2022 Lexus IS350 Engine Cooling Parts

Keep Your 2022 Lexus IS350 in Top Shape with Quality Engine Cooling Parts

Whether you’re repairing or upgrading your Engine Cooling Part, using high-quality parts is key to keeping your 2022 Lexus IS350 looking sharp and performing at its best. At Advance Auto Parts we carry a wide selection of dependable options, including Radiators, Coolant Temperature Sensors, and Coolant Reservoir Caps. Whether you’re replacing a damaged part or enhancing your truck’s style and protection, you’ll find exactly what you need to get the job done right.

Top-Rated Engine Cooling Parts from Trusted Brands

Looking for a reliable Engine Cooling Part? We’ve got you covered with options from brands you know and trust like Carquest Premium. For example, Carquest Premium Engine Cooling Parts start at just $10.99 with an average 4.4 star rating. With over 4 reviews and a solid 4 star average, you can shop with confidence knowing other Lexus IS350 owners approve.

Explore Related Parts

While you’re upgrading or replacing your Engine Cooling Part, don’t forget to check out other key components like Air Conditioning Parts and Blower Motor and Related Products. At Advance Auto Parts, we’re here to help you keep your 2022 Lexus IS350 in peak condition, inside and out.

Essential 2022 Lexus IS350 Engine Cooling Parts

Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)

Radiator Fan Assembly: Dual, Cost Effective and Reliable

from

$453.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
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Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-576)

Radiator Fan Assembly: Dual, Cost Effective and Reliable

from

$541.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
See More

KAI – Radiator (Part No.RAD2968)

Radiator

from

$88.99
New Platinum Pro Radiator, 2.5 And 3.5 Liter Engines, Automatic Transmission

Product Features:
  • 2.5 And 3.5 Liter Engines, Automatic Transmission, Made Of Plastic and Aluminum
  • Meets All Federal Motor Safety Standards
  • No Drilling Needed For Installation
  • No Modifications Needed For Installation
  • Direct Fit Replacement For Your Vehicle
  • Same Form Fit And Function As OE
  • Radiator Cap Not Included
  • Check Out The Large Selection Of Parts Available For Your Vehicle
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Carquest Premium – Radiator (Part No.813477)

Radiator

from

$178.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Carquest Premium – Radiator (Part No.812968)

Radiator

from

$257.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

DENSO – Engine Coolant Temperature Sensor (Part No.193-1000)

Engine Coolant Temperature Sensor

from

$99.99
DENSO’s engine coolant temperatures sensors are manufactured to the strictest OE standards resulting in superior efficiency. OE quality with precise sensing elements. Exact fit which controls fuel injection ignition timing and transmission shifting.

Product Features:
  • OE technology adapted for the aftermarket
  • Reduces emissions, increased performance
  • Delivers the highest reliability and detection accuracy
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Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)

Coolant Temperature Sensor 1TS1172

from

$65.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
See More

AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8003)

TEMPERATURE SENSOR

from

$48.99
TEMPERATURE SENSOR

Factory Air – Coolant Temp Sensor Switch (Part No.36424)

Coolant Temp Sensor Switch

from

$34.05
High quality OE replacement part with all components needed to complete the job

Product Features:
  • Contains gaskets, O-rings, or seals to properly replace the product
  • Brass construction for accurate temperature sensing
  • Color coded for easy identification
  • Zinc coated terminal to resist corrosion
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Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)

Engine Coolant Reservoir Cap

from

$10.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Carquest Premium – Radiator Cap: 16 PSI (Part No.10242)

Radiator Cap: 16 PSI

from

$16.99
Crafted to meet the exact specifications set by Original Equipment Manufacturers (OEM), these products are engineered for effortless installation and removal. Constructed from premium-grade components, incorporating proper relief and vacuum valves, they ensure optimal performance even in the most demanding automotive cooling systems. Rigorously quality-tested, these components provide exceptional, out-of-the-box performance and superior durability to meet or exceed the highest standards of today’s vehicles.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Most Popular Radiator for 2022 Lexus IS350s

Enhance your 2022 Lexus IS350 with this popular Radiator we have in stock, for $178.99.

Carquest Premium – Radiator (Part No.813477)

Radiator

from

$178.99
Carquest Premium radiators are designed and engineered for maximum performance, using the highest-grade materials to ensure all radiators meet or exceed original equipment (O.E.) fit, form and function. Carquest Premium radiators are built by manufacturers that meet IATF 16949 certified framework, an internationally recognized proof of quality in the automotive industry. Most modern vehicles use radiators with plastic tanks and our parts are engineered with integrated ribbing to prevent damage during thermal cycling. Carquest Premium radiators are also 100% tested to ensure a durable, leak-free cooling system repair.

Product Features:
  • Thermal tested under real-life temperature simulations
  • High tensile strength aluminum for maximum crimp strength
  • Plastic tanks are engineeredáwith integrated ribbingáfor addedástrength to withstand cracks, bowing and distortion during thermal cycles
  • Thermal expansion slots extend core life and reduce failure rates by allowing improved core expansion and contraction during systematic heat cycles
See More

Best-Selling 2022 Lexus IS350 Coolant Temperature Sensors

Upgrade your IS350 with one of our 2 best-selling Coolant Temperature Sensors.

Carquest Premium – Coolant Temperature Sensor 1TS1172 (Part No.WTC2071)

Coolant Temperature Sensor 1TS1172

from

$65.99
Product Features:
  • Designed to meet or exceed OE specifications for fit, form and function
  • 100% factory resistance calibrated to ensure precision tolerances, resulting in extremely accurate temperature for optimal performance
  • OE precision matched thermistor ensuring Carquest sensors match OE output resistances across all temperature positions
  • O-rings, seals or thread sealant are included if required
  • Weather-tight connectors prevent leaks and corrosion for longer life
  • Extensive design validation testing and 100% end-of-line tested
  • Carquest Vehicle Solutions Technical Support available from ASE certified technicians: 1-866-687-5413
See More

AISIN – TEMPERATURE SENSOR (Part No.THSAZ-8003)

TEMPERATURE SENSOR

from

$48.99
TEMPERATURE SENSOR

Top-Quality Coolant Reservoir Caps for 2022 Lexus IS350s

Choose a high-quality OEM or aftermarket Coolant Reservoir Cap for Lexus IS350s and enjoy top-notch performance from $10.99.

Carquest Premium – Engine Coolant Reservoir Cap (Part No.10254)

Engine Coolant Reservoir Cap

from

$10.99
Manufactured to meet all OEM specifications. Designed to be easy to install and remove. Manufactured from high quality components with proper relief and vacuum valves. Quality tested to stand up to even the most demanding automotive cooling systems.

Product Features:
  • Maintains proper cooling system pressure
  • Easy installation and removal
  • 100% tested to ensure proper pressure and longevity
  • Meets all OEM specifications
See More

Our Top Pick for a 2022 Lexus IS350 Radiator Fan Motor

Invest in a durable Radiator Fan Motor for your 2022 Lexus, knowing you’re getting trusted brands and expert craftsmanship.

Dorman – Radiator Fan Assembly: Dual, Cost Effective and Reliable (Part No.620-498)

Radiator Fan Assembly: Dual, Cost Effective and Reliable

from

$453.99
This engine cooling fan assembly is precision-engineered to match the fit and performance of the stock radiator fan on specific vehicle years, makes and models. It has been rigorously tested to ensure it cools as effectively as the original part.

Product Features:
  • Ideal replacement – this engine cooling fan assembly was precision-engineered to match the fit and performance of the stock radiator fan assembly on specific vehicles
  • Complete package – assembly is designed with the same materials and components as the original part
  • Quality assured – motors are tested in laboratory settings to ensure performance
  • Cost effective and reliable – trustworthy manufacturing for far less than same part at the dealership
See More

Top-Rated Engine Cooling Part Brands For Your 2022 Lexus IS350

When it comes to finding the perfect Engine Cooling Part for your 2022 Lexus IS350, Advance Auto Parts has you covered with a wide selection of high-quality OEM and aftermarket options from 3 trusted brands. We carry the most popular Engine Cooling Part brands including Carquest Premium, and more, all known for their exceptional customer ratings (average brand rating of 4.4 stars) and competitive prices, as low as $10.99. Purchasing a Engine Cooling Part from us here at Advance Auto Parts is a smart move for both you and your 2022 Lexus IS350, providing peace of mind with parts that meet or exceed OEM standards.

Popular Carquest Premium 2022 Lexus IS350 Engine Cooling Parts

If you’re looking for a top-quality Engine Cooling Part for your 2022 Lexus IS350, Advance Auto Parts has exactly what you need with our selection of Carquest Premium Engine Cooling Parts. We have 1 Carquest Premium Engine Cooling Parts in stock for this fitment, all known for their durability and precision fit. With prices starting at just $10.99, you’ll find the perfect Engine Cooling Part for your needs and budget. Carquest Premium Engine Cooling Parts for the 2022 Lexus IS350 come highly rated, with over 4 customer reviews and an impressive average rating of 4.4 stars. Choosing a Carquest Premium Engine Cooling Part from Advance Auto Parts is a smart move to ensure quality and value for your vehicle.
Engine Coolant Reservoir Cap
from $10.99
(4)
Engine Coolant Reservoir Cap
“I had a difficult time finding a coolant reservoir cap for a Toyota Prius. Advance was the only place in town that carried them.”

FAQs for 2022 Lexus IS350 Engine Cooling Parts

What are the best-selling Engine Cooling Parts for 2022 Lexus IS350s?

Out of 5 Engine Cooling Parts that fit 2022 Lexus IS350s, the following parts are the top sellers:

What’s the price range for 2022 Lexus IS350 Engine Cooling Parts?

The prices of Engine Cooling Parts for the 2022 Lexus IS350 range from $10.99 up to $453.99 for the most premium parts.

What is the average price of an Engine Cooling Part for a 2022 Lexus IS350?

The average price for Engine Cooling Parts for the 2022 Lexus IS350 is $151.79. Keep in mind the variety of part types within our Engine Cooling Part category, where you are likely to find a wide range of prices across a variety of parts and components.

Does Advance Auto Parts sell Engine Cooling Parts for other Lexus IS350 model years?

Yes, we carry Engine Cooling Parts for 18 model years of Lexus IS350s between 2006 and 2025. The following model years are the most popular for Engine Cooling Part purchases: 2021, 2020, 2019, 2018, 2017, 2016, 2015, 2014, and 2013.

What are the cheapest Engine Cooling Parts for my 2022 Lexus IS350?

The cheapest 2022 Lexus IS350 Engine Cooling Parts we carry are:

Does Advance Auto Parts sell Engine Cooling Parts for any other 2022 Lexus models?

Yes. We stock Engine Cooling Parts for 9 other popular 2022 Lexus models. Some of the most popular are 2022 ES350 Engine Cooling Parts, 2022 RX350 Engine Cooling Parts, 2022 GX460 Engine Cooling Parts, 2022 ES250 Engine Cooling Parts, and 2022 IS300 Engine Cooling Parts.

What are the top-rated Engine Cooling Parts that fit the 2022 Lexus IS350?

The one 2022 Lexus IS350 Engine Cooling Part we have in stock is the Engine Coolant Reservoir Cap. It is rated 4 stars and costs $10.99.

What types of Engine Cooling Parts do you sell for my 2022 Lexus IS350?

As of 11/2/25, these are some of the most in-demand types of Engine Cooling Parts for a 2022 Lexus IS350:

Can I get help with 2022 Lexus IS350 Engine Cooling Part orders?

Contact our customer support team by chat or phone, through the help desk page, where you can find instant answers about Lexus Engine Cooling Parts and more.

What is your return policy for Lexus IS350 Engine Cooling Parts?

Advance Auto Parts keeps returns simple. For new Lexus IS350 Engine Cooling Parts and accessories, your online orders can be returned, in their original condition, within 45 days. For requirements, see the returns page.