2022 Lexus RX450h Differentials

Keep Your 2022 Lexus RX450h in Top Shape with a Quality Differential

When it comes to maintaining or upgrading your 2022 Lexus RX450h, choosing high-quality parts is crucial for ensuring your vehicle stays in top shape, whether you’re tackling a repair or enhancing performance. At Advance Auto Parts, we know how important it is to find the right Differential for your RX450h. We currently carry a top Differential in stock that is built to last. Whether you’re replacing a damaged Differential or looking to upgrade, our selection for the 2022 Lexus RX450h ensures you’ll find exactly what you need to keep your vehicle looking and performing its best.

Explore Related Parts

And while you’re here, don’t forget to check out related part categories like Drive Shafts and Axles and Spindles to complete your upgrade or repair project. At Advance Auto Parts, we’re proud to offer the parts and expertise to keep your 2022 Lexus RX450h running smoothly and looking great.

Essential 2022 Lexus RX450h Differentials

Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
See More

Idemitsu – Type TLS-LV Automatic Transmission Fluid, 1 Quart (Part No.30040096-75000C)

Type TLS-LV Automatic Transmission Fluid, 1 Quart

from

$14.49
Formulated to meet the specific requirements of Toyota, Lexus, and Scion vehicles equipped with conventional (non-CVT) transmissions that require the use of Toyota ATF WS. Recommended for service-fill in all Toyota, Lexus, and Scion automatic transmissions where ATF WS is specified. Fuel economy demands and more sophisticated electronic controls have made automatic transmissions not only more complex, but also unique to each vehicle manufacturer. Long gone are the days of having just a couple choices of automatic transmission fluid type. IDEMITSU is the factory fill Automatic Transmission Fluid (ATF) supplier to most Asian imports. IDEMITSU application-specific ATF products match the exact friction materials and performance requirements of each different vehicle model for which they are made.

Product Features:
  • Precisely engineered frictional characteristics guarantee smooth shifting and outstanding anti-shudder performance
  • Optimized viscosity and advanced friction reducing additive technology provide exceptional fuel economy performance
  • Excellent resistance to oxidation and thermal breakdown provide long fluid life and extended protection
  • Exceptional wear protection of gears and bearings
  • Provides superior deposit control and protects metal surfaces from rust and corrosion
  • Excellent seal compatibility and conditioning reduces risk of fluid leaks due to seal shrinkage, hardening and cracking
See More

Most Popular Differential Oil for 2022 Lexus RX450hs

Enhance your 2022 Lexus RX450h with this popular Differential Oil we have in stock, for $14.99.

Valvoline – Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart (Part No.898795)

Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart

from

$14.99
Valvoline is the No. 1 ATF brand, and now we’ve taken it to the next level with our hybrid performance fluid: Valvoline Full Synthetic Hybrid Automatic Transmission Fluid. Specifically designed for hardworking hybrids, Valvoline Full Synthetic Hybrid ATF is suitable for use in more than 95% of hybrid vehicles in operation with registered US ATF full hybrid vehicles (not including mild hybrids, traditional CVT or DCT hybrid models). Valvoline Full Synthetic Hybrid ATF is proven to maximize transmission life, and it’s compatible with copper and the coatings on copper in hybrid transmission, providing greater oxidation stability, insulation for the electrical current, and increased heat transfer capabilities to protect against transmission failure. Look for Valvoline’s complete lineup of hybrid performance fluids, including motor oil and antifreeze/coolant ¿ from the brand trusted for over 150 years.

Product Features:
  • Full synthetic hybrid ATF with Copper Care Technology, from the No. 1 ATF brand
  • Enhanced protection against corrosion that can result in hybrid transmission failure
  • Protects electrical systems maximizing transmission efficiency
  • Increased heat transfer capabilities to protect against higher temperatures produced by hybrids
See More

FAQs for 2022 Lexus RX450h Differentials

What’s the price range for 2022 Lexus RX450h Differentials?

We currently have just one Differentials for the 2022 Lexus RX450h in stock: Hybrid ATF Full Synthetic Automatic Transmission Fluid, 1 Quart and it costs $14.99.

Does Advance Auto Parts sell Differentials for other Lexus RX450h model years?

Yes, we carry Differentials for 11 model years of Lexus RX450hs between 2010 and 2021. The following model years are the most popular for Differential purchases: 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

Does Advance Auto Parts sell Differentials for any other 2022 Lexus models?

Yes. We stock Differentials for 8 other popular 2022 Lexus models. Some of the most popular are 2022 RX350 Differentials, 2022 GX460 Differentials, 2022 IS300 Differentials, 2022 IS350 Differentials, and 2022 RC350 Differentials.

What types of Differentials do you sell for my 2022 Lexus RX450h?

We currently have just 1 Differential in stock for a 2022 Lexus RX450h, and as of 11/2/25, it is a Differential Oil.

Can I get help with 2022 Lexus RX450h Differential orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Differentials and more.

What is your return policy for Lexus RX450h Differentials?

Advance Auto Parts keeps returns simple. For new Lexus RX450h Differentials and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.