No.8115209)

Pentofrost A4 HOAT Phosphated Asian 50/50 Prediluted Antifreeze / Coolant - 1 Gallon

from

$24.99
Pentofrost A4 is a phosphated organic acid technology (phosphated OAT); which is categorized as HOAT (hybrid organic acid technology) in the US market. Pentofrost A4 is suitable for all Asian vehicles using pink Antifreeze/Coolant. Pentofrost A4 does not contain any silicate, borate, nitrite or amine containing additives since these may harm your Asian vehicle. Do not mix with other coolants (especially silicated coolants), as this may cause el formation and clog your radiator. Pentofrost A4 is a PRE-DILUTED antifreeze for Asian vehicle applications in water-cooled engines. It contains phosphates and organic salts to protect all materials used in cooling systems for Asian vehicles. Pentofrost A4 is mixable with all phosphated OAT. Meets ASTM D-3306.

Product Features:
  • Manufactured to the OE applications specific formulation.
  • Manufactured to the exact spec of DIN and ASTM D-3306.
  • Protects against corrosion and cavitation.
  • Does not foam.
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Top Picks for 2026 Lexus RX350 Fluids

Upgrade Lexus RX350s with top-quality Fluids parts, including 7 OEM and aftermarket selections for your 2026 model.

Valvoline – MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.773775)

MaxLife Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$39.99
Valvoline MaxLife Multi-Vehicle ATF is a full-synthetic formulation with advanced additives to prevent the major causes of transmission breakdown and help extend transmission life.  Developed to help prevent leaks, maximize transmission performance, reduce transmission wear, and maintain smooth shifting longer than conventional fluids. It is suitable for use in a broad range of ATF applications including most Ford, GM, Toyota, Honda, Nissan, Hyundai, BMW, Mercedes, Volvo, VW & Audi. Recommended for use in the following applications: GM DEXRON-II, DEXRON-III, DEXRON-VI, Ford MERCON LV, Toyota/Lexus Type T, T-II, T-IV, WS, Honda/Acura, ATF-Z1, Nissan/Infiniti Matic-D, Matic-J, Matric-K, Matic-S, Hyundai/Kia SP-II, SP-III, SP-IV, SPH-IV, BMW 7045E, ETL 8072B, LA2634, LT71141, Allison C-4, Mercedes Benz NAG-1, Volvo 1161521, 1161540, 97340, 1273.41, and VW/Audi G-052-025-A2, G-052-162-A1. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base oils and long life friction modifiers to help improve smooth shifting, eliminate slippage and shudder, prevent clutch wear and improve drivability longer than conventional fluids
  • High-performance seal conditioners maintain and preserve the elasticity of seals to help prevent leaks in high mileage transmissions
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Valvoline – SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.VV975)

SynPower Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

from

$18.99
Valvoline SAE 75W-90 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our detergent package-based formulation contains Full Synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance. Protect your gears with Valvoline, the #1 gear oil brand.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION , ranging from -30F to 300F degrees
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALS where APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS THE PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2361
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Valvoline – Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon (Part No.882505)

Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Gallon

from

$59.99
Valvoline SAE 75W-90 Full Synthetic Gear Oil provides the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Engineered to outperform, our detergent package-based formulation contains Full Synthetic base stocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance. Protect your gears with Valvoline, the No. 1 gear oil brand.

Product Features:
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION , ranging from -30 Deg F to 300 Deg F
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTIONá, ranging from -30 Deg F to 300 Deg F
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • FIGHTS CORROSION AND RUST with emulsifying agents and safeguards against impurities, oxidation and thermal breakdown
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALS where APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP HYPOID DIFFERENTIALSáwhere APPI GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS THE PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Valvoline – Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon (Part No.820681)

Import Multi-Vehicle Automatic Transmission Fluid, 1 Gallon

from

$36.99
Valvoline Import Multi-Vehicle Automatic Transmission Fluid is specifically formulated for use in most Toyota, Nissan, Honda and other imported vehicles. It is formulated with all synthetic base stocks and a proprietary additive system to ensure optimal transmission performance in a wide variety of vehicles. Valvoline Import Multi-Vehicle ATF can also be used in many domestic vehicles. It meets requirements of General Motors and Ford vehicles. Recommended for use in the following applications: Ford MERCON®, GM DEXRON®-II and DEXRON®-III, BMW LT 71141 and ETL-7045E, Nissan/Infiniti Nissan ATF, Matic-D, Matic-K and Matic-J, Mitsubishi Diamond SP-II and SP-III, Subaru ATF-HP, Hyundai/ KIA SP-II and SP-III , Toyota/Lexus Type T, T-III and T-IV , Honda/Acura ATF-Z1 (except in CVTs) , Mercedes Benz NAG1 , Volvo passenger car (except AW-1), and Volkswagen/Audi TL52162. For CVT applications Valvoline recommends Valvoline Full Synthetic CVT Fluid.

Product Features:
  • Formulated with full-synthetic base stocks and advanced additive technology to meet the challenging demands of automatic transmissions
  • Enhanced anti-shudder protection for smooth shifting and maximum power transfer
  • Developed with anti-wear technology to help improve transmission durability
  • Engineered with a proprietary blend of base oils and advanced additives to provide better oil flow at low temperatures and greater film protection at higher temperatures
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Valvoline – Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart (Part No.889785)

Flex Fill Transmission & Differential Gear Oil: Full Synthetic 75W-90, 1 Quart

from

$18.99
We’ve squeezed innovation into every ounce of Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil, the ultimate gear protection in hypoid rear differentials and non-synchronized manual transmissions. Our unique new flexible pouch makes getting into the tightest places to lubricate gears easier than ever and with less waste. The superior detergent package-based formulation contains fully synthetic basestocks and special additives that help protect parts from rust and corrosion while providing exceptional high and low temperature protection and excellent thermal stability, especially in demanding driving situations such as towing and off-roading. It contains an extreme pressure additive for better load carrying capacity, wear resistance additives that assist in protecting gear teeth, a limited slip additive for optimal clutch pack performance, and an anti-foaming agent for better lubrication and service life. Valvoline FlexFill SAE 75W-90 Full Synthetic Gear Oil is recommended for use in axle applications requiring factory-fill or drain-and-fill levels for limited slip performance.

Product Features:
  • FLEXIBLE POUCH FOR EASIER USE WITH LESS WASTE in tight, hard to reach undercarriage situations.
  • EXCEPTIONAL HIGH AND LOW TEMPERATURE PROTECTION ranging from -30F to 300F degrees for dependable coverage year-round
  • REDUCES CHATTERING AND PROTECTS GEAR TEETH from oxidation, rust, and wear
  • MEETS THE DEMANDS OF CONVENTIONAL AND LIMITED SLIP REAR DIFFERENTIALS where API GL-5 is specified, as well as non-synchronized manual transmissions that require API GL-4 or MT-1 fluid
  • MEETS OR EXCEEDS PERFORMANCE REQUIREMENTS for Mack GO-H and GO-J; API GL-5 and API MT-1; MIL-PRF-2105E; and SAE J2360
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Castrol – Transmax ATF / CVT Universal Automatic Transmission Fluid (1 Gallon) (Part No.15E0C8)

Transmax ATF / CVT Universal Automatic Transmission Fluid (1 Gallon)

from

$28.99
Castrol Transmax ATF/CVT Universal is a technologically advanced full-synthetic formulation designed to deliver excellent performance in most of the traditional stepped automatic transmissions and Continuously Variable Transmissions currently in use. It is also suitable for use in hybrids.

Product Features:
  • Coverage of over 300 specs/95% of vehicles in operation
  • Broad scope of vehicle applications improves workshop efficiency and inventory management
  • Enhanced friction durability for smooth transmission performance
  • Superior high temperature protection to effectively resist oxidation
  • ATF Applications: Dexron VI (Dexron III, Dexron), Mercon LV (Mercon SP, Mercon V, Mercon), JASO 1A (03), JASO 1A LV (13), Toyota T IV, Toyota T III, Toyota WS, Honda/Acura DW 1/Z 1, Nissan Matic D, Matic J, Matic S, Hyundai/Kia SP IV, SP III
  • ATF Applications: Mazda ATF M-V, M-III, FZ, Mitsubishi SP IV, SP III, IIM, II, PA, J3, VW/Audi (6, 8 & 9 speed automatics), BMW/Mini (6, 8 and 9 speed automatics), Jaguar/Land Rover (6, 8 & 9 speed automatics), Porsche (6, 8 & 9 speed automatics)
  • ATF Applications: Volvo (6, 8 and 9 speed automatics), Volvo Transmission Oil 97342, AT102, Mercedes-Benz (7 and 9 speed automatics)
  • CVT Applications: Toyota CVT Fluid TC, Toyota CVT Fluid FE , Nissan CVT Fluid NS-1, Nissan CVT Fluid NS-2, Nissan CVT Fluid NS-3, Subaru i-CVT Fluid, Subaru i-CVT FG, Subaru Lineartronic High Torque Chain CVTF, Honda HCF-2
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Valvoline – Extended Protection Automatic Transmission Fluid, 1 Quart (Part No.899179)

Extended Protection Automatic Transmission Fluid, 1 Quart

from

$15.99
Modern transmissions are better than ever, with more gears to help improve fuel efficiency and acceleration. Greater performance calls for greater protection. Valvoline Extended Protection Full Synthetic ATF features our exclusive Dual Defense Additive Technology for two layers of protection against metal-on-metal contact and thermal breakdown, all while minimizing wear on clutch components. In fact, Valvoline Extended Protection Full Synthetic ATF is 45% stronger against breakdown compared to major brand DEX/MERC oxidative PDSC performance. Proven to maximize transmission life, our patented formula is suitable for use in 92% of vehicles in light duty automatic transmissions 2010 and newer. Keep your modern vehicle shifting smoothly, mile after mile, with the ultimate protection you can only expect from Valvoline, the #1 ATF brand.

Product Features:
  • The ultimate protection for your automatic transmission
  • 45% stronger against breakdown
  • Dual Defense Additive Technology combines friction modifiers and anti-wear additives for two layers of protection
  • Suitable for use in over 92% of vehicles in light duty automatic transmissions 2010 and newer
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Top-Rated Fluids and Chemicals Brands For Your 2026 Lexus RX350

Shop for the best-rated brands offering Fluids and Chemicals and other products for your 2026 Lexus RX350s. Below you’ll find some of our best rated Fluids and Chemicals from Valvoline, ZEREX, and Pentosin, and more. Fluids and Chemicals from these brands that fit a 2026 RX350 start at just $18.99 and are rated as high as 4.8 stars. OEM and aftermarket Fluids and Chemicals don’t get more top quality, durable, and affordable than from the brands below.

Popular Valvoline 2026 Lexus RX350 Fluids and Chemicals

When it comes to maintaining or upgrading your 2026 Lexus RX350, using quality Fluids and Chemicals is essential to ensure durability and a perfect fit. Valvoline ticks all of those boxes. We offer a wide selection of Valvoline Fluids and Chemicals, specifically designed for the 2026 Lexus RX350. With over 3 Valvoline brand Fluids and Chemicals in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $18.99, with an average price of just $32.66. Plus, with over 1,177 customer reviews and an average rating of 4.8 stars, you can trust that our Valvoline Fluids and Chemicals will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart
from $38.99
(367)
Full Synthetic High Mileage 0W-20 Motor Oil, Maximizes Engine Life, 5 Quart
“great value never diasppoints”

Popular ZEREX 2026 Lexus RX350 Fluids and Chemicals

ZEREX auto parts is one of the highest quality Fluids and Chemical brands in the market. Any 2026 Lexus RX350 owner should feel confident when installing genuine ZEREX parts in their vehicle. To ensure the best fit and performance for your 2026 RX350, Advance Auto Parts carries a full inventory of 1 ZEREX Fluids and Chemicals. Plus you will be keeping your Lexus in peak condition while saving money because prices on these ZEREX Fluids and Chemicals range up to $22.99, plus, with more than 241 customer reviews and an impressive 4.8 stars average rating, you can be confident the Fram Fluids and Chemicals below will deliver on both quality and value.

FAQs for 2026 Lexus RX350 Fluids and Chemicals

Which Fluids and Chemicals are best-sellers for 2026 Lexus RX350s?

Out of 12 Fluids and Chemicals that fit 2026 Lexus RX350s, the following parts are the top sellers:

What’s the price range for 2026 Lexus RX350 Fluids and Chemicals?

Fluids and Chemical prices for the 2026 Lexus RX350 start at $14.99 and go up to $104.99 for the most premium parts.

What’s the average price of a Fluids and Chemical for a 2026 Lexus RX350?

The average price for Fluids and Chemicals for the 2026 Lexus RX350 is $35.57. Keep in mind the variety of part types within our Fluids and Chemical category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Fluids and Chemicals for other Lexus RX350 model years?

Yes, we currently carry Fluids and Chemicals for 18 model years of Lexus RX350s between 2007 and 2025. Fluids and Chemicals are bought most frequently for the following model years: 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, and 2015.

What are the cheapest Fluids and Chemicals for my 2026 Lexus RX350?

What are the top-rated Fluids and Chemicals that fit the 2026 Lexus RX350?

Out of 1,836 reviews by customers, our 2026 Lexus RX350 Fluids and Chemicals have an average customer rating of . These are some of the highest-rated Fluids and Chemical types for the 2026 Lexus RX350 and their top-rated products:

What types of Fluids and Chemicals do you sell for my 2026 Lexus RX350?

Can I get help with 2026 Lexus RX350 Fluids and Chemical orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Lexus Fluids and Chemicals and more.

What is your return policy for Lexus RX350 Fluids and Chemicals?

Advance Auto Parts keeps returns simple. For new Lexus RX350 Fluids and Chemicals and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.