2025 Chevrolet Express 4500 Cooling and Climate Controls

Essential Cooling and Climate Controls for 2025 Chevrolet Express 4500s

Carquest Premium – Blower Motor: with Wheel (Part No.75788)

Blower Motor: with Wheel

from

$104.99
Carquest Premium Blower Motors are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile A/C experience, fix it once and fix it right with Carquest Premium Blower Motors. Meets or exceeds OE design. Magnetic size and properties compare or exceed OEM.Windings meet or exceed OEM Specifications. Motor RPM equivalent to or exceeds OEM motor.

Product Features:
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
  • Meets or exceeds OE design and performance
  • Magnetic size and properties compare or exceed OEM
  • Windings meet or exceed OEM specifications
  • Motor RPM equivalent to or exceeds OEM motor
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GM Genuine Parts – Black Multi-Purpose Pigtail (Part No.PT2726)

Black Multi-Purpose Pigtail

from

$30.49
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Carquest Premium – A/C Standard Temp Automatic Adjusting Orifice Tube (Part No.T38902)

A/C Standard Temp Automatic Adjusting Orifice Tube

from

$19.79
Carquest Orifice Tubes are designed to regulate the flow of refrigerant through the air conditioning system to provide optimal cooling to the passenger compartment. Each orifice tube is manufactured to original equipment specifications to perform its function even in the harshest climates. Each part is supplied with the necessary gaskets and o-rings for installation.

Product Features:
  • The bodies of these expansion valves are machined from a single block of aluminum or brass metal.
  • Each expansion valve has settings for tonnage and superheat based on the vehicle specifications.
  • Each expansion valve is tested for function and leakage according to OEM specifications to ensure optimal performance of the air conditioning system.
  • O-Rings necessary for installation are included.
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GM Genuine Parts – Air Conditioning Service Valve (Part No.15-5438)

Air Conditioning Service Valve

from

$7.49
GM Genuine Parts A/C Service Valves are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These spring-loaded valves allow service access to the A/C system. The service valves allow the service technician to evacuate and recharge the refrigerant in the A/C system. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repairs leaking A/C system
  • Restores A/C function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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NTK – Engine Coolant Temperature Sensor (Part No.EF0173)

Engine Coolant Temperature Sensor

from

$34.99
The Engine Coolant Temperature Sensor determines the exact temperature of the engine coolant by sending an analog signal to the ECM to ensure proper air/fuel ratio along with proper operation of the cooling fans and temperature gauge. The Engine Coolant Temperature Sensor may be located on the cylinder head, engine block, thermostat housing or intake manifold. Reasons for replacement include, check engine light illumination, erratic or no temperature gauge operation, erratic or no cooling fan operation, and engine overheating.

Product Features:
  • OE MATCHED: Wires and probe length match OE. Mounting clips included where applicable
  • FASTER RESPONSE TIME: Thermal conductive grease inside brass housing increases sensor response time
  • THE DIFFERENCE: Thread sealant/o-ring installed where applicable. Thermistor placement within the housing matches OE to ensure proper output. Proper thermal conductive grease to provide accurate temperature transfer to the thermistor
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Bosch – Coolant Temperature Sensor (Part No.0280130122)

Coolant Temperature Sensor

from

$34.99
Bosch OE quality temperature sensors for accurate measurements with high durability, fast response time and wide measuring range.

Product Features:
  • Bosch OE quality temperature sensors for accurate measurements
  • Bosch OE quality temperature sensors with high durability against operating materials
  • Fast response time with Bosch OE quality temperature sensors
  • Bosch OE quality temperature sensors with a wide measuring range
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Carquest Premium – A/C Clutch Cycle Switch (Part No.ACA1743)

A/C Clutch Cycle Switch

from

$36.49
Carquest Premium Vehicle Solutions provides high-quality solutions for a wide range of applications. The HVAC Pressure Sensor/Switch monitors the refrigerant pressure within the air conditioning system, ensuring optimal performance and preventing potential system damage, which enhances climate control and passenger comfort. Engineered for maximum performance and durability, our products are built to excel in even the most demanding conditions, ensuring reliable operation and long-lasting value.

Product Features:
  • Durable Construction: Designed with high-quality materials to withstand harsh environmental conditions, ensuring long-lasting performance in extreme temperatures, vibrations, and moisture exposure.
  • Precision Engineering: Accurate sensing and switching capabilities provide reliable performance, reducing the risk of malfunctions and improving vehicle safety and efficiency.
  • Easy Installation & Maintenance: Designed for quick installation and minimal upkeep, reducing downtime and repair costs for both manufacturers and consumers.
  • Fit/Form/Function: Each vehicle electronic component is engineered to meet or surpass OEM standards, ensuring precise fit, optimal functionality, and reliable performance.
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GM Genuine Parts – Air Conditioning Clutch Cycling Switch (Part No.15-50618)

Air Conditioning Clutch Cycling Switch

from

$44.99
GM Genuine Parts A/C Compressor Pressure Delay Switches are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Air Conditioning Condenser (Part No.15-62890)

Air Conditioning Condenser

from

$247.99
GM Genuine Parts A/C Condensers are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These condensers are heat exchangers typically located in front of the engine radiator. The condenser dissipates heat absorbed by the refrigerant from the evaporator and from the compressor to the outside air. Hot refrigerant gas passes through tubes, where heat is removed, causing it to turn into a liquid. The air flowing through the fins carries the heat away. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Brazed and mechanically bonded aluminum construction for OE durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – A/C Condenser (Part No.2153)

A/C Condenser

from

$203.99
The Carquest condenser is an integral component of the motor vehicle air conditioning system. This part condenses the refrigerant into a liquid to prepare it for entry into the compressor. The condenser is manufactured according to OEM design specifications to ensure a long life with quality performance. Exact design standards produce a seamless fit into the engine compartment.

Product Features:
  • This is a parallel flow condenser that contains small micro-channels. It is highly recommended that this condenser be replaced if a failure has occurred in the vehicle’s air conditioning system that has resulted in debris contaminating the system.
  • The Carquest condenser production process includes quality driven details such as using zinc-coated tubes and electrostatic paint spray at high temperatures to provide the best corrosion resistance and durability in our condensers.
  • Continuous molds, laser welding machines, semi-automatic assembly stations and other advanced equipment provide quality products.
  • Each condenser uses only the highest quality raw materials including pure aluminum (not substandard or recycled) to provide the highest quality standards from beginning to finished product.
  • All brackets are designed per OEM specifications to ensure strength and reduce vibration and movement.
  • We leak test 100% of our condensers in helium leak test chambers to ensure the product does not leak.
  • Our condensers are manufactured from rigid design standards to fit OEM dimensions.
  • Each condenser design endures a series of tests that includes performance testing, vibration testing, blast testing, and salt spray testing to simulate real world conditions.
  • Each Carquest condenser is packaged using superior box construction. This box is easy to open and seal. Each condenser is packaged in the box with internal protection to keep the part centered and away from the package edges.
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GM Genuine Parts – Air Conditioning Accumulator (Part No.15-10345)

Air Conditioning Accumulator

from

$96.99
GM Genuine Parts A/C Accumulators are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These accumulators are used in A/C systems with an orifice tube metering device. The accumulator is located between the evaporator and the compressor, and serves to capture and store excess liquid refrigerant. This prevents liquid refrigerant from entering the compressor where it can damage the compressor. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Removes harmful moisture from the A/C refrigerant system
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Carquest Premium – A/C Accumulator (Part No.T83238)

A/C Accumulator

from

$79.99
Carquest Accumulators and Receiver Driers are designed to store, filter and dry the air conditioning refrigerant to provide proper performance and durability for the air conditioning system. They are manufactured to meet or exceed original equipment specifications.

Product Features:
  • All parts meet or exceed original equipment standards for moisture absorption, pressure and temperature resistance, air tightness, vibration resistance, corrosiveness, and pulse pressure.
  • Desiccant is 100% tested and assembled in a controlled environment to ensure performance meets or exceeds original equipment standards.
  • All accumulators and receiver driers are helium leak tested prior to packaging.
  • O-Rings necessary for installation are included.
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GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)

Air Conditioning System Valve Core

from

$14.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repair leaking A/C system, restore A/C function
  • Helps restore A/C Function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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Factory Air – Cap & Valve A/C System Seal Kit (Part No.26775)

Cap & Valve A/C System Seal Kit

from

$18.99
Our products are engineered and tested to provide years of trouble free operation. Backed by over 50 years of mobile a/c experience, fix it once and fix it right with Factory Air.

Product Features:
  • All the seals needed to complete the job
  • Compatible with both R12 and R134a refrigerants
  • SUV and rear air applications
  • Application specific
  • All the seals needed to complete the job
  • Compatible with both R12 and R134a refrigerants
  • SUV and rear air applications
  • Application specific
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GM Genuine Parts – Water Inlet Seal (Part No.12587397)

Water Inlet Seal

from

$8.99
GM Genuine Parts Engine Coolant Thermostat Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help close and prevent coolant from leaking out of your vehicle’s cooling system components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps close and prevent coolant from leaking out of your vehicle’s cooling system components to maintain the proper engine temperature
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Heating and Air Conditioning Vacuum Harness (Part No.15-75212)

Heating and Air Conditioning Vacuum Harness

from

$30.99
Heating and Air Conditioning Vacuum Harness

Carquest Premium – Radiator Cap: 15 PSI (Part No.10248)

Radiator Cap: 15 PSI

from

$15.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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Dorman – HD Solutions – Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack (Part No.902-5601)

Engine Coolant Reservoir Cap: Twist, Plastic, 1 Pack

from

$23.79
Cracked or lost the original engine coolant reservoir cap? Replace it seamlessly and effectively with this precisely engineered, direct replacement cap.

Product Features:
  • Direct replacement – this engine coolant reservoir cap directly replaces a cracked or lost original cap
  • Application specific – made to match dimensions of reservoir cap on only certain vehicle years, makes and models
  • Seamless fit – reverse-engineered from the original equipment to fit perfectly
  • Excellent value – a quick, easy replacement that’s less expensive than going back to the dealership
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GM Genuine Parts – Temperature Valve Actuator (Part No.15-71845)

Temperature Valve Actuator

from

$86.99
ACDelco GM Original Equipment HVAC Air Valve Actuator is a GM-recommended replacement component for one or more of the following vehicle systems: hvac. This original equipment actuator will provide the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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ACDelco – Multi-Purpose Pigtail (Part No.PT2319)

Multi-Purpose Pigtail

from

$53.99
ACDelco Professional Throttle Position Sensor Connector is a high quality aftermarket replacement component for one or more of the following vehicle systems: ignition, starting and charging, body-electrical and lighting, and/or engine fuel management. This premium aftermarket connector is manufactured to meet or exceed your expectations for fit, form, and function.

Product Features:
  • Professional, premium aftermarket replacement
  • Provides the performance and dependability you expect from ACDelco
  • Manufactured to meet expectations for fit, form, and function
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Carquest Premium – Multi-Use Connector (Part No.PTA1017)

Multi-Use Connector

from

$30.99
Modern vehicles may have 100 or more electrical harness connectors in every operating system of the vehicle. Terminal tension may weaken with time or corrosion may occur within the connector housing making replacement necessary. When replacing any harness-connector assembly approved wire termination methods must be followed to ensure a successful and long-term solution to the original problem is made. A failed terminal connection, terminal corrosion or damaged wire will result in an electrical system fault.

Product Features:
  • Carquest electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • WVE electrical connectors meet or exceed OE wire gauge, insulation, and terminal material requirements.
  • Product constructed to meet all design and operating characteristics as intended by the manufacturer.
  • OE specified wire gauge to ensure a reliable electrical connection
  • Designed to meet or exceed OE specifications in form, fit and function
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GM Genuine Parts – 2-Way Female Black and Green Multi-Purpose Pigtail (Part No.PT248)

2-Way Female Black and Green Multi-Purpose Pigtail

from

$29.49
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Heater Water Flow Control Valve (Part No.15-51278)

Heater Water Flow Control Valve

from

$103.99
GM Genuine Parts HVAC Heater Water Flow Control Valves are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These HVAC heater water flow control valves control the flow of engine coolant through the heater core. The heater water flow control valve is closed when maximum AC cooling is selected. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Visual- and leak-tested for durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Heating and Air Conditioning Blower Control Module (Part No.15-81796)

Heating and Air Conditioning Blower Control Module

from

$96.99
ACDelco GM Original Equipment HVAC Blower Motor Resistors provide stepped voltage drops to provide multiple blower fan speeds and are GM-recommended replacements for your vehicle’s original components. This original equipment blower motor resistor has been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Restores blower speed control caused by a failed resistor
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Upgrade your 2025 Chevrolet Express 4500 with Top-Quality Cooling and Climate Controls

When it comes to maintaining or upgrading your 2025 Chevrolet Express 4500, nothing is more important than using high-quality OEM or aftermarket parts that you can trust. Whether you’re repairing damage to your Chevrolet or enhancing its overall performance, Cooling and Climate Controls are key to keeping your Express 4500 functioning at its best. At Advance Auto Parts, we offer a wide selection of 18 Cooling and Climate Controls for the 2025 Chevrolet Express 4500, designed to meet your needs without breaking the bank. From Blend Door replacements to Engine Cooling Parts upgrades, we’ve got you covered with parts that fit your vehicle perfectly and ensure long-lasting performance.

Affordable Prices and Wide Selection

Shopping for Cooling and Climate Controls for any vehicle can be a hassle, especially if you’re on a budget. But with Advance Auto Parts, you can find high-quality Cooling and Climate Controls for your 2025 Chevrolet Express 4500 at great prices. Our Cooling and Climate Controls inventory for this model ranges from just $7.49 to $247.99, with an average price of $64.98. Our 18 Cooling and Climate Controls in stock come from 2 trusted brands, so you’re sure to find the right part for your 2025 Chevrolet Express 4500 without overspending.

Top Brands and High Customer Satisfaction

Advance Auto Parts takes pride in offering only the best brands in the automotive industry. For your 2025 Chevrolet Express 4500, we stock popular OEM and aftermarket Cooling and Climate Controls from top names like GM Genuine, and more. GM Genuine Cooling and Climate Controls start at just $7.49 and boast an impressive 4.5 stars average rating from customers. With 21 customer reviews and counting, our 2025 Chevrolet Express 4500 Cooling and Climate Controls have a strong track record of reliability, ensuring you can trust your purchase.

Explore Related Parts and More

While you’re here, don’t forget to check out other essential categories that go hand in hand with Cooling and Climate Control upgrades. Explore related part types like Transmission Parts, Ignition and Tune-Up Products and more to make sure your 2025 Chevrolet Express 4500 is always ready to roll. We’re committed to providing you with everything you need to keep your Express 4500 in top shape, all in one place. Start shopping confidently below for your 2025 Chevrolet Express 4500!

Best-Selling Blend Doors for 2025 Chevrolet Express 4500s

Enhance the driving experience in your Chevrolet with 1 quality Blend Door components, starting at $86.99.

GM Genuine Parts – Temperature Valve Actuator (Part No.15-71845)

Temperature Valve Actuator

from

$86.99
ACDelco GM Original Equipment HVAC Air Valve Actuator is a GM-recommended replacement component for one or more of the following vehicle systems: hvac. This original equipment actuator will provide the same performance, durability, and service life you expect from General Motors.

Product Features:
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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Most Popular 2025 Chevrolet Express 4500 Engine Cooling Parts

Customize your Chevrolet with 3 Engine Cooling Parts products like Coolant Reservoir Caps, Coolant Temperature Sensors, and Engine Coolant Water Inlet Seals, all priced under $39.99.

Carquest Premium – Reservoir Cap (Part No.T80)

Reservoir Cap

from

$39.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
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GM Genuine Parts – Engine Coolant Temperature Sensor (Part No.25186240)

Engine Coolant Temperature Sensor

from

$25.99
ACDelco GM Original Equipment Engine Coolant Temperature Sensors monitor engine temperature, and are GM-recommended replacements for your vehicle’s original components. The engine temperature signal is used by the engine control module to adjust the air/fuel mixture and ignition timing. These original equipment engine coolant temperature sensors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Helps keep engine running at proper temperature
  • Alerts vehicle operator of high engine temperature conditions
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Water Inlet Seal (Part No.12587397)

Water Inlet Seal

from

$8.99
GM Genuine Parts Engine Coolant Thermostat Seals are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These seals help close and prevent coolant from leaking out of your vehicle’s cooling system components. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Helps close and prevent coolant from leaking out of your vehicle’s cooling system components to maintain the proper engine temperature
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Genuine Parts are designed, engineered and tested to rigorous standards, and are backed by General Motors
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Top Picks for 2025 Chevrolet Express 4500 Air Conditioning Parts

Upgrade Chevrolet Express 4500s with top-quality Air Conditioning Parts parts, including 10 OEM and aftermarket selections for your 2025 model.

GM Genuine Parts – Air Conditioning Service Valve (Part No.15-5438)

Air Conditioning Service Valve

from

$7.49
GM Genuine Parts A/C Service Valves are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These spring-loaded valves allow service access to the A/C system. The service valves allow the service technician to evacuate and recharge the refrigerant in the A/C system. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repairs leaking A/C system
  • Restores A/C function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

GM Genuine Parts – Air Conditioning Orifice Tube (Part No.15-5151)

Air Conditioning Orifice Tube

from

$13.29
GM Genuine Parts A/C Orifice Tubes are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These tubes, which separate the high and low pressure sides of the air conditioning system, control the flow of low pressure liquid refrigerant into the evaporator. The orifice tube is essentially a calibrated restriction located at the inlet to the evaporator. This causes the necessary pressure drop to allow the liquid refrigerant to evaporate within the evaporator and absorb heat. Since the orifice tube is fixed, the system is regulated by either cycling the compressor clutch or by a variable displacement compressor. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Restores A/C performance due to restricted orifice tubes
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

GM Genuine Parts – Air Conditioning System Valve Core (Part No.15-1119)

Air Conditioning System Valve Core

from

$14.99
GM Genuine Parts A/C System Valve Cores are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These A/C system valve cores are components of the A/C service valve through which your vehicle’s refrigerant can be accessed and serviced. The valve core is a spring-loaded poppet valve that is opened when the service technician connects the A/C service machine hose couplers. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Repair leaking A/C system, restore A/C function
  • Helps restore A/C Function
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

GM Genuine Parts – Black Multi-Purpose Pigtail (Part No.PT2726)

Black Multi-Purpose Pigtail

from

$30.49
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Air Conditioning Clutch Cycling Switch (Part No.15-50618)

Air Conditioning Clutch Cycling Switch

from

$44.99
GM Genuine Parts A/C Compressor Pressure Delay Switches are designed, engineered, and tested to rigorous standards, and are backed by General Motors. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Air Conditioning Condenser (Part No.15-62890)

Air Conditioning Condenser

from

$247.99
GM Genuine Parts A/C Condensers are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These condensers are heat exchangers typically located in front of the engine radiator. The condenser dissipates heat absorbed by the refrigerant from the evaporator and from the compressor to the outside air. Hot refrigerant gas passes through tubes, where heat is removed, causing it to turn into a liquid. The air flowing through the fins carries the heat away. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Brazed and mechanically bonded aluminum construction for OE durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Air Conditioning Accumulator (Part No.15-10345)

Air Conditioning Accumulator

from

$96.99
GM Genuine Parts A/C Accumulators are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These accumulators are used in A/C systems with an orifice tube metering device. The accumulator is located between the evaporator and the compressor, and serves to capture and store excess liquid refrigerant. This prevents liquid refrigerant from entering the compressor where it can damage the compressor. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Removes harmful moisture from the A/C refrigerant system
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
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GM Genuine Parts – Multi-Purpose Pigtail (Part No.PT1346)

Multi-Purpose Pigtail

from

$83.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – 10-Way Female White Multi-Purpose Pigtail (Part No.PT150)

10-Way Female White Multi-Purpose Pigtail

from

$111.99
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
See More

GM Genuine Parts – 2-Way Female Black and Green Multi-Purpose Pigtail (Part No.PT248)

2-Way Female Black and Green Multi-Purpose Pigtail

from

$29.49
ACDelco GM Original Equipment Pigtail Connectors are connectors ready to be spliced into vehicle harnesses, and are GM-recommended replacements for your vehicle’s original components. These original equipment pigtail connectors have been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Protective outer coverings help provide long-lasting durability
  • Color-coded wires allow for easy installation
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
See More

In-Demand Blower Motor and Related Products for 2025 Chevrolet Express 4500s

Select from 2 premium Blower Motor and Related Products parts for your 2025 Chevrolet Express 4500, with prices ranging from $93.99 to $96.99.

GM Genuine Parts – Heating and Air Conditioning Blower Control Module (Part No.15-81796)

Heating and Air Conditioning Blower Control Module

from

$96.99
ACDelco GM Original Equipment HVAC Blower Motor Resistors provide stepped voltage drops to provide multiple blower fan speeds and are GM-recommended replacements for your vehicle’s original components. This original equipment blower motor resistor has been manufactured to fit your GM vehicle, providing the same performance, durability, and service life you expect from General Motors.

Product Features:
  • Restores blower speed control caused by a failed resistor
  • GM-recommended replacement part for your GM vehicle’s original factory component
  • Offering the quality, reliability, and durability of GM OE
  • Manufactured to GM OE specification for fit, form, and function
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GM Genuine Parts – Heating and Air Conditioning Blower Motor (Part No.15-81950)

Heating and Air Conditioning Blower Motor

from

$93.99
GM Genuine Parts HVAC Blower Motors are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These HVAC blower motors are electric fans located in the HVAC housing. The fan pushes air through the heater core and evaporator and into the cabin. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Permanently lubricated, self-aligning bearings designed for long life and dependable performance
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Most Sold 2025 Chevrolet Express 4500 Heating Parts

Explore our best-selling Chevrolet parts for the 2025 Express 4500 among 1 OEM and aftermarket options starting from $103.99.

GM Genuine Parts – Heater Water Flow Control Valve (Part No.15-51278)

Heater Water Flow Control Valve

from

$103.99
GM Genuine Parts HVAC Heater Water Flow Control Valves are designed, engineered, and tested to rigorous standards, and are backed by General Motors. These HVAC heater water flow control valves control the flow of engine coolant through the heater core. The heater water flow control valve is closed when maximum AC cooling is selected. GM Genuine Parts are the true OE parts installed during the production of or validated by General Motors for GM vehicles. Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE).

Product Features:
  • Visual- and leak-tested for durability
  • Some GM Genuine Parts may have formerly appeared as ACDelco GM Original Equipment (OE)
  • GM Engineers design and validate OE parts specifically for your Chevrolet, Buick, GMC, or Cadillac vehicle
  • Original equipment parts are designed to work with your GM vehicle safety systems — aftermarket replacement parts may not meet the same OE safety regulations, depending on the part type
  • GM regularly updates production and service part designs to integrate new materials and technologies
See More

Top-Rated Cooling and Climate Controls Brands For Your 2025 Chevrolet Express 4500

Shop for the best-rated brands offering Cooling and Climate Controls and other products for your 2025 Chevrolet Express 4500s. Below you’ll find some of our best rated Cooling and Climate Controls from GM Genuine, and more. Cooling and Climate Controls from these brands that fit a 2025 Express 4500 start at just $7.49 and are rated as high as 4.5 stars. OEM and aftermarket Cooling and Climate Controls don’t get more top quality, durable, and affordable than from the brands below.

Popular GM Genuine 2025 Chevrolet Express 4500 Cooling and Climate Controls

When it comes to maintaining or upgrading your 2025 Chevrolet Express 4500, using quality Cooling and Climate Controls is essential to ensure durability and a perfect fit. GM Genuine ticks all of those boxes. We offer a wide selection of GM Genuine Cooling and Climate Controls, specifically designed for the 2025 Chevrolet Express 4500. With over 3 GM Genuine brand Cooling and Climate Controls in stock, you’re sure to find what you need. The prices for these top-notch parts start as low as $7.49, with an average price of just $11.92. Plus, with over 21 customer reviews and an average rating of 4.5 stars, you can trust that our GM Genuine Cooling and Climate Controls will get the job done right. Choose Advance Auto Parts for reliability, quality, and expert-approved parts that keep your vehicle running strong.
Air Conditioning Orifice Tube
from $13.29
(8)
Air Conditioning Orifice Tube
“Can’t say it is an exact replacement. Opened lines to remove old one and found there wasn’t one. Anyway it works.”
Air Conditioning Service Valve
from $7.49
(7)
Air Conditioning Service Valve
“Thanks”
Air Conditioning System Valve Core
from $14.99
(6)
Air Conditioning System Valve Core
“Goof”

FAQs for 2025 Chevrolet Express 4500 Cooling and Climate Controls

Which Cooling and Climate Controls are best-sellers for 2025 Chevrolet Express 4500s?

Out of 18 Cooling and Climate Controls that fit 2025 Chevrolet Express 4500s, the following parts are the top sellers:

What’s the price range for 2025 Chevrolet Express 4500 Cooling and Climate Controls?

Cooling and Climate Control prices for the 2025 Chevrolet Express 4500 start at $7.49 and go up to $247.99 for the most premium parts.

What’s the average price of a Cooling and Climate Control for a 2025 Chevrolet Express 4500?

The average price for Cooling and Climate Controls for the 2025 Chevrolet Express 4500 is $64.98. Keep in mind the variety of part types within our Cooling and Climate Control category so you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Cooling and Climate Controls for other Chevrolet Express 4500 model years?

Yes, we currently carry Cooling and Climate Controls for 15 model years of Chevrolet Express 4500s between 2009 and 2024. Cooling and Climate Controls are bought most frequently for the following model years: 2023, 2022, 2021, 2020, 2019, 2018, 2017, 2016, and 2015.

What are the cheapest Cooling and Climate Controls for my 2025 Chevrolet Express 4500?

The cheapest 2025 Chevrolet Express 4500 Cooling and Climate Controls we carry in stock are:

What types of Cooling and Climate Controls do you sell for my 2025 Chevrolet Express 4500?

As of 11/2/25, these are some of the most in-demand types of Cooling and Climate Controls for a 2025 Chevrolet Express 4500:

Can I get help with 2025 Chevrolet Express 4500 Cooling and Climate Control orders?

Contact our customer support team, by chat or phone, through the help desk page, where you can find instant answers about Chevrolet Cooling and Climate Controls and more.

What is your return policy for Chevrolet Express 4500 Cooling and Climate Controls?

Advance Auto Parts keeps returns simple. For new Chevrolet Express 4500 Cooling and Climate Controls and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.